phrog_28010 is made of 2 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
63 63 63


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_031052_p51 YP_009284822.1 HTH DNA binding protein NC_031052 Gordonia phage Twister6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wizardvirus.
NC_030913_p48 YP_009274087.1 HTH DNA binding domain protein NC_030913 Gordonia phage Wizard Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wizardvirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_28820 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_6401 DNA binding protein DNA, RNA and nucleotide metabolism 91.4 0.036 17-60 / 18-61
phrog_7506 recombination directionality factor integration and excision 92.6 0.017 8-48 / 14-53

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF11112.7 Pyocin activator protein PrtN 1.9E-10 7-59 / 12-70
PF12964.6 Protein of unknown function (DUF3853) 1.3E-09 7-56 / 44-94
PF10743.8 Regulatory phage protein cox 1.6E-09 6-58 / 9-66
PF09035.9 Excisionase from transposon Tn916 2.5E-09 7-57 / 14-65
PF13591.5 MerR HTH family regulatory protein 5.7E-09 9-51 / 1-42
PF06806.11 Putative excisionase (DUF1233) 7.6E-09 6-57 / 7-68
PF12728.6 Helix-turn-helix domain 9.5E-09 9-56 / 2-49
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 1.4E-08 8-35 / 3-31
PF07825.10 Excisionase-like protein 1.4E-08 9-50 / 3-47
PF13411.5 MerR HTH family regulatory protein 2E-08 10-37 / 2-29
PF07278.10 Protein of unknown function (DUF1441) 2E-08 8-33 / 1-26
PF07618.10 Protein of unknown function (DUF1580) 2.7E-08 13-57 / 7-55
PF07471.11 Phage DNA packaging protein Nu1 3.6E-08 8-36 / 2-29
PF07750.10 GcrA cell cycle regulator 1.2E-07 3-33 / 13-44
PF04936.11 Protein of unknown function (DUF658) 1.2E-05 7-36 / 87-116
PF07141.10 Putative bacteriophage terminase small subunit 1.4E-07 5-31 / 28-54
PF17443.1 Uncharacterized protein pXO2-72 1.8E-07 6-33 / 6-33
PF01710.15 Transposase 0.0019 7-35 / 69-97
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 5.5E-07 5-32 / 10-37
PF10654.8 Protein of unknown function (DUF2481) 5.2E-07 6-31 / 78-103
PF08765.10 Mor transcription activator family 9.6E-07 7-32 / 71-96
PF00292.17 'Paired box' domain 1.5E-06 5-31 / 30-56
PF00376.22 MerR family regulatory protein 1.5E-06 11-34 / 2-25
PF08822.10 Protein of unknown function (DUF1804) 1.8E-06 7-31 / 18-42
PF12759.6 InsA C-terminal domain 1.8E-06 6-31 / 19-44
PF05344.10 Domain of Unknown Function (DUF746) 1.8E-06 6-31 / 10-35
PF04552.12 Sigma-54, DNA binding domain 3E-06 6-32 / 46-72
PF10975.7 Protein of unknown function (DUF2802) 3.7E-06 2-29 / 37-64
PF07453.12 NUMOD1 domain 4.1E-06 7-28 / 18-39
PF09607.9 Brinker DNA-binding domain 4.3E-06 9-31 / 26-48
PF01381.21 Helix-turn-helix 4.8E-06 6-31 / 7-32
PF14493.5 Helix-turn-helix domain 5E-06 5-31 / 9-35
PF08535.9 KorB domain 5.3E-06 7-31 / 2-26
PF02796.14 Helix-turn-helix domain of resolvase 8.9E-06 7-30 / 20-43
PF00356.20 Bacterial regulatory proteins, lacI family 9.2E-06 10-32 / 1-23
PF06322.10 Phage NinH protein 9.6E-06 7-33 / 15-41
PF02954.18 Bacterial regulatory protein, Fis family 1.1E-05 7-30 / 15-38
PF08876.10 Domain of unknown function (DUF1836) 1.2E-05 7-37 / 9-49
PF13309.5 HTH domain 1.3E-05 9-29 / 42-62
PF06970.10 Replication initiator protein A (RepA) N-terminus 1.3E-05 10-30 / 53-73
PF02319.19 E2F/DP family winged-helix DNA-binding domain 1.3E-05 7-31 / 22-46
PF15978.4 Tn7-like transposition protein D 1.5E-05 7-31 / 202-226
PF12824.6 Mitochondrial ribosomal protein subunit L20 1.4E-05 8-31 / 107-130
PF13542.5 Helix-turn-helix domain of transposase family ISL3 1.6E-05 10-31 / 28-49
PF13413.5 Helix-turn-helix domain 1.5E-05 6-31 / 7-32
PF03333.12 Adhesin biosynthesis transcription regulatory protein 1.5E-05 6-31 / 53-78
PF13011.5 leucine-zipper of insertion element IS481 1.6E-05 6-31 / 22-47
PF13936.5 Helix-turn-helix domain 1.8E-05 7-30 / 19-42
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 2.3E-05 7-31 / 18-42
PF07638.10 ECF sigma factor 2.5E-05 6-31 / 147-172
PF07037.10 Putative transcription regulator (DUF1323) 2.5E-05 9-31 / 1-23
PF10668.8 Phage terminase small subunit 2.6E-05 8-32 / 22-46
PF04218.12 CENP-B N-terminal DNA-binding domain 3E-05 9-31 / 24-46
PF05331.10 Protein of unknown function (DUF742) 2.8E-05 7-31 / 52-76
PF16677.4 DNA-packaging protein gp3 3.7E-05 7-32 / 28-53
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 4.2E-05 6-32 / 21-47
PF11242.7 Protein of unknown function (DUF2774) 4.5E-05 5-31 / 11-37
PF02042.14 RWP-RK domain 5.3E-05 6-32 / 10-36
PF07506.10 RepB plasmid partitioning protein 5.3E-05 5-32 / 18-45
PF11427.7 Tc3 transposase 5.8E-05 7-31 / 19-43
PF13518.5 Helix-turn-helix domain 6E-05 7-31 / 10-34
PF13412.5 Winged helix-turn-helix DNA-binding 6.1E-05 8-31 / 17-40
PF06971.12 Putative DNA-binding protein N-terminus 6.1E-05 8-29 / 27-48
PF08004.10 Protein of unknown function (DUF1699) 6E-05 3-29 / 99-129
PF13404.5 AsnC-type helix-turn-helix domain 7E-05 7-30 / 16-39
PF13556.5 PucR C-terminal helix-turn-helix domain 6.9E-05 7-31 / 11-35
PF01371.18 Trp repressor protein 6.9E-05 5-32 / 45-72
PF08222.10 CodY helix-turn-helix domain 7.1E-05 7-31 / 3-27
PF12116.7 Stage III sporulation protein D 7.2E-05 7-32 / 18-43
PF06627.10 Protein of unknown function (DUF1153) 7.3E-05 7-31 / 45-69
PF05225.15 helix-turn-helix, Psq domain 9.1E-05 7-31 / 15-40
PF00440.22 Bacterial regulatory proteins, tetR family 0.00011 9-31 / 16-38
PF16701.4 Adenylate cyclase regulatory domain 0.00013 8-35 / 58-86
PF16509.4 TrfB plasmid transcriptional repressor 0.00014 7-31 / 30-54
PF13551.5 Winged helix-turn helix 0.00014 6-31 / 9-34
PF13384.5 Homeodomain-like domain 0.00015 7-31 / 16-40
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00015 8-31 / 11-34
PF13022.5 Helix-turn-helix of insertion element transposase 0.00016 8-32 / 25-49
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.00017 7-31 / 9-34
PF08281.11 Sigma-70, region 4 0.00019 7-31 / 25-49
PF00325.19 Bacterial regulatory proteins, crp family 0.00019 9-30 / 3-24
PF01527.19 Transposase 0.0002 6-33 / 19-46
PF08279.11 HTH domain 0.00021 7-31 / 14-38
PF09182.9 Bacterial purine repressor, N-terminal 0.00025 7-31 / 19-43
PF06413.10 Neugrin 0.00023 8-31 / 29-52
PF04967.11 HTH DNA binding domain 0.00026 9-31 / 24-46
PF00196.18 Bacterial regulatory proteins, luxR family 0.00026 6-31 / 15-40
PF16221.4 winged helix-turn-helix 0.00026 8-31 / 46-69
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00027 6-31 / 16-41
PF04545.15 Sigma-70, region 4 0.00027 7-31 / 23-47
PF05043.12 Mga helix-turn-helix domain 0.00028 7-31 / 29-53
PF05339.10 Protein of unknown function (DUF739) 0.0003 7-31 / 15-39
PF06530.11 Phage antitermination protein Q 0.00034 6-31 / 77-102
PF03683.12 Uncharacterised protein family (UPF0175) 0.00034 4-35 / 24-56
PF04492.12 Bacteriophage replication protein O 0.00042 8-31 / 49-72
PF09012.9 FeoC like transcriptional regulator 0.00045 7-31 / 13-37
PF13744.5 Helix-turn-helix domain 0.00048 7-31 / 30-54
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.00051 9-29 / 9-29
PF13171.5 Protein of unknown function (DUF4004) 0.00047 9-35 / 3-29
PF12844.6 Helix-turn-helix domain 0.00054 7-31 / 11-35
PF01022.19 Bacterial regulatory protein, arsR family 0.00055 8-31 / 16-39
PF12802.6 MarR family 0.00055 9-31 / 22-44
PF14549.5 DNA-binding transcriptional regulator Cro 0.00054 7-28 / 9-29
PF01418.16 Helix-turn-helix domain, rpiR family 0.00057 8-31 / 34-57
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.00065 8-32 / 11-36
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.00067 7-31 / 19-43
PF07374.10 Protein of unknown function (DUF1492) 0.0007 6-31 / 69-94
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.00074 6-30 / 22-46
PF16264.4 SatD family (SatD) 0.00076 7-32 / 170-195
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.00086 6-31 / 31-56
PF07900.10 Protein of unknown function (DUF1670) 0.00097 6-31 / 93-118
PF02001.15 Protein of unknown function DUF134 0.00099 6-31 / 45-70
PF09339.9 IclR helix-turn-helix domain 0.0011 9-31 / 19-41
PF14056.5 Domain of unknown function (DUF4250) 0.001 9-34 / 20-45
PF14590.5 Domain of unknown function (DUF4447) 0.0011 7-31 / 19-43
PF05269.10 Bacteriophage CII protein 0.0013 7-31 / 22-46
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.0013 7-31 / 26-50
PF09862.8 Protein of unknown function (DUF2089) 0.0014 7-31 / 48-72
PF09904.8 Winged helix-turn helix 0.0013 7-31 / 20-44
PF09048.9 Cro 0.0016 7-31 / 12-36
PF13693.5 Winged helix-turn-helix DNA-binding 0.0016 7-31 / 14-38
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.0015 8-31 / 22-45
PF11972.7 HTH DNA binding domain 0.0016 7-32 / 12-37
PF00392.20 Bacterial regulatory proteins, gntR family 0.0017 10-31 / 26-47
PF02082.19 Transcriptional regulator 0.0017 9-31 / 25-47
PF15977.4 Winged helix-turn-helix DNA binding 0.0018 8-31 / 23-46
PF13560.5 Helix-turn-helix domain 0.0018 7-31 / 13-37
PF04645.11 Protein of unknown function, DUF603 0.0017 7-31 / 18-46
PF05584.10 Sulfolobus plasmid regulatory protein 0.0019 7-31 / 17-41
PF13601.5 Winged helix DNA-binding domain 0.002 7-31 / 13-37
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.0023 7-32 / 81-106
PF13463.5 Winged helix DNA-binding domain 0.0026 8-31 / 17-40
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0027 7-31 / 125-149
PF06892.10 Phage regulatory protein CII (CP76) 0.0027 10-31 / 21-42
PF14947.5 Winged helix-turn-helix 0.0029 7-31 / 15-39
PF14502.5 Helix-turn-helix domain 0.0033 7-31 / 5-29
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0034 7-31 / 20-44
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0034 7-31 / 16-40
PF04182.11 B-block binding subunit of TFIIIC 0.0035 7-31 / 17-41
PF04703.11 FaeA-like protein 0.0038 7-31 / 13-37
PF05732.10 Firmicute plasmid replication protein (RepL) 0.0039 8-31 / 75-98
PF01047.21 MarR family 0.0045 8-31 / 17-40
PF13545.5 Crp-like helix-turn-helix domain 0.0046 7-31 / 26-50
PF06353.11 Protein of unknown function (DUF1062) 0.0045 12-35 / 110-133
PF14210.5 Domain of unknown function (DUF4322) 0.0044 12-29 / 47-64
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0055 7-31 / 21-45
PF06163.10 Bacterial protein of unknown function (DUF977) 0.0056 7-31 / 25-49
PF07768.10 PVL ORF-50-like family 0.0058 7-32 / 7-36
PF08220.11 DeoR-like helix-turn-helix domain 0.0065 8-31 / 14-37
PF02002.16 TFIIE alpha subunit 0.0065 7-31 / 25-49

Annotations of the NCBI proteins of this PHROG


1:HTH DNA binding protein 1:HTH DNA binding domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0003700 DNA binding transcription factor activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0005622 intracellular
GO:0009289 pilus
GO:0045893 positive regulation of transcription, DNA-templated
GO:0006260 DNA replication
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0016987 sigma factor activity
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0004803 transposase activity
GO:0043565 sequence-specific DNA binding
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0051775 response to redox state
GO:0006352 DNA-templated transcription, initiation
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0019069 viral capsid assembly

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