phrog_2440 is made of 61 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
93.59 213 89


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p398665 no NCBI prot ID no annotation VI_12236 Halobacteria_gi_448406145_102907_117157 Viruses.
NC_004084_p49 NP_665966.1 Rep NC_004084 Natrialba phage PhiCh1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus.
p48063 no NCBI prot ID no annotation VI_12205 Halobacteria_gi_448285003 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus; Natrialba phage PhiCh1.
p47364 no NCBI prot ID no annotation VI_03977 Halobacteria_gi_289594273 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus; Natrialba phage PhiCh1.
p305133 no NCBI prot ID no annotation VI_12249 Halobacteria_gi_448543799_10614_35830 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p347476 no NCBI prot ID no annotation VI_12261 Halobacteria_gi_448671664_65692_85879 Viruses.
p305431 no NCBI prot ID no annotation VI_12250 Halobacteria_gi_448550861_23992_49182 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p353391 no NCBI prot ID no annotation VI_03994 Halobacteria_gi_482989397_13759_33075 Viruses.
p393557 no NCBI prot ID no annotation VI_12265 Halobacteria_gi_448681465_135912_150818 Viruses.
p335243 no NCBI prot ID no annotation VI_12241 Halobacteria_gi_448460196_205347_227019 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p410812 no NCBI prot ID no annotation VI_03996 Halobacteria_gi_564288321_22075_34920 Viruses.
p305385 no NCBI prot ID no annotation VI_12251 Halobacteria_gi_448558771_8784_33975 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p410813 no NCBI prot ID no annotation VI_03996 Halobacteria_gi_564288321_22075_34920 Viruses.
p393876 no NCBI prot ID no annotation VI_12242 Halobacteria_gi_448466231_19110_33970 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p347477 no NCBI prot ID no annotation VI_12261 Halobacteria_gi_448671664_65692_85879 Viruses.
p393558 no NCBI prot ID no annotation VI_12265 Halobacteria_gi_448681465_135912_150818 Viruses.
p353390 no NCBI prot ID no annotation VI_03994 Halobacteria_gi_482989397_13759_33075 Viruses.
KY264020_p3 ARM71117.1 PhiH1-like repressor KY264020 Haloarcula hispanica pleomorphic virus 4 (HHPV4) Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; unclassified Betapleolipovirus.
p406671 no NCBI prot ID no annotation VI_12264 Halobacteria_gi_448680304_261073_274437 Viruses.
p393875 no NCBI prot ID no annotation VI_12242 Halobacteria_gi_448466231_19110_33970 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
KY264020_p4 ARM71118.1 PhiH1-like repressor KY264020 Haloarcula hispanica pleomorphic virus 4 (HHPV4) Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; unclassified Betapleolipovirus.
p406670 no NCBI prot ID no annotation VI_12264 Halobacteria_gi_448680304_261073_274437 Viruses.
p335242 no NCBI prot ID no annotation VI_12241 Halobacteria_gi_448460196_205347_227019 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p305134 no NCBI prot ID no annotation VI_12249 Halobacteria_gi_448543799_10614_35830 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p305384 no NCBI prot ID no annotation VI_12251 Halobacteria_gi_448558771_8784_33975 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p305432 no NCBI prot ID no annotation VI_12250 Halobacteria_gi_448550861_23992_49182 Viruses; unclassified viruses; unclassified DNA viruses; unclassified ssDNA viruses.
p351488 no NCBI prot ID no annotation VI_12216 Halobacteria_gi_448330764_14227_33803 Viruses.
CP003412_p4 PhiH1-like repressor no annotation CP003412 Natrinema SNJ2 provirus Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae.
p88556 no NCBI prot ID no annotation VI_12254 Halobacteria_gi_448592111 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_008695_p20 YP_919047.1 hypothetical protein NC_008695 Archaeal BJ1 virus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p430310 no NCBI prot ID no annotation VI_03979 Halobacteria_gi_410688693 Viruses.
p322685 no NCBI prot ID no annotation VI_12266 Halobacteria_gi_448683719_248199_271311 Viruses.
p367375 no NCBI prot ID no annotation VI_12217 Halobacteria_gi_448345507_100317_118155 Viruses.
p159268 no NCBI prot ID no annotation VI_03983 Halobacteria_gi_257386085_423263_463260 Viruses.
p354582 no NCBI prot ID no annotation VI_12220 Halobacteria_gi_448350073_138912_158077 Viruses.
p354223 no NCBI prot ID no annotation VI_12260 Halobacteria_gi_448664643_48834_68054 Viruses.
p70190 no NCBI prot ID no annotation VI_12256 Halobacteria_gi_448610561 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p335368 no NCBI prot ID no annotation VI_12263 Halobacteria_gi_448680304_178065_199729 Viruses.
p316961 no NCBI prot ID no annotation VI_12231 Halobacteria_gi_448376649_179780_203485 Viruses.
p345531 no NCBI prot ID no annotation VI_12248 Halobacteria_gi_448502870_13516_33994 Viruses.
p365722 no NCBI prot ID no annotation VI_03985 Halobacteria_gi_289579696_268989_287077 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HRPV3; Halorubrum pleomorphic virus 3.
p415803 no NCBI prot ID no annotation VI_12206 Halobacteria_gi_448291730_71576_83902 Viruses.
p355708 no NCBI prot ID no annotation VI_03990 Halobacteria_gi_344210305_2710849_2729862 Viruses.
p418077 no NCBI prot ID no annotation VI_03976 Halobacteria_gi_161561737 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus; Natrialba phage PhiCh1.
p51275 no NCBI prot ID no annotation VI_12275 Halobacteria_gi_484232361_1956327_2012832 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses.
p286248 no NCBI prot ID no annotation VI_12197 Halobacteria_gi_322371616 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses.
p341841 no NCBI prot ID no annotation VI_03991 Halobacteria_gi_336252096_3610642_3631645 Viruses.
p362801 no NCBI prot ID no annotation VI_12234 Halobacteria_gi_448386223_0_18400 Viruses.
p425851 no NCBI prot ID no annotation VI_12257 Halobacteria_gi_448623630_35790_47017 Viruses.
p51316 no NCBI prot ID no annotation VI_12275 Halobacteria_gi_484232361_1956327_2012832 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses.
p352769 no NCBI prot ID no annotation VI_03993 Halobacteria_gi_482989160_1666641_1686042 Viruses.
p355735 no NCBI prot ID no annotation VI_03997 Halobacteria_gi_564288321_2722282_2741295 Viruses.
p408642 no NCBI prot ID no annotation VI_12244 Halobacteria_gi_448473100_287_13395 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Archaeal BJ1 virus.
NC_030909_p9 YP_009273691.1 hypothetical protein NC_030909 Pseudomonas phage YMC11/07/P54_PAE_BP Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_002484_p41 YP_009173781.1 putative transcriptional regulator NC_002484 Pseudomonas virus D3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Detrevirus.
p34632 no NCBI prot ID no annotation VI_03090 Gammaproteobacteria_gi_553772214_118688_181900 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p141777 no NCBI prot ID no annotation VI_03998 Halobacteria_gi_529076460_2194204_2235794 Viruses.
p28288 no NCBI prot ID no annotation VI_08223 Gammaproteobacteria_gi_419703370_0_68180 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p17982 no NCBI prot ID no annotation VI_00036 Actinobacteria_gi_482936492 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
KU708004_p6 AMW64466.1 transcriptional regulator KU708004 Pseudomonas phage phiAH14a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p288006 no NCBI prot ID no annotation VI_04183 Alphaproteobacteria_gi_306840416 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_2440 61 transcriptional regulator transcription regulation 22 9.62E-83 73.14
phrog_1305 114 DNA binding protein DNA, RNA and nucleotide metabolism 3 1.03E-10 1.11
phrog_4029 35 no annotation unknown function 3 8.11E-13 3.21
phrog_13047 8 no annotation unknown function 2 1.42E-11 1.97
phrog_22659 3 no annotation unknown function 2 2.54E-13 3.72

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10724 no annotation unknown function 90.4 0.054 28-69 / 35-75
phrog_11195 no annotation unknown function 95.8 0.00031 37-75 / 49-93
phrog_11214 no annotation unknown function 90.4 0.056 14-59 / 55-98
phrog_1123 no annotation unknown function 94.7 0.0023 14-69 / 24-77
phrog_12156 DNA helicase DNA, RNA and nucleotide metabolism 94.8 0.0021 10-68 / 415-474
phrog_12817 transcriptional regulator transcription regulation 92.4 0.02 15-75 / 69-132
phrog_13512 transcriptional regulator transcription regulation 95.3 0.00094 15-77 / 10-85
phrog_1368 transcriptional regulator transcription regulation 96.6 2.2E-05 14-70 / 16-72
phrog_142 Ren-like exclusion protein moron, auxiliary metabolic gene and host takeover 96.7 1.3E-05 13-72 / 5-66
phrog_16668 no annotation unknown function 90.5 0.053 15-71 / 4-58
phrog_1687 MarR family transcrition regulator transcription regulation 95.9 0.00023 13-59 / 6-50
phrog_2030 transcriptional regulator transcription regulation 96.0 0.00015 1-73 / 4-85
phrog_25306 no annotation unknown function 92.3 0.021 10-78 / 16-79
phrog_31115 replication initiation protein DNA, RNA and nucleotide metabolism 95.3 0.00094 14-66 / 50-101
phrog_3288 transcriptional regulator transcription regulation 92.0 0.026 1-58 / 348-401
phrog_3502 no annotation unknown function 90.9 0.045 15-62 / 15-62
phrog_35756 no annotation unknown function 92.7 0.016 23-75 / 27-75
phrog_38164 no annotation unknown function 96.5 3.2E-05 9-71 / 8-67
phrog_4278 no annotation unknown function 96.3 7.4E-05 10-79 / 13-90
phrog_630 no annotation unknown function 93.5 0.0091 15-77 / 4-63
phrog_633 transcriptional regulator transcription regulation 95.6 0.00042 13-72 / 5-62
phrog_7387 transcriptional regulator transcription regulation 92.4 0.02 10-59 / 12-59
phrog_9285 no annotation unknown function 91.9 0.028 28-65 / 38-74
phrog_9799 no annotation unknown function 91.1 0.04 10-63 / 4-60

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF14557.5 Putative AphA-like transcriptional regulator 2.2E-08 59-134 / 8-95
PF14277.5 Domain of unknown function (DUF4364) 3.3E-08 62-130 / 3-74
PF03965.15 Penicillinase repressor 7.2E-08 59-125 / 3-73
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 9.7E-08 59-127 / 8-91
PF11313.7 Protein of unknown function (DUF3116) 1.1E-07 64-129 / 12-82
PF14394.5 Domain of unknown function (DUF4423) 1.9E-07 56-126 / 18-89
PF07381.10 Winged helix DNA-binding domain (DUF1495) 4E-07 58-125 / 8-87
PF04079.15 Segregation and condensation complex subunit ScpB 8E-07 58-127 / 82-150
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 1.3E-06 59-130 / 5-81
PF01090.18 Ribosomal protein S19e 1.6E-06 62-130 / 54-136
PF14947.5 Winged helix-turn-helix 1.6E-06 61-128 / 4-70
PF05584.10 Sulfolobus plasmid regulatory protein 1.7E-06 59-110 / 6-52
PF13601.5 Winged helix DNA-binding domain 1.7E-06 62-128 / 3-71
PF04492.12 Bacteriophage replication protein O 1.7E-06 59-118 / 27-92
PF02334.15 Replication terminator protein 2E-06 60-132 / 19-106
PF03551.13 Transcriptional regulator PadR-like family 2.5E-06 73-126 / 13-72
PF02002.16 TFIIE alpha subunit 2.6E-06 60-129 / 13-84
PF02319.19 E2F/DP family winged-helix DNA-binding domain 2.7E-06 64-109 / 12-56
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 2.9E-06 61-118 / 3-61
PF09639.9 YjcQ protein 3.1E-06 64-129 / 3-83
PF10711.8 Hypothetical protein (DUF2513) 3.3E-06 63-129 / 9-85
PF02295.16 Adenosine deaminase z-alpha domain 4.7E-06 61-110 / 6-53
PF09202.10 Rio2, N-terminal 5.9E-06 59-126 / 6-74
PF13463.5 Winged helix DNA-binding domain 6E-06 61-109 / 5-50
PF12793.6 Sugar transport-related sRNA regulator N-term 6.8E-06 64-131 / 7-77
PF16221.4 winged helix-turn-helix 7E-06 60-108 / 32-78
PF01638.16 HxlR-like helix-turn-helix 7.9E-06 59-127 / 5-75
PF04358.12 DsrC like protein 8.9E-06 58-110 / 38-95
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 9E-06 59-109 / 13-60
PF01475.18 Ferric uptake regulator family 9.7E-06 59-120 / 7-73
PF08461.9 Ribonuclease R winged-helix domain 1.2E-05 64-124 / 3-63
PF03428.12 Replication protein C N-terminal domain 1.2E-05 52-111 / 35-106
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 1.6E-05 73-126 / 23-74
PF07848.11 PaaX-like protein 2E-05 73-120 / 19-68
PF08784.10 Replication protein A C terminal 2.1E-05 59-109 / 40-94
PF05732.10 Firmicute plasmid replication protein (RepL) 2.2E-05 59-120 / 55-117
PF01978.18 Sugar-specific transcriptional regulator TrmB 2.2E-05 59-111 / 8-57
PF09114.9 Transcription factor MotA, activation domain 3.1E-05 59-131 / 16-83
PF09824.8 ArsR transcriptional regulator 3.1E-05 53-109 / 11-61
PF09012.9 FeoC like transcriptional regulator 3.3E-05 64-111 / 5-49
PF06163.10 Bacterial protein of unknown function (DUF977) 3.4E-05 59-110 / 12-60
PF13034.5 Protein of unknown function (DUF3895) 3.5E-05 59-110 / 3-67
PF09904.8 Winged helix-turn helix 4.1E-05 64-108 / 12-53
PF02082.19 Transcriptional regulator 4.9E-05 64-109 / 13-57
PF06969.15 HemN C-terminal domain 5.7E-05 64-122 / 11-64
PF16864.4 Dimerisation domain 7.7E-05 61-126 / 20-79
PF08222.10 CodY helix-turn-helix domain 8.4E-05 73-110 / 3-38
PF01316.20 Arginine repressor, DNA binding domain 9.2E-05 60-119 / 6-65
PF01726.15 LexA DNA binding domain 0.0001 74-110 / 25-60
PF14338.5 Mrr N-terminal domain 0.00011 88-126 / 49-85
PF09339.9 IclR helix-turn-helix domain 0.00014 64-109 / 8-51
PF01022.19 Bacterial regulatory protein, arsR family 0.00014 62-106 / 5-46
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.00015 59-111 / 8-57
PF05158.11 RNA polymerase Rpc34 subunit 0.0009 59-119 / 13-79
PF12802.6 MarR family 0.00018 62-110 / 8-55
PF04182.11 B-block binding subunit of TFIIIC 0.00018 61-110 / 4-52
PF01047.21 MarR family 0.00019 62-110 / 6-51
PF13412.5 Winged helix-turn-helix DNA-binding 0.00019 64-106 / 8-47
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0002 64-109 / 7-50
PF04703.11 FaeA-like protein 0.00021 64-110 / 5-48
PF08220.11 DeoR-like helix-turn-helix domain 0.00026 64-109 / 5-47
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00047 76-109 / 13-47
PF12840.6 Helix-turn-helix domain 0.00072 58-109 / 7-53
PF08535.9 KorB domain 0.00083 74-109 / 3-36
PF03297.14 S25 ribosomal protein 0.00086 63-109 / 46-89
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.00095 73-109 / 20-54
PF00392.20 Bacterial regulatory proteins, gntR family 0.001 73-109 / 22-57
PF13730.5 Helix-turn-helix domain 0.0014 85-106 / 33-52
PF15977.4 Winged helix-turn-helix DNA binding 0.0015 74-109 / 23-56
PF14502.5 Helix-turn-helix domain 0.0016 73-109 / 5-39
PF13545.5 Crp-like helix-turn-helix domain 0.0017 73-109 / 26-60
PF08279.11 HTH domain 0.0017 64-104 / 5-43
PF01418.16 Helix-turn-helix domain, rpiR family 0.0019 59-109 / 16-67
PF07037.10 Putative transcription regulator (DUF1323) 0.0021 76-130 / 2-56
PF08820.9 Domain of unknown function (DUF1803) 0.0026 59-119 / 12-65
PF09821.8 C-terminal AAA-associated domain 0.0027 79-127 / 2-45
PF07900.10 Protein of unknown function (DUF1670) 0.0036 59-110 / 77-129
PF05331.10 Protein of unknown function (DUF742) 0.0038 59-110 / 41-87
PF08679.10 Dissimilatory sulfite reductase D (DsrD) 0.0043 63-118 / 4-60
PF09756.8 DDRGK domain 0.0062 64-129 / 106-169
PF09397.9 Ftsk gamma domain 0.0066 64-110 / 10-53
PF07183.10 Protein of unknown function (DUF1403) 0.0071 60-110 / 275-320
PF00325.19 Bacterial regulatory proteins, crp family 0.0075 76-106 / 4-32

Annotations of the NCBI proteins of this PHROG


2:transcriptional regulator 2:PhiH1-like repressor 2:protein of an unannotated phage 1:hypothetical protein 1:Rep

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K11924 mntR : DtxR family transcriptional regulator, manganese transport regulator no pathways 280 1

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0007131 reciprocal meiotic recombination
GO:0004674 protein serine/threonine kinase activity
GO:0005622 intracellular
GO:0006383 transcription by RNA polymerase III
GO:0009289 pilus
GO:0006260 DNA replication
GO:0003677 DNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006468 protein phosphorylation
GO:0006274 DNA replication termination
GO:0005840 ribosome
GO:0003700 DNA binding transcription factor activity
GO:0004252 serine-type endopeptidase activity
GO:0006525 arginine metabolic process
GO:0006412 translation
GO:0006355 regulation of transcription, DNA-templated
GO:0051304 chromosome separation
GO:0003735 structural constituent of ribosome
GO:0003723 RNA binding
GO:0006508 proteolysis
GO:0005666 DNA-directed RNA polymerase III complex
GO:0005524 ATP binding
GO:0006276 plasmid maintenance

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