phrog_30580 is made of 2 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
85 85 85


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF001357_p65 ASZ76657.1 hypothetical protein MF001357 Clostridium phage CP3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
KY206887_p9 APQ41954.1 HNH endonuclease KY206887 Clostridium phage Clo-PEP-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3123 46 no annotation unknown function 2 5.00E-13 3.42

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
no PHROGs similar                                                                           

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00292.17 'Paired box' domain 6.3E-09 19-47 / 30-58
PF08822.10 Protein of unknown function (DUF1804) 3.3E-08 20-47 / 17-44
PF13011.5 leucine-zipper of insertion element IS481 1.8E-07 19-47 / 21-49
PF10654.8 Protein of unknown function (DUF2481) 1.7E-07 19-47 / 77-105
PF07141.10 Putative bacteriophage terminase small subunit 5.7E-07 18-47 / 27-56
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 1.2E-06 20-47 / 11-38
PF06322.10 Phage NinH protein 1.2E-06 20-47 / 14-41
PF09607.9 Brinker DNA-binding domain 2.1E-06 23-47 / 26-50
PF07750.10 GcrA cell cycle regulator 2.2E-06 18-47 / 14-44
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 2.3E-06 11-46 / 12-47
PF05344.10 Domain of Unknown Function (DUF746) 2.6E-06 20-47 / 10-37
PF04936.11 Protein of unknown function (DUF658) 0.00022 21-47 / 87-113
PF08535.9 KorB domain 3.4E-06 21-47 / 2-28
PF01710.15 Transposase 0.0099 21-46 / 69-94
PF01381.21 Helix-turn-helix 4.6E-06 19-46 / 6-33
PF12759.6 InsA C-terminal domain 5E-06 20-46 / 19-45
PF04552.12 Sigma-54, DNA binding domain 5.1E-06 19-47 / 45-73
PF10668.8 Phage terminase small subunit 5.6E-06 22-47 / 22-47
PF13413.5 Helix-turn-helix domain 5.8E-06 19-46 / 6-33
PF02954.18 Bacterial regulatory protein, Fis family 9.5E-06 20-45 / 14-39
PF06627.10 Protein of unknown function (DUF1153) 9.5E-06 20-47 / 44-71
PF17443.1 Uncharacterized protein pXO2-72 1E-05 21-46 / 7-32
PF00356.20 Bacterial regulatory proteins, lacI family 1.1E-05 24-46 / 1-23
PF08765.10 Mor transcription activator family 1.1E-05 21-47 / 71-97
PF13542.5 Helix-turn-helix domain of transposase family ISL3 1.4E-05 21-46 / 26-50
PF04218.12 CENP-B N-terminal DNA-binding domain 1.7E-05 22-47 / 23-48
PF13309.5 HTH domain 1.7E-05 23-44 / 42-63
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 1.8E-05 20-47 / 17-44
PF02796.14 Helix-turn-helix domain of resolvase 1.8E-05 20-45 / 19-44
PF03333.12 Adhesin biosynthesis transcription regulatory protein 2.1E-05 20-47 / 53-80
PF07453.12 NUMOD1 domain 2.1E-05 22-43 / 19-40
PF13411.5 MerR HTH family regulatory protein 2.2E-05 24-47 / 2-25
PF07278.10 Protein of unknown function (DUF1441) 2.2E-05 22-46 / 1-25
PF12116.7 Stage III sporulation protein D 2.3E-05 21-46 / 18-43
PF00376.22 MerR family regulatory protein 2.5E-05 25-46 / 2-23
PF13404.5 AsnC-type helix-turn-helix domain 2.7E-05 20-46 / 15-41
PF06806.11 Putative excisionase (DUF1233) 3.1E-05 22-44 / 9-31
PF02042.14 RWP-RK domain 3.4E-05 20-47 / 10-37
PF14493.5 Helix-turn-helix domain 3.4E-05 20-47 / 10-37
PF11112.7 Pyocin activator protein PrtN 3.4E-05 21-46 / 12-38
PF02319.19 E2F/DP family winged-helix DNA-binding domain 3.5E-05 21-47 / 22-48
PF14590.5 Domain of unknown function (DUF4447) 3.7E-05 19-46 / 17-44
PF04645.11 Protein of unknown function, DUF603 3.8E-05 16-46 / 14-47
PF15978.4 Tn7-like transposition protein D 3.9E-05 21-47 / 202-228
PF12824.6 Mitochondrial ribosomal protein subunit L20 3.8E-05 22-46 / 107-131
PF13412.5 Winged helix-turn-helix DNA-binding 4.3E-05 21-47 / 16-42
PF06970.10 Replication initiator protein A (RepA) N-terminus 4.8E-05 24-45 / 53-74
PF13022.5 Helix-turn-helix of insertion element transposase 5E-05 22-45 / 25-48
PF05225.15 helix-turn-helix, Psq domain 5.2E-05 20-47 / 14-42
PF07037.10 Putative transcription regulator (DUF1323) 5.3E-05 23-45 / 1-23
PF05339.10 Protein of unknown function (DUF739) 5.6E-05 20-45 / 14-39
PF13591.5 MerR HTH family regulatory protein 5.7E-05 24-45 / 2-23
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 5.9E-05 22-44 / 3-25
PF13936.5 Helix-turn-helix domain 6.9E-05 20-44 / 18-42
PF16677.4 DNA-packaging protein gp3 7.4E-05 21-46 / 28-53
PF16087.4 Domain of unknown function (DUF4817) 7.6E-05 18-47 / 12-49
PF01527.19 Transposase 7.9E-05 20-47 / 19-46
PF10743.8 Regulatory phage protein cox 7.9E-05 20-47 / 9-36
PF11427.7 Tc3 transposase 8.4E-05 20-47 / 18-45
PF07638.10 ECF sigma factor 8.7E-05 19-47 / 146-174
PF13551.5 Winged helix-turn helix 9.1E-05 21-47 / 10-36
PF13443.5 Cro/C1-type HTH DNA-binding domain 9.1E-05 20-45 / 8-34
PF09035.9 Excisionase from transposon Tn916 9.5E-05 20-44 / 13-37
PF07825.10 Excisionase-like protein 9.6E-05 23-47 / 3-29
PF13556.5 PucR C-terminal helix-turn-helix domain 0.00011 21-47 / 11-37
PF05331.10 Protein of unknown function (DUF742) 0.00011 21-47 / 52-78
PF13518.5 Helix-turn-helix domain 0.00012 21-47 / 10-36
PF07506.10 RepB plasmid partitioning protein 0.00012 19-46 / 18-45
PF01371.18 Trp repressor protein 0.00013 19-47 / 45-73
PF09012.9 FeoC like transcriptional regulator 0.00013 20-47 / 12-39
PF08222.10 CodY helix-turn-helix domain 0.00013 21-47 / 3-29
PF13744.5 Helix-turn-helix domain 0.00014 19-46 / 28-55
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00016 22-47 / 11-36
PF08281.11 Sigma-70, region 4 0.00017 20-46 / 24-50
PF07471.11 Phage DNA packaging protein Nu1 0.00017 23-45 / 3-25
PF05269.10 Bacteriophage CII protein 0.00017 19-45 / 20-46
PF08965.9 Domain of unknown function (DUF1870) 0.00018 19-46 / 11-40
PF12964.6 Protein of unknown function (DUF3853) 0.00019 21-46 / 44-69
PF14549.5 DNA-binding transcriptional regulator Cro 0.0002 20-42 / 8-29
PF12728.6 Helix-turn-helix domain 0.0002 23-45 / 2-25
PF16221.4 winged helix-turn-helix 0.00021 22-47 / 46-71
PF16509.4 TrfB plasmid transcriptional repressor 0.00022 20-47 / 29-56
PF05043.12 Mga helix-turn-helix domain 0.00021 20-47 / 28-55
PF02082.19 Transcriptional regulator 0.00022 23-47 / 25-49
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00023 19-47 / 15-43
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.00022 19-45 / 123-149
PF00325.19 Bacterial regulatory proteins, crp family 0.00024 23-47 / 3-27
PF11242.7 Protein of unknown function (DUF2774) 0.00023 19-47 / 11-39
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.00024 21-46 / 10-36
PF04492.12 Bacteriophage replication protein O 0.00028 22-47 / 49-74
PF06971.12 Putative DNA-binding protein N-terminus 0.00028 22-43 / 27-48
PF12844.6 Helix-turn-helix domain 0.00034 20-45 / 10-35
PF04545.15 Sigma-70, region 4 0.00038 21-46 / 23-48
PF04967.11 HTH DNA binding domain 0.00039 22-47 / 23-48
PF00440.22 Bacterial regulatory proteins, tetR family 0.00039 23-46 / 16-39
PF01022.19 Bacterial regulatory protein, arsR family 0.00052 21-47 / 15-41
PF09182.9 Bacterial purine repressor, N-terminal 0.00052 20-47 / 18-45
PF13384.5 Homeodomain-like domain 0.00055 21-46 / 16-41
PF08279.11 HTH domain 0.00057 21-47 / 14-40
PF10975.7 Protein of unknown function (DUF2802) 0.00059 15-44 / 36-65
PF00157.16 Pou domain - N-terminal to homeobox domain 0.00065 20-45 / 18-49
PF09904.8 Winged helix-turn helix 0.0007 20-47 / 19-46
PF01418.16 Helix-turn-helix domain, rpiR family 0.00075 22-47 / 34-59
PF13693.5 Winged helix-turn-helix DNA-binding 0.00077 20-45 / 13-38
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.00077 24-46 / 10-31
PF13560.5 Helix-turn-helix domain 0.00082 19-45 / 11-37
PF12802.6 MarR family 0.00098 23-47 / 22-46
PF09048.9 Cro 0.00097 21-47 / 12-38
PF07900.10 Protein of unknown function (DUF1670) 0.001 20-47 / 93-120
PF16264.4 SatD family (SatD) 0.0011 21-46 / 170-195
PF07618.10 Protein of unknown function (DUF1580) 0.0011 27-46 / 7-26
PF15977.4 Winged helix-turn-helix DNA binding 0.0012 22-47 / 23-48
PF06413.10 Neugrin 0.0012 22-45 / 29-52
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.0013 22-47 / 22-47
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.0013 20-47 / 31-58
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.0014 20-46 / 80-106
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.0014 21-47 / 19-45
PF00196.18 Bacterial regulatory proteins, luxR family 0.0014 20-47 / 15-42
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.0014 20-44 / 22-46
PF06530.11 Phage antitermination protein Q 0.0015 19-47 / 76-104
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.0016 20-47 / 25-52
PF13601.5 Winged helix DNA-binding domain 0.0017 20-47 / 12-39
PF09339.9 IclR helix-turn-helix domain 0.0017 23-47 / 19-43
PF05584.10 Sulfolobus plasmid regulatory protein 0.0017 20-47 / 16-43
PF01047.21 MarR family 0.0017 21-47 / 16-42
PF11972.7 HTH DNA binding domain 0.0018 20-46 / 11-37
PF02001.15 Protein of unknown function DUF134 0.0018 20-47 / 45-72
PF00392.20 Bacterial regulatory proteins, gntR family 0.0019 21-47 / 22-49
PF14947.5 Winged helix-turn-helix 0.0026 20-47 / 14-41
PF07374.10 Protein of unknown function (DUF1492) 0.0028 20-45 / 69-94
PF06163.10 Bacterial protein of unknown function (DUF977) 0.0034 20-47 / 24-51
PF13463.5 Winged helix DNA-binding domain 0.0036 21-47 / 16-42
PF08667.9 BetR domain 0.0036 19-46 / 15-46
PF05732.10 Firmicute plasmid replication protein (RepL) 0.004 21-47 / 74-100
PF04703.11 FaeA-like protein 0.0042 21-47 / 13-39
PF02002.16 TFIIE alpha subunit 0.0043 20-47 / 24-51
PF13171.5 Protein of unknown function (DUF4004) 0.004 23-46 / 3-26
PF04182.11 B-block binding subunit of TFIIIC 0.0049 21-47 / 17-43
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.005 21-47 / 20-46
PF09862.8 Protein of unknown function (DUF2089) 0.0052 21-47 / 48-74
PF02295.16 Adenosine deaminase z-alpha domain 0.0053 22-47 / 18-44
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0053 21-47 / 21-47
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0058 21-47 / 16-42
PF14502.5 Helix-turn-helix domain 0.006 22-47 / 6-31
PF06892.10 Phage regulatory protein CII (CP76) 0.0062 23-46 / 20-43
PF13545.5 Crp-like helix-turn-helix domain 0.007 21-47 / 26-52
PF06969.15 HemN C-terminal domain 0.0082 20-47 / 18-46
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.0096 21-47 / 15-43

Annotations of the NCBI proteins of this PHROG


1:HNH endonuclease 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006352 DNA-templated transcription, initiation
GO:0003723 RNA binding
GO:0051775 response to redox state
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0019069 viral capsid assembly
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0006276 plasmid maintenance
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity
GO:0009289 pilus
GO:0006260 DNA replication
GO:0005622 intracellular
GO:0045893 positive regulation of transcription, DNA-templated
GO:0007131 reciprocal meiotic recombination
GO:0016987 sigma factor activity
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0003677 DNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006310 DNA recombination

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