phrog_3228 is made of 45 protein sequences and is annotated as "replicative helicase-primase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
743.4 884 734


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_023608_p43 YP_009009967.1 putative phage replicative helicase-primase NC_023608 Salmonella phage vB_SenS-Ent2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; unclassified Jerseyvirus.
NC_026017_p46 YP_009113193.1 hypothetical protein NC_026017 Salmonella phage LSPA1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus.
JX202565_p25 AFO12361.1 putative replicative helicase-primase JX202565 Salmonella phage wksl3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; Salmonella virus wksl3.
NC_006940_p34 YP_224056.1 hypothetical protein NC_006940 Salmonella phage SS3e Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus.
MF001366_p3 ASZ78199.1 hypothetical protein MF001366 Salmonella phage ST1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; unclassified Jerseyvirus.
MF431252_p17 AST15463.1 primase/helicase MF431252 Salmonella phage vB_SenS_PVP-SE2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; unclassified Jerseyvirus.
KY379853_p6 APU02975.1 hypothetical protein KY379853 Salmonella phage LPSE1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; unclassified Jerseyvirus.
NC_022754_p45 YP_008767216.1 putative primase/helicase protein NC_022754 Salmonella phage SETP7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus.
NC_016763_p13 YP_005098109.1 hypothetical protein NC_016763 Salmonella phage SE2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus.
NC_021777_p51 YP_008239760.1 hypothetical protein NC_021777 Salmonella phage Jersey Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus.
NC_031021_p24 YP_009280152.1 DNA primase NC_031021 Salmonella phage MA12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; unclassified Jerseyvirus.
NC_027994_p42 YP_009168874.1 putative helicase-primase NC_027994 Escherichia phage K1-dep(1) Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus.
NC_027993_p44 YP_009168824.1 putative helicase-primase NC_027993 Escherichia phage K1-dep(4) Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus.
NC_031925_p33 YP_009322840.1 replicative helicase primase NC_031925 Salmonella phage BPS11Q3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; unclassified Jerseyvirus.
GU196280_p38 ADA82433.1 putative helicase-primase GU196280 Escherichia phage K1-ind(2) Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus; Escherichia virus K1ind2.
KY295898_p51 AQN31989.1 putative helicase-primase KY295898 Escherichia phage P AB-2017 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus; unclassified Kagunavirus.
NC_019539_p43 YP_007010496.1 putative phage replicative helicase primase NC_019539 Salmonella phage Ent1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus.
NC_028698_p1 YP_009191554.1 putative primase-helicase NC_028698 Salmonella phage f18SE Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus.
GU196279_p39 ADA82383.1 putative helicase-primase GU196279 Escherichia phage K1ind1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus; Escherichia virus K1ind1.
JX297445_p45 AFO12445.1 putative helicase-primase JX297445 Salmonella phage vB_SenS_AG11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; Salmonella virus AG11.
GU196281_p39 ADA82482.1 putative helicase-primase GU196281 Escherichia phage K1-ind(3) Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus; unclassified Kagunavirus.
KT962832_p33 ALN97472.1 putative primase-helicase KT962832 Salmonella phage fSE1C Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; Salmonella virus f18SE; Salmonella phage f18SE.
NC_022752_p47 YP_008767046.1 putative helicase/primase protein NC_022752 Salmonella phage SETP13 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus.
NC_024204_p43 YP_009035180.1 putative phage replicative helicase-primase NC_024204 Salmonella phage vB_SenS-Ent3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; unclassified Jerseyvirus.
MF153391_p26 ASH99356.1 putative helicase-primase MF153391 Escherichia phage ST2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus; unclassified Kagunavirus.
KY176369_p54 APM00310.1 replicative helicase-primase KY176369 Salmonella phage STP03 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus; unclassified Jerseyvirus.
NC_009232_p44 YP_001110815.1 putative primase/helicase protein NC_009232 Salmonella phage SETP3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Jerseyvirus.
NC_031081_p57 YP_009288179.1 DNA primase/helicase NC_031081 Escherichia phage Envy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus; unclassified Dhillonvirus.
NC_024783_p50 YP_009055328.1 putative helicase-primase NC_024783 Escherichia phage EK99P-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus.
MG099933_p50 ATS93274.1 putative replicative helicase/primease MG099933 Escherichia phage VB_EcoS-Golestan Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus; Escherichia virus Golestan.
NC_021775_p16 YP_008239613.1 putative phage replicative helicase/primease NC_021775 Salmonella phage FSL SP-031 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Cornellvirus.
NC_019724_p46 YP_007112653.1 hypothetical protein NC_019724 Escherichia phage HK578 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus.
NC_028901_p45 YP_009208131.1 hypothetical protein NC_028901 Escherichia phage slur05 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus; unclassified Dhillonvirus.
KX534341_p47 ANY30052.1 DNA primase/helicase KX534341 Escherichia phage Pride Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus; unclassified Dhillonvirus.
MF158037_p13 ATE85598.1 putative DNA primase/helicase MF158037 Salmonella phage St162 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Cornellvirus; unclassified Cornellvirus.
NC_031113_p22 YP_009291439.1 DNA primase/helicase NC_031113 Escherichia phage Gluttony Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus; unclassified Dhillonvirus.
NC_012223_p53 YP_008550166.1 putative replicative helicase/primease NC_012223 Escherichia virus SSL2009a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus.
NC_028695_p62 YP_009191407.1 putative replicative helicase/primease NC_028695 Enterobacter phage phiEap-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Cornellvirus; unclassified Cornellvirus.
NC_016566_p46 YP_004957482.1 putative helicase-primase NC_016566 Shigella phage EP23 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus.
NC_019419_p16 YP_006990402.1 putative helicase-primase NC_019419 Escherichia virus JL1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus.
NC_023555_p30 YP_009004677.1 putative replicative helicase/primase NC_023555 Edwardsiella phage eiAU-183 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Eiauvirus; unclassified Eiauvirus.
KY295896_p52 AQN31877.1 putative replicative helicase/primease KY295896 Escherichia phage L AB-2017 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus; unclassified Kagunavirus.
NC_013600_p48 YP_003344983.1 gp48 NC_013600 Sodalis phage SO1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus.
NC_027383_p54 YP_009152295.1 putative helicase-primase NC_027383 Escherichia phage YD-2008.s Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Dhillonvirus.
KY295895_p52 AQN31809.1 putative replicative helicase/primease KY295895 Escherichia phage G AB-2017 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Guernseyvirinae; Kagunavirus; unclassified Kagunavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_5169 25 no annotation unknown function 25 0 1000
phrog_9366 11 transposase integration and excision 11 0 1000
phrog_9839 11 no annotation unknown function 4 9.06E-19 9.16
phrog_23498 3 no annotation unknown function 3 0 1000
phrog_3127 46 no annotation unknown function 3 4.56E-12 2.46
phrog_23061 3 no annotation unknown function 3 0 1000
phrog_36357 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10537 no annotation unknown function 93.5 0.0087 127-253 / 389-543
phrog_13004 no annotation unknown function 94.3 0.0042 343-548 / 70-290
phrog_19 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 97.7 9.7E-08 344-563 / 185-420
phrog_2135 DNA primase DNA, RNA and nucleotide metabolism 92.3 0.022 76-230 / 507-651
phrog_239 DNA primase/helicase DNA, RNA and nucleotide metabolism 98.3 4.6E-10 339-548 / 293-531
phrog_243 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 96.3 6.8E-05 359-563 / 39-265
phrog_25693 no annotation unknown function 96.3 7.1E-05 342-602 / 37-305
phrog_256 DNA helicase DNA, RNA and nucleotide metabolism 99.2 3.5E-15 2-200 / 13-205
phrog_2597 DNA primase DNA, RNA and nucleotide metabolism 97.1 1.8E-06 340-526 / 354-544
phrog_2850 no annotation unknown function 99.7 6.6E-22 340-564 / 147-373
phrog_30286 no annotation unknown function 94.4 0.0035 347-532 / 95-289
phrog_3123 no annotation unknown function 99.0 1.5E-13 50-560 / 56-544
phrog_34715 no annotation unknown function 95.9 0.00024 83-196 / 4-131
phrog_6012 DNA helicase DNA, RNA and nucleotide metabolism 95.9 0.0002 326-546 / 112-335
phrog_6357 no annotation unknown function 94.3 0.0038 345-532 / 21-191
phrog_8337 DNA repair protein DNA, RNA and nucleotide metabolism 93.9 0.0061 340-475 / 46-170
phrog_906 DNA polymerase/primase DNA, RNA and nucleotide metabolism 99.6 2.2E-20 343-549 / 558-773
phrog_9765 DNA primase DNA, RNA and nucleotide metabolism 99.3 7E-16 4-205 / 12-207
phrog_97 UvsX-like recombinase other 96.1 0.00012 350-534 / 51-237

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF08800.9 VirE N-terminal domain 7.3E-13 62-187 / 2-119
PF00154.20 recA bacterial DNA recombination protein 5.6E-12 361-589 / 35-256
PF06745.12 KaiC 5.9E-12 363-597 / 5-229
PF03796.14 DnaB-like helicase C terminal domain 7.9E-12 363-580 / 6-240
PF08423.10 Rad51 5.5E-11 362-594 / 22-253
PF09807.8 Elongation complex protein 6 6.5E-11 363-578 / 1-242
PF07088.10 GvpD gas vesicle protein 2.6E-06 362-422 / 243-297
PF05625.10 PAXNEB protein 4.8E-09 478-562 / 196-276
PF16793.4 RepB DNA-primase from phage plasmid 2.8E-07 64-205 / 48-170
PF13481.5 AAA domain 5.5E-07 362-534 / 14-185
PF03846.13 Cell division inhibitor SulA 4.2E-06 364-426 / 10-65
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 5E-05 365-401 / 4-38
PF13479.5 AAA domain 9E-05 377-397 / 2-22
PF05621.10 Bacterial TniB protein 0.00013 378-401 / 39-62
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.00018 380-399 / 1-20
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.00023 379-402 / 2-25
PF05707.11 Zonular occludens toxin (Zot) 0.00063 379-398 / 2-21
PF07693.13 KAP family P-loop domain 0.00076 376-402 / 30-56
PF01637.17 ATPase domain predominantly from Archaea 0.0011 377-402 / 20-45
PF04665.11 Poxvirus A32 protein 0.0012 374-402 / 10-38
PF03266.14 NTPase 0.0014 380-402 / 2-24
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0056 680-728 / 11-57

Annotations of the NCBI proteins of this PHROG


12:helicase-primase 7:hypothetical protein 5:replicative helicase/primease 4:DNA primase/helicase 2:primase/helicase protein 2:phage replicative helicase-primase 2:phage replicative helicase/primease 2:replicative helicase-primase 2:primase-helicase 1:protein of an unannotated phage 1:DNA primase 1:phage replicative helicase primase 1:replicative helicase/primase 1:helicase/primase protein 1:primase/helicase 1:replicative helicase primase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K06919 K06919 : putative DNA primase/helicase no pathways 86 25

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006281 DNA repair
GO:0000166 nucleotide binding
GO:0003697 single-stranded DNA binding
GO:0006355 regulation of transcription, DNA-templated
GO:0002098 tRNA wobble uridine modification
GO:0051188 cofactor biosynthetic process
GO:0051782 negative regulation of cell division
GO:0033588 Elongator holoenzyme complex
GO:0009236 cobalamin biosynthetic process
GO:0005524 ATP binding
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0005667 transcription factor complex
GO:0003678 DNA helicase activity
GO:0006260 DNA replication
GO:0009432 SOS response
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0003700 DNA binding transcription factor activity

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