phrog_26674 is made of 3 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
205.33 219 217


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_019420_p18 YP_006990448.1 hypothetical protein NC_019420 Edwardsiella phage KF-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Kafunavirus.
AB757801_p19 BAM63115.1 hypothetical protein AB757801 Edwardsiella phage IW-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Kafunavirus; Edwardsiella virus KF1; Edwardsiella phage KF-1.
NC_021776_p46 YP_008239702.1 HTH_Hin protein NC_021776 Vibrio phage VPMS1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Kafunavirus; unclassified Kafunavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_10459 10 no annotation unknown function 3 1.15E-19 10.06

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1206 terminase small subunit head and packaging 91.7 0.031 127-160 / 3-36
phrog_1303 DNA binding protein DNA, RNA and nucleotide metabolism 93.7 0.0077 124-209 / 28-124
phrog_1373 transcriptional regulator transcription regulation 93.0 0.014 131-165 / 34-68
phrog_14131 DNA binding protein DNA, RNA and nucleotide metabolism 92.1 0.024 140-208 / 17-92
phrog_151 transposase integration and excision 92.0 0.025 171-212 / 4-47
phrog_1740 RNA polymerase sigma factor transcription regulation 91.7 0.03 173-213 / 126-167
phrog_22784 no annotation unknown function 93.6 0.0081 178-211 / 11-40
phrog_2538 terminase small subunit head and packaging 90.7 0.048 187-212 / 18-43
phrog_268 no annotation unknown function 90.4 0.055 190-211 / 18-39
phrog_3218 terminase small subunit head and packaging 93.4 0.0098 168-209 / 13-54
phrog_323 transcriptional regulator, D5-like transcription regulation 92.9 0.014 99-198 / 15-120
phrog_3282 sigma factor transcription regulation 90.1 0.063 170-211 / 14-55
phrog_351 RNA polymerase sigma factor transcription regulation 90.3 0.057 190-214 / 196-220
phrog_4494 no annotation unknown function 91.4 0.036 136-211 / 12-96
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.6 0.0027 167-209 / 57-100
phrog_5536 no annotation unknown function 93.3 0.01 130-162 / 10-42
phrog_6081 no annotation unknown function 90.3 0.058 134-210 / 12-97
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 95.1 0.0013 89-166 / 9-93
phrog_66 excisionase and transcriptional regulator integration and excision 95.2 0.001 189-211 / 10-32
phrog_6831 transcriptional regulator transcription regulation 91.5 0.033 132-178 / 6-48
phrog_7168 homing endonuclease DNA, RNA and nucleotide metabolism 91.9 0.026 98-207 / 134-258

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04936.11 Protein of unknown function (DUF658) 0.00062 189-213 / 14-38
PF01710.15 Transposase 0.00095 188-214 / 17-43
PF00292.17 'Paired box' domain 0.00092 188-214 / 32-58
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.00067 188-214 / 12-38
PF05344.10 Domain of Unknown Function (DUF746) 0.0098 97-125 / 9-37
PF07141.10 Putative bacteriophage terminase small subunit 0.0074 93-125 / 24-56
PF09607.9 Brinker DNA-binding domain 0.00052 190-214 / 26-50
PF07750.10 GcrA cell cycle regulator 0.0065 92-125 / 10-44
PF06322.10 Phage NinH protein 0.0013 188-214 / 15-41
PF12759.6 InsA C-terminal domain 0.00019 188-213 / 20-45
PF08822.10 Protein of unknown function (DUF1804) 0.0011 188-214 / 18-44
PF06627.10 Protein of unknown function (DUF1153) 0.0053 188-215 / 45-72
PF10654.8 Protein of unknown function (DUF2481) 0.00016 188-214 / 79-105
PF01381.21 Helix-turn-helix 0.0012 188-212 / 8-32
PF16087.4 Domain of unknown function (DUF4817) 1.9E-05 2-41 / 5-52
PF10668.8 Phage terminase small subunit 0.0045 189-214 / 22-47
PF13011.5 leucine-zipper of insertion element IS481 0.0018 188-214 / 23-49
PF02954.18 Bacterial regulatory protein, Fis family 0.00084 188-212 / 15-39
PF13309.5 HTH domain 0.002 190-211 / 42-63
PF02042.14 RWP-RK domain 0.0033 188-214 / 11-37
PF04218.12 CENP-B N-terminal DNA-binding domain 0.0017 189-216 / 23-50
PF13518.5 Helix-turn-helix domain 0.0078 188-214 / 10-36
PF08765.10 Mor transcription activator family 0.00026 188-215 / 71-98
PF05225.15 helix-turn-helix, Psq domain 0.0056 188-214 / 15-42
PF14493.5 Helix-turn-helix domain 0.0042 188-214 / 11-37
PF04552.12 Sigma-54, DNA binding domain 0.0014 188-214 / 47-73
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.00065 174-212 / 88-130
PF17443.1 Uncharacterized protein pXO2-72 0.00071 188-210 / 7-29
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.0046 188-213 / 26-50
PF13411.5 MerR HTH family regulatory protein 0.0016 191-212 / 2-23
PF01527.19 Transposase 0.0078 188-214 / 20-46
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 0.0059 188-212 / 22-46
PF13413.5 Helix-turn-helix domain 0.0027 188-212 / 8-32
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.00073 188-216 / 54-82
PF13412.5 Winged helix-turn-helix DNA-binding 0.0029 188-215 / 16-43
PF02796.14 Helix-turn-helix domain of resolvase 0.00085 188-212 / 20-44
PF08535.9 KorB domain 0.0014 188-213 / 2-27
PF12116.7 Stage III sporulation protein D 0.0071 188-213 / 18-43
PF11112.7 Pyocin activator protein PrtN 0.0016 188-212 / 12-37
PF16677.4 DNA-packaging protein gp3 0.004 188-213 / 28-53
PF00376.22 MerR family regulatory protein 0.0016 192-212 / 2-22
PF13556.5 PucR C-terminal helix-turn-helix domain 0.0035 188-215 / 11-38
PF01371.18 Trp repressor protein 0.00024 5-39 / 41-74
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 0.0015 188-215 / 18-45
PF00356.20 Bacterial regulatory proteins, lacI family 0.001 191-212 / 1-22
PF07453.12 NUMOD1 domain 0.0011 189-210 / 19-40
PF06806.11 Putative excisionase (DUF1233) 0.0017 189-211 / 9-31
PF13936.5 Helix-turn-helix domain 0.0028 188-212 / 19-43
PF13551.5 Winged helix-turn helix 0.00045 5-41 / 4-39
PF13404.5 AsnC-type helix-turn-helix domain 0.0037 188-213 / 16-41
PF13591.5 MerR HTH family regulatory protein 0.0033 190-212 / 1-23
PF07278.10 Protein of unknown function (DUF1441) 0.0038 190-212 / 2-24
PF15978.4 Tn7-like transposition protein D 0.0006 4-40 / 194-230
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.0026 189-211 / 3-25
PF07825.10 Excisionase-like protein 0.0032 190-212 / 3-27
PF13744.5 Helix-turn-helix domain 0.00069 9-37 / 27-55
PF10975.7 Protein of unknown function (DUF2802) 0.00069 2-34 / 33-64
PF05331.10 Protein of unknown function (DUF742) 0.0014 188-214 / 52-78
PF11427.7 Tc3 transposase 0.0052 188-214 / 19-45
PF02650.13 WhiA C-terminal HTH domain 0.0076 12-38 / 53-81
PF11242.7 Protein of unknown function (DUF2774) 0.0074 188-214 / 13-39
PF07037.10 Putative transcription regulator (DUF1323) 0.0064 190-212 / 1-23
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0045 188-213 / 22-47
PF10743.8 Regulatory phage protein cox 0.0056 188-212 / 10-34
PF09035.9 Excisionase from transposon Tn916 0.0039 188-211 / 14-37
PF07638.10 ECF sigma factor 0.0014 188-216 / 148-176
PF13384.5 Homeodomain-like domain 0.0014 7-37 / 12-41
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0014 13-36 / 10-34
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.0024 189-212 / 51-74
PF05339.10 Protein of unknown function (DUF739) 0.0016 10-36 / 13-39
PF12964.6 Protein of unknown function (DUF3853) 0.0096 188-212 / 44-68
PF00440.22 Bacterial regulatory proteins, tetR family 0.0068 190-213 / 16-39
PF12728.6 Helix-turn-helix domain 0.0061 190-211 / 2-24
PF08281.11 Sigma-70, region 4 0.0047 188-215 / 25-52
PF16509.4 TrfB plasmid transcriptional repressor 0.0023 12-38 / 30-56
PF07471.11 Phage DNA packaging protein Nu1 0.0025 14-36 / 3-25
PF00325.19 Bacterial regulatory proteins, crp family 0.0026 14-38 / 3-27
PF07900.10 Protein of unknown function (DUF1670) 0.0027 12-41 / 94-123
PF13022.5 Helix-turn-helix of insertion element transposase 0.0027 14-35 / 26-47
PF07506.10 RepB plasmid partitioning protein 0.0028 12-37 / 20-45
PF08965.9 Domain of unknown function (DUF1870) 0.003 7-37 / 8-40
PF04545.15 Sigma-70, region 4 0.0061 188-215 / 23-50
PF14590.5 Domain of unknown function (DUF4447) 0.0032 8-37 / 15-44
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.0034 13-37 / 11-36
PF14549.5 DNA-binding transcriptional regulator Cro 0.0035 11-33 / 8-29
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.0036 8-39 / 7-37
PF03683.12 Uncharacterised protein family (UPF0175) 0.0034 4-40 / 20-56
PF04645.11 Protein of unknown function, DUF603 0.0035 5-37 / 12-47
PF06971.12 Putative DNA-binding protein N-terminus 0.01 189-210 / 27-48
PF12844.6 Helix-turn-helix domain 0.0042 12-36 / 11-35
PF07618.10 Protein of unknown function (DUF1580) 0.004 17-37 / 6-26
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.0043 11-36 / 7-30
PF04967.11 HTH DNA binding domain 0.0061 14-37 / 24-47
PF06413.10 Neugrin 0.0063 174-212 / 10-52
PF01022.19 Bacterial regulatory protein, arsR family 0.0051 12-38 / 15-41
PF00196.18 Bacterial regulatory proteins, luxR family 0.0075 13-38 / 17-42
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0049 11-36 / 124-149
PF05043.12 Mga helix-turn-helix domain 0.0072 11-39 / 28-56
PF08222.10 CodY helix-turn-helix domain 0.0059 189-214 / 4-29
PF12793.6 Sugar transport-related sRNA regulator N-term 0.0057 11-41 / 16-46
PF13693.5 Winged helix-turn-helix DNA-binding 0.0075 11-36 / 13-38
PF09012.9 FeoC like transcriptional regulator 0.0082 12-40 / 13-41
PF06530.11 Phage antitermination protein Q 0.0083 9-36 / 76-102
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.009 12-37 / 32-57
PF16221.4 winged helix-turn-helix 0.0093 189-215 / 46-72
PF00157.16 Pou domain - N-terminal to homeobox domain 0.0096 12-36 / 19-49
PF14056.5 Domain of unknown function (DUF4250) 0.0093 190-214 / 20-44

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein 1:HTH_Hin protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004803 transposase activity
GO:0043565 sequence-specific DNA binding
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0019069 viral capsid assembly
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0051775 response to redox state
GO:0006352 DNA-templated transcription, initiation
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0003700 DNA binding transcription factor activity
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0016987 sigma factor activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005622 intracellular

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