phrog_2439 is made of 61 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
369.15 558 365


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p298790 no NCBI prot ID no annotation VI_12393 Spirochaetia_gi_452719437 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p383445 no NCBI prot ID no annotation VI_05552 Betaproteobacteria_gi_485035531 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Peduovirus.
p159422 no NCBI prot ID no annotation VI_03849 Gammaproteobacteria_gi_218547440_2755040_2795034 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p48863 no NCBI prot ID no annotation VI_03932 Gammaproteobacteria_gi_568136993_3261974_3319642 Viruses.
p112855 no NCBI prot ID no annotation VI_11121 Gammaproteobacteria_gi_487671041_536018_580278 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p440692 no NCBI prot ID no annotation VI_05529 Betaproteobacteria_gi_149156612_0_7186 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p210173 no NCBI prot ID no annotation VI_04108 Actinobacteria_gi_484048417 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p204513 no NCBI prot ID no annotation VI_04114 Actinobacteria_gi_419859811 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p175736 no NCBI prot ID no annotation VI_09309 Gammaproteobacteria_gi_485067757 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p275628 no NCBI prot ID no annotation VI_09652 Gammaproteobacteria_gi_458775987_356067_385385 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p74066 no NCBI prot ID no annotation VI_02578 Gammaproteobacteria_gi_491286131_396353_445164 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vieuvirus; Acinetobacter virus B1251; Acinetobacter phage YMC/09/02/B1251.
p167865 no NCBI prot ID no annotation VI_09310 Gammaproteobacteria_gi_483370937 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p24857 no NCBI prot ID no annotation VI_09535 Gammaproteobacteria_gi_481021442 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p66609 no NCBI prot ID no annotation VI_02470 Gammaproteobacteria_gi_333069176 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p6929 no NCBI prot ID no annotation VI_09232 Gammaproteobacteria_gi_452736179 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p30758 no NCBI prot ID no annotation VI_07732 Gammaproteobacteria_gi_483976866 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Hollowayvirus; Pseudomonas virus F116; Pseudomonas phage F116.
p13058 no NCBI prot ID no annotation VI_09223 Gammaproteobacteria_gi_452735834_8512_93839 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p152764 no NCBI prot ID no annotation VI_09261 Gammaproteobacteria_gi_452738055 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p73696 no NCBI prot ID no annotation VI_08937 Gammaproteobacteria_gi_395794507 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p80841 no NCBI prot ID no annotation VI_01018 Bacteroidia_gi_330998596_63767_111518 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p43448 no NCBI prot ID no annotation VI_04569 Bacilli_gi_485455588 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p35207 no NCBI prot ID no annotation VI_00711 Bacilli_gi_507055493_2793767_2856861 Viruses.
p180472 no NCBI prot ID no annotation VI_01248 Clostridia_gi_547833238 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p64861 no NCBI prot ID no annotation VI_03739 Gammaproteobacteria_gi_510926785_3022545_3073049 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p348904 no NCBI prot ID no annotation VI_10612 Gammaproteobacteria_gi_486162058 Viruses.
p336775 no NCBI prot ID no annotation VI_06991 Gammaproteobacteria_gi_416320642_0_21494 Viruses.
p70337 no NCBI prot ID no annotation VI_03698 Gammaproteobacteria_gi_510916008_767725_817349 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p251135 no NCBI prot ID no annotation VI_01739 Gammaproteobacteria_gi_545282974_114025_145799 Viruses.
p291145 no NCBI prot ID no annotation VI_07679 Gammaproteobacteria_gi_478762516_121775_148783 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p268685 no NCBI prot ID no annotation VI_04551 Bacilli_gi_485066299 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_029022_p31 YP_009219397.1 XRE family transcriptional regulator NC_029022 Clostridium phage phiCT9441A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p281856 no NCBI prot ID no annotation VI_06138 Clostridia_gi_545049359 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p212963 no NCBI prot ID no annotation VI_12436 Spirochaetia_gi_523647848 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p333395 no NCBI prot ID no annotation VI_06893 Gammaproteobacteria_gi_452240516 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p376961 no NCBI prot ID no annotation VI_10525 Gammaproteobacteria_gi_485907270 Viruses.
p311252 no NCBI prot ID no annotation VI_04027 Negativicutes_gi_485070723 Viruses.
p193737 no NCBI prot ID no annotation VI_00097 Alphaproteobacteria_gi_560138247 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p379782 no NCBI prot ID no annotation VI_10521 Gammaproteobacteria_gi_485900587 Viruses.
p153957 no NCBI prot ID no annotation VI_04550 Bacilli_gi_485066273_238_40694 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p91787 no NCBI prot ID no annotation VI_02958 Gammaproteobacteria_gi_510916172 Viruses.
p234954 no NCBI prot ID no annotation VI_03494 Gammaproteobacteria_gi_455737153_2257785_2291092 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p412155 no NCBI prot ID no annotation VI_06226 Deltaproteobacteria_gi_115379634 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_011398_p72 YP_002290948.1 putative phage DNA-binding protein NC_011398 Clostridium virus phiCD27 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Lubbockvirus.
p62903 no NCBI prot ID no annotation VI_01527 Gammaproteobacteria_gi_545234203 Viruses.
EU719189_p72 ACH91363.1 putative phage DNA-binding protein EU719189 Clostridium virus phiCD27 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Lubbockvirus.
p115188 no NCBI prot ID no annotation VI_07919 Gammaproteobacteria_gi_419145910 Viruses.
p241335 no NCBI prot ID no annotation VI_05738 Betaproteobacteria_gi_348618597 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p379610 no NCBI prot ID no annotation VI_10516 Gammaproteobacteria_gi_485894084 Viruses.
p364996 no NCBI prot ID no annotation VI_10608 Gammaproteobacteria_gi_486156685 Viruses.
p376125 no NCBI prot ID no annotation VI_10514 Gammaproteobacteria_gi_485892558 Viruses.
KU252585_p34 ALY07668.1 XRE family transcriptional regulator KU252585 Gordonia phage Howe Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p365888 no NCBI prot ID no annotation VI_06136 Clostridia_gi_545049023 Viruses.
p76362 no NCBI prot ID no annotation VI_09148 Gammaproteobacteria_gi_421683688 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p342397 no NCBI prot ID no annotation VI_09131 Gammaproteobacteria_gi_445451213 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vieuvirus; Acinetobacter virus B1251; Acinetobacter phage YMC/09/02/B1251.
p308281 no NCBI prot ID no annotation VI_09816 Gammaproteobacteria_gi_520952737 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p30115 no NCBI prot ID no annotation VI_10214 Gammaproteobacteria_gi_470946471 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p307398 no NCBI prot ID no annotation VI_09812 Gammaproteobacteria_gi_520928733 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p360073 no NCBI prot ID no annotation VI_09810 Gammaproteobacteria_gi_520926852 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p308764 no NCBI prot ID no annotation VI_09814 Gammaproteobacteria_gi_520950882 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p59279 no NCBI prot ID no annotation VI_01715 Gammaproteobacteria_gi_545273063_50162_102553 Viruses.
p354867 no NCBI prot ID no annotation VI_02330 Gammaproteobacteria_gi_476380946 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_5786 22 no annotation unknown function 22 0 1000
phrog_96 937 HNH endonuclease DNA, RNA and nucleotide metabolism 8 6.36E-15 5.32
phrog_11126 9 no annotation unknown function 8 4.73E-36 26.45
phrog_15813 6 no annotation unknown function 6 0 1000
phrog_17839 5 no annotation unknown function 5 0 1000
phrog_26280 3 no annotation unknown function 3 0 1000
phrog_17098 5 no annotation unknown function 3 1.10E-15 6.08
phrog_32170 2 no annotation unknown function 2 0 1000
phrog_35814 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1124 transcriptional regulator transcription regulation 94.4 0.0035 8-63 / 8-65
phrog_1233 no annotation unknown function 91.8 0.028 169-232 / 24-88
phrog_13326 no annotation unknown function 95.5 0.00061 9-112 / 5-106
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 94.2 0.0046 7-46 / 7-46
phrog_1373 transcriptional regulator transcription regulation 98.4 3.4E-10 8-66 / 33-91
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 97.7 6.2E-08 3-73 / 6-76
phrog_14076 transcriptional regulator transcription regulation 94.4 0.0036 6-58 / 1-55
phrog_1468 transcriptional repressor transcription regulation 95.6 0.00051 8-65 / 9-65
phrog_147 transcriptional regulator transcription regulation 96.1 0.00012 7-69 / 3-67
phrog_1516 no annotation unknown function 98.6 3.8E-11 135-276 / 20-175
phrog_1702 transcriptional repressor transcription regulation 94.5 0.0031 3-69 / 10-79
phrog_17822 no annotation unknown function 91.8 0.028 8-72 / 9-72
phrog_18104 transcriptional regulator transcription regulation 94.5 0.0029 7-60 / 3-54
phrog_18342 transcriptional repressor transcription regulation 90.2 0.059 11-69 / 22-82
phrog_18577 no annotation unknown function 98.2 1.6E-09 131-241 / 116-243
phrog_19114 no annotation unknown function 90.3 0.056 4-59 / 69-123
phrog_1914 no annotation unknown function 99.4 8.5E-17 128-278 / 10-178
phrog_19315 no annotation unknown function 99.1 1.5E-14 128-283 / 10-189
phrog_19579 transcriptional regulator transcription regulation 91.8 0.029 15-62 / 11-58
phrog_1994 DNA binding protein DNA, RNA and nucleotide metabolism 95.8 0.00029 9-69 / 2-62
phrog_20936 no annotation unknown function 92.6 0.018 181-224 / 24-67
phrog_2104 no annotation unknown function 96.7 1.4E-05 5-62 / 44-101
phrog_2328 transcriptional repressor transcription regulation 97.9 1.4E-08 7-70 / 16-79
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.6 1.8E-05 10-64 / 28-83
phrog_2967 transcriptional regulator transcription regulation 98.0 1.2E-08 5-69 / 7-72
phrog_32768 no annotation unknown function 95.0 0.0016 6-63 / 9-67
phrog_34341 transcriptional regulator transcription regulation 92.5 0.019 5-53 / 70-117
phrog_34939 no annotation unknown function 96.2 0.0001 8-69 / 11-73
phrog_3557 transcriptional regulator transcription regulation 92.4 0.021 7-69 / 14-75
phrog_35675 antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 91.2 0.04 5-48 / 5-48
phrog_35 transcriptional repressor transcription regulation 94.3 0.0041 19-58 / 13-52
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.3 0.00086 3-61 / 3-62
phrog_38027 transcriptional repressor transcription regulation 95.7 0.00041 8-66 / 59-117
phrog_3949 transcriptional repressor transcription regulation 92.1 0.025 21-63 / 30-71
phrog_3 transcriptional repressor transcription regulation 98.0 9.3E-09 5-66 / 2-63
phrog_4031 no annotation unknown function 94.2 0.0044 10-66 / 519-576
phrog_409 transcriptional regulator transcription regulation 90.2 0.06 13-41 / 5-32
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 91.8 0.028 15-41 / 16-42
phrog_4268 transcriptional repressor transcription regulation 95.2 0.0011 8-63 / 37-90
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.3 0.0039 8-65 / 6-64
phrog_4583 transcriptional repressor transcription regulation 95.9 0.0002 8-69 / 12-73
phrog_4739 no annotation unknown function 95.8 0.00031 8-69 / 69-130
phrog_4779 transcriptional regulator transcription regulation 95.2 0.0011 8-45 / 3-40
phrog_4836 CII-like regulator transcription regulation 97.6 1.8E-07 8-69 / 84-145
phrog_4 transcriptional repressor transcription regulation 96.9 5.5E-06 8-69 / 5-62
phrog_5301 transcriptional repressor transcription regulation 91.7 0.031 15-61 / 19-67
phrog_5823 transcriptional regulator transcription regulation 97.6 1.8E-07 5-147 / 3-124
phrog_6223 transcriptional repressor transcription regulation 92.8 0.015 16-50 / 14-49
phrog_6288 no annotation unknown function 90.2 0.061 6-58 / 11-65
phrog_638 transcriptional regulator transcription regulation 95.0 0.0015 8-99 / 4-88
phrog_6463 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.4 4.6E-05 10-69 / 24-91
phrog_6499 transcriptional regulator transcription regulation 95.6 0.00043 8-139 / 8-147
phrog_6831 transcriptional regulator transcription regulation 96.3 7E-05 13-57 / 9-55
phrog_6962 no annotation unknown function 94.5 0.0029 7-52 / 2-47
phrog_7241 transcriptional regulator transcription regulation 98.1 3.2E-09 11-64 / 66-119
phrog_7396 no annotation unknown function 95.4 0.00068 5-69 / 11-77
phrog_7950 transcriptional repressor transcription regulation 96.0 0.00016 2-43 / 5-46
phrog_87 metallo-protease other 99.3 4.8E-16 150-284 / 4-135
phrog_8 transcriptional regulator transcription regulation 98.4 2.8E-10 7-69 / 2-62
phrog_9103 transcriptional repressor transcription regulation 94.1 0.0048 4-69 / 4-70
phrog_955 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.2 0.012 6-54 / 36-84
phrog_9908 DNA binding protein DNA, RNA and nucleotide metabolism 94.7 0.0022 8-61 / 16-69

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF06114.12 IrrE N-terminal-like domain 3.2E-10 174-294 / 4-124
PF13058.5 Protein of unknown function (DUF3920) 1.2E-08 188-260 / 54-123
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 6.7E-06 21-84 / 8-77
PF14247.5 Putative metallopeptidase 1E-05 204-289 / 84-152
PF14590.5 Domain of unknown function (DUF4447) 1.9E-05 20-86 / 4-73
PF05339.10 Protein of unknown function (DUF739) 2.3E-05 24-83 / 4-63
PF01381.21 Helix-turn-helix 2.4E-05 29-81 / 2-54
PF13744.5 Helix-turn-helix domain 2.7E-05 21-83 / 16-79
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 2.7E-05 27-86 / 2-61
PF13413.5 Helix-turn-helix domain 4.9E-05 29-80 / 2-59
PF13443.5 Cro/C1-type HTH DNA-binding domain 5.4E-05 28-85 / 2-62
PF04645.11 Protein of unknown function, DUF603 5.8E-05 19-84 / 3-68
PF12844.6 Helix-turn-helix domain 6.6E-05 27-85 / 3-61
PF10463.8 Peptidase U49 0.00014 208-261 / 86-136
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.00021 23-83 / 69-128
PF13560.5 Helix-turn-helix domain 0.00022 25-82 / 3-63
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.00024 30-85 / 3-57
PF08667.9 BetR domain 0.00026 22-86 / 4-72
PF05269.10 Bacteriophage CII protein 0.00044 29-86 / 16-71
PF04228.12 Putative neutral zinc metallopeptidase 0.00072 190-260 / 145-233
PF08965.9 Domain of unknown function (DUF1870) 0.0007 25-75 / 3-55
PF14549.5 DNA-binding transcriptional regulator Cro 0.0016 28-82 / 2-52
PF13693.5 Winged helix-turn-helix DNA-binding 0.0016 26-85 / 5-61
PF00157.16 Pou domain - N-terminal to homeobox domain 0.0039 22-76 / 6-64
PF12725.6 Protein of unknown function (DUF3810) 0.0041 187-267 / 172-234
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0045 23-75 / 113-165
PF12116.7 Stage III sporulation protein D 0.005 34-78 / 17-62

Annotations of the NCBI proteins of this PHROG


2:XRE family transcriptional regulator 2:phage DNA-binding protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K18831 higA : HTH-type transcriptional regulator / antitoxin HigA no pathways 148 1

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003677 DNA binding
GO:0003700 DNA binding transcription factor activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated

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