phrog_25420 is made of 3 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
299.67 310 305


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY630187_p529 AQW89054.1 HNH endonuclease KY630187 Serratia phage BF Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Eneladusvirus; Serratia virus BF.
KU574722_p535 AMM44098.1 hypothetical protein KU574722 Pectobacterium phage CBB Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Mimasvirus; Pectinobacterium virus CBB.
NC_019401_p533 YP_006987635.1 hypothetical protein NC_019401 Cronobacter phage vB_CsaM_GAP32 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Mimasvirus; Cronobacter virus GAP32.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_27158 3 virion structural protein head and packaging 2 8.23E-17 7.21
phrog_1250 120 unknown function unknown function 2 2.31E-11 1.76

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 94.4 0.0035 38-102 / 10-59
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 97.0 4.1E-06 37-112 / 73-135
phrog_16986 no annotation unknown function 92.3 0.021 22-108 / 6-69
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 92.6 0.018 38-108 / 10-75
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.00024 42-121 / 33-89
phrog_23285 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.7E-06 71-148 / 88-157
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 94.4 0.0035 45-106 / 90-159
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 99.4 1.9E-16 46-167 / 12-134
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 94.5 0.0031 40-110 / 24-86
phrog_35175 HNH endonuclease DNA, RNA and nucleotide metabolism 99.8 1.4E-23 7-173 / 10-173
phrog_4581 terminase small subunit head and packaging 90.8 0.046 39-107 / 57-108
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 7.9E-05 38-108 / 17-72
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 94.6 0.0028 42-107 / 3-54
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.0002 37-108 / 103-156

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13395.5 HNH endonuclease 4.2E-07 73-107 / 17-51
PF05315.10 ICEA Protein 6.4E-07 32-107 / 81-150
PF05766.11 Bacteriophage Lambda NinG protein 1.3E-06 30-108 / 72-137
PF01844.22 HNH endonuclease 1.6E-06 74-106 / 12-47
PF14279.5 HNH endonuclease 2.7E-06 47-109 / 1-47
PF13391.5 HNH endonuclease 2.2E-05 73-107 / 11-45
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 8E-05 73-109 / 263-298
PF06147.10 Protein of unknown function (DUF968) 0.00021 43-107 / 126-174

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 1:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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