phrog_25184 is made of 3 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
207.33 210 209


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF787246_p60 ATG86367.1 HNH endonuclease MF787246 Lactobacillus phage LpeD Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; unclassified Herelleviridae.
MG765277_p131 AUV60016.1 hypothetical protein MG765277 Lactobacillus phage Bacchae Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Twortvirinae; Harbinvirus; Lactobacillus virus Bacchae.
MG765279_p47 AUV60112.1 hypothetical protein MG765279 Lactobacillus phage Semele Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Twortvirinae; Harbinvirus; Lactobacillus virus Semele.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_11757 9 no annotation unknown function 3 6.91E-20 10.28
phrog_21010 4 no annotation unknown function 2 6.58E-16 6.3
phrog_22973 3 glycosyltransferase moron, auxiliary metabolic gene and host takeover 1 1.11E-10 1.08

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 94.9 0.0017 74-160 / 84-153
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 90.9 0.044 89-161 / 146-201
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.2E-06 122-162 / 26-66
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 7E-05 88-162 / 61-115
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 97.9 1.3E-08 81-162 / 71-132
phrog_16986 no annotation unknown function 96.5 3.6E-05 80-163 / 10-71
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00012 126-192 / 29-105
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 98.7 5.9E-12 124-170 / 44-89
phrog_2323 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0046 82-157 / 17-86
phrog_23285 HNH endonuclease DNA, RNA and nucleotide metabolism 97.6 1.3E-07 80-168 / 39-132
phrog_25420 HNH endonuclease DNA, RNA and nucleotide metabolism 93.3 0.011 90-159 / 45-106
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 95.2 0.0011 125-167 / 34-82
phrog_32453 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0042 128-173 / 85-132
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 8E-05 86-166 / 25-89
phrog_36777 no annotation unknown function 92.6 0.018 128-161 / 5-44
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 7.8E-05 87-161 / 21-72
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 96.4 4.1E-05 88-158 / 49-97
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 94.3 0.0041 127-157 / 22-54
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 97.0 3.3E-06 90-160 / 6-54
phrog_655 homing endonuclease DNA, RNA and nucleotide metabolism 92.6 0.018 129-148 / 25-44
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0054 130-157 / 56-83
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 93.3 0.011 127-173 / 79-127
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 6.3E-06 69-159 / 91-154
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00037 123-172 / 130-180
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 91.5 0.033 127-159 / 42-74

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13395.5 HNH endonuclease 1.1E-06 126-160 / 17-51
PF05766.11 Bacteriophage Lambda NinG protein 1.3E-06 71-161 / 67-137
PF01844.22 HNH endonuclease 3.2E-06 127-159 / 12-47
PF05315.10 ICEA Protein 3.6E-06 77-159 / 80-149
PF14279.5 HNH endonuclease 7.5E-06 126-160 / 12-45
PF13391.5 HNH endonuclease 2.9E-05 127-160 / 12-45
PF06147.10 Protein of unknown function (DUF968) 0.00012 127-160 / 138-174
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 0.00057 127-161 / 264-297
PF16784.4 Putative HNHc nuclease 0.0052 128-160 / 134-171

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 1:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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