phrog_31596 is made of 2 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
63.5 64 64


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_025445_p16 YP_009101365.1 hypothetical protein NC_025445 Enterobacteria phage J8-65 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Bonnellvirus; Escherichia virus J8-65.
NC_015585_p20 YP_004539093.1 hypothetical protein NC_015585 Pantoea phage LIMEzero Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Autographiviridae; Waewaevirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_19629 4 no annotation unknown function 1 8.89E-11 1.17

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
no PHROGs similar                                                                           

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF07141.10 Putative bacteriophage terminase small subunit 1.2E-07 4-55 / 4-56
PF12824.6 Mitochondrial ribosomal protein subunit L20 7.8E-07 8-54 / 85-131
PF02319.19 E2F/DP family winged-helix DNA-binding domain 1.4E-06 31-60 / 24-53
PF09607.9 Brinker DNA-binding domain 1.5E-06 12-58 / 6-53
PF06413.10 Neugrin 1.5E-06 7-53 / 6-52
PF13412.5 Winged helix-turn-helix DNA-binding 1.7E-06 32-58 / 19-45
PF04218.12 CENP-B N-terminal DNA-binding domain 1.9E-06 32-55 / 25-48
PF08822.10 Protein of unknown function (DUF1804) 0.0023 32-58 / 82-108
PF12759.6 InsA C-terminal domain 1.9E-06 32-54 / 23-45
PF04492.12 Bacteriophage replication protein O 1.9E-06 31-59 / 50-78
PF00292.17 'Paired box' domain 0.0033 32-51 / 95-124
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 2.3E-06 32-59 / 24-51
PF13011.5 leucine-zipper of insertion element IS481 3E-06 13-58 / 9-52
PF16221.4 winged helix-turn-helix 3.3E-06 31-59 / 47-75
PF05331.10 Protein of unknown function (DUF742) 3.9E-06 12-59 / 39-82
PF11427.7 Tc3 transposase 4.3E-06 32-58 / 22-48
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 4.6E-06 32-58 / 15-41
PF02796.14 Helix-turn-helix domain of resolvase 5.4E-06 32-53 / 23-44
PF01710.15 Transposase 0.0012 32-57 / 72-97
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 6.3E-06 32-57 / 21-46
PF13309.5 HTH domain 6.1E-06 32-52 / 43-63
PF08222.10 CodY helix-turn-helix domain 7.1E-06 31-59 / 5-33
PF10668.8 Phage terminase small subunit 9E-06 32-57 / 24-49
PF08535.9 KorB domain 1E-05 31-58 / 4-31
PF04936.11 Protein of unknown function (DUF658) 0.0002 31-57 / 89-115
PF13404.5 AsnC-type helix-turn-helix domain 1.2E-05 32-54 / 19-41
PF03333.12 Adhesin biosynthesis transcription regulatory protein 1.1E-05 32-56 / 57-81
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 1.2E-05 31-60 / 28-57
PF06322.10 Phage NinH protein 1.2E-05 32-58 / 18-44
PF05584.10 Sulfolobus plasmid regulatory protein 1.2E-05 31-59 / 19-47
PF07453.12 NUMOD1 domain 1.2E-05 32-51 / 21-40
PF06970.10 Replication initiator protein A (RepA) N-terminus 1.2E-05 32-54 / 53-75
PF03965.15 Penicillinase repressor 1.3E-05 31-60 / 19-53
PF12793.6 Sugar transport-related sRNA regulator N-term 1.5E-05 31-59 / 19-47
PF07638.10 ECF sigma factor 1.7E-05 32-55 / 151-174
PF16677.4 DNA-packaging protein gp3 1.8E-05 31-54 / 30-53
PF12802.6 MarR family 1.9E-05 32-59 / 23-50
PF02954.18 Bacterial regulatory protein, Fis family 2E-05 32-53 / 18-39
PF09012.9 FeoC like transcriptional regulator 1.9E-05 31-59 / 15-43
PF00356.20 Bacterial regulatory proteins, lacI family 2E-05 33-54 / 2-23
PF06627.10 Protein of unknown function (DUF1153) 2E-05 32-58 / 48-74
PF17443.1 Uncharacterized protein pXO2-72 2E-05 31-50 / 9-28
PF01022.19 Bacterial regulatory protein, arsR family 2.4E-05 32-58 / 18-44
PF13936.5 Helix-turn-helix domain 2.6E-05 32-52 / 22-42
PF07381.10 Winged helix DNA-binding domain (DUF1495) 2.4E-05 31-52 / 25-46
PF05225.15 helix-turn-helix, Psq domain 2.5E-05 32-55 / 18-42
PF13463.5 Winged helix DNA-binding domain 2.7E-05 31-59 / 18-46
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 2.7E-05 31-60 / 17-48
PF10654.8 Protein of unknown function (DUF2481) 2.7E-05 31-54 / 81-104
PF01527.19 Transposase 3.1E-05 32-55 / 23-46
PF05344.10 Domain of Unknown Function (DUF746) 3.2E-05 32-57 / 14-39
PF04358.12 DsrC like protein 3.1E-05 11-60 / 36-91
PF01418.16 Helix-turn-helix domain, rpiR family 3.8E-05 31-59 / 35-63
PF09339.9 IclR helix-turn-helix domain 3.9E-05 31-59 / 19-47
PF08765.10 Mor transcription activator family 3.9E-05 32-57 / 74-99
PF16087.4 Domain of unknown function (DUF4817) 4.1E-05 32-58 / 18-52
PF13411.5 MerR HTH family regulatory protein 4.2E-05 32-56 / 2-26
PF01726.15 LexA DNA binding domain 4.2E-05 31-59 / 26-55
PF15977.4 Winged helix-turn-helix DNA binding 4.2E-05 31-59 / 24-52
PF01978.18 Sugar-specific transcriptional regulator TrmB 4.5E-05 31-59 / 23-51
PF01047.21 MarR family 4.6E-05 32-59 / 19-46
PF04552.12 Sigma-54, DNA binding domain 5.1E-05 31-55 / 49-73
PF14277.5 Domain of unknown function (DUF4364) 5.2E-05 31-60 / 16-49
PF13022.5 Helix-turn-helix of insertion element transposase 5.2E-05 31-53 / 26-48
PF08784.10 Replication protein A C terminal 5.1E-05 31-60 / 59-91
PF04182.11 B-block binding subunit of TFIIIC 5.5E-05 31-59 / 19-47
PF05043.12 Mga helix-turn-helix domain 5.4E-05 31-56 / 31-56
PF14557.5 Putative AphA-like transcriptional regulator 5.7E-05 31-60 / 26-63
PF13601.5 Winged helix DNA-binding domain 6.3E-05 31-59 / 15-43
PF00376.22 MerR family regulatory protein 6.3E-05 33-54 / 2-23
PF08279.11 HTH domain 6.3E-05 31-58 / 16-43
PF05732.10 Firmicute plasmid replication protein (RepL) 6.6E-05 31-60 / 76-105
PF00325.19 Bacterial regulatory proteins, crp family 7.3E-05 32-58 / 4-30
PF02295.16 Adenosine deaminase z-alpha domain 7.3E-05 31-59 / 19-48
PF02082.19 Transcriptional regulator 8.2E-05 31-59 / 25-53
PF06806.11 Putative excisionase (DUF1233) 8.3E-05 31-52 / 10-31
PF13518.5 Helix-turn-helix domain 8.8E-05 32-59 / 13-40
PF00392.20 Bacterial regulatory proteins, gntR family 8.9E-05 32-59 / 26-53
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 9.4E-05 32-52 / 5-25
PF07037.10 Putative transcription regulator (DUF1323) 9.4E-05 32-53 / 2-23
PF02042.14 RWP-RK domain 9.7E-05 32-58 / 14-40
PF05158.11 RNA polymerase Rpc34 subunit 9.5E-05 31-60 / 109-138
PF07900.10 Protein of unknown function (DUF1670) 0.0001 31-59 / 96-124
PF06163.10 Bacterial protein of unknown function (DUF977) 0.0001 31-59 / 27-55
PF14493.5 Helix-turn-helix domain 0.00011 32-58 / 14-40
PF07278.10 Protein of unknown function (DUF1441) 0.0001 31-54 / 2-25
PF14947.5 Winged helix-turn-helix 0.00011 31-59 / 17-45
PF04545.15 Sigma-70, region 4 0.00011 32-54 / 26-48
PF13591.5 MerR HTH family regulatory protein 0.00011 32-53 / 2-23
PF01381.21 Helix-turn-helix 0.00012 31-53 / 10-32
PF09904.8 Winged helix-turn helix 0.00012 31-58 / 22-49
PF10743.8 Regulatory phage protein cox 0.00012 31-55 / 12-36
PF01475.18 Ferric uptake regulator family 0.00013 31-59 / 23-56
PF03551.13 Transcriptional regulator PadR-like family 0.00015 31-59 / 15-45
PF03428.12 Replication protein C N-terminal domain 0.00015 31-59 / 71-100
PF13556.5 PucR C-terminal helix-turn-helix domain 0.00015 32-57 / 14-39
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.00016 32-57 / 13-38
PF15978.4 Tn7-like transposition protein D 0.00016 32-56 / 205-229
PF16509.4 TrfB plasmid transcriptional repressor 0.00017 32-55 / 33-56
PF13545.5 Crp-like helix-turn-helix domain 0.00017 31-59 / 28-56
PF09035.9 Excisionase from transposon Tn916 0.00018 31-52 / 16-37
PF04967.11 HTH DNA binding domain 0.00019 32-56 / 25-49
PF08281.11 Sigma-70, region 4 0.00019 32-54 / 28-50
PF00440.22 Bacterial regulatory proteins, tetR family 0.00019 31-54 / 16-39
PF13413.5 Helix-turn-helix domain 0.00019 31-54 / 10-33
PF09182.9 Bacterial purine repressor, N-terminal 0.0002 31-56 / 21-46
PF02002.16 TFIIE alpha subunit 0.0002 31-59 / 27-55
PF09202.10 Rio2, N-terminal 0.00021 31-59 / 25-53
PF12728.6 Helix-turn-helix domain 0.00021 32-53 / 3-25
PF10711.8 Hypothetical protein (DUF2513) 0.00024 32-60 / 20-52
PF11313.7 Protein of unknown function (DUF3116) 0.00025 32-60 / 22-57
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.00026 31-59 / 22-50
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.00027 32-54 / 28-50
PF14502.5 Helix-turn-helix domain 0.00028 32-59 / 8-35
PF07471.11 Phage DNA packaging protein Nu1 0.00028 31-53 / 3-25
PF06971.12 Putative DNA-binding protein N-terminus 0.00034 31-51 / 28-48
PF03297.14 S25 ribosomal protein 0.00034 31-59 / 57-85
PF11242.7 Protein of unknown function (DUF2774) 0.00037 32-57 / 16-41
PF04079.15 Segregation and condensation complex subunit ScpB 0.00038 11-60 / 80-124
PF16264.4 SatD family (SatD) 0.0004 32-55 / 173-196
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.00041 31-59 / 18-46
PF13384.5 Homeodomain-like domain 0.00043 32-54 / 19-41
PF12964.6 Protein of unknown function (DUF3853) 0.00044 31-54 / 46-69
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.0005 31-59 / 25-53
PF06530.11 Phage antitermination protein Q 0.0005 32-54 / 81-103
PF12116.7 Stage III sporulation protein D 0.00053 31-54 / 20-43
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 0.00056 31-59 / 26-55
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.00055 32-54 / 35-57
PF13551.5 Winged helix-turn helix 0.0006 32-58 / 13-39
PF04703.11 FaeA-like protein 0.00061 31-59 / 15-43
PF07374.10 Protein of unknown function (DUF1492) 0.00064 32-54 / 73-95
PF07848.11 PaaX-like protein 0.00065 31-59 / 21-52
PF09639.9 YjcQ protein 0.00064 31-59 / 17-47
PF06969.15 HemN C-terminal domain 0.0007 31-59 / 21-50
PF07506.10 RepB plasmid partitioning protein 0.00068 32-54 / 23-45
PF01638.16 HxlR-like helix-turn-helix 0.00072 31-59 / 20-49
PF02334.15 Replication terminator protein 0.00071 32-61 / 33-71
PF08220.11 DeoR-like helix-turn-helix domain 0.00076 31-59 / 15-43
PF02001.15 Protein of unknown function DUF134 0.00081 32-54 / 49-71
PF01371.18 Trp repressor protein 0.00084 32-56 / 50-74
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.001 31-56 / 21-46
PF11972.7 HTH DNA binding domain 0.0011 31-54 / 14-37
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0011 32-53 / 13-34
PF12298.7 Eukaryotic mitochondrial regulator protein 0.0011 9-52 / 14-55
PF00196.18 Bacterial regulatory proteins, luxR family 0.0013 32-57 / 19-44
PF14056.5 Domain of unknown function (DUF4250) 0.0013 32-56 / 21-45
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 0.0015 31-54 / 24-47
PF09048.9 Cro 0.0017 32-56 / 15-39
PF16864.4 Dimerisation domain 0.0018 31-59 / 33-61
PF13730.5 Helix-turn-helix domain 0.0023 41-58 / 33-50
PF12840.6 Helix-turn-helix domain 0.0024 31-60 / 24-50
PF09862.8 Protein of unknown function (DUF2089) 0.0025 32-55 / 51-74
PF09681.9 N-terminal phage replisome organiser (Phage_rep_org_N) 0.0025 32-59 / 55-82
PF07618.10 Protein of unknown function (DUF1580) 0.0024 35-54 / 7-26
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.0024 31-59 / 23-51
PF13744.5 Helix-turn-helix domain 0.0025 31-53 / 32-54
PF05339.10 Protein of unknown function (DUF739) 0.0029 32-53 / 18-39
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.0031 32-53 / 13-35
PF14549.5 DNA-binding transcriptional regulator Cro 0.0036 32-50 / 11-29
PF12844.6 Helix-turn-helix domain 0.0044 32-53 / 14-35
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.0049 32-51 / 10-29
PF11994.7 Protein of unknown function (DUF3489) 0.0048 31-58 / 22-49
PF05269.10 Bacteriophage CII protein 0.0073 32-53 / 25-46
PF09397.9 Ftsk gamma domain 0.0083 31-59 / 20-48
PF14590.5 Domain of unknown function (DUF4447) 0.0092 31-53 / 21-43
PF13693.5 Winged helix-turn-helix DNA-binding 0.0095 32-53 / 17-38

Annotations of the NCBI proteins of this PHROG


1:protein of an unannotated phage 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0045892 negative regulation of transcription, DNA-templated
GO:0016987 sigma factor activity
GO:0007131 reciprocal meiotic recombination
GO:0004674 protein serine/threonine kinase activity
GO:0006383 transcription by RNA polymerase III
GO:0005622 intracellular
GO:0006468 protein phosphorylation
GO:0006274 DNA replication termination
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0003700 DNA binding transcription factor activity
GO:0006281 DNA repair
GO:0051775 response to redox state
GO:0003723 RNA binding
GO:0006352 DNA-templated transcription, initiation
GO:0006508 proteolysis
GO:0005666 DNA-directed RNA polymerase III complex
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0005667 transcription factor complex
GO:0009378 four-way junction helicase activity
GO:0009289 pilus
GO:0006260 DNA replication
GO:0006310 DNA recombination
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0003677 DNA binding
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0019069 viral capsid assembly
GO:0004252 serine-type endopeptidase activity
GO:0051304 chromosome separation
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0004803 transposase activity
GO:0043565 sequence-specific DNA binding

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