phrog_31645 is made of 2 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
1075 1075 1075


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MF547662_p24 AUO78242.1 type II restriction enzyme, methylase subunit MF547662 Clostridioides phage LIBA6276 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF547663_p24 AUO78414.1 type II restriction enzyme, methylase subunit MF547663 Clostridioides phage LIBA2945 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_13585 7 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_14586 no annotation unknown function 90.3 0.058 596-669 / 4-66
phrog_1600 DNA methyltransferase other 93.6 0.0085 473-705 / 49-234
phrog_16674 DNA methyltransferase other 96.2 0.00011 588-711 / 678-805
phrog_25988 no annotation unknown function 99.1 3E-14 104-744 / 118-998
phrog_2713 no annotation unknown function 98.2 2.1E-09 354-710 / 170-406
phrog_34860 no annotation unknown function 95.3 0.00079 473-692 / 202-385
phrog_3689 DNA methyltransferase other 92.5 0.018 596-680 / 2-77
phrog_6380 DNA methyltransferase other 97.1 2.5E-06 476-709 / 35-216
phrog_9133 no annotation unknown function 95.5 0.00057 466-707 / 98-252

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF02384.15 N-6 DNA Methylase 6.3E-16 356-723 / 2-253
PF13588.5 Type I restriction enzyme R protein N terminus (HSDR_N) 9.1E-10 49-167 / 1-99
PF01170.17 Putative RNA methylase family UPF0020 1.9E-08 474-548 / 28-113
PF13651.5 Adenine-specific methyltransferase EcoRI 2.7E-08 389-410 / 6-27
PF11599.7 RRNA methyltransferase AviRa 1.8E-07 473-547 / 48-96
PF07669.10 Eco57I restriction-modification methylase 1.9E-07 595-708 / 4-118
PF05971.11 Protein of unknown function (DUF890) 1.2E-06 474-547 / 103-148
PF10672.8 S-adenosylmethionine-dependent methyltransferase 1.3E-06 474-662 / 123-243
PF05175.13 Methyltransferase small domain 2.6E-06 474-660 / 31-141
PF01739.17 CheR methyltransferase, SAM binding domain 3.9E-06 474-546 / 33-84
PF04378.12 Ribosomal RNA large subunit methyltransferase D, RlmJ 4E-06 473-660 / 59-170
PF01564.16 Spermine/spermidine synthase domain 5.7E-06 474-677 / 18-152
PF01795.18 MraW methylase family 6.7E-06 472-546 / 18-65
PF05958.10 tRNA (Uracil-5-)-methyltransferase 9.8E-06 475-548 / 201-244
PF05401.10 Nodulation protein S (NodS) 1.5E-05 474-660 / 43-149
PF05185.15 PRMT5 arginine-N-methyltransferase 1.6E-05 474-546 / 59-108
PF05724.10 Thiopurine S-methyltransferase (TPMT) 1.7E-05 473-545 / 37-79
PF08003.10 Protein of unknown function (DUF1698) 1.8E-05 473-659 / 115-222
PF01189.16 16S rRNA methyltransferase RsmB/F 1.9E-05 474-546 / 8-53
PF13489.5 Methyltransferase domain 1.9E-05 473-546 / 20-64
PF01420.18 Type I restriction modification DNA specificity domain 2.2E-05 899-956 / 113-171
PF03848.13 Tellurite resistance protein TehB 2.2E-05 474-546 / 30-72
PF01861.15 Protein of unknown function DUF43 2.2E-05 474-660 / 43-150
PF06325.12 Ribosomal protein L11 methyltransferase (PrmA) 2.3E-05 474-547 / 172-216
PF03602.14 Conserved hypothetical protein 95 2.5E-05 473-660 / 36-144
PF07942.11 N2227-like protein 2.5E-05 473-546 / 56-99
PF02390.16 Putative methyltransferase 2.5E-05 475-546 / 2-45
PF05891.11 AdoMet dependent proline di-methyltransferase 3E-05 472-545 / 53-97
PF09445.9 RNA cap guanine-N2 methyltransferase 3.3E-05 476-546 / 2-42
PF02475.15 Met-10+ like-protein 3.5E-05 474-547 / 100-145
PF02527.14 rRNA small subunit methyltransferase G 3.9E-05 477-546 / 54-95
PF08123.12 Histone methylation protein DOT1 3.9E-05 472-546 / 40-86
PF01234.16 NNMT/PNMT/TEMT family 4.5E-05 473-546 / 55-99
PF13679.5 Methyltransferase domain 4.7E-05 474-546 / 25-75
PF12847.6 Methyltransferase domain 4.9E-05 474-546 / 14-58
PF10294.8 Lysine methyltransferase 5.3E-05 474-546 / 45-88
PF12147.7 Putative methyltransferase 6E-05 473-546 / 130-177
PF01269.16 Fibrillarin 7.3E-05 473-546 / 71-117
PF03291.15 mRNA capping enzyme 8.2E-05 474-546 / 59-102
PF11968.7 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 8.3E-05 595-660 / 106-155
PF06080.11 Protein of unknown function (DUF938) 8.3E-05 474-546 / 27-71
PF12692.6 S-adenosyl-L-methionine methyltransferase 0.0001 474-543 / 28-69
PF13847.5 Methyltransferase domain 0.00011 474-546 / 3-48
PF01209.17 ubiE/COQ5 methyltransferase family 0.00011 477-660 / 59-175
PF02005.15 N2,N2-dimethylguanosine tRNA methyltransferase 0.00014 474-547 / 100-146
PF00398.19 Ribosomal RNA adenine dimethylase 0.00014 473-546 / 29-72
PF07091.10 Ribosomal RNA methyltransferase (FmrO) 0.00014 474-546 / 102-146
PF02353.19 Mycolic acid cyclopropane synthetase 0.00015 473-545 / 60-103
PF04816.11 tRNA (adenine(22)-N(1))-methyltransferase 0.00017 478-546 / 1-41
PF09243.9 Mitochondrial small ribosomal subunit Rsm22 0.00018 473-546 / 33-79
PF00891.17 O-methyltransferase 0.00019 473-495 / 74-96
PF08704.9 tRNA methyltransferase complex GCD14 subunit 0.00021 471-547 / 37-86
PF05219.11 DREV methyltransferase 0.00022 474-544 / 90-130
PF03141.15 Putative S-adenosyl-L-methionine-dependent methyltransferase 0.00058 474-495 / 354-375
PF10017.8 Histidine-specific methyltransferase, SAM-dependent 0.00029 474-546 / 62-106
PF01135.18 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 0.0003 474-546 / 71-116
PF03269.13 Caenorhabditis protein of unknown function, DUF268 0.0003 476-543 / 2-40
PF03059.15 Nicotianamine synthase protein 0.00031 474-546 / 121-167
PF01728.18 FtsJ-like methyltransferase 0.00038 474-495 / 21-42
PF04672.11 S-adenosyl methyltransferase 0.00044 474-545 / 69-115
PF03492.14 SAM dependent carboxyl methyltransferase 0.00047 474-545 / 13-71
PF02636.16 Putative S-adenosyl-L-methionine-dependent methyltransferase 0.00049 474-546 / 17-68
PF08242.11 Methyltransferase domain 0.0005 479-546 / 1-42
PF04445.12 Putative SAM-dependent methyltransferase 0.00078 473-547 / 63-107
PF03686.12 Uncharacterised protein family (UPF0146) 0.00086 474-495 / 14-36
PF01596.16 O-methyltransferase 0.00088 474-546 / 48-93
PF06460.11 Coronavirus NSP13 0.00088 638-660 / 151-173
PF04989.11 Cephalosporin hydroxylase 0.0011 474-495 / 32-53
PF08241.11 Methyltransferase domain 0.0014 479-545 / 1-37
PF07757.12 Predicted AdoMet-dependent methyltransferase 0.0015 474-546 / 59-101
PF07021.11 Methionine biosynthesis protein MetW 0.0016 474-544 / 13-53
PF08468.10 Methyltransferase small domain N-terminal 0.0021 595-660 / 67-107
PF11312.7 Putative SAM-dependent methyltransferase 0.0026 474-546 / 143-196
PF05148.14 Hypothetical methyltransferase 0.0042 474-489 / 72-87
PF05711.10 Macrocin-O-methyltransferase (TylF) 0.0046 474-496 / 100-122
PF06962.11 Putative rRNA methylase 0.0047 595-659 / 47-98
PF14314.5 Virus-capping methyltransferase 0.0061 475-496 / 337-358
PF13649.5 Methyltransferase domain 0.0068 478-546 / 1-41
PF07279.10 Protein of unknown function (DUF1442) 0.0085 474-546 / 41-92

Annotations of the NCBI proteins of this PHROG


2:type II restriction enzyme, methylase subunit

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0008170 N-methyltransferase activity
GO:0031167 rRNA methylation
GO:0016429 tRNA (adenine-N1-)-methyltransferase activity
GO:0005737 cytoplasm
GO:0008168 methyltransferase activity
GO:0006412 translation
GO:0006396 RNA processing
GO:0006306 DNA methylation
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0009452 7-methylguanosine RNA capping
GO:0018024 histone-lysine N-methyltransferase activity
GO:0032259 methylation
GO:0009877 nodulation
GO:0030488 tRNA methylation
GO:0003677 DNA binding
GO:0001510 RNA methylation
GO:0006480 N-terminal protein amino acid methylation
GO:0008152 metabolic process
GO:0030418 nicotianamine biosynthetic process
GO:0008171 O-methyltransferase activity
GO:0003723 RNA binding
GO:0003824 catalytic activity
GO:0008033 tRNA processing
GO:0008990 rRNA (guanine-N2-)-methyltransferase activity
GO:0030410 nicotianamine synthase activity
GO:0006364 rRNA processing
GO:0005730 nucleolus
GO:0004809 tRNA (guanine-N2-)-methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0031515 tRNA (m1A) methyltransferase complex
GO:0008610 lipid biosynthetic process
GO:0008649 rRNA methyltransferase activity
GO:0070475 rRNA base methylation
GO:0009312 oligosaccharide biosynthetic process
GO:0006304 DNA modification

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