phrog_25983 is made of 3 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
174.33 194 171


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KU574722_p528 AMM44091.1 HNH endonuclease KU574722 Pectobacterium phage CBB Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Mimasvirus; Pectinobacterium virus CBB.
KY630187_p523 AQW89048.1 HNH endonuclease KY630187 Serratia phage BF Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Eneladusvirus; Serratia virus BF.
NC_019401_p521 YP_006987623.1 HNH endonuclease NC_019401 Cronobacter phage vB_CsaM_GAP32 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Mimasvirus; Cronobacter virus GAP32.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_27418 3 no annotation unknown function 3 0 1000
phrog_27425 3 membrane protein moron, auxiliary metabolic gene and host takeover 2 1.65E-16 6.91

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 96.4 4.8E-05 9-72 / 100-156
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 95.3 0.00089 10-69 / 146-200
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.2E-05 10-64 / 16-59
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 90.7 0.049 9-69 / 61-113
phrog_15463 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00039 35-71 / 151-184
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 96.8 1E-05 10-71 / 80-132
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.00022 13-69 / 19-74
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 98.0 9.4E-09 33-80 / 44-86
phrog_22514 HNH endonuclease DNA, RNA and nucleotide metabolism 91.0 0.042 10-84 / 66-134
phrog_23285 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.7E-06 8-80 / 46-135
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 7.8E-06 33-84 / 124-169
phrog_25420 HNH endonuclease DNA, RNA and nucleotide metabolism 99.3 3.3E-16 33-134 / 71-167
phrog_32453 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0019 5-97 / 60-136
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 96.3 7.5E-05 6-69 / 24-83
phrog_35175 HNH endonuclease DNA, RNA and nucleotide metabolism 98.0 7.2E-09 29-95 / 76-143
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 5.8E-06 12-70 / 25-72
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 92.8 0.016 8-65 / 48-95
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.8E-06 13-68 / 8-53
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 92.2 0.023 39-65 / 56-82
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.4E-05 10-69 / 68-112
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 7E-06 33-68 / 119-154
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00034 11-68 / 112-166
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 90.2 0.06 25-69 / 35-75

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13395.5 HNH endonuclease 3.9E-07 42-75 / 18-51
PF01844.22 HNH endonuclease 1.1E-06 19-74 / 1-47
PF05315.10 ICEA Protein 1.9E-06 8-75 / 85-150
PF14279.5 HNH endonuclease 4.5E-06 19-76 / 1-46
PF05766.11 Bacteriophage Lambda NinG protein 5.8E-06 7-75 / 77-136
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 9.3E-06 42-77 / 264-298
PF13391.5 HNH endonuclease 2E-05 42-75 / 12-45
PF06147.10 Protein of unknown function (DUF968) 6.3E-05 14-75 / 125-174

Annotations of the NCBI proteins of this PHROG


3:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity

Loading in process