phrog_2967 is made of 49 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
177.61 347 182


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p123578 no NCBI prot ID no annotation VI_00485 Bacilli_gi_500754380_342141_385119 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p156984 no NCBI prot ID no annotation VI_00815 Bacilli_gi_242362035_373302_413505 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p147254 no NCBI prot ID no annotation VI_00546 Bacilli_gi_501075363_2048191_2089324 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p161097 no NCBI prot ID no annotation VI_00817 Bacilli_gi_242355587_478649_518482 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p123375 no NCBI prot ID no annotation VI_00604 Bacilli_gi_502362932_34964_77961 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p145158 no NCBI prot ID no annotation VI_00601 Bacilli_gi_502327608_33351_74643 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p123762 no NCBI prot ID no annotation VI_00553 Bacilli_gi_501481354_33522_76500 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p161214 no NCBI prot ID no annotation VI_00579 Bacilli_gi_501941596_1706486_1746319 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p145823 no NCBI prot ID no annotation VI_00813 Bacilli_gi_242364291_479779_521001 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p123697 no NCBI prot ID no annotation VI_00487 Bacilli_gi_500897546_1522846_1565824 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_025453_p4 YP_009103040.1 XRE family transcriptional regulator NC_025453 Enterococcus phage EFC-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p285563 no NCBI prot ID no annotation VI_04526 Bacilli_gi_336232955 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p395191 no NCBI prot ID no annotation VI_04552 Bacilli_gi_430356286_17_14694 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p188915 no NCBI prot ID no annotation VI_00603 Bacilli_gi_502354864_246239_283567 Viruses.
p395175 no NCBI prot ID no annotation VI_04659 Bacilli_gi_430369546_17_14695 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p181046 no NCBI prot ID no annotation VI_00569 Bacilli_gi_501611608_959869_997959 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_013696_p36 YP_003358826.1 cI-like repressor NC_013696 Enterococcus phage phiEf11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p128374 no NCBI prot ID no annotation VI_00590 Bacilli_gi_502206344_994950_1037475 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p112143 no NCBI prot ID no annotation VI_00596 Bacilli_gi_502299557_1641431_1685718 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p142107 no NCBI prot ID no annotation VI_00858 Bacilli_gi_428765681_1849705_1891283 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p123823 no NCBI prot ID no annotation VI_00609 Bacilli_gi_502427206_1029360_1072336 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p128385 no NCBI prot ID no annotation VI_04470 Bacilli_gi_300860136_583915_626439 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p208022 no NCBI prot ID no annotation VI_00547 Bacilli_gi_501076900_1001297_1037319 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p128198 no NCBI prot ID no annotation VI_00607 Bacilli_gi_502424906_1033617_1076164 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p128614 no NCBI prot ID no annotation VI_00593 Bacilli_gi_502290128_1030126_1072642 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Enterococcus phage phiEf11.
p181102 no NCBI prot ID no annotation VI_00592 Bacilli_gi_502238181_1032628_1070718 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p97523 no NCBI prot ID no annotation VI_04032 Negativicutes_gi_485071342 Viruses.
MF959998_p33 ATN93271.1 hypothetical protein MF959998 Marinobacter phage PS6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_025428_p65 YP_009099722.1 HTH-domain containing protein NC_025428 Ruegeria phage DSS3-P1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MF476925_p7 ASW27626.1 putative HTH-domain containing protein MF476925 Klebsiella phage YMC16/01/N133_KPN_BP Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p48834 no NCBI prot ID no annotation VI_04311 Alphaproteobacteria_gi_557832156 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_018283_p70 YP_006561154.1 repressor NC_018283 Burkholderia phage AH2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ahduovirus; Burkholderia virus AH2.
p263842 no NCBI prot ID no annotation VI_00587 Bacilli_gi_502174949 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p396349 no NCBI prot ID no annotation VI_00942 Bacilli_gi_522837238 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p270467 no NCBI prot ID no annotation VI_00588 Bacilli_gi_502190608 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p262434 no NCBI prot ID no annotation VI_00809 Bacilli_gi_242364200 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p280143 no NCBI prot ID no annotation VI_00582 Bacilli_gi_501975299 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p331593 no NCBI prot ID no annotation VI_00558 Bacilli_gi_501569203 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p258638 no NCBI prot ID no annotation VI_00589 Bacilli_gi_502198097 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Enterococcus phage EF62phi.
p36908 no NCBI prot ID no annotation VI_00612 Bacilli_gi_505484066 Viruses.
p302057 no NCBI prot ID no annotation VI_00408 Bacilli_gi_423364702 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p32381 no NCBI prot ID no annotation VI_00731 Bacilli_gi_163937865 Viruses.
p201345 no NCBI prot ID no annotation VI_04413 Bacilli_gi_163806179 Viruses.
p401259 no NCBI prot ID no annotation VI_04549 Bacilli_gi_417695265 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p224417 no NCBI prot ID no annotation VI_04620 Bacilli_gi_418106402 Viruses.
NC_017972_p21 YP_006382551.1 putative transcriptional regulator NC_017972 Pseudomonas phage Lu11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p401769 no NCBI prot ID no annotation VI_05177 Bacilli_gi_511746626 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p85510 no NCBI prot ID no annotation VI_01346 Flavobacteriia_gi_423326479 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
p386868 no NCBI prot ID no annotation VI_01228 Clostridia_gi_547303947 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_87 993 metallo-protease other 28 7.29E-75 65.26
phrog_62 1174 DNA helicase DNA, RNA and nucleotide metabolism 5 3.79E-11 1.54
phrog_6201 20 CI-like repressor transcription regulation 2 1.33E-10 1.0

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1124 transcriptional regulator transcription regulation 95.4 0.00067 9-59 / 3-58
phrog_11423 no annotation unknown function 92.4 0.02 6-74 / 7-74
phrog_13326 no annotation unknown function 96.8 9.4E-06 8-76 / 2-71
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 96.0 0.00016 7-63 / 5-62
phrog_1373 transcriptional regulator transcription regulation 98.0 9.9E-09 9-68 / 32-90
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 97.5 2.9E-07 8-74 / 9-75
phrog_14076 transcriptional regulator transcription regulation 93.3 0.011 12-48 / 5-43
phrog_1468 transcriptional repressor transcription regulation 97.3 7E-07 5-67 / 4-64
phrog_147 transcriptional regulator transcription regulation 97.1 2.5E-06 8-75 / 2-70
phrog_1529 no annotation unknown function 92.4 0.02 10-49 / 5-42
phrog_1702 transcriptional repressor transcription regulation 94.2 0.0044 10-71 / 15-78
phrog_1728 transcriptional regulator transcription regulation 91.9 0.027 11-65 / 6-59
phrog_17822 no annotation unknown function 91.7 0.031 6-74 / 5-71
phrog_18104 transcriptional regulator transcription regulation 94.9 0.0016 24-63 / 16-54
phrog_18248 transcriptional regulator transcription regulation 91.8 0.028 11-75 / 5-66
phrog_18342 transcriptional repressor transcription regulation 95.5 0.00061 12-70 / 21-80
phrog_18815 no annotation unknown function 90.0 0.065 12-67 / 2-57
phrog_19114 no annotation unknown function 93.1 0.012 11-58 / 74-120
phrog_1994 DNA binding protein DNA, RNA and nucleotide metabolism 97.2 1.2E-06 11-112 / 2-90
phrog_2104 no annotation unknown function 97.1 2E-06 10-57 / 47-93
phrog_21705 no annotation unknown function 93.7 0.0076 9-70 / 120-180
phrog_2328 transcriptional repressor transcription regulation 98.6 4.7E-11 8-76 / 15-82
phrog_2339 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.1 0.00014 7-63 / 23-79
phrog_2439 transcriptional regulator transcription regulation 98.0 1.1E-08 7-72 / 5-69
phrog_27318 no annotation unknown function 94.5 0.003 7-75 / 3-69
phrog_296 DNA transposition protein integration and excision 95.8 0.00025 9-66 / 2-59
phrog_3037 transcriptional repressor transcription regulation 97.1 2.6E-06 6-76 / 14-81
phrog_32768 no annotation unknown function 94.7 0.0022 6-72 / 7-73
phrog_34197 no annotation unknown function 93.2 0.012 9-71 / 3-70
phrog_34341 transcriptional regulator transcription regulation 92.1 0.024 9-47 / 72-109
phrog_34939 no annotation unknown function 96.5 3.8E-05 9-76 / 10-76
phrog_3557 transcriptional regulator transcription regulation 96.6 2.3E-05 5-77 / 10-80
phrog_35 transcriptional repressor transcription regulation 95.2 0.001 22-69 / 14-62
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.6 0.00041 13-65 / 11-63
phrog_37093 transcriptional regulator transcription regulation 91.8 0.029 5-33 / 2-30
phrog_37751 no annotation unknown function 93.6 0.0084 10-52 / 138-181
phrog_38027 transcriptional repressor transcription regulation 94.0 0.0057 10-71 / 59-119
phrog_3949 transcriptional repressor transcription regulation 95.3 0.00082 7-70 / 14-75
phrog_3 transcriptional repressor transcription regulation 98.4 3.7E-10 8-71 / 3-65
phrog_4031 no annotation unknown function 94.6 0.0027 8-69 / 515-576
phrog_409 transcriptional regulator transcription regulation 94.9 0.0017 15-65 / 5-54
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 91.9 0.028 18-44 / 17-42
phrog_4268 transcriptional repressor transcription regulation 94.0 0.0055 5-64 / 32-88
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.6 0.00048 13-75 / 9-71
phrog_4583 transcriptional repressor transcription regulation 97.7 9.5E-08 5-72 / 7-73
phrog_4739 no annotation unknown function 96.0 0.00016 8-75 / 67-133
phrog_4779 transcriptional regulator transcription regulation 97.2 1.3E-06 9-66 / 2-60
phrog_4836 CII-like regulator transcription regulation 97.8 2.6E-08 7-76 / 81-149
phrog_4 transcriptional repressor transcription regulation 98.0 7.5E-09 8-76 / 3-66
phrog_5119 no annotation unknown function 90.0 0.064 9-49 / 54-93
phrog_517 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.9 0.045 13-47 / 72-104
phrog_5301 transcriptional repressor transcription regulation 92.4 0.021 18-72 / 20-79
phrog_5414 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.0 0.043 23-62 / 22-60
phrog_5736 transcriptional regulator transcription regulation 92.3 0.022 9-74 / 7-77
phrog_5823 transcriptional regulator transcription regulation 97.5 2.8E-07 6-76 / 2-72
phrog_6223 transcriptional repressor transcription regulation 94.0 0.0052 8-49 / 6-44
phrog_6288 no annotation unknown function 92.9 0.014 6-71 / 9-71
phrog_638 transcriptional regulator transcription regulation 96.3 6.1E-05 11-73 / 5-68
phrog_6463 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.8 0.002 12-75 / 24-94
phrog_6499 transcriptional regulator transcription regulation 95.7 0.00035 10-74 / 8-75
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 90.5 0.053 15-55 / 62-101
phrog_6831 transcriptional regulator transcription regulation 95.5 0.00054 15-59 / 9-54
phrog_6962 no annotation unknown function 91.9 0.027 11-52 / 4-44
phrog_7126 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.6 0.0083 7-75 / 13-83
phrog_7241 transcriptional regulator transcription regulation 97.8 3.2E-08 13-69 / 66-121
phrog_725 CII-like regulator transcription regulation 91.7 0.03 21-63 / 27-62
phrog_7396 no annotation unknown function 95.8 0.00032 5-76 / 9-81
phrog_769 transcriptional repressor transcription regulation 94.9 0.0018 11-72 / 15-72
phrog_7950 transcriptional repressor transcription regulation 94.3 0.0037 9-49 / 10-49
phrog_8038 no annotation unknown function 92.9 0.015 12-58 / 6-49
phrog_8898 no annotation unknown function 93.3 0.01 13-65 / 6-56
phrog_8 transcriptional regulator transcription regulation 98.9 9.8E-13 9-76 / 2-66
phrog_9103 transcriptional repressor transcription regulation 95.7 0.00034 14-74 / 12-72
phrog_925 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.1 0.005 8-66 / 4-61
phrog_955 HTH DNA binding protein DNA, RNA and nucleotide metabolism 92.6 0.018 4-64 / 32-94
phrog_9908 DNA binding protein DNA, RNA and nucleotide metabolism 93.6 0.0082 7-64 / 13-69

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 0.00012 110-170 / 8-76
PF13744.5 Helix-turn-helix domain 0.0005 112-170 / 18-79
PF05339.10 Protein of unknown function (DUF739) 0.0014 116-169 / 7-62
PF01381.21 Helix-turn-helix 0.0012 120-168 / 4-54
PF13413.5 Helix-turn-helix domain 0.0015 119-167 / 3-59
PF14590.5 Domain of unknown function (DUF4447) 0.0032 113-171 / 8-71
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.0015 119-172 / 5-60
PF04645.11 Protein of unknown function, DUF603 0.0056 112-160 / 7-60
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.002 119-171 / 4-61
PF12844.6 Helix-turn-helix domain 0.0019 119-171 / 6-60
PF13560.5 Helix-turn-helix domain 0.0052 115-168 / 4-62
PF05269.10 Bacteriophage CII protein 6.5E-05 32-95 / 8-71
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.0042 113-170 / 70-128
PF08667.9 BetR domain 0.00012 31-95 / 4-72
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.0042 122-172 / 6-57
PF08965.9 Domain of unknown function (DUF1870) 0.00022 34-86 / 3-57
PF14549.5 DNA-binding transcriptional regulator Cro 0.00064 38-91 / 3-52
PF13693.5 Winged helix-turn-helix DNA-binding 0.00078 35-93 / 5-60
PF00157.16 Pou domain - N-terminal to homeobox domain 0.0017 31-85 / 6-64
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0023 33-84 / 114-165
PF12116.7 Stage III sporulation protein D 0.0028 43-87 / 17-62
PF02376.14 CUT domain 0.006 31-93 / 6-67
PF00356.20 Bacterial regulatory proteins, lacI family 0.0065 47-80 / 1-34

Annotations of the NCBI proteins of this PHROG


2:HTH-domain containing protein 1:hypothetical protein 1:XRE family transcriptional regulator 1:repressor 1:cI-like repressor 1:transcriptional regulator

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K01356 lexA : repressor LexA [EC:3.4.21.88] no pathways 91 1

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0043565 sequence-specific DNA binding
GO:0003677 DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated

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