phrog_25777 is made of 3 protein sequences and is annotated as "DNA primase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
908.33 936 907


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_025458_p2 YP_009103266.1 DNA primase NC_025458 Shewanella sp. phage 1/41 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
MG675557_p59 AUG84978.1 hypothetical protein MG675557 Pseudoalteromonas phage Maelstrom Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
NC_021563_p14 YP_008130298.1 putative DNA primase NC_021563 Serratia phage Eta Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_16803 5 no annotation unknown function 3 2.74E-21 11.68

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10514 DNA primase DNA, RNA and nucleotide metabolism 91.3 0.037 48-151 / 235-330
phrog_1139 DNA primase DNA, RNA and nucleotide metabolism 98.8 3.5E-12 68-343 / 27-273
phrog_21295 no annotation unknown function 93.2 0.011 50-99 / 235-274
phrog_2249 DNA primase DNA, RNA and nucleotide metabolism 100.0 1.1E-35 68-353 / 15-324
phrog_239 DNA primase/helicase DNA, RNA and nucleotide metabolism 96.3 6E-05 199-319 / 102-226
phrog_3022 DNA primase DNA, RNA and nucleotide metabolism 99.8 5.3E-23 411-899 / 327-752
phrog_33132 DNA primase DNA, RNA and nucleotide metabolism 99.6 7.1E-20 418-885 / 18-433
phrog_35358 DNA primase DNA, RNA and nucleotide metabolism 98.5 1.5E-10 146-343 / 86-286
phrog_47 DNA primase DNA, RNA and nucleotide metabolism 97.4 3.7E-07 52-299 / 1-240
phrog_4913 replication DNA, RNA and nucleotide metabolism 97.7 7E-08 164-346 / 179-388
phrog_510 DNA primase DNA, RNA and nucleotide metabolism 99.9 1.1E-31 45-341 / 4-308
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 90.5 0.054 476-606 / 42-174
phrog_599 Lar-like restriction alleviation protein moron, auxiliary metabolic gene and host takeover 93.2 0.011 67-103 / 9-48

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00493.22 MCM2/3/5 family 1.3E-11 426-811 / 11-320
PF01807.19 CHC2 zinc finger 5.3E-08 53-126 / 14-86
PF12965.6 Domain of unknown function (DUF3854) 5.8E-08 244-343 / 9-125
PF13155.5 Toprim-like 1.6E-07 248-338 / 1-87
PF13148.5 Protein of unknown function (DUF3987) 1.9E-07 637-813 / 203-360
PF13362.5 Toprim domain 8.5E-07 246-340 / 1-88
PF13337.5 Putative ATP-dependent Lon protease 1.5E-06 766-812 / 391-435
PF06431.10 Polyomavirus large T antigen C-terminus 5.9E-06 474-539 / 155-217
PF00519.16 Papillomavirus helicase 3.4E-05 474-537 / 262-320
PF05272.10 Virulence-associated protein E 3.4E-05 473-538 / 58-117
PF01078.20 Magnesium chelatase, subunit ChlI 6.6E-05 475-500 / 23-48
PF07726.10 ATPase family associated with various cellular activities (AAA) 7.4E-05 476-501 / 1-26
PF13662.5 Toprim domain 0.00011 246-313 / 2-81
PF07728.13 AAA domain (dynein-related subfamily) 0.00013 476-501 / 1-26
PF13654.5 AAA domain 0.0037 474-500 / 24-50
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.00026 477-501 / 1-25
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 0.00029 474-539 / 45-111
PF12780.6 P-loop containing dynein motor region D4 0.00043 474-505 / 31-61
PF01751.21 Toprim domain 0.00046 247-313 / 2-74
PF00910.21 RNA helicase 0.0005 477-537 / 1-58
PF08275.10 DNA primase catalytic core, N-terminal domain 0.00069 170-229 / 10-102
PF03969.15 AFG1-like ATPase 0.0013 474-499 / 67-92
PF13177.5 DNA polymerase III, delta subunit 0.0014 475-499 / 20-44
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 0.0014 474-539 / 32-99
PF00158.25 Sigma-54 interaction domain 0.002 474-499 / 22-47
PF04735.11 Baculovirus DNA helicase 0.0024 474-501 / 906-933
PF06048.10 Domain of unknown function (DUF927) 0.0027 474-536 / 188-254
PF14532.5 Sigma-54 interaction domain 0.0028 475-539 / 22-82
PF08298.10 PrkA AAA domain 0.0031 474-499 / 85-110
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.0034 474-499 / 4-29
PF01057.16 Parvovirus non-structural protein NS1 0.0036 474-500 / 118-144
PF00308.17 Bacterial dnaA protein 0.004 475-499 / 34-58
PF01695.16 IstB-like ATP binding protein 0.005 475-499 / 49-73
PF07931.11 Chloramphenicol phosphotransferase-like protein 0.0058 476-501 / 3-28
PF05673.12 Protein of unknown function (DUF815) 0.0064 474-499 / 54-79
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.0066 477-499 / 1-23
PF00625.20 Guanylate kinase 0.0068 475-501 / 3-29
PF12775.6 P-loop containing dynein motor region D3 0.007 475-500 / 34-59

Annotations of the NCBI proteins of this PHROG


2:DNA primase 1:protein of an unannotated phage

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K06919 K06919 : putative DNA primase/helicase no pathways 183 3

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003723 RNA binding
GO:0006355 regulation of transcription, DNA-templated
GO:0006281 DNA repair
GO:0016740 transferase activity
GO:0004003 ATP-dependent DNA helicase activity
GO:0000166 nucleotide binding
GO:0016887 ATPase activity
GO:0006270 DNA replication initiation
GO:0000160 phosphorelay signal transduction system
GO:0008134 transcription factor binding
GO:0005524 ATP binding
GO:0009236 cobalamin biosynthetic process
GO:0016020 membrane
GO:0003724 RNA helicase activity
GO:0051188 cofactor biosynthetic process
GO:0006260 DNA replication
GO:0003678 DNA helicase activity
GO:0009378 four-way junction helicase activity
GO:0000155 phosphorelay sensor kinase activity
GO:0004673 protein histidine kinase activity
GO:0019079 viral genome replication
GO:0003896 DNA primase activity
GO:0008270 zinc ion binding
GO:0043752 adenosylcobinamide kinase activity
GO:0003677 DNA binding
GO:0006310 DNA recombination

Loading in process