phrog_2478 is made of 59 protein sequences and is annotated as "DNA polymerase/primase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
866.39 1027 871


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY087992_p73 APD19201.1 DNA primase KY087992 Mycobacterium phage Mitti Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF140430_p68 ASR87675.1 DNA primase MF140430 Mycobacterium phage Tachez Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF324908_p69 ASR85080.1 DNA primase/polymerase MF324908 Mycobacterium phage Unicorn Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_028979_p73 YP_009215672.1 DNA primase NC_028979 Mycobacterium phage Cheetobro Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_003387_p67 NP_569803.1 hypothetical protein NC_003387 Mycobacterium phage TM4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
KY087993_p67 APD18231.1 DNA primase/polymerase KY087993 Mycobacterium phage Hammy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
KX641264_p67 AOT25085.1 DNA primase/polymerase KX641264 Mycobacterium phage LindNT Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_026598_p72 YP_009125546.1 DNA primase/helicase NC_026598 Mycobacterium phage Milly Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF140398_p67 ASR86348.1 DNA primase/polymerase MF140398 Mycobacterium phage Amohnition Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF324911_p67 ASR85270.1 DNA primase/polymerase MF324911 Mycobacterium phage SirPhilip Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF472892_p69 ASZ75139.1 DNA primase/polymerase MF472892 Mycobacterium phage TreyKay Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
KJ567045_p70 AID59170.1 primase KJ567045 Mycobacterium phage Emerson Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF377440_p68 ASR78000.1 DNA primase/polymerase MF377440 Mycobacterium phage Bella96 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
JF937104_p69 AEK09879.1 DNA primase JF937104 Mycobacterium virus Pixie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
NC_027365_p73 YP_009150938.1 gp74 NC_027365 Mycobacterium virus Fionnbarth Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
KX683428_p66 AOT23805.1 DNA primase/helicase KX683428 Mycobacterium phage TBond007 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MG962364_p68 AVO24822.1 DNA primase/polymerase MG962364 Mycobacterium phage Deby Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF140402_p73 ASW31713.1 DNA primase MF140402 Mycobacterium phage Chancellor Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
KX621007_p72 AOT23193.1 DNA primase KX621007 Mycobacterium phage Taquito Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_028978_p69 YP_009215573.1 DNA primase/helicase NC_028978 Mycobacterium phage Murucutumbu Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
KY945355_p71 ARQ95510.1 primase KY945355 Mycobacterium phage Shandong1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MH001453_p68 AVO22006.1 DNA primase MH001453 Mycobacterium phage Adonis Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF140416_p72 ASR87241.1 DNA primase MF140416 Mycobacterium phage LastHope Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
KX585253_p68 AOQ29127.1 primase KX585253 Mycobacterium phage HedwigODU Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF140406_p67 ASW31814.1 DNA primase/polymerase MF140406 Mycobacterium phage DarthP Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
JN185608_p68 AEJ93820.1 hypothetical protein JN185608 Mycobacterium virus Jaws Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
MF373841_p70 ASR84815.1 DNA primase/helicase MF373841 Mycobacterium phage Hurricane Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MH051258_p72 AVR77386.1 DNA primase MH051258 Mycobacterium phage SamScheppers Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MG962371_p68 AVO25582.1 DNA primase/polymerase MG962371 Mycobacterium phage LaterM Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF140411_p72 ASR86812.1 DNA primase/helicase MF140411 Mycobacterium phage Findley Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF185722_p70 ASR85954.1 DNA primase MF185722 Mycobacterium phage Peanam Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF668267_p70 ASZ72697.1 DNA primase MF668267 Mycobacterium phage Apocalypse Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF919532_p67 ATS92816.1 DNA primase/polymerase MF919532 Mycobacterium phage Sulley Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_026603_p72 YP_009125824.1 DNA primase NC_026603 Mycobacterium phage Keshu Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
KX688047_p72 AOZ64409.1 DNA primase/helicase KX688047 Mycobacterium phage Marcoliusprime Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
JX042579_p72 AFN37760.1 DNA primase JX042579 Mycobacterium virus Macncheese Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
JF704106_p71 AEK08031.1 primase/helicase JF704106 Mycobacterium virus Anaya Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
JF704105_p68 AEJ95838.1 DNA primase JF704105 Mycobacterium phage Adephagia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_030939_p58 YP_009276413.1 hypothetical protein NC_030939 Gordonia phage GMA4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MF140428_p69 ASR87583.1 DNA primase MF140428 Mycobacterium phage Slimphazie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_028759_p72 YP_009195318.1 DNA primase NC_028759 Mycobacterium phage Mufasa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF140435_p73 ASR87781.1 DNA primase MF140435 Mycobacterium phage Wintermute Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
KX657794_p68 AOZ61400.1 DNA primase KX657794 Mycobacterium phage SamuelLPlaqson Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_024147_p71 YP_009032465.1 DNA primase/helicase NC_024147 Mycobacterium phage ZoeJ Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF324915_p67 ASR85668.1 DNA primase/polymerase MF324915 Mycobacterium phage Amgine Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_028846_p71 YP_009202702.1 DNA primase/helicase NC_028846 Mycobacterium phage ShedlockHolmes Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_023498_p73 YP_009002724.1 DNA primase NC_023498 Mycobacterium phage Validus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
AP018469_p71 BBC43359.1 putative DNA primase AP018469 Mycobacterium phage Y10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; Mycobacterium virus Fionnbarth.
NC_023747_p69 YP_009019049.1 gp70 NC_023747 Mycobacterium phage BarrelRoll Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
p416799 no NCBI prot ID no annotation VI_04096 Actinobacteria_gi_485467442 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_028936_p59 YP_009211144.1 DNA primase NC_028936 Mycobacterium phage Enkosi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF324913_p71 ASR85472.1 DNA primase/polymerase MF324913 Mycobacterium phage Cain Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
MF140412_p68 ASR86902.1 DNA primase MF140412 Mycobacterium phage Jeckyll Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_014459_p70 YP_003857043.1 gp71 NC_014459 Mycobacterium virus Crimd Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
MF324912_p71 ASR85371.1 DNA primase/polymerase MF324912 Mycobacterium phage Phrank Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_014458_p67 YP_003856946.1 gp68 NC_014458 Mycobacterium virus Angelica Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus.
MF324914_p72 ASR85572.1 DNA primase/polymerase MF324914 Mycobacterium phage Krueger Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Timquatrovirus; unclassified Timquatrovirus.
NC_005887_p46 YP_024966.1 putative primase/helicase protein NC_005887 Burkholderia virus BcepC6B Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Ryyoungvirus.
NC_025463_p57 YP_009103753.1 DNA primase NC_025463 Shewanella sp. phage 1/44 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1571 95 HNH endonuclease DNA, RNA and nucleotide metabolism 52 2.29E-186 176.76
phrog_3055 47 RusA-like Holliday junction resolvase DNA, RNA and nucleotide metabolism 24 3.18E-86 76.62
phrog_7662 15 no annotation unknown function 15 0 1000
phrog_10480 10 no annotation unknown function 8 6.07E-35 25.34
phrog_24356 3 no annotation unknown function 3 0 1000
phrog_27140 3 no annotation unknown function 3 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10514 DNA primase DNA, RNA and nucleotide metabolism 96.7 1.4E-05 2-323 / 2-271
phrog_1156 DNA primase DNA, RNA and nucleotide metabolism 100.0 1.7E-75 417-861 / 310-784
phrog_16213 DNA primase DNA, RNA and nucleotide metabolism 99.7 9.8E-22 524-855 / 314-653
phrog_16950 DNA primase DNA, RNA and nucleotide metabolism 100.0 1.6E-66 419-837 / 363-809
phrog_1829 DNA primase DNA, RNA and nucleotide metabolism 100.0 2.6E-78 415-863 / 315-764
phrog_1883 DNA helicase DNA, RNA and nucleotide metabolism 100.0 3.3E-60 418-860 / 275-756
phrog_2249 DNA primase DNA, RNA and nucleotide metabolism 97.9 1.4E-08 524-838 / 438-746
phrog_25314 no annotation unknown function 98.2 1.5E-09 6-235 / 9-234
phrog_28894 DNA polymerase/primase DNA, RNA and nucleotide metabolism 100.0 2.4E-54 3-368 / 14-359
phrog_3123 no annotation unknown function 94.5 0.0031 48-226 / 51-179
phrog_36873 DNA helicase DNA, RNA and nucleotide metabolism 95.4 0.00077 4-240 / 11-203
phrog_4210 DNA polymerase DNA, RNA and nucleotide metabolism 95.4 0.00074 544-860 / 120-430
phrog_6088 DNA primase DNA, RNA and nucleotide metabolism 100.0 6.1E-88 422-858 / 347-779
phrog_7601 no annotation unknown function 100.0 1.4E-34 580-862 / 1-279
phrog_864 DNA primase DNA, RNA and nucleotide metabolism 100.0 2.5E-50 517-857 / 162-506

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04735.11 Baculovirus DNA helicase 7.3E-10 576-727 / 883-1031
PF08800.9 VirE N-terminal domain 7.7E-10 70-201 / 8-119
PF06048.10 Domain of unknown function (DUF927) 1.2E-09 558-663 / 146-254
PF16793.4 RepB DNA-primase from phage plasmid 6.8E-09 66-228 / 48-170
PF05272.10 Virulence-associated protein E 1.4E-08 582-726 / 35-177
PF01057.16 Parvovirus non-structural protein NS1 1.8E-05 597-727 / 116-244
PF00519.16 Papillomavirus helicase 3.4E-05 598-727 / 261-383
PF00910.21 RNA helicase 0.00011 602-678 / 1-73
PF08707.10 Primase C terminal 2 (PriCT-2) 0.00069 278-342 / 14-74
PF06431.10 Polyomavirus large T antigen C-terminus 0.0014 599-663 / 155-214
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 0.0073 600-625 / 33-58
PF02257.14 RFX DNA-binding domain 0.0078 783-839 / 2-54

Annotations of the NCBI proteins of this PHROG


25:DNA primase 15:DNA primase/polymerase 10:DNA primase/helicase 3:hypothetical protein 3:primase 1:primase/helicase 1:primase/helicase protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K06919 K06919 : putative DNA primase/helicase no pathways 312 51

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006355 regulation of transcription, DNA-templated
GO:0003678 DNA helicase activity
GO:0003723 RNA binding
GO:0006260 DNA replication
GO:0004003 ATP-dependent DNA helicase activity
GO:0019079 viral genome replication
GO:0005524 ATP binding
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0003677 DNA binding
GO:0003724 RNA helicase activity

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