phrog_3066 is made of 47 protein sequences and is annotated as "toxin of TA system"
Functional category: moron, auxiliary metabolic gene and host takeover


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
96.34 143 96


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p12382 no NCBI prot ID no annotation VI_11444 Gammaproteobacteria_gi_550551625 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p34255 no NCBI prot ID no annotation VI_11901 Gammaproteobacteria_gi_565822667_478576_541923 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p414268 no NCBI prot ID no annotation VI_07141 Gammaproteobacteria_gi_417193850 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p55313 no NCBI prot ID no annotation VI_07981 Gammaproteobacteria_gi_419213154 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
MF356679_p70 ASR76360.1 RelE family mRNA endonuclease addiction module toxin MF356679 Escherichia phage D6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
p38419 no NCBI prot ID no annotation VI_11448 Gammaproteobacteria_gi_550551904 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p9561 no NCBI prot ID no annotation VI_02338 Gammaproteobacteria_gi_476381012 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p5858 no NCBI prot ID no annotation VI_01627 Gammaproteobacteria_gi_545247476 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p8877 no NCBI prot ID no annotation VI_01875 Gammaproteobacteria_gi_422752328 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p217835 no NCBI prot ID no annotation VI_07456 Gammaproteobacteria_gi_418044409 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p256473 no NCBI prot ID no annotation VI_06813 Gammaproteobacteria_gi_415819523 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p238334 no NCBI prot ID no annotation VI_06641 Gammaproteobacteria_gi_261492216 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p7366 no NCBI prot ID no annotation VI_02970 Gammaproteobacteria_gi_510944733 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p340443 no NCBI prot ID no annotation VI_08039 Gammaproteobacteria_gi_419250340 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p329154 no NCBI prot ID no annotation VI_04355 Alphaproteobacteria_gi_484042176 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p142964 no NCBI prot ID no annotation VI_03022 Gammaproteobacteria_gi_170729251_1206887_1248417 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p343862 no NCBI prot ID no annotation VI_11472 Gammaproteobacteria_gi_544952661 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
p108422 no NCBI prot ID no annotation VI_04298 Alphaproteobacteria_gi_523692486 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p79484 no NCBI prot ID no annotation VI_11488 Gammaproteobacteria_gi_545091524 Viruses.
p35533 no NCBI prot ID no annotation VI_01730 Gammaproteobacteria_gi_545278032_51107_114058 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
MG710528_p17 AVD99041.1 plasmid maintenance system killer MG710528 Escherichia phage GER2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; Sepvirinae; Oslovirus; unclassified Oslovirus.
NC_028853_p51 YP_009203417.1 plasmid maintenance system killer HigB NC_028853 Mannheimia phage vB_MhS_535AP2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KP137439_p55 AJA73419.1 plasmid maintenance system killer HigB KP137439 Mannheimia phage vB_MhS_3927AP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p209602 no NCBI prot ID no annotation VI_08256 Gammaproteobacteria_gi_452721307_45460_81388 Viruses.
p91624 no NCBI prot ID no annotation VI_05685 Betaproteobacteria_gi_487565741 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_028956_p52 YP_009213810.1 plasmid maintenance system killer HigB NC_028956 Mannheimia phage vB_MhS_1152AP2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p59807 no NCBI prot ID no annotation VI_05661 Betaproteobacteria_gi_487495181 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p79514 no NCBI prot ID no annotation VI_11488 Gammaproteobacteria_gi_545091524 Viruses.
p241364 no NCBI prot ID no annotation VI_05738 Betaproteobacteria_gi_348618597 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p330087 no NCBI prot ID no annotation VI_10197 Gammaproteobacteria_gi_544677206 Viruses.
p376385 no NCBI prot ID no annotation VI_05716 Betaproteobacteria_gi_545068473 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p120369 no NCBI prot ID no annotation VI_05662 Betaproteobacteria_gi_487498307 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p47188 no NCBI prot ID no annotation VI_12342 Spirochaetia_gi_469851180 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p26088 no NCBI prot ID no annotation VI_12353 Spirochaetia_gi_418727951 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p47757 no NCBI prot ID no annotation VI_12350 Spirochaetia_gi_469875161 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p333902 no NCBI prot ID no annotation VI_11798 Gammaproteobacteria_gi_565818428 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
p389732 no NCBI prot ID no annotation VI_05512 Betaproteobacteria_gi_149146715 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
p242638 no NCBI prot ID no annotation VI_04220 Alphaproteobacteria_gi_402850157 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p407552 no NCBI prot ID no annotation VI_03456 Gammaproteobacteria_gi_386056071_5282555_5295806 Viruses.
p212966 no NCBI prot ID no annotation VI_12436 Spirochaetia_gi_523647848 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p441261 no NCBI prot ID no annotation VI_09023 Gammaproteobacteria_gi_485053607_0_6682 Viruses.
p21654 no NCBI prot ID no annotation VI_12352 Spirochaetia_gi_418714845 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p391982 no NCBI prot ID no annotation VI_03458 Gammaproteobacteria_gi_386083114_1573852_1588909 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p391919 no NCBI prot ID no annotation VI_03024 Gammaproteobacteria_gi_182680572_453845_468903 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p391941 no NCBI prot ID no annotation VI_02991 Gammaproteobacteria_gi_28197945_453992_469050 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p8032 no NCBI prot ID no annotation VI_07028 Gammaproteobacteria_gi_416495320 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p73697 no NCBI prot ID no annotation VI_08937 Gammaproteobacteria_gi_395794507 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1381 108 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 48 1.78E-188 178.87
phrog_8947 12 no annotation unknown function 2 5.58E-11 1.37

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1213 RelE-like toxin moron, auxiliary metabolic gene and host takeover 97.1 2.9E-06 20-85 / 15-70

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF15738.4 Bacterial toxin of type II toxin-antitoxin system, YafQ 2.1E-10 23-117 / 1-87
PF15781.4 ParE-like toxin of type II bacterial toxin-antitoxin system 7.1E-10 25-117 / 1-82
PF05016.14 ParE toxin of type II toxin-antitoxin system, parDE 7.3E-10 25-117 / 1-88
PF06769.13 YoeB-like toxin of bacterial type II toxin-antitoxin system 4.1E-09 27-113 / 1-80
PF05015.12 RelE-like toxin of type II toxin-antitoxin system HigB 2.1E-07 43-104 / 20-82
PF05973.13 Phage derived protein Gp49-like (DUF891) 1.7E-05 83-115 / 36-71
PF11663.7 Toxin with endonuclease activity, of toxin-antitoxin system 3E-05 75-111 / 61-99

Annotations of the NCBI proteins of this PHROG


3:plasmid maintenance system killer HigB 1:plasmid maintenance system killer 1:RelE family mRNA endonuclease addiction module toxin

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K07334 higA : proteic killer suppression protein no pathways 204 47

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0110001 toxin-antitoxin complex
GO:0004519 endonuclease activity
GO:0004540 ribonuclease activity
GO:0006401 RNA catabolic process

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