phrog_27344 is made of 3 protein sequences and is annotated as "replication initiation protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
347 347 347


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF919514_p56 ATN90250.1 HTH DNA binding protein MF919514 Gordonia phage Lennon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vividuovirus; Gordonia virus Lennon.
MG812487_p58 AUX81895.1 HTH DNA binding protein MG812487 Gordonia phage Brandonk123 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vividuovirus; Gordonia virus Brandonk123.
NC_031239_p60 YP_009301984.1 HTH DNA-binding protein NC_031239 Gordonia phage Vivi2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Vividuovirus; Gordonia virus Vivi2.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_27757 3 no annotation unknown function 3 0 1000
phrog_6055 20 no annotation unknown function 3 2.66E-18 8.7

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1032 replication initiation protein DNA, RNA and nucleotide metabolism 96.2 9.1E-05 17-90 / 15-88
phrog_10724 no annotation unknown function 92.5 0.019 40-72 / 31-63
phrog_13105 no annotation unknown function 90.9 0.044 38-77 / 17-56
phrog_1456 DNA binding protein DNA, RNA and nucleotide metabolism 92.7 0.017 38-82 / 10-54
phrog_15053 no annotation unknown function 94.3 0.0039 16-89 / 31-105
phrog_186 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 93.6 0.0078 17-77 / 24-87
phrog_1882 no annotation unknown function 94.1 0.0051 219-319 / 64-154
phrog_19658 replication initiation protein DNA, RNA and nucleotide metabolism 93.8 0.0065 15-80 / 15-78
phrog_2149 replication initiation protein DNA, RNA and nucleotide metabolism 98.6 2E-11 219-345 / 171-295
phrog_26369 replication initiation protein DNA, RNA and nucleotide metabolism 92.5 0.019 39-71 / 79-111
phrog_26991 no annotation unknown function 90.3 0.057 3-96 / 26-120
phrog_270 replication initiation protein DNA, RNA and nucleotide metabolism 96.5 2.8E-05 16-95 / 15-94
phrog_3502 no annotation unknown function 95.3 0.00091 16-71 / 3-57
phrog_391 replication initiation O-like DNA, RNA and nucleotide metabolism 97.0 3.8E-06 4-88 / 8-89
phrog_428 replication initiation protein DNA, RNA and nucleotide metabolism 93.1 0.012 41-76 / 49-84
phrog_4617 replication initiation protein DNA, RNA and nucleotide metabolism 92.8 0.015 18-76 / 15-74
phrog_6643 replication initiation protein DNA, RNA and nucleotide metabolism 90.4 0.055 4-88 / 8-86
phrog_678 replication initiation O-like DNA, RNA and nucleotide metabolism 96.6 2.1E-05 15-98 / 21-107
phrog_8102 replication initiation protein DNA, RNA and nucleotide metabolism 94.6 0.0025 14-85 / 18-89
phrog_9285 no annotation unknown function 96.8 9.6E-06 40-80 / 34-73
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 90.6 0.05 42-62 / 20-40

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04492.12 Bacteriophage replication protein O 0.00015 15-74 / 23-83
PF05584.10 Sulfolobus plasmid regulatory protein 0.00021 17-75 / 4-53
PF04358.12 DsrC like protein 0.00025 15-74 / 35-95
PF16221.4 winged helix-turn-helix 0.00032 20-72 / 32-78
PF01726.15 LexA DNA binding domain 0.00033 19-74 / 6-60
PF04079.15 Segregation and condensation complex subunit ScpB 0.00036 15-89 / 79-143
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.00045 39-74 / 22-57
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.00058 17-74 / 6-56
PF13463.5 Winged helix DNA-binding domain 0.00056 39-74 / 16-51
PF03965.15 Penicillinase repressor 0.0006 19-75 / 3-58
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.00063 17-75 / 7-69
PF13601.5 Winged helix DNA-binding domain 0.00062 39-75 / 13-49
PF14557.5 Putative AphA-like transcriptional regulator 0.00064 15-89 / 4-81
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.00068 17-73 / 11-60
PF03551.13 Transcriptional regulator PadR-like family 0.00083 39-75 / 13-51
PF12802.6 MarR family 0.0009 41-75 / 22-56
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.00099 15-64 / 16-75
PF08784.10 Replication protein A C terminal 0.0011 16-74 / 37-95
PF09114.9 Transcription factor MotA, activation domain 0.0012 15-73 / 12-64
PF09012.9 FeoC like transcriptional regulator 0.0012 40-75 / 14-49
PF05732.10 Firmicute plasmid replication protein (RepL) 0.0013 16-74 / 51-109
PF11313.7 Protein of unknown function (DUF3116) 0.0013 41-89 / 21-73
PF05158.11 RNA polymerase Rpc34 subunit 0.0014 16-75 / 89-143
PF02002.16 TFIIE alpha subunit 0.0014 20-75 / 13-61
PF01047.21 MarR family 0.0015 40-75 / 17-52
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0016 16-74 / 5-56
PF14394.5 Domain of unknown function (DUF4423) 0.0018 41-75 / 37-73
PF04182.11 B-block binding subunit of TFIIIC 0.0018 39-75 / 17-53
PF02295.16 Adenosine deaminase z-alpha domain 0.0021 40-74 / 18-53
PF01475.18 Ferric uptake regulator family 0.0021 16-75 / 4-62
PF13730.5 Helix-turn-helix domain 0.0021 17-70 / 3-52
PF03428.12 Replication protein C N-terminal domain 0.0022 15-75 / 39-106
PF14277.5 Domain of unknown function (DUF4364) 0.0022 39-73 / 14-52
PF01090.18 Ribosomal protein S19e 0.0024 39-75 / 64-115
PF02334.15 Replication terminator protein 0.0025 52-89 / 52-92
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.0027 23-75 / 5-53
PF12793.6 Sugar transport-related sRNA regulator N-term 0.003 39-74 / 17-52
PF07848.11 PaaX-like protein 0.0036 40-74 / 20-57
PF08222.10 CodY helix-turn-helix domain 0.0036 39-74 / 3-38
PF09639.9 YjcQ protein 0.0041 40-75 / 16-53
PF13412.5 Winged helix-turn-helix DNA-binding 0.0041 40-70 / 17-47
PF01638.16 HxlR-like helix-turn-helix 0.0042 39-75 / 18-55
PF09339.9 IclR helix-turn-helix domain 0.005 40-73 / 18-51
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.0055 39-74 / 23-58
PF01022.19 Bacterial regulatory protein, arsR family 0.0057 40-70 / 16-46
PF09202.10 Rio2, N-terminal 0.0059 17-74 / 4-58
PF06163.10 Bacterial protein of unknown function (DUF977) 0.0067 39-74 / 25-60

Annotations of the NCBI proteins of this PHROG


2:HTH DNA binding protein 1:HTH DNA-binding protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0006383 transcription by RNA polymerase III
GO:0006260 DNA replication
GO:0004674 protein serine/threonine kinase activity
GO:0007131 reciprocal meiotic recombination
GO:0006468 protein phosphorylation
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0003677 DNA binding
GO:0003700 DNA binding transcription factor activity
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0004252 serine-type endopeptidase activity
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0051304 chromosome separation
GO:0006355 regulation of transcription, DNA-templated
GO:0006412 translation
GO:0005666 DNA-directed RNA polymerase III complex
GO:0006508 proteolysis
GO:0006276 plasmid maintenance
GO:0005524 ATP binding

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