phrog_27829 is made of 3 protein sequences and is annotated as "DnaA-like replication initiation protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
72 72 72


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_019446_p33 YP_007002041.1 putative replication initiation factor NC_019446 Brucella phage Tb Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Perisivirus.
HG428758_p28 CDL18779.1 putative replication initiation protein HG428758 Brucella phage F1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Perisivirus; Brucella virus Tb.
NC_019447_p32 YP_007002098.1 putative DnaA-like protein NC_019447 Brucella phage Pr Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Perisivirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_23381 3 no annotation unknown function 3 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
no PHROGs similar                                                                           

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF08299.10 Bacterial dnaA protein helix-turn-helix 4.5E-15 2-67 / 2-68
PF05331.10 Protein of unknown function (DUF742) 2.8E-06 43-72 / 52-81
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 4.4E-06 42-70 / 11-39
PF05344.10 Domain of Unknown Function (DUF746) 1.8E-05 43-70 / 11-38
PF00292.17 'Paired box' domain 1.9E-05 42-70 / 31-59
PF03333.12 Adhesin biosynthesis transcription regulatory protein 2E-05 41-70 / 52-81
PF08535.9 KorB domain 2.4E-05 44-69 / 3-28
PF09012.9 FeoC like transcriptional regulator 2.4E-05 42-72 / 12-42
PF08822.10 Protein of unknown function (DUF1804) 2.5E-05 43-70 / 18-45
PF07638.10 ECF sigma factor 2.7E-05 39-69 / 144-174
PF13412.5 Winged helix-turn-helix DNA-binding 3.1E-05 43-72 / 16-45
PF02319.19 E2F/DP family winged-helix DNA-binding domain 3.6E-05 42-72 / 21-51
PF16221.4 winged helix-turn-helix 4.1E-05 44-72 / 46-74
PF13011.5 leucine-zipper of insertion element IS481 4.4E-05 42-70 / 22-50
PF12793.6 Sugar transport-related sRNA regulator N-term 5E-05 41-72 / 15-46
PF08222.10 CodY helix-turn-helix domain 5.1E-05 44-70 / 4-30
PF14493.5 Helix-turn-helix domain 5.8E-05 42-70 / 10-38
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 6.2E-05 43-70 / 18-45
PF04492.12 Bacteriophage replication protein O 6.9E-05 44-72 / 49-77
PF04936.11 Protein of unknown function (DUF658) 0.0027 43-68 / 87-112
PF07141.10 Putative bacteriophage terminase small subunit 7.8E-05 42-69 / 29-56
PF13518.5 Helix-turn-helix domain 8.8E-05 43-71 / 10-38
PF06322.10 Phage NinH protein 9.1E-05 43-69 / 15-41
PF10654.8 Protein of unknown function (DUF2481) 8.5E-05 42-67 / 78-103
PF04552.12 Sigma-54, DNA binding domain 9.3E-05 41-69 / 45-73
PF12759.6 InsA C-terminal domain 0.0001 42-68 / 19-45
PF02954.18 Bacterial regulatory protein, Fis family 0.0001 43-67 / 15-39
PF00325.19 Bacterial regulatory proteins, crp family 0.00011 46-69 / 4-27
PF01022.19 Bacterial regulatory protein, arsR family 0.00012 43-72 / 15-44
PF11427.7 Tc3 transposase 0.00012 43-71 / 19-47
PF01710.15 Transposase 0.00013 42-69 / 16-43
PF13601.5 Winged helix DNA-binding domain 0.00014 44-70 / 14-40
PF05225.15 helix-turn-helix, Psq domain 0.00015 42-69 / 14-42
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.00016 43-72 / 21-50
PF08765.10 Mor transcription activator family 0.00016 43-70 / 71-98
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.00018 42-72 / 25-55
PF13404.5 AsnC-type helix-turn-helix domain 0.00021 43-68 / 16-41
PF07900.10 Protein of unknown function (DUF1670) 0.00022 42-72 / 93-123
PF07453.12 NUMOD1 domain 0.00022 44-64 / 19-39
PF11242.7 Protein of unknown function (DUF2774) 0.00023 42-70 / 12-40
PF09607.9 Brinker DNA-binding domain 0.00024 45-70 / 26-51
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.00023 42-66 / 22-46
PF08279.11 HTH domain 0.00025 43-70 / 14-41
PF10668.8 Phage terminase small subunit 0.00025 44-70 / 22-48
PF02650.13 WhiA C-terminal HTH domain 0.00024 37-70 / 47-82
PF06627.10 Protein of unknown function (DUF1153) 0.00026 43-71 / 45-73
PF04218.12 CENP-B N-terminal DNA-binding domain 0.00029 44-69 / 23-48
PF04545.15 Sigma-70, region 4 0.00029 43-68 / 23-48
PF17443.1 Uncharacterized protein pXO2-72 0.00029 43-65 / 7-29
PF13551.5 Winged helix-turn helix 0.00031 44-69 / 11-36
PF13556.5 PucR C-terminal helix-turn-helix domain 0.00032 43-70 / 11-38
PF08281.11 Sigma-70, region 4 0.00033 42-69 / 24-51
PF15977.4 Winged helix-turn-helix DNA binding 0.00034 44-71 / 23-50
PF01381.21 Helix-turn-helix 0.00035 42-67 / 7-32
PF01371.18 Trp repressor protein 0.00035 41-70 / 45-74
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.00035 46-67 / 53-74
PF09904.8 Winged helix-turn helix 0.00036 42-70 / 19-47
PF12802.6 MarR family 0.00039 45-71 / 22-48
PF05732.10 Firmicute plasmid replication protein (RepL) 0.00037 43-72 / 74-103
PF09339.9 IclR helix-turn-helix domain 0.00039 45-71 / 19-45
PF13411.5 MerR HTH family regulatory protein 0.00041 46-67 / 2-23
PF05584.10 Sulfolobus plasmid regulatory protein 0.00041 42-71 / 16-45
PF06163.10 Bacterial protein of unknown function (DUF977) 0.00044 42-72 / 24-54
PF02082.19 Transcriptional regulator 0.00047 45-71 / 25-51
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00049 45-70 / 12-37
PF16509.4 TrfB plasmid transcriptional repressor 0.00052 42-69 / 29-56
PF01047.21 MarR family 0.00053 44-70 / 17-43
PF02796.14 Helix-turn-helix domain of resolvase 0.00056 43-66 / 20-43
PF02042.14 RWP-RK domain 0.00055 42-68 / 10-36
PF07278.10 Protein of unknown function (DUF1441) 0.00054 45-67 / 2-24
PF13413.5 Helix-turn-helix domain 0.00056 43-66 / 8-31
PF01527.19 Transposase 0.00063 42-69 / 19-46
PF00376.22 MerR family regulatory protein 0.00063 48-66 / 3-21
PF02002.16 TFIIE alpha subunit 0.00063 42-72 / 24-54
PF07037.10 Putative transcription regulator (DUF1323) 0.00063 46-67 / 2-23
PF14947.5 Winged helix-turn-helix 0.00064 44-70 / 16-42
PF06530.11 Phage antitermination protein Q 0.00063 39-68 / 74-103
PF09182.9 Bacterial purine repressor, N-terminal 0.00066 42-70 / 18-46
PF13591.5 MerR HTH family regulatory protein 0.00066 46-67 / 2-23
PF13463.5 Winged helix DNA-binding domain 0.0007 44-70 / 17-43
PF01418.16 Helix-turn-helix domain, rpiR family 0.00069 44-70 / 34-60
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.00072 45-66 / 4-25
PF15978.4 Tn7-like transposition protein D 0.00071 43-69 / 202-228
PF00356.20 Bacterial regulatory proteins, lacI family 0.00074 47-66 / 2-21
PF13936.5 Helix-turn-helix domain 0.0008 42-66 / 18-42
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.00097 43-71 / 21-49
PF00392.20 Bacterial regulatory proteins, gntR family 0.00098 43-71 / 22-51
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.001 42-68 / 31-57
PF04703.11 FaeA-like protein 0.0011 44-68 / 14-38
PF04967.11 HTH DNA binding domain 0.0011 44-69 / 23-48
PF06806.11 Putative excisionase (DUF1233) 0.0011 44-66 / 9-31
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0012 43-70 / 16-43
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 0.0012 40-65 / 19-44
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.0013 46-68 / 28-50
PF04182.11 B-block binding subunit of TFIIIC 0.0013 44-71 / 18-45
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0014 43-71 / 20-48
PF11994.7 Protein of unknown function (DUF3489) 0.0013 36-70 / 13-47
PF05158.11 RNA polymerase Rpc34 subunit 0.0014 42-72 / 106-136
PF05043.12 Mga helix-turn-helix domain 0.0015 42-70 / 28-56
PF13545.5 Crp-like helix-turn-helix domain 0.0016 43-71 / 26-54
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.0015 44-67 / 107-130
PF13309.5 HTH domain 0.0016 45-65 / 42-62
PF07374.10 Protein of unknown function (DUF1492) 0.0018 41-69 / 68-96
PF10743.8 Regulatory phage protein cox 0.0018 43-67 / 10-34
PF16264.4 SatD family (SatD) 0.0019 43-68 / 170-195
PF09824.8 ArsR transcriptional regulator 0.0019 42-72 / 28-56
PF09035.9 Excisionase from transposon Tn916 0.0021 43-65 / 14-36
PF04079.15 Segregation and condensation complex subunit ScpB 0.002 39-72 / 92-122
PF07471.11 Phage DNA packaging protein Nu1 0.0022 45-67 / 3-25
PF14502.5 Helix-turn-helix domain 0.0023 49-65 / 11-27
PF02001.15 Protein of unknown function DUF134 0.0022 42-68 / 45-71
PF07506.10 RepB plasmid partitioning protein 0.0022 43-68 / 20-45
PF12728.6 Helix-turn-helix domain 0.0024 46-65 / 3-23
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.0026 43-69 / 19-45
PF12116.7 Stage III sporulation protein D 0.0027 43-67 / 18-42
PF10975.7 Protein of unknown function (DUF2802) 0.0026 39-65 / 38-64
PF08220.11 DeoR-like helix-turn-helix domain 0.0033 45-69 / 15-39
PF06971.12 Putative DNA-binding protein N-terminus 0.0032 44-65 / 27-48
PF00196.18 Bacterial regulatory proteins, luxR family 0.0035 43-69 / 16-42
PF13384.5 Homeodomain-like domain 0.0036 44-68 / 17-41
PF09202.10 Rio2, N-terminal 0.0037 44-70 / 24-50
PF09048.9 Cro 0.0038 44-67 / 13-36
PF12964.6 Protein of unknown function (DUF3853) 0.0039 43-67 / 44-68
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0053 46-64 / 13-31
PF16677.4 DNA-packaging protein gp3 0.0057 43-68 / 28-53
PF03297.14 S25 ribosomal protein 0.0057 43-71 / 55-83
PF00440.22 Bacterial regulatory proteins, tetR family 0.0064 45-68 / 16-39
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.0066 45-69 / 25-49
PF14549.5 DNA-binding transcriptional regulator Cro 0.0066 46-63 / 11-28
PF16864.4 Dimerisation domain 0.0071 43-70 / 31-58
PF05339.10 Protein of unknown function (DUF739) 0.0084 44-64 / 16-36
PF13744.5 Helix-turn-helix domain 0.01 42-66 / 29-53
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.0096 42-70 / 20-48

Annotations of the NCBI proteins of this PHROG


1:replication initiation protein 1:DnaA-like protein 1:replication initiation factor

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0019069 viral capsid assembly
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0051304 chromosome separation
GO:0051775 response to redox state
GO:0006352 DNA-templated transcription, initiation
GO:0004803 transposase activity
GO:0005666 DNA-directed RNA polymerase III complex
GO:0043565 sequence-specific DNA binding
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0006270 DNA replication initiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0016987 sigma factor activity
GO:0004674 protein serine/threonine kinase activity
GO:0005622 intracellular
GO:0006383 transcription by RNA polymerase III
GO:0009289 pilus
GO:0006260 DNA replication
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0006468 protein phosphorylation
GO:0006275 regulation of DNA replication
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0003700 DNA binding transcription factor activity

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