phrog_3151 is made of 46 protein sequences and is annotated as "inhibitor of MrcBC restriction"
Functional category: moron, auxiliary metabolic gene and host takeover


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
91.57 97 92


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MG250484_p289 AUE23162.1 hypothetical protein MG250484 Citrobacter phage CF1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Moonvirus; Citrobacter virus CF1.
NC_028857_p288 YP_009204002.1 hypothetical protein NC_028857 Citrobacter phage Merlin Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Moonvirus.
NC_027331_p282 YP_009146715.1 hypothetical protein NC_027331 Citrobacter phage Moon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Moonvirus.
MG746602_p151 AUO78776.1 hypothetical protein MG746602 Klebsiella phage vB_Kpn_F48 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; unclassified Tevenvirinae.
NC_024125_p260 YP_009030865.1 inhibitor of MrcBC restriction endonuclease NC_024125 Escherichia phage vB_EcoM_112 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
KY290975_p248 APU02606.1 inhibitor of MrcBC restriction nuclease KY290975 Escherichia phage YUEEL01 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
MF327008_p104 AUV63281.1 inhibitor of restriction endonuclease MF327008 Shigella phage Sf24 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Shigella virus Sf24.
NC_028927_p88 YP_009210173.1 putative inhibitor of MrcBC restriction nuclease [Shigella phage Shfl2] NC_028927 Escherichia phage slur02 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_025448_p249 YP_009102454.1 inhibitor of MrcBC restriction nuclease NC_025448 Enterobacteria phage RB27 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
MF327009_p109 AUV63389.1 inhibitor of restriction endonuclease MF327009 Shigella phage Sf25 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_025419_p252 YP_009098638.1 inhibitor of MrcBC restriction nuclease NC_025419 Enterobacteria phage RB3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_019503_p246 YP_007004628.1 inhibitor of MrcBC restriction endonuclease NC_019503 Escherichia phage ime09 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
KM607003_p254 AIT75438.1 inhibitor of MrcBC restriction nuclease KM607003 Enterobacteria phage RB59 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia virus T4.
KX828711_p246 APC45030.1 inhibitor of MrcBC restriction endonuclease KX828711 Shigella phage SH7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
MG775043_p204 AUV59623.1 anti-restriction nuclease MG775043 Citrobacter phage vB_CroM_CrRp10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_019505_p252 YP_007004994.1 inhibitor of MrcBC restriction endonuclease NC_019505 Escherichia phage wV7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
KU255730_p7 ALY07812.1 inhibitor of MrcBC restriction nuclease KU255730 Escherichia phage phiE142 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Mosigvirus; unclassified Mosigvirus.
NC_027349_p242 YP_009148693.1 putative inhibitor of MrcBC restriction endonuclease NC_027349 Escherichia phage HY01 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_015457_p246 YP_004415145.1 putative inhibitor of MrcBC restriction nuclease NC_015457 Shigella phage Shfl2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_025449_p250 YP_009102726.1 hypothetical protein NC_025449 Escherichia phage ECML-134 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_031030_p248 YP_009281588.1 inhibitor of MrcBC restriction endonuclease NC_031030 Escherichia phage UFV-AREG1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_025829_p260 YP_009111068.1 hypothetical protein NC_025829 Shigella phage pSs-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
MG781190_p251 AUV61114.1 inhibitor of MrcBC restriction endonuclease MG781190 Escherichia phage vB_EcoM-fFiEco06 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_031011_p82 YP_009278980.1 anti-restriction nuclease NC_031011 Shigella phage SHFML-26 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_027404_p252 YP_009153855.1 inhibitor of MrcBC restriction endonuclease NC_027404 Yersinia phage PST Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
MF001354_p149 ASZ76166.1 anti-restriction nuclease MF001354 Salmonella phage SG1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
KU925172_p13 ANH49616.1 hypothetical protein KU925172 Escherichia phage PE37 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
MF327007_p246 AUV63799.1 inhibitor of restriction endonuclease MF327007 Shigella phage Sf21 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Shigella virus Sf21.
NC_008515_p248 YP_803190.1 inhibitor of MrcBC restriction nuclease NC_008515 Enterobacteria phage RB32 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_027979_p253 YP_009167622.1 inhibitor of MrcBC restriction nuclease NC_027979 Enterobacteria phage RB68 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
MF001360_p6 ASZ77109.1 anti-restriction nuclease MF001360 Escherichia phage ECO4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_030953_p157 YP_009277627.1 anti-restriction nuclease NC_030953 Shigella phage SHFML-11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_012638_p250 YP_002854586.1 inhibitor of MrcBC restriction nuclease NC_012638 Enterobacteria phage RB14 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_031103_p250 YP_009290516.1 hypothetical protein NC_031103 Escherichia phage vB_EcoM-UFV13 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_000866_p257 NP_049868.1 Arn inhibitor of MrcBC restriction endonuclease (anti-restriction nuclease) NC_000866 Enterobacteria phage T4 (T4) Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_019399_p260 YP_006986811.1 inhibitor of MrcBC restriction endonuclease NC_019399 Escherichia phage vB_EcoM_ACG-C40 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_012635_p253 YP_002854208.1 inhibitor of MrcBC restriction nuclease NC_012635 Enterobacteria phage RB51 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
MF001359_p247 ASZ77085.1 anti-restriction nuclease MF001359 Escherichia phage EC121 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_028780_p8 YP_009197204.1 hypothetical protein NC_028780 Escherichia phage slur07 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
NC_031047_p210 YP_009284205.1 putative baseplate wedge tail fiber connector NC_031047 Escherichia phage HY03 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia virus HY03.
NC_027983_p263 YP_009168074.1 anti-restriction endonuclease NC_027983 Escherichia phage AR1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
MF158046_p101 ATE86511.1 inhibitor of restriction endonuclease MF158046 Shigella phage Sf23 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; unclassified Tequatrovirus.
KR233165_p149 AKN44636.1 putative inhibitor of MrcBC restriction endonuclease KR233165 Escherichia phage PEC04 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia virus HY01.
MF158045_p152 ATI16844.1 inhibitor of restriction endonuclease MF158045 Shigella phage Sf22 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Shigella virus Sf22.
AP014715_p279 BAQ23230.1 hypothetical protein AP014715 Edwardsiella phage PEi26 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; unclassified Tevenvirinae.
NC_028683_p280 YP_009190438.1 hypothetical protein NC_028683 Edwardsiella phage PEi20 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; unclassified Tevenvirinae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3762 38 no annotation unknown function 37 2.96E-156 146.65
phrog_1359 109 no annotation unknown function 32 2.55E-107 97.72
phrog_1844 82 unknown function unknown function 7 3.09E-22 12.63
phrog_6212 20 unknown function unknown function 6 7.15E-24 14.27
phrog_15853 6 no annotation unknown function 2 2.07E-11 1.81

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_20757 no annotation unknown function 92.0 0.026 12-91 / 13-92
phrog_31709 no annotation unknown function 95.6 0.00043 8-85 / 2-79

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
no PFAM domain similar to this PHROG                                             

Annotations of the NCBI proteins of this PHROG


11:hypothetical protein 11:inhibitor of MrcBC restriction nuclease 10:inhibitor of MrcBC restriction endonuclease 6:anti-restriction nuclease 5:inhibitor of restriction endonuclease 1:baseplate wedge tail fiber connector 1:Arn inhibitor of MrcBC restriction endonuclease 1:anti-restriction endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
no GO term               

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