phrog_2914 is made of 49 protein sequences and is annotated as "endonuclease VII"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
123.76 296 100


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_022751_p30 YP_008766988.1 recombination endonuclease VII NC_022751 Cyanophage PP Viruses; Caudovirales; Podoviridae.
KM224878_p53 AII27097.1 putative endonuclease KM224878 Vibrio phage ICP2_2011_A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
HQ641346_p47 ADX87801.1 hypothetical protein HQ641346 Vibrio phage ICP2_2006_A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
KY630187_p3 AQW88528.1 hypothetical protein KY630187 Serratia phage BF Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Eneladusvirus; Serratia virus BF.
NC_011534_p43 YP_002308424.1 hypothetical protein NC_011534 Kluyvera phage Kvp1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Berlinvirus.
NC_030917_p119 YP_009274544.1 EndoVII NC_030917 Gordonia phage OneUp Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Oneupvirus.
JN699628_p77 AER26120.1 endonuclease VII JN699628 Mycobacterium phage Bongo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mclasvirinae; Bongovirus; Mycobacterium virus Bongo.
MF668284_p160 ASZ74236.1 endonuclease VII MF668284 Mycobacterium phage Squint Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_021299_p76 YP_008051008.1 hypothetical protein NC_021299 Mycobacterium phage PegLeg Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mclasvirinae; Bongovirus; unclassified Bongovirus.
NC_011292_p6 YP_002242063.1 gp6 NC_011292 Mycobacterium phage Konstantine Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Barnyardvirus.
KU886269_p45 ANH49309.1 recombination endonuclease VII KU886269 Freshwater phage uvFW-CGR-AMD-COM-C403 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
NC_019402_p33 YP_006987680.1 endonuclease VII NC_019402 Cronobacter phage vB_CsaP_GAP52 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
KY084243_p39 APD19651.1 hypothetical protein KY084243 Pectobacterium phage PP74 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Berlinvirus; Pectobacterium virus PP74.
NC_013651_p16 YP_003347916.1 putative 13.5 kDa protein NC_013651 Vibrio phage N4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Chatterjeevirus; Vibrio virus N4.
NC_015158_p53 YP_004251224.1 putative endonuclease NC_015158 Vibrio phage ICP2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.
KY883658_p56 ASV43846.1 endonuclease VII KY883658 Vibrio phage JSF27 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
KU183006_p38 ALT58493.1 endonuclease VII KU183006 Klebsiella phage vB_KpnP_IME205 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Przondovirus; Klebsiella virus IME205.
KT591491_p75 ALF00603.1 endonuclease VII KT591491 Mycobacterium phage Bricole Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mclasvirinae; Bongovirus; unclassified Bongovirus.
NC_027337_p93 YP_009147362.1 endonuclease VII NC_027337 Escherichia phage vB_EcoM-VpaE1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus.
NC_004664_p32 NP_813723.1 gp7 NC_004664 Streptomyces virus phiBT1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lomovskayavirus.
NC_018853_p29 YP_006907205.1 putative HNH endonuclease NC_018853 Streptomyce phage TG1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tigunavirus.
NC_001978_p32 NP_047953.1 gp7 NC_001978 Streptomyces virus phiC31 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lomovskayavirus.
p16919 no NCBI prot ID no annotation VI_06221 Deinococci_gi_484153811 Viruses.
NC_019510_p36 YP_007005460.1 gp13.5 NC_019510 Erwinia phage vB_EamP-L1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Studiervirinae; Elunavirus; Erwinia virus L1.
MH045566_p31 AVR56697.1 HNH endonuclease MH045566 Microbacterium phage Didgeridoo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dismasvirus; unclassified Dismasvirus.
NC_031060_p66 YP_009286010.1 endonuclease VII NC_031060 Gordonia phage JSwag Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Soupsvirus; unclassified Soupsvirus.
NC_031031_p67 YP_009281681.1 endonuclease VII NC_031031 Gordonia phage Remus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Soupsvirus; unclassified Soupsvirus.
MF668282_p67 ASZ73946.1 endonuclease VII MF668282 Gordonia phage ShayRa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Soupsvirus; unclassified Soupsvirus.
NC_016653_p43 YP_005087169.1 endonuclease 7 NC_016653 Rhodococcus phage RER2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rerduovirus.
MF324902_p48 ASR84431.1 endonuclease VII MF324902 Rhodococcus phage Krishelle Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rerduovirus; unclassified Rerduovirus.
MF189179_p47 ASR80847.1 endonuclease VII MF189179 Rhodococcus phage Yoncess Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rerduovirus; unclassified Rerduovirus.
KY549154_p48 AQP30978.1 endonuclease VII KY549154 Rhodococcus phage BobbyDazzler Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rerduovirus; unclassified Rerduovirus.
MF141539_p58 ASR77165.1 endonuclease VII MF141539 Mycobacterium phage MyraDee Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Fromanvirus; unclassified Fromanvirus.
JF957059_p81 AEJ92139.1 endonuclease VII domain protein JF957059 Mycobacterium virus Optimus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
JF937090_p88 AEK08145.1 endonuclease VII JF937090 Mycobacterium virus Baka Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_004688_p87 NP_818388.1 gp89 NC_004688 Mycobacterium virus Omega Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
JF937101_p84 AEK09467.1 endonuclease VII JF937101 Mycobacterium virus Littlee Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus.
NC_026584_p86 YP_009124039.1 endonuclease VII NC_026584 Mycobacterium phage Minerva Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Omegavirus; unclassified Omegavirus.
NC_010325_p35 YP_001671908.1 endonuclease NC_010325 Pseudomonas phage LUZ24 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Bruynoghevirus.
NC_023583_p32 YP_009007824.1 endonuclease NC_023583 Pseudomonas phage TL Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Bruynoghevirus.
NC_030917_p27 YP_009274452.1 EndoVII NC_030917 Gordonia phage OneUp Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Oneupvirus.
MG515223_p2 ATW62459.1 endonuclease VII MG515223 Streptomyces phage WRightOn Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
p261640 no NCBI prot ID no annotation VI_00040 Actinobacteria_gi_483969925 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_011039_p10 YP_002003368.1 gp10 NC_011039 Mycobacterium phage Predator Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Barnyardvirus.
NC_016655_p82 YP_005087334.1 recombination endonuclease NC_016655 Rhodococcus phage REQ1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_009554_p42 YP_001285917.1 hypothetical protein NC_009554 Lactobacillus phage LL-H Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_021305_p22 YP_008051501.1 HNH endonuclease NC_021305 Mycobacterium phage Murphy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Kostyavirus; unclassified Kostyavirus.
p56675 no NCBI prot ID no annotation VI_04169 Actinobacteria_gi_483400703_10663_64185 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_023703_p2 YP_009013552.1 gp2 NC_023703 Mycobacterium phage Dori Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_7416 16 no annotation unknown function 4 4.36E-17 7.48
phrog_18140 5 no annotation unknown function 4 9.99E-21 11.12
phrog_7531 16 no annotation unknown function 4 4.36E-17 7.48
phrog_13833 7 membrane protein moron, auxiliary metabolic gene and host takeover 3 3.58E-15 5.57
phrog_6088 20 DNA primase DNA, RNA and nucleotide metabolism 3 4.95E-13 3.43
phrog_11257 9 no annotation unknown function 3 1.29E-14 5.01
phrog_16095 6 no annotation unknown function 3 1.53E-15 5.94
phrog_6736 18 no annotation unknown function 3 3.12E-13 3.63
phrog_6187 20 no annotation unknown function 3 4.95E-13 3.43
phrog_24147 3 DNA polymerase DNA, RNA and nucleotide metabolism 2 1.03E-12 3.11
phrog_15072 6 no annotation unknown function 2 2.07E-11 1.81

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 98.6 5.2E-11 20-93 / 83-165
phrog_10378 HNH endonuclease DNA, RNA and nucleotide metabolism 90.7 0.049 29-79 / 96-151
phrog_10822 HNH endonuclease DNA, RNA and nucleotide metabolism 90.8 0.047 38-76 / 99-144
phrog_11865 endonuclease VII DNA, RNA and nucleotide metabolism 98.0 5.9E-09 56-97 / 1-56
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00041 22-82 / 130-201
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 93.1 0.013 26-81 / 4-64
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 93.8 0.0068 31-83 / 55-115
phrog_14729 no annotation unknown function 94.2 0.0046 30-78 / 18-86
phrog_16016 HNH endonuclease DNA, RNA and nucleotide metabolism 94.5 0.0029 31-80 / 41-99
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 93.4 0.01 30-85 / 72-134
phrog_16986 no annotation unknown function 95.6 0.00048 23-80 / 5-67
phrog_17507 endonuclease VII DNA, RNA and nucleotide metabolism 99.2 1.2E-14 57-99 / 1-44
phrog_1985 HNH endonuclease DNA, RNA and nucleotide metabolism 92.3 0.021 35-83 / 64-130
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 98.0 7.6E-09 24-81 / 2-74
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.5E-06 31-81 / 28-80
phrog_2633 endonuclease VII DNA, RNA and nucleotide metabolism 100.0 2.9E-37 14-98 / 53-134
phrog_307 endonuclease VII DNA, RNA and nucleotide metabolism 100.0 2.3E-36 3-100 / 40-137
phrog_3106 HNH endonuclease DNA, RNA and nucleotide metabolism 94.6 0.0026 28-86 / 32-111
phrog_33554 HNH endonuclease DNA, RNA and nucleotide metabolism 91.9 0.027 31-86 / 12-80
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 0.0001 34-84 / 24-86
phrog_36860 HNH endonuclease DNA, RNA and nucleotide metabolism 97.1 2.3E-06 27-97 / 25-110
phrog_37301 no annotation unknown function 93.5 0.0087 52-78 / 10-36
phrog_423 endonuclease VII DNA, RNA and nucleotide metabolism 99.6 2.8E-20 31-97 / 14-94
phrog_4581 terminase small subunit head and packaging 90.3 0.057 29-81 / 53-108
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 93.8 0.0068 31-83 / 16-73
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0044 19-81 / 29-99
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.7E-05 19-81 / 49-112
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 92.3 0.021 23-81 / 95-155

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05315.10 ICEA Protein 1.6E-06 138-193 / 80-150
PF05766.11 Bacteriophage Lambda NinG protein 2.9E-06 143-193 / 78-136
PF13395.5 HNH endonuclease 6.2E-06 154-193 / 1-51
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 1.7E-05 151-193 / 253-296
PF01844.22 HNH endonuclease 5.9E-05 154-192 / 1-47
PF14279.5 HNH endonuclease 7.5E-05 154-193 / 1-45
PF02945.14 Recombination endonuclease VII 0.0005 145-195 / 21-75
PF13391.5 HNH endonuclease 0.0011 154-193 / 1-45
PF06147.10 Protein of unknown function (DUF968) 0.0016 150-192 / 126-173

Annotations of the NCBI proteins of this PHROG


18:endonuclease VII 11:hypothetical protein 4:endonuclease 3:HNH endonuclease 2:recombination endonuclease VII 2:EndoVII 1:recombination endonuclease 1:endonuclease VII domain protein 1:endonuclease 7 1:13.5 kDa protein 1:endoVII 1:gp13.5

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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