phrog_2506 is made of 58 protein sequences and is annotated as "exonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
429.29 750 587


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KJ595575_p183 AID18263.1 HNH endonuclease domain protein KJ595575 Mycobacterium phage Willis Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
KT365400_p177 ALF51273.1 hypothetical protein KT365400 Mycobacterium phage ErnieJ Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
JF704096_p182 AEJ94943.1 hypothetical protein JF704096 Mycobacterium phage Ghost Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
KX781992_p183 AOZ63537.1 HNH endonuclease KX781992 Mycobacterium phage Gabriel Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
KX831080_p172 APD17214.1 hypothetical protein KX831080 Mycobacterium phage Lukilu Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Lukilu.
MF919527_p178 ATN91460.1 exonuclease MF919527 Mycobacterium phage Phox Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
JF704116_p181 AEK06973.1 hypothetical protein JF704116 Mycobacterium phage Drazdys Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
JQ911768_p183 AFL46870.1 HNH endonuclease domain protein JQ911768 Mycobacterium phage Ava3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
NC_004687_p179 NP_818255.1 gp204 NC_004687 Mycobacterium phage Bxz1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
NC_023725_p185 YP_009016646.1 gp215 NC_023725 Mycobacterium phage Nappy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
NC_023733_p181 YP_009017516.1 gp212 NC_023733 Mycobacterium phage MoMoMixon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
MF919495_p187 ATN87860.1 exonuclease MF919495 Mycobacterium phage Bigswole Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
KX369583_p184 ANT41719.1 homing endonuclease KX369583 Mycobacterium phage Littleton Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
MF919499_p186 ATN88397.1 HNH endonuclease MF919499 Mycobacterium phage Daffodil Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
JN204348_p181 AEK06658.1 hypothetical protein JN204348 Mycobacterium phage Sebata Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Sebata.
MG812493_p186 AVJ48461.1 hypothetical protein MG812493 Mycobacterium phage NuevoMundo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
JN699625_p179 AER25547.1 homing-endonuclease JN699625 Mycobacterium phage Wally Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
NC_011269_p174 YP_002224207.1 gp208 NC_011269 Mycobacterium phage ScottMcG Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
MH051260_p187 AVR77687.1 hypothetical protein MH051260 Mycobacterium phage InterFolia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
NC_021348_p185 YP_008061443.1 HNH endonuclease domain protein NC_021348 Mycobacterium phage ArcherS7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
KT321476_p182 AKY02476.1 HNH endonuclease domain protein KT321476 Mycobacterium phage Zeenon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
MG872839_p180 AVI04783.1 LAGLIDADG endonuclease MG872839 Mycobacterium phage LifeSavor Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
GQ303262_p175 ACU41702.1 hypothetical protein GQ303262 Mycobacterium phage LRRHood Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
MG812494_p184 AVJ48692.1 hypothetical protein MG812494 Mycobacterium phage Pier Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
NC_023696_p189 YP_009012967.1 gp222 NC_023696 Mycobacterium phage Dandelion Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
KT365398_p184 ALF51047.1 homing endonuclease KT365398 Mycobacterium phage DTDevon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
NC_023737_p185 YP_009017958.1 gp218 NC_023737 Mycobacterium phage Pleione Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
MH051266_p184 AVR57408.1 endonuclease MH051266 Mycobacterium phage MikeLiesIn Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
NC_021349_p179 YP_008061674.1 HNH endonuclease domain protein NC_021349 Mycobacterium phage Astraea Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
NC_023714_p179 YP_009014773.1 gp213 NC_023714 Mycobacterium phage LinStu Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
MH051261_p181 AVR77904.1 HNH endonuclease domain protein MH051261 Mycobacterium phage Tyke Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
NC_008207_p173 YP_656186.1 gp206 NC_008207 Mycobacterium phage Catera Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
KX721255_p180 AOZ63065.1 HNH endonuclease KX721255 Mycobacterium phage Yucca Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
NC_028986_p174 YP_009216438.1 gp201 NC_028986 Mycobacterium phage Alice Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
NC_011271_p175 YP_002224651.1 gp207 NC_011271 Mycobacterium phage Cali Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
KX721256_p181 AOZ63304.1 HNH endonuclease KX721256 Mycobacterium phage Erdmann Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
NC_013650_p170 YP_003347852.1 gp202 NC_013650 Mycobacterium phage ET08 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
NC_021346_p189 YP_008060986.1 HNH endonuclease domain protein NC_021346 Mycobacterium phage Gizmo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
MF919494_p173 ATN87631.1 exonuclease MF919494 Mycobacterium phage BeanWater Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
NC_011272_p173 YP_002224871.1 gp206 NC_011272 Mycobacterium phage Rizal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
JN699013_p188 AER49702.1 hypothetical protein JN699013 Mycobacterium phage Pio Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
KF024734_p185 AGV99905.1 HNH endonuclease domain protein KF024734 Mycobacterium phage Shrimp Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; Mycobacterium virus Bxz1.
NC_028869_p175 YP_009204740.1 Cas4-like exonuclease NC_028869 Mycobacterium phage HyRo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
NC_011270_p175 YP_002224429.1 gp208 NC_011270 Mycobacterium phage Spud Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
NC_031080_p205 YP_009288069.1 exonuclease NC_031080 Mycobacterium phage Tonenili Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
NC_029044_p183 YP_009221313.1 hypothetical protein NC_029044 Mycobacterium phage Breeniome Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus.
MF919513_p179 ATN90143.1 HNH endonuclease MF919513 Mycobacterium phage Koguma Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bixzunavirus; unclassified Bixzunavirus.
NC_011273_p157 YP_002225075.1 gp196 NC_011273 Mycobacterium phage Myrna Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
MF668280_p171 ASZ74746.1 exonuclease MF668280 Mycobacterium phage Phabba Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
MG962366_p81 AVO25015.1 exonuclease MG962366 Rhodococcus phage Finch Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
NC_021347_p165 YP_008061203.1 hypothetical protein NC_021347 Rhodococcus phage E3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_023502_p72 YP_009003229.1 hypothetical protein NC_023502 Rhizobium phage vB_RleS_L338C Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KU245542_p48 ALT58040.1 hypothetical protein KU245542 Pseudomonas phage SM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Samunavirus; Pseudomonas virus SM1.
MG189906_p63 ATS92304.1 hypothetical protein MG189906 Stenotrophomonas phage vB_SmaS_DLP_5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Delepquintavirus; Stenotrophomonas virus DLP5.
MG720309_p42 AUR81124.1 hypothetical protein MG720309 Vibrio phage Ares1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
JF713456_p84 AEH21897.1 VHS1084 protein JF713456 Vibrio phage 1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_016567_p76 YP_004957569.1 hypothetical protein NC_016567 Vibrio phage SIO-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KX925554_p67 APC46329.1 hypothetical protein KX925554 Streptomyces phage BRock Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_140 680 RusA-like Holliday junction resolvase DNA, RNA and nucleotide metabolism 47 2.76E-118 108.68
phrog_3038 47 no annotation unknown function 47 0 1000
phrog_2002 76 Holliday junction resolvase DNA, RNA and nucleotide metabolism 10 5.69E-31 21.37
phrog_159 617 RuvC-like Holliday junction resolvase DNA, RNA and nucleotide metabolism 7 2.78E-14 4.68
phrog_37480 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_149 exonuclease DNA, RNA and nucleotide metabolism 91.5 0.033 123-235 / 109-201
phrog_1674 exonuclease DNA, RNA and nucleotide metabolism 94.4 0.0035 49-247 / 50-246
phrog_1706 CRISPR/Cas system associated DNA, RNA and nucleotide metabolism 99.5 4.5E-18 48-276 / 26-227
phrog_1990 Cas4-domain exonuclease DNA, RNA and nucleotide metabolism 98.7 1.4E-11 49-275 / 28-235
phrog_2139 exonuclease DNA, RNA and nucleotide metabolism 92.9 0.014 48-214 / 19-196
phrog_434 RecE-like recombination exonuclease DNA, RNA and nucleotide metabolism 96.7 1.4E-05 86-250 / 52-193

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01771.16 Herpesvirus alkaline exonuclease 2.5E-11 43-295 / 90-294
PF01930.16 Domain of unknown function DUF83 6.7E-11 97-322 / 1-160
PF09810.8 Exonuclease V - a 5' deoxyribonuclease 1.1E-10 93-149 / 11-60
PF12705.6 PD-(D/E)XK nuclease superfamily 2.1E-10 187-321 / 130-243
PF10926.7 Protein of unknown function (DUF2800) 3.1E-10 95-325 / 3-231
PF09588.9 YqaJ-like viral recombinase domain 2.1E-09 91-251 / 5-139
PF06023.11 CRISPR-associated exonuclease Csa1 2.1E-09 92-321 / 44-281
PF12684.6 PDDEXK-like domain of unknown function (DUF3799) 2.3E-08 185-251 / 105-165
PF13366.5 PD-(D/E)XK nuclease superfamily 0.00069 184-262 / 52-107

Annotations of the NCBI proteins of this PHROG


28:hypothetical protein 8:HNH endonuclease domain protein 6:exonuclease 5:HNH endonuclease 3:protein of an unannotated phage 2:homing endonuclease 1:HNH endonuclease domain 1:LAGLIDADG endonuclease 1:homing-endonuclease 1:prolipoprotein diacylglyceryl transferase 1:endonuclease 1:Cas4-like exonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K02314 dnaB : replicative DNA helicase [EC:3.6.4.12] ko03030 DNA replication
ko04112 Cell cycle - Caulobacter
214 29

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity

Loading in process