phrog_2488 is made of 59 protein sequences and is annotated as "DNA helicase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
570.83 938 573


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_005361_p10 NP_963976.1 ORF B494 NC_005361 Sulfolobus virus Kamchatka 1 Viruses; Fuselloviridae; Alphafusellovirus.
p91506 no NCBI prot ID no annotation VI_12481 Thermoprotei_gi_483380609_2368826_2414990 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_013585_p13 YP_003331418.1 Rad3-like helicase NC_013585 Acidianus spindle-shaped virus 1 (SSV1) Viruses; Fuselloviridae; Betafusellovirus.
NC_013588_p12 YP_003331495.1 Rad3-like helicase NC_013588 Sulfolobus spindle-shaped virus 7 (SSV7) Viruses; Fuselloviridae; Alphafusellovirus.
NC_029027_p55 YP_009219954.1 putative DNA repair helicase Rad3 NC_029027 Sulfolobales virus YNP1 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses.
LC168164_p153 BAV39279.1 ATP-dependent helicase LC168164 Tenacibaculum phage pT24 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
NC_028676_p105 YP_009189490.1 putative ATP-dependent helicase NC_028676 Sinorhizobium phage phiM9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
MF403007_p14 ASV44621.1 putative ATP-dependent helicase MF403007 Agrobacterium phage Atu_ph04 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
NC_013697_p69 YP_003358924.1 hypothetical protein NC_013697 Deftia phage phiW-14 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ionavirus; Delftia virus PhiW14.
NC_019521_p232 YP_007006846.1 gp239 NC_019521 Sphingomonas phage PAU Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_025446_p183 YP_009101579.1 DNA helicase NC_025446 Escherichia phage ECML-4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
MG428990_p118 AUG87824.1 ATP-dependent helicase MG428990 Klebsiella phage Menlow Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Klebsiella virus Menlow.
KY914485_p181 ARK08000.1 putative ATP-dependent helicase KY914485 Aeromonas phage phiA8-29 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
MG973030_p85 AVO22928.1 DNA helicase MG973030 Erwinia phage vB_EamM-Bue1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
NC_019530_p85 YP_007008065.1 ATP-dependent helicase NC_019530 Salmonella phage Sh19 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_003345_p21 NP_542515.1 ATP-dependent helicase NC_003345 Halorubrum phage HF2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_015296_p106 YP_004327477.1 ATP-dependent helicase NC_015296 Salmonella phage ViI Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
MG428991_p110 AUG88031.1 ATP-dependent helicase MG428991 Klebsiella phage May Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Klebsiella virus May.
NC_022768_p99 YP_008770926.1 ATP-dependent helicase NC_022768 Salmonella phage Maynard Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
NC_022772_p99 YP_008771717.1 DNA helicase NC_022772 Salmonella phage Marshall Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
MG383452_p69 ATW66827.1 DNA helicase MG383452 Escherichia phage FEC14 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
MG428992_p116 AUG88251.1 ATP-dependent helicase MG428992 Salmonella phage Mutine Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
NC_027119_p60 YP_009140237.1 DNA helicase NC_027119 Salmonella phage Det7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_016570_p97 YP_004957800.1 putative ATP-dependent helicase NC_016570 Escherichia virus CBA120 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_031045_p142 YP_009283915.1 DNA helicase NC_031045 Salmonella phage GG32 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_021320_p92 YP_008058540.1 Rad3-related DNA helicase NC_021320 Halovirus HRTV-5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_019925_p94 YP_007237416.1 putative ATP-dependent DNA helicase NC_019925 Dickeya virus Limestone Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus.
MG770379_p186 AUV59302.1 DNA helicase MG770379 Klebsiella virus vB_KpnM_KpS110 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Klebsiella virus KpS110.
MF001362_p100 ASZ77647.1 ATP-dependent helicase MF001362 Salmonella phage SP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
NC_013693_p112 YP_003358599.1 putative ATP-dependent helicase NC_013693 Shigella phage Ag3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Agtrevirus.
NC_027340_p77 YP_009147589.1 DNA helicase NC_027340 Erwinia phage phiEa2809 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae.
NC_029042_p144 YP_009220888.1 DNA helicase NC_029042 Salmonella phage 38 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_024122_p196 YP_009030518.1 DNA helicase NC_024122 Salmonella phage vB_SalM_SJ3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_022343_p150 YP_008532101.1 ATP-dependent helicase NC_022343 Klebsiella phage 0507-KN2-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus.
NC_025429_p76 YP_009099815.1 putative ATP-dependent helicase NC_025429 Rhizobium phage vB_RleM_P10VF Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
NC_004927_p19 NP_861607.1 ATP-dependent helicase NC_004927 Halovirus HF1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_019910_p65 YP_007236160.1 DNA helicase NC_019910 Salmonella phage SKML-39 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Agtrevirus.
NC_020083_p105 YP_007349084.1 ATP-dependent helicase NC_020083 Serratia phage phiMAM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae.
NC_016073_p100 YP_004895271.1 ATP-dependent helicase NC_016073 Salmonella phage SFP10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
KM209228_p91 AIM51330.1 type III restriction enzyme res subunit KM209228 Dickeya phage phiD3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; Dickeya virus Limestone.
NC_023856_p21 YP_009021267.1 ATP-dependent helicase NC_023856 Salmonella phage vB_SalM_SJ2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
MF285619_p115 ASZ78881.1 ATP-dependent helicase MF285619 Serratia phage 2050H1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
NC_025452_p59 YP_009102899.1 type III restriction enzyme, res subunit NC_025452 Dickeya phage RC-2014 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus.
KY942057_p91 ASD51477.1 putative ATP-dependent DNA helicase KY942057 Dickeya phage XF4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
MG266157_p92 ATW62096.1 putative ATP-dependent DNA helicase MG266157 Dickeya phage PP35 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
NC_021321_p98 YP_008058664.1 Rad3-related DNA helicase NC_021321 Halovirus HRTV-8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_019452_p103 YP_007002743.1 putative ATP-dependent helicase NC_019452 Escherichia phage PhaxI Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
KY787213_p150 ARM69987.1 ATP-dependent helicase KY787213 Salmonella phage BSP101 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
KX171211_p58 ANT44517.1 DNA helicase KX171211 Salmonella phage vB_SenM-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
AP018399_p312 BBA65460.1 ATP-dependent helicase AP018399 Xanthomonas phage XacN1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
LC373201_p84 BBD52264.1 putative ATP-dependent DNA helicase LC373201 Enterobacter phage phiEM4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Agtrevirus; unclassified Agtrevirus.
KY942056_p91 ASD51278.1 putative ATP-dependent DNA helicase KY942056 Dickeya phage JA15 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
NC_023719_p73 YP_009015384.1 gp73 NC_023719 Bacillus virus G Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
KX147096_p166 ANM47275.1 DNA helicase KX147096 Serratia phage vB_Sru_IME250 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Serratia virus IME250.
KY630163_p10 ARB06296.1 DNA helicase KY630163 Salmonella phage S8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
NC_031128_p49 YP_009293297.1 DNA helicase NC_031128 Salmonella phage vB_SalM_PM10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
MH019216_p36 AVP41475.1 DNA helicase MH019216 Streptomyces phage Wentworth Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_031245_p158 YP_009302545.1 ATP-dependent helicase NC_031245 Bacillus phage SP-15 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Thornevirus; Bacillus virus SP15.
MH019215_p33 AVP41367.1 DNA helicase MH019215 Streptomyces phage Yara Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_379 331 DNA binding protein DNA, RNA and nucleotide metabolism 36 1.33E-106 97.0
phrog_15266 6 no annotation unknown function 4 2.41E-20 10.74
phrog_21681 4 no annotation unknown function 2 2.41E-12 2.74
phrog_31784 2 no annotation unknown function 2 0 1000
phrog_20310 4 no annotation unknown function 2 2.41E-12 2.74

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10691 no annotation unknown function 92.8 0.015 25-206 / 319-453
phrog_16128 no annotation unknown function 96.7 1.6E-05 345-553 / 281-475
phrog_16259 DNA helicase DNA, RNA and nucleotide metabolism 97.7 5.2E-08 30-209 / 109-238
phrog_16694 no annotation unknown function 97.4 5.1E-07 25-112 / 262-343
phrog_16 DNA helicase DNA, RNA and nucleotide metabolism 98.8 3.9E-12 420-553 / 205-318
phrog_170 PhoH-like phosphate starvation-inducible other 91.0 0.043 28-76 / 25-70
phrog_28699 no annotation unknown function 98.6 5.3E-11 516-562 / 41-89
phrog_325 Dda-like helicase DNA, RNA and nucleotide metabolism 93.9 0.0059 35-103 / 5-65
phrog_3830 no annotation unknown function 91.6 0.032 37-114 / 273-352
phrog_50 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 90.5 0.054 54-83 / 109-138
phrog_62 DNA helicase DNA, RNA and nucleotide metabolism 95.8 0.00028 416-554 / 312-428
phrog_6819 Holliday junction branch migration helicase DNA, RNA and nucleotide metabolism 98.7 1.4E-11 348-548 / 169-354
phrog_9690 DNA helicase DNA, RNA and nucleotide metabolism 92.7 0.017 420-546 / 156-264

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF06862.11 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 2.2E-22 482-612 / 358-467
PF02399.14 Origin of replication binding protein 2.4E-19 482-611 / 282-388
PF00176.22 SNF2 family N-terminal domain 2.5E-13 76-280 / 1-209
PF13872.5 P-loop containing NTP hydrolase pore-1 1.4E-11 72-143 / 35-112
PF07517.13 SecA DEAD-like domain 1.3E-10 71-242 / 89-226
PF00271.30 Helicase conserved C-terminal domain 1.7E-10 481-601 / 16-118
PF14617.5 U3-containing 90S pre-ribosomal complex subunit 4.1E-10 69-239 / 61-205
PF16203.4 ERCC3/RAD25/XPB C-terminal helicase 8.7E-10 482-604 / 60-156
PF00270.28 DEAD/DEAH box helicase 2.1E-09 75-143 / 2-68
PF07652.13 Flavivirus DEAD domain 6.8E-09 90-143 / 2-56
PF12340.7 Protein of unknown function (DUF3638) 1.1E-08 73-143 / 23-88
PF13086.5 AAA domain 1.8E-08 73-142 / 2-69
PF02562.15 PhoH-like protein 2.4E-08 72-135 / 4-64
PF13871.5 C-terminal domain on Strawberry notch homologue 1.8E-07 506-602 / 23-114
PF04851.14 Type III restriction enzyme, res subunit 2.8E-07 73-142 / 4-73
PF11496.7 Class II histone deacetylase complex subunits 2 and 3 8E-07 482-604 / 104-203
PF00580.20 UvrD/REP helicase N-terminal domain 2.1E-06 74-143 / 2-68
PF13307.5 Helicase C-terminal domain 1.8E-05 482-564 / 8-101
PF04466.12 Phage terminase large subunit 0.00016 93-143 / 2-57
PF05127.13 Helicase 0.00024 96-139 / 1-46
PF13604.5 AAA domain 0.00025 73-112 / 2-36
PF13245.5 AAA domain 0.0016 90-135 / 9-54

Annotations of the NCBI proteins of this PHROG


25:ATP-dependent helicase 17:DNA helicase 5:ATP-dependent DNA helicase 4:hypothetical protein 2:Rad3-related DNA helicase 2:Rad3-like helicase 1:DNA repair helicase Rad3 1:type III restriction enzyme res subunit 1:type III restriction enzyme, res subunit

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K03722 dinG : ATP-dependent DNA helicase DinG [EC:3.6.4.12] no pathways 397 3

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0006139 nucleobase-containing compound metabolic process
GO:0016020 membrane
GO:0017038 protein import
GO:0008026 ATP-dependent helicase activity
GO:0003677 DNA binding
GO:0006260 DNA replication
GO:0003676 nucleic acid binding
GO:0016787 hydrolase activity
GO:0016575 histone deacetylation
GO:0003688 DNA replication origin binding
GO:0070823 HDA1 complex

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