phrog_2649 is made of 54 protein sequences and is annotated as "endolysin"
Functional category: lysis


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
279.56 529 256


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_028782_p24 YP_009197493.1 endolysin NC_028782 Bacillus phage Pavlov Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus; unclassified Pagevirus.
NC_028926_p25 YP_009210060.1 peptidase NC_028926 Bacillus phage Palmer Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_027394_p24 YP_009152823.1 peptidase NC_027394 Bacillus phage Pookie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_022764_p24 YP_008770531.1 endolysin NC_022764 Bacillus phage Page Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_027372_p22 YP_009151490.1 peptidase NC_027372 Bacillus phage Pascal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_029069_p25 YP_009223175.1 spore cortex-lytic enzyme NC_029069 Bacillus phage BM5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_022770_p24 YP_008771342.1 L-alanyl-D-glutamate peptidase NC_022770 Bacillus phage Pony Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Pagevirus.
NC_023612_p22 YP_009010493.1 lysin NC_023612 Geobacillus phage GBK2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p52397 no NCBI prot ID no annotation VI_01311 Clostridia_gi_514231917 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
MG711467_p75 AUV56877.1 endolysin MG711467 Faecalibacterium phage FP_Taranis Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Taranisvirus; Faecalibacterium virus Taranis.
MG711465_p65 AUV56684.1 endolysin, peptidase M15 family MG711465 Faecalibacterium phage FP_Brigit Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Brigitvirus; Faecalibacterium virus Brigit.
MG962367_p24 AVO25202.1 lysin A MG962367 Microbacterium phage Gelo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839020_p24 AUX82923.1 lysin A MG839020 Microbacterium phage Kale Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045560_p24 AVR56353.1 lysin A MH045560 Microbacterium phage Nagem Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045558_p24 AVR56226.1 lysin A MH045558 Microbacterium phage Dave Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839029_p24 AUX83488.1 lysin A MG839029 Microbacterium phage Ilzat Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; Microbacterium virus Ilzat.
MG839015_p24 AUX82611.1 lysin A MG839015 Microbacterium phage Aubergine Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839016_p24 AUX82673.1 lysin A MG839016 Microbacterium phage AxiPup Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839018_p24 AUX82798.1 lysin A MG839018 Microbacterium phage Espinosa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045563_p24 AVR56504.1 lysin A MH045563 Microbacterium phage Robinson Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839022_p24 AUX83048.1 lysin A MG839022 Microbacterium phage Ludgate Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839025_p24 AUX83237.1 lysin A MG839025 Microbacterium phage Raccoon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839027_p23 AUX83361.1 lysin A MG839027 Microbacterium phage Eleri Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Elerivirus; Microbacterium virus Eleri.
MG839021_p24 AUX82985.1 lysin A MG839021 Microbacterium phage Knox Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839026_p24 AUX83300.1 lysin A MG839026 Microbacterium phage Superfresh Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG944222_p24 AVJ51469.1 lysin A MG944222 Microbacterium phage StingRay Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839023_p24 AUX83110.1 lysin A MG839023 Microbacterium phage Peep Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH047631_p27 AVR56900.1 lysin A MH047631 Microbacterium phage Triscuit Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MH045565_p24 AVR56629.1 lysin A MH045565 Microbacterium phage Antoinette Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045559_p24 AVR56289.1 lysin A MH045559 Microbacterium phage Etna Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG962360_p24 AVO24415.1 lysin A MG962360 Microbacterium phage AlexAdler Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839019_p24 AUX82860.1 lysin A MG839019 Microbacterium phage Hamlet Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; Microbacterium virus Hamlet.
MH045562_p24 AVR56441.1 lysin A MH045562 Microbacterium phage Raptor Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839017_p24 AUX82736.1 lysin A MG839017 Microbacterium phage Baines Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839030_p24 AUX83550.1 lysin A MG839030 Microbacterium phage Balsa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839024_p24 AUX83174.1 lysin A MG839024 Microbacterium phage Peppino Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG944219_p24 AVJ51221.1 lysin A MG944219 Microbacterium phage PuppyEggo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045564_p24 AVR56567.1 lysin A MH045564 Microbacterium phage TeddyBear Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045555_p25 AVR56110.1 lysin A MH045555 Microbacterium phage BeeBee8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045554_p24 AVR56046.1 lysin A MH045554 Microbacterium phage Bandik Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG925352_p24 AVJ50497.1 lysin A MG925352 Microbacterium phage Nattles Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG920061_p24 AVJ49226.1 lysin A MG920061 Microbacterium phage Bonino Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
NC_019487_p131 YP_007003388.1 L-alanoyl-D-glutamate peptidase NC_019487 Bacillus phage SP-10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; unclassified Spounavirinae.
NC_031245_p69 YP_009302456.1 L-alanoyl-D-glutamate peptidase NC_031245 Bacillus phage SP-15 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Thornevirus; Bacillus virus SP15.
NC_022761_p104 YP_008770038.1 endolysin NC_022761 Bacillus phage CampHawk Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Okubovirus.
NC_011421_p103 YP_002300379.1 gp19.3 NC_011421 Bacillus virus SPO1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Okubovirus.
KY368639_p101 APZ82341.1 endolysin KY368639 Bacillus phage vB_BsuM-Goe2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Spounavirinae; Okubovirus; unclassified Okubovirus; Bacillus virus vB_BsuM-Goe2.
NC_027374_p30 YP_009151593.1 peptidase NC_027374 Bacillus phage Moonbeam Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; Bacillus virus Moonbeam.
NC_022774_p58 YP_008771960.1 L-alanyl-D-glutamate peptidase NC_022774 Bacillus phage Slash Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Slashvirus.
NC_030920_p33 YP_009274740.1 autolysin NC_030920 Bacillus phage Eldridge Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Herelleviridae; Bastillevirinae; unclassified Bastillevirinae.
NC_022767_p60 YP_008770774.1 endolysin NC_022767 Bacillus phage Staley Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Slashvirus.
NC_028777_p56 YP_009196941.1 L-alanyl-D-glutamate peptidase NC_028777 Bacillus phage Stills Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Slashvirus.
NC_028856_p58 YP_009203662.1 peptidase NC_028856 Bacillus phage Stahl Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Slashvirus.
NC_029073_p53 YP_009223760.1 endolysin-like protein NC_029073 Geobacillus virus E3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3432 42 minor tail protein tail 30 3.67E-115 105.56
phrog_4153 34 membrane protein moron, auxiliary metabolic gene and host takeover 30 5.13E-121 111.41
phrog_263 455 holin lysis 7 1.07E-15 6.09
phrog_11899 8 no annotation unknown function 5 6.10E-23 13.34
phrog_1625 92 involved in bacteriocin production or immunity moron, auxiliary metabolic gene and host takeover 5 1.54E-15 5.93
phrog_1048 142 no annotation unknown function 4 8.68E-12 2.18

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_102 endolysin lysis 91.6 0.031 201-254 / 12-67
phrog_1224 endolysin head and packaging 92.9 0.015 131-216 / 13-89
phrog_12853 no annotation unknown function 95.5 0.00063 204-232 / 96-124
phrog_13118 endolysin lysis 95.0 0.0015 29-84 / 482-527
phrog_14712 chitinase moron, auxiliary metabolic gene and host takeover 90.0 0.064 231-255 / 195-219
phrog_1493 endolysin lysis 92.9 0.014 131-187 / 247-305
phrog_14988 peptidase other 96.9 5.7E-06 201-255 / 176-229
phrog_1512 endolysin lysis 94.9 0.0018 149-241 / 208-284
phrog_15213 no annotation unknown function 94.6 0.0028 148-255 / 176-283
phrog_15351 endolysin lysis 99.7 4.9E-21 14-119 / 27-144
phrog_16428 endolysin lysis 97.8 2.8E-08 202-255 / 462-519
phrog_16823 tail length tape measure protein tail 96.5 3.7E-05 11-116 / 36-165
phrog_17001 endolysin lysis 94.5 0.0029 201-236 / 54-90
phrog_17214 endolysin lysis 92.6 0.018 126-186 / 247-312
phrog_17373 peptidase other 92.4 0.02 13-126 / 38-137
phrog_1768 endolysin lysis 98.3 8.9E-10 15-113 / 13-109
phrog_18032 endolysin lysis 96.9 6.1E-06 161-255 / 183-270
phrog_21825 endolysin lysis 91.0 0.043 170-255 / 174-248
phrog_23178 peptidase other 97.9 1.5E-08 29-113 / 430-510
phrog_23452 no annotation unknown function 97.5 1.9E-07 192-255 / 54-122
phrog_23582 no annotation unknown function 96.5 3.6E-05 141-255 / 205-325
phrog_315 endolysin lysis 90.1 0.062 220-255 / 84-130
phrog_465 endolysin lysis 99.0 2.2E-13 4-112 / 12-124
phrog_5115 ferredoxin moron, auxiliary metabolic gene and host takeover 99.7 3.5E-21 4-125 / 10-135
phrog_6219 endolysin lysis 96.6 2.1E-05 195-255 / 254-326
phrog_6523 endolysin lysis 99.7 1.1E-22 11-117 / 24-141
phrog_6707 endolysin lysis 97.9 1.4E-08 193-255 / 179-243
phrog_880 endolysin lysis 97.3 8E-07 201-255 / 373-431
phrog_894 endolysin lysis 97.2 1.4E-06 12-114 / 27-122
phrog_9589 endolysin lysis 96.1 0.00012 192-255 / 206-275

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01427.16 D-ala-D-ala dipeptidase 6.8E-17 5-145 / 20-170
PF02557.16 D-alanyl-D-alanine carboxypeptidase 6.1E-16 24-143 / 2-129
PF08924.10 Domain of unknown function (DUF1906) 2.2E-10 343-396 / 2-64
PF05951.12 Bacterial protein of unknown function (DUF882) 8.1E-10 22-146 / 50-150
PF08291.10 Peptidase M15 2.3E-09 5-101 / 1-88
PF01085.17 Hedgehog amino-terminal signalling domain 1.7E-06 23-140 / 74-162
PF13539.5 D-alanyl-D-alanine carboxypeptidase 2.4E-05 85-141 / 6-86
PF01471.17 Putative peptidoglycan binding domain 0.0011 281-330 / 10-56
PF09374.9 Predicted Peptidoglycan domain 0.0017 291-335 / 17-57

Annotations of the NCBI proteins of this PHROG


31:lysin A 6:endolysin 5:peptidase 3:L-alanyl-D-glutamate peptidase 2:L-alanoyl-D-glutamate peptidase 1:endolysin (L-alanoyl-D-glutamate peptidase) 1:endolysin, peptidase M15 family 1:lysin 1:endolysin-like protein 1:autolysin 1:spore cortex-lytic enzyme

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K17733 cwlK : peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK [EC:3.4.-.-] no pathways 253 20

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0008233 peptidase activity
GO:0006508 proteolysis
GO:0008237 metallopeptidase activity
GO:0005618 cell wall
GO:0007267 cell-cell signaling
GO:0016805 dipeptidase activity

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