phrog_2562 is made of 57 protein sequences and is annotated as "replication initiation protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
298.95 549 293


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p118839 no NCBI prot ID no annotation VI_00500 Bacilli_gi_500982710 Viruses.
GQ478087_p24 ACZ64107.1 recombinase GQ478087 Enterococcus phage phiFL3B Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phifelvirus; Enterococcus virus FL3.
GQ478082_p18 ACZ63778.1 recombinase GQ478082 Enterococcus phage phiFL1B Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phifelvirus; Enterococcus virus FL1.
p363146 no NCBI prot ID no annotation VI_05182 Bacilli_gi_518727744 Viruses.
p140087 no NCBI prot ID no annotation VI_00481 Bacilli_gi_500219249_340805_382586 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_013646_p18 YP_003347475.1 recombinase NC_013646 Enterococcus phage phiFL1A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phifelvirus.
NC_013648_p20 YP_003347582.1 recombinase NC_013648 Enterococcus phage phiFL3A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phifelvirus.
p118779 no NCBI prot ID no annotation VI_00511 Bacilli_gi_501001074 Viruses.
p388229 no NCBI prot ID no annotation VI_05164 Bacilli_gi_511664302 Viruses.
p177910 no NCBI prot ID no annotation VI_00920 Bacilli_gi_522835552 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p177887 no NCBI prot ID no annotation VI_00920 Bacilli_gi_522835552 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_028783_p45 YP_009197564.1 DnaD domain-containing protein NC_028783 Lactobacillus phage iLp84 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p385291 no NCBI prot ID no annotation VI_05163 Bacilli_gi_511662431 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p247590 no NCBI prot ID no annotation VI_05174 Bacilli_gi_511746432 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p434401 no NCBI prot ID no annotation VI_05186 Bacilli_gi_511748074 Viruses.
p434426 no NCBI prot ID no annotation VI_05168 Bacilli_gi_511666795 Viruses.
NC_017732_p16 YP_006218711.1 dD and phage-associated domain protein NC_017732 Enterococcus phage EF62phi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
p321183 no NCBI prot ID no annotation VI_00672 Bacilli_gi_505752071 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p258628 no NCBI prot ID no annotation VI_00589 Bacilli_gi_502198097 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p280133 no NCBI prot ID no annotation VI_00582 Bacilli_gi_501975299 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p262444 no NCBI prot ID no annotation VI_00809 Bacilli_gi_242364200 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p282555 no NCBI prot ID no annotation VI_00606 Bacilli_gi_502402921 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p263832 no NCBI prot ID no annotation VI_00587 Bacilli_gi_502174949 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p270461 no NCBI prot ID no annotation VI_00588 Bacilli_gi_502190608 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p331601 no NCBI prot ID no annotation VI_00558 Bacilli_gi_501569203 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p396343 no NCBI prot ID no annotation VI_00942 Bacilli_gi_522837238 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p325772 no NCBI prot ID no annotation VI_00659 Bacilli_gi_505741126 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p325109 no NCBI prot ID no annotation VI_00651 Bacilli_gi_505733771 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p272639 no NCBI prot ID no annotation VI_00814 Bacilli_gi_242361992 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p166245 no NCBI prot ID no annotation VI_12298 Negativicutes_gi_303229258 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p150305 no NCBI prot ID no annotation VI_12301 Negativicutes_gi_416999523 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p167281 no NCBI prot ID no annotation VI_04008 Negativicutes_gi_294791573_831244_870566 Viruses.
p142758 no NCBI prot ID no annotation VI_06210 Clostridia_gi_397904599_10862_52431 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p239383 no NCBI prot ID no annotation VI_01298 Clostridia_gi_331268188_1296309_1329168 Viruses.
p212394 no NCBI prot ID no annotation VI_05780 Clostridia_gi_485044578 Viruses.
p219140 no NCBI prot ID no annotation VI_05746 Clostridia_gi_153883175_95370_130282 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p77353 no NCBI prot ID no annotation VI_04384 Bacilli_gi_300765818 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae; Listeria phage B054.
NC_009813_p52 YP_001468756.1 gp52 NC_009813 Listeria phage B054 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p257513 no NCBI prot ID no annotation VI_01243 Clostridia_gi_547807793_174268_205484 Viruses.
p54384 no NCBI prot ID no annotation VI_01307 Clostridia_gi_485075759_38224_92961 Viruses.
p53488 no NCBI prot ID no annotation VI_01191 Clostridia_gi_336440810_359795_415074 Viruses.
p301638 no NCBI prot ID no annotation VI_01259 Clostridia_gi_547873663_11997_37723 Viruses.
p301598 no NCBI prot ID no annotation VI_04015 Negativicutes_gi_546349318_12163_37890 Viruses.
p236199 no NCBI prot ID no annotation VI_01303 Clostridia_gi_483984762 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p354458 no NCBI prot ID no annotation VI_12318 Negativicutes_gi_553308188_0_19186 Viruses.
p157707 no NCBI prot ID no annotation VI_00842 Bacilli_gi_389853198_779839_819962 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p157645 no NCBI prot ID no annotation VI_00774 Bacilli_gi_125622882_779007_819130 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_002667_p16 NP_076650.1 replication protein NC_002667 Lactococcus phage bIL286 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p124372 no NCBI prot ID no annotation VI_00997 Bacilli_gi_15671982_1414087_1456974 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Lactococcus phage bIL286.
p116608 no NCBI prot ID no annotation VI_01254 Clostridia_gi_547857777 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p164726 no NCBI prot ID no annotation VI_05431 Bacilli_gi_566131765_19584_59097 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_028782_p38 YP_009197507.1 DNA replication protein NC_028782 Bacillus phage Pavlov Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus; unclassified Pagevirus.
GQ478085_p21 ACZ63981.1 recombinase GQ478085 Enterococcus phage phiFL2B Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phifelvirus; Enterococcus virus FL2.
NC_013643_p20 YP_003347311.1 recombinase NC_013643 Enterococcus phage phiFL2A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Phifelvirus.
NC_027990_p29 YP_009168559.1 putative replication initiation protein NC_027990 Lactobacillus phage LBR48 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Anamdongvirus; Lactobacillus virus LBR48.
p15378 no NCBI prot ID no annotation VI_01194 Clostridia_gi_373121103_353147_435681 Viruses.
p202446 no NCBI prot ID no annotation VI_06186 Clostridia_gi_553309842_50785_87214 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_50 1303 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 34 6.57E-71 61.3
phrog_148 643 RecT-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 10 1.37E-20 10.99
phrog_4960 27 no annotation unknown function 8 2.84E-29 19.67
phrog_1227 122 exonuclease DNA, RNA and nucleotide metabolism 8 7.32E-23 13.26
phrog_44 1487 single strand DNA binding protein DNA, RNA and nucleotide metabolism 7 2.57E-11 1.71
phrog_715 198 MazG-like pyrophosphatase other 4 7.05E-11 1.27
phrog_23302 3 no annotation unknown function 3 0 1000
phrog_11379 9 no annotation unknown function 3 3.07E-14 4.63
phrog_15077 6 no annotation unknown function 2 3.96E-11 1.52
phrog_29533 2 no annotation unknown function 2 0 1000
phrog_36288 2 no annotation unknown function 2 0 1000
phrog_25488 3 no annotation unknown function 2 1.98E-12 2.83
phrog_16706 5 replisome organizer DNA, RNA and nucleotide metabolism 2 1.98E-11 1.83

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_13390 no annotation unknown function 92.3 0.022 189-263 / 29-101
phrog_16706 replisome organizer DNA, RNA and nucleotide metabolism 99.9 5.4E-27 1-88 / 1-88
phrog_186 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 97.7 6.1E-08 8-289 / 4-258
phrog_19120 no annotation unknown function 95.2 0.00099 223-262 / 1-40
phrog_20437 DNA replication initiation DNA, RNA and nucleotide metabolism 100.0 6.9E-47 1-158 / 1-156
phrog_20981 no annotation unknown function 99.6 7E-19 10-129 / 2-123
phrog_24189 no annotation unknown function 97.2 1.7E-06 9-128 / 16-141
phrog_25071 no annotation unknown function 98.9 1.5E-12 223-292 / 10-85
phrog_29927 replication initiation protein DNA, RNA and nucleotide metabolism 96.7 1.7E-05 189-263 / 31-105
phrog_345 replication initiation O-like DNA, RNA and nucleotide metabolism 90.0 0.064 3-93 / 16-108
phrog_38715 no annotation unknown function 96.5 3.2E-05 9-131 / 3-121
phrog_4016 replication initiation protein DNA, RNA and nucleotide metabolism 97.5 3.4E-07 196-292 / 10-106
phrog_6251 replisome organizer DnaA-like DNA, RNA and nucleotide metabolism 95.8 0.00026 15-261 / 8-278
phrog_6493 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 95.3 0.00079 192-263 / 152-224

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF14297.5 Domain of unknown function (DUF4373) 5.8E-13 16-107 / 1-92
PF03819.16 MazG nucleotide pyrophosphohydrolase domain 1.3E-10 347-414 / 3-76
PF12643.6 MazG-like family 3.3E-08 353-414 / 2-70
PF01503.16 Phosphoribosyl-ATP pyrophosphohydrolase 7.2E-08 347-405 / 23-78
PF09681.9 N-terminal phage replisome organiser (Phage_rep_org_N) 8.9E-06 16-96 / 1-86
PF07261.10 Replication initiation and membrane attachment 1.5E-05 217-271 / 11-65
PF06970.10 Replication initiator protein A (RepA) N-terminus 4.7E-05 16-87 / 2-75
PF08761.10 dUTPase 0.0018 347-397 / 28-87

Annotations of the NCBI proteins of this PHROG


6:recombinase 1:hypothetical protein 1:DnaD domain-containing protein 1:replication protein 1:dD and phage-associated domain protein 1:replication initiation protein 1:DNA replication protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0009143 nucleoside triphosphate catabolic process
GO:0047429 nucleoside-triphosphate diphosphatase activity

Loading in process