phrog_2633 is made of 55 protein sequences and is annotated as "endonuclease VII"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
145.4 277 135


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
JF704113_p96 AEK07661.1 endonuclease VII JF704113 Mycobacterium phage UPIE Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bronvirus; unclassified Bronvirus.
NC_014461_p96 YP_003857227.1 gp96 NC_014461 Mycobacterium virus Bron Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bronvirus.
JN600672_p99 AEZ50774.1 hypothetical protein JN600672 Mycobacterium phage Fezzik Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bronvirus; unclassified Bronvirus.
NC_031074_p22 YP_009287492.1 endonuclease VII NC_031074 Gordonia phage Bantam Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bantamvirus; Gordonia virus Bantam.
NC_016766_p3 YP_005098302.1 endonuclease NC_016766 Synechococcus phage S-CBS4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MF285620_p43 ASZ79022.1 hypothetical protein MF285620 Serratia phage 2050H2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teetrevirus; Serratia virus 2050H2.
MF919520_p34 ATN90667.1 endonuclease VII MF919520 Gordonia phage Lozinak Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Smoothievirus; unclassified Smoothievirus.
NC_031230_p33 YP_009301092.1 endonuclease VII NC_031230 Gordonia phage Yvonnetastic Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yvonnevirus; Gordonia virus Yvonnetastic.
NC_015938_p83 YP_004782458.1 putative endonuclease NC_015938 Salmonella phage 7-11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
KJ936628_p1 AII27481.1 endonuclease VII KJ936628 Vibrio phage VPp1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
NC_031029_p35 YP_009281197.1 endonuclease VII NC_031029 Gordonia phage Cucurbita Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Smoothievirus; unclassified Smoothievirus.
NC_030696_p34 YP_009269155.1 endonuclease VII NC_030696 Gordonia phage Smoothie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Smoothievirus.
NC_030901_p33 YP_009273076.1 EndoVII NC_030901 Gordonia phage ClubL Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Smoothievirus.
KY652724_p42 AUF73719.1 hypothetical protein KY652724 Klebsiella phage vB_KpnP_IL33 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Przondovirus; Klebsiella virus IL33.
MF919537_p34 AUE23678.1 endonuclease VII MF919537 Gordonia phage Toniann Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Smoothievirus; unclassified Smoothievirus.
NC_030936_p35 YP_009276154.1 EndoVII NC_030936 Gordonia phage Bachita Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Smoothievirus.
MG770214_p16 AUV60620.1 HNH endonuclease MG770214 Gordonia phage SteveFrench Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Montyvirus; Gordonia virus Stevefrench.
NC_009551_p35 YP_001285800.1 PfWMP3_35 NC_009551 Phormidium phage Pf-WMP3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
KX130726_p12 ANN86236.1 endonuclease VII KX130726 Escherichia phage ECA2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teetrevirus; Escherichia virus ECA2.
MF668280_p53 ASZ74628.1 HNH endonuclease MF668280 Mycobacterium phage Phabba Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
NC_006820_p182 YP_195212.1 homing endonuclease NC_006820 Synechococcus phage S-PM2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
MF979559_p26 ATS93387.1 recombination endonuclease VII MF979559 Ralstonia phage DU_RP_I Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Gyeongsanvirus; Ralstonia virus DURPI.
NC_020851_p28 YP_007674393.1 hypothetical protein NC_020851 Synechococcus phage S-SKS1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Llyrvirus; Synechococcus virus SSKS1.
NC_015463_p63 YP_004421517.1 endonuclease NC_015463 Synechococcus phage S-CBS2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MG018930_p130 ATW58350.1 recombination endonuclease VII MG018930 Pseudomonas phage ventosus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
NC_022744_p40 YP_008766754.1 endonuclease VII NC_022744 Erwinia phage FE44 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Berlinvirus; Erwinia virus FE44.
NC_011042_p42 YP_002003777.1 gp13.5 NC_011042 Enterobacteria phage EcoDS1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Kayfunavirus; Escherichia virus EcoDS1.
KY652725_p29 AUF73727.1 endonuclease VII KY652725 Klebsiella phage vB_KpnP_BIS33 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Przondovirus; Klebsiella virus BIS33.
NC_025451_p36 YP_009102831.1 hypothetical protein NC_025451 Yersinia phage vB_YenP_AP5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teetrevirus; Yersinia virus AP5.
KY652724_p25 ARB12431.1 endonuclease VII KY652724 Klebsiella phage vB_KpnP_IL33 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Przondovirus; Klebsiella virus IL33.
NC_001271_p47 NP_072072.1 putative 13.5 protein NC_001271 Yersinia phage phiYeO3-12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Teetrevirus; Yersinia virus YeO3-12.
NC_018280_p35 YP_006560920.1 putative endonuclease NC_018280 Celeribacter phage P12053L Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
MG711516_p42 AUO78200.1 hypothetical protein MG711516 Ralstonia phage RsoP1EGY Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Gyeongsanvirus; Ralstonia virus RsoP1EGY.
NC_030906_p50 YP_009273532.1 hypothetical protein NC_030906 Gordonia phage GMA6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bendigovirus; Gordonia virus GMA6.
MG711516_p24 AUO78184.1 hypothetical protein MG711516 Ralstonia phage RsoP1EGY Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Gyeongsanvirus; Ralstonia virus RsoP1EGY.
NC_028800_p34 YP_009198662.1 endonuclease VII NC_028800 Klebsiella phage K5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Przondovirus.
MG518519_p3 ATW69321.1 endonuclease VII MG518519 Streptomyces phage Manuel Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
KU197013_p37 AMW36098.1 endonuclease VII KU197013 Xanthomonas phage XAJ24 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Pradovirus; Xanthomonas virus XAJ24.
MG099945_p61 ATW60354.1 endonuclease VII MG099945 Mycobacterium phage Koko Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus; unclassified Fromanvirus.
MG018930_p116 ATW58336.1 recombination endonuclease VII MG018930 Pseudomonas phage ventosus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
NC_020872_p47 YP_007676893.1 endonuclease VII NC_020872 Cyanophage SS120-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Banchanvirus; Prochlorococcus virus SS120-1.
KU130129_p131 AMR57864.1 hypothetical protein KU130129 Pseudomonas phage vB_PsyM_KIL4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Flaumdravirus; Pseudomonas virus KIL2.
NC_022965_p60 YP_008856833.1 EndoVII NC_022965 Mycobacterium phage CloudWang3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus; unclassified Fromanvirus.
p437390 no NCBI prot ID no annotation VI_00013 SAR406_cluster_bacterium_SCGC_AAA160_I06 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_026590_p18 YP_009124761.1 homoendonuclease NC_026590 Mycobacterium phage Gaia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gaiavirus.
MF185728_p71 ATG86482.1 endonuclease VII MF185728 Mycobacterium phage Finemlucis Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bronvirus; unclassified Bronvirus.
NC_008206_p93 YP_655958.1 gp93 NC_008206 Mycobacterium phage Wildcat Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wildcatvirus.
NC_031124_p100 YP_009292614.1 hypothetical protein NC_031124 Mycobacterium phage Gardann Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bronvirus; unclassified Bronvirus.
NC_023732_p98 YP_009017323.1 gp98 NC_023732 Mycobacterium virus Rumpelstiltskin Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bronvirus.
NC_008694_p20 YP_919002.1 hypothetical protein NC_008694 Yersinia phage Berlin Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Berlinvirus; Yersinia virus Berlin.
LN610572_p103 CEF89033.1 putative endonuclease VII LN610572 Pseudomonas phage vB_PaeM_C2-10_Ab02 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Pakpunavirus; Pseudomonas virus CAb02.
MF974178_p70 ATI16043.1 endonuclease VII MF974178 Pseudomonas phage YS35 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Pakpunavirus; unclassified Pakpunavirus.
NC_006883_p287 YP_214518.1 T4-like hypothetical protein NC_006883 Prochlorococcus phage P-SSM2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Salacisavirus; Prochlorococcus virus PSSM2.
MG593803_p60 AUG87324.1 HNH endonuclease MG593803 Streptomyces phage Rowa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rowavirus; Streptomyces virus Rowa.
NC_031230_p157 YP_009301216.1 endonuclease VII NC_031230 Gordonia phage Yvonnetastic Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Yvonnevirus; Gordonia virus Yvonnetastic.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_123 746 tail terminator connector 8 5.38E-16 6.39
phrog_476 283 major tail protein tail 8 8.45E-20 10.19
phrog_338 362 HNH endonuclease DNA, RNA and nucleotide metabolism 5 6.70E-12 2.3
phrog_805 179 internal virion protein head and packaging 4 2.93E-11 1.65
phrog_16667 5 DNA polymerase I DNA, RNA and nucleotide metabolism 2 1.59E-11 1.92
phrog_27239 3 major head protein head and packaging 2 1.59E-12 2.92

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 99.6 2E-19 3-132 / 3-168
phrog_11865 endonuclease VII DNA, RNA and nucleotide metabolism 98.3 5.9E-10 92-132 / 1-55
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 93.4 0.0099 61-119 / 130-202
phrog_12813 no annotation unknown function 96.2 9.5E-05 6-49 / 150-193
phrog_17507 endonuclease VII DNA, RNA and nucleotide metabolism 98.7 1.1E-11 93-133 / 1-42
phrog_18715 no annotation unknown function 94.8 0.0019 8-44 / 78-114
phrog_1985 HNH endonuclease DNA, RNA and nucleotide metabolism 91.7 0.03 17-132 / 4-149
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 93.9 0.0063 64-116 / 3-73
phrog_2255 HNH endonuclease DNA, RNA and nucleotide metabolism 98.8 1.7E-12 8-100 / 1-87
phrog_2340 endonuclease DNA, RNA and nucleotide metabolism 97.6 1.2E-07 6-50 / 2-47
phrog_24058 no annotation unknown function 90.7 0.049 8-47 / 4-43
phrog_2539 no annotation unknown function 95.1 0.0012 8-50 / 100-142
phrog_2914 endonuclease VII DNA, RNA and nucleotide metabolism 100.0 8.4E-37 53-134 / 14-98
phrog_307 endonuclease VII DNA, RNA and nucleotide metabolism 100.0 2.9E-36 4-133 / 7-134
phrog_30859 no annotation unknown function 97.2 1.3E-06 8-52 / 1-45
phrog_3273 no annotation unknown function 92.4 0.02 7-51 / 20-67
phrog_3314 no annotation unknown function 91.4 0.035 8-48 / 4-48
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 90.2 0.059 73-116 / 24-82
phrog_36860 HNH endonuclease DNA, RNA and nucleotide metabolism 97.8 3.9E-08 70-133 / 30-110
phrog_423 endonuclease VII DNA, RNA and nucleotide metabolism 99.6 3.8E-20 71-134 / 15-95
phrog_4283 no annotation unknown function 91.3 0.037 59-78 / 30-49
phrog_4723 endonuclease VII DNA, RNA and nucleotide metabolism 95.6 0.00045 7-50 / 14-62
phrog_5558 Lar-like restriction alleviation protein moron, auxiliary metabolic gene and host takeover 97.8 3.4E-08 7-50 / 2-49
phrog_6611 no annotation unknown function 96.6 1.9E-05 7-46 / 139-178
phrog_6762 no annotation unknown function 94.0 0.0058 4-50 / 155-201
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 90.3 0.057 36-115 / 69-153

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 4.9E-07 125-167 / 253-298
PF02945.14 Recombination endonuclease VII 5.2E-07 113-180 / 14-88
PF05315.10 ICEA Protein 4.4E-06 112-164 / 80-149
PF13395.5 HNH endonuclease 1E-05 128-165 / 1-51
PF14279.5 HNH endonuclease 2.5E-05 128-167 / 1-47
PF05766.11 Bacteriophage Lambda NinG protein 5.6E-05 121-165 / 82-136
PF01844.22 HNH endonuclease 6.8E-05 128-164 / 1-47
PF13391.5 HNH endonuclease 0.00073 128-165 / 1-45
PF06147.10 Protein of unknown function (DUF968) 0.0032 124-164 / 126-173

Annotations of the NCBI proteins of this PHROG


21:endonuclease VII 11:hypothetical protein 4:endonuclease 3:HNH endonuclease 3:EndoVII 3:recombination endonuclease VII 1:protein of an unannotated phage 1:T4-like hypothetical protein 1:endo VII 1:homing endonuclease 1:gp13.5 1:Endo VII 1:homoendonuclease 1:PfWMP3_35 1:13.5 protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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