phrog_2597 is made of 56 protein sequences and is annotated as "DNA primase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
742.14 858 752


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p160743 no NCBI prot ID no annotation VI_04926 Bacilli_gi_452726042_108192_148054 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p164456 no NCBI prot ID no annotation VI_04844 Bacilli_gi_419800480_51741_91277 Viruses.
p170754 no NCBI prot ID no annotation VI_00870 Bacilli_gi_15674250_529606_568538 Viruses.
NC_028767_p72 YP_009196171.1 DNA primase NC_028767 Paenibacillus phage Vegas Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vegasvirus.
p175766 no NCBI prot ID no annotation VI_04976 Bacilli_gi_452729336_26767_65244 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p133021 no NCBI prot ID no annotation VI_01222 Clostridia_gi_547024125 Viruses.
p203882 no NCBI prot ID no annotation VI_06324 Erysipelotrichia_gi_218292494_3544_39853 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p123355 no NCBI prot ID no annotation VI_00604 Bacilli_gi_502362932_34964_77961 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p58466 no NCBI prot ID no annotation VI_01170 Clostridia_gi_223667572_323765_376572 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p206602 no NCBI prot ID no annotation VI_04994 Bacilli_gi_452729957_21553_57662 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p74776 no NCBI prot ID no annotation VI_12299 Negativicutes_gi_313892420 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p147231 no NCBI prot ID no annotation VI_00546 Bacilli_gi_501075363_2048191_2089324 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p123667 no NCBI prot ID no annotation VI_00487 Bacilli_gi_500897546_1522846_1565824 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p189476 no NCBI prot ID no annotation VI_05124 Bacilli_gi_481027788 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p206641 no NCBI prot ID no annotation VI_05101 Bacilli_gi_481026629_68607_104716 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p165036 no NCBI prot ID no annotation VI_05134 Bacilli_gi_481028301_48_39547 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p99742 no NCBI prot ID no annotation VI_00805 Bacilli_gi_288904223_449737_494815 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p183859 no NCBI prot ID no annotation VI_05441 Bacilli_gi_365822846 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p380539 no NCBI prot ID no annotation VI_00929 Bacilli_gi_522836001 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p206543 no NCBI prot ID no annotation VI_04883 Bacilli_gi_421147537_68568_104677 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p90006 no NCBI prot ID no annotation VI_12297 Negativicutes_gi_282848843_4123_50458 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
MG711464_p15 AUV56592.1 primase/helicase MG711464 Faecalibacterium phage FP_Lugh Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lughvirus; Faecalibacterium virus Lugh.
p176170 no NCBI prot ID no annotation VI_01163 Clostridia_gi_375092752_1310461_1348892 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p167154 no NCBI prot ID no annotation VI_00989 Bacilli_gi_94991497_531482_570812 Viruses.
p145131 no NCBI prot ID no annotation VI_00601 Bacilli_gi_502327608_33351_74643 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p206493 no NCBI prot ID no annotation VI_04986 Bacilli_gi_452729703_69077_105187 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_006557_p21 YP_164400.1 hypothetical protein NC_006557 Bacillus phage BCJA1c Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p351564 no NCBI prot ID no annotation VI_04021 Negativicutes_gi_548307056_100_19670 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p12216 no NCBI prot ID no annotation VI_01198 Clostridia_gi_331640230_194003_280818 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p62005 no NCBI prot ID no annotation VI_01275 Clostridia_gi_548208793 Viruses.
p190416 no NCBI prot ID no annotation VI_01345 Erysipelotrichia_gi_365833705_246515_283731 Viruses.
p373002 no NCBI prot ID no annotation VI_04505 Bacilli_gi_301299418 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p207764 no NCBI prot ID no annotation VI_04062 unknown_gi_547858986 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p162271 no NCBI prot ID no annotation VI_04738 Bacilli_gi_450065761_18938_58696 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p319399 no NCBI prot ID no annotation VI_04518 Bacilli_gi_312868614 Viruses.
p261904 no NCBI prot ID no annotation VI_04377 Bacilli_gi_77405268_13648_44448 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p198533 no NCBI prot ID no annotation VI_04974 Bacilli_gi_452729151_20879_57652 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p206739 no NCBI prot ID no annotation VI_05112 Bacilli_gi_481027343_68798_104907 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_025453_p25 YP_009103061.1 primase2 NC_025453 Enterococcus phage EFC-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p97511 no NCBI prot ID no annotation VI_04032 Negativicutes_gi_485071342 Viruses.
p95777 no NCBI prot ID no annotation VI_01242 Clostridia_gi_547805222 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p56031 no NCBI prot ID no annotation VI_01127 Clostridia_gi_545401873 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p123732 no NCBI prot ID no annotation VI_00553 Bacilli_gi_501481354_33522_76500 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p206690 no NCBI prot ID no annotation VI_05228 Bacilli_gi_481031398_68858_104967 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MG727697_p57 AUS03457.1 DNA primase MG727697 Paenibacillus phage Dragolir Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vegasvirus; unclassified Vegasvirus.
p189068 no NCBI prot ID no annotation VI_05073 Bacilli_gi_429204493 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p167835 no NCBI prot ID no annotation VI_01231 Clostridia_gi_547728748 Viruses.
p280640 no NCBI prot ID no annotation VI_01225 Clostridia_gi_547209477_0_28549 Viruses.
p254984 no NCBI prot ID no annotation VI_04583 Bacilli_gi_417973945_7683_39121 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p163274 no NCBI prot ID no annotation VI_05412 Bacilli_gi_545669026_54257_93947 Viruses.
p157010 no NCBI prot ID no annotation VI_00815 Bacilli_gi_242362035_373302_413505 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p205905 no NCBI prot ID no annotation VI_00452 Bacilli_gi_323649861_519095_555231 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p137486 no NCBI prot ID no annotation VI_05411 Bacilli_gi_560295271_60173_102174 Viruses; unclassified bacterial viruses.
p123608 no NCBI prot ID no annotation VI_00485 Bacilli_gi_500754380_342141_385119 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p229265 no NCBI prot ID no annotation VI_04175 Actinobacteria_gi_484063094_9427_43290 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p229226 no NCBI prot ID no annotation VI_04176 Actinobacteria_gi_484064923_31_33894 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_16 2054 DNA helicase DNA, RNA and nucleotide metabolism 21 3.31E-37 27.6
phrog_140 680 RusA-like Holliday junction resolvase DNA, RNA and nucleotide metabolism 20 3.11E-45 35.63
phrog_774 185 no annotation unknown function 16 5.32E-45 35.4
phrog_1335 111 no annotation unknown function 5 3.41E-15 5.59
phrog_16687 5 no annotation unknown function 3 6.88E-16 6.28
phrog_36956 2 no annotation unknown function 2 0 1000
phrog_33704 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1156 DNA primase DNA, RNA and nucleotide metabolism 92.2 0.022 14-67 / 218-273
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 94.4 0.0034 368-416 / 13-45
phrog_1284 no annotation unknown function 97.9 1.7E-08 361-529 / 27-205
phrog_13004 no annotation unknown function 95.8 0.00026 336-520 / 62-241
phrog_1366 no annotation unknown function 96.5 3.5E-05 369-486 / 14-106
phrog_15962 DNA primase DNA, RNA and nucleotide metabolism 96.3 6.7E-05 12-90 / 210-286
phrog_19 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 98.7 7.3E-12 356-550 / 184-382
phrog_239 DNA primase/helicase DNA, RNA and nucleotide metabolism 98.6 2.5E-11 361-547 / 301-506
phrog_243 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 95.7 0.00041 364-547 / 30-221
phrog_25693 no annotation unknown function 96.7 1.4E-05 359-521 / 40-214
phrog_2850 no annotation unknown function 98.6 2.9E-11 326-541 / 110-330
phrog_29234 no annotation unknown function 97.2 1.2E-06 9-105 / 125-227
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 94.5 0.0031 340-517 / 9-181
phrog_296 DNA transposition protein integration and excision 90.9 0.045 281-521 / 6-204
phrog_3123 no annotation unknown function 99.2 4.4E-15 338-536 / 282-504
phrog_3228 replicative helicase-primase DNA, RNA and nucleotide metabolism 96.6 2.4E-05 355-544 / 341-526
phrog_6012 DNA helicase DNA, RNA and nucleotide metabolism 98.3 9.2E-10 340-544 / 108-314
phrog_6357 no annotation unknown function 92.7 0.017 361-550 / 23-191
phrog_6891 ATPase other 96.4 4.3E-05 364-521 / 29-155
phrog_906 DNA polymerase/primase DNA, RNA and nucleotide metabolism 99.3 1.7E-15 350-520 / 552-719
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 92.6 0.018 710-734 / 19-43

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF16793.4 RepB DNA-primase from phage plasmid 1.8E-12 215-350 / 47-170
PF03796.14 DnaB-like helicase C terminal domain 2.7E-10 366-565 / 2-215
PF00154.20 recA bacterial DNA recombination protein 1.2E-09 365-566 / 32-222
PF06745.12 KaiC 1.4E-09 367-534 / 2-166
PF08423.10 Rad51 2.3E-09 364-534 / 17-188
PF09807.8 Elongation complex protein 6 1.9E-08 370-567 / 1-224
PF05621.10 Bacterial TniB protein 2.7E-08 386-636 / 39-252
PF05625.10 PAXNEB protein 2.1E-07 365-431 / 18-77
PF07088.10 GvpD gas vesicle protein 3.6E-05 365-430 / 239-297
PF13481.5 AAA domain 7.2E-07 366-534 / 11-184
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 2.3E-06 369-410 / 1-39
PF08800.9 VirE N-terminal domain 3.8E-06 224-322 / 13-114
PF08707.10 Primase C terminal 2 (PriCT-2) 9.8E-06 29-99 / 5-74
PF07693.13 KAP family P-loop domain 1.9E-05 383-410 / 29-56
PF00308.17 Bacterial dnaA protein 5.4E-05 385-410 / 33-58
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 6E-05 388-407 / 1-20
PF09820.8 Predicted AAA-ATPase 6.8E-05 385-410 / 31-56
PF10443.8 RNA12 protein 7.8E-05 384-408 / 16-41
PF03846.13 Cell division inhibitor SulA 8.5E-05 371-432 / 10-63
PF13173.5 AAA domain 9E-05 385-408 / 2-25
PF10923.7 P-loop Domain of unknown function (DUF2791) 9.6E-05 384-410 / 48-74
PF05673.12 Protein of unknown function (DUF815) 9.8E-05 384-410 / 53-79
PF05707.11 Zonular occludens toxin (Zot) 0.0001 387-409 / 2-25
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.00011 387-431 / 2-37
PF04665.11 Poxvirus A32 protein 0.00027 382-410 / 10-38
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 0.00033 384-409 / 44-69
PF00265.17 Thymidine kinase 0.00036 385-410 / 1-26
PF01637.17 ATPase domain predominantly from Archaea 0.0004 384-410 / 19-45
PF14516.5 AAA-like domain 0.00046 384-410 / 29-55
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.00047 385-410 / 4-29
PF13479.5 AAA domain 0.00068 385-406 / 2-23
PF01896.18 DNA primase small subunit 0.001 263-330 / 26-107
PF13177.5 DNA polymerase III, delta subunit 0.0011 385-409 / 19-43
PF13401.5 AAA domain 0.0011 384-410 / 4-30
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.0012 388-409 / 1-22
PF12775.6 P-loop containing dynein motor region D3 0.0012 383-410 / 31-58
PF07652.13 Flavivirus DEAD domain 0.0012 384-408 / 3-28
PF01078.20 Magnesium chelatase, subunit ChlI 0.0014 384-410 / 21-47
PF04851.14 Type III restriction enzyme, res subunit 0.0025 384-410 / 22-48
PF03215.14 Rad17 cell cycle checkpoint protein 0.0028 383-409 / 43-69
PF05729.11 NACHT domain 0.0034 387-410 / 2-25
PF00488.20 MutS domain V 0.0036 388-409 / 1-22
PF05970.13 PIF1-like helicase 0.0053 384-410 / 21-47
PF09818.8 Predicted ATPase of the ABC class 0.0055 381-406 / 244-268
PF09848.8 Uncharacterized conserved protein (DUF2075) 0.006 386-409 / 2-25
PF02456.14 Adenovirus IVa2 protein 0.0074 384-405 / 80-100
PF00625.20 Guanylate kinase 0.0078 385-409 / 2-26

Annotations of the NCBI proteins of this PHROG


2:DNA primase 1:primase2 1:primase/helicase 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K07505 repA : regulatory protein RepA no pathways 1562 52

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0000160 phosphorelay signal transduction system
GO:0005524 ATP binding
GO:0009236 cobalamin biosynthetic process
GO:0051782 negative regulation of cell division
GO:0033588 Elongator holoenzyme complex
GO:0030983 mismatched DNA binding
GO:0051188 cofactor biosynthetic process
GO:0016020 membrane
GO:0002098 tRNA wobble uridine modification
GO:0006269 DNA replication, synthesis of RNA primer
GO:0006298 mismatch repair
GO:0003697 single-stranded DNA binding
GO:0000166 nucleotide binding
GO:0006281 DNA repair
GO:0004673 protein histidine kinase activity
GO:0000723 telomere maintenance
GO:0016817 hydrolase activity, acting on acid anhydrides
GO:0019073 viral DNA genome packaging
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0008026 ATP-dependent helicase activity
GO:0003896 DNA primase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0009432 SOS response
GO:0004797 thymidine kinase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0003678 DNA helicase activity
GO:0006260 DNA replication
GO:0000155 phosphorelay sensor kinase activity

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