phrog_32453 is made of 2 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
175 175 175


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_031254_p78 YP_009303361.1 HNH endonuclease NC_031254 Arthrobacter phage Kitkat Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Kelleziovirus.
NC_031231_p76 YP_009301333.1 HNH endonuclease NC_031231 Arthrobacter phage KellEzio Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Kelleziovirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_36977 2 no annotation unknown function 2 0 1000
phrog_28555 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 93.2 0.012 66-119 / 95-155
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 93.2 0.012 64-119 / 23-84
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 95.8 0.00028 69-119 / 143-202
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.8E-06 60-121 / 47-117
phrog_15103 no annotation unknown function 94.3 0.0041 70-114 / 198-251
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 92.8 0.015 60-114 / 68-127
phrog_16986 no annotation unknown function 90.0 0.064 72-117 / 20-68
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 90.3 0.057 69-126 / 13-83
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.7E-06 62-129 / 25-91
phrog_22514 HNH endonuclease DNA, RNA and nucleotide metabolism 90.4 0.055 65-113 / 59-107
phrog_2255 HNH endonuclease DNA, RNA and nucleotide metabolism 95.8 0.00032 63-122 / 58-132
phrog_25184 HNH endonuclease DNA, RNA and nucleotide metabolism 92.8 0.015 84-132 / 127-173
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 91.3 0.037 74-136 / 12-97
phrog_3106 HNH endonuclease DNA, RNA and nucleotide metabolism 94.0 0.0056 72-121 / 44-110
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 96.7 1.8E-05 81-120 / 40-76
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 95.6 0.00047 70-120 / 26-86
phrog_3497 no annotation unknown function 91.6 0.032 70-113 / 24-96
phrog_4234 HNH endonuclease DNA, RNA and nucleotide metabolism 91.4 0.035 69-120 / 24-86
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 97.2 1.8E-06 63-119 / 14-73
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 97.7 6E-08 60-119 / 35-101
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 92.0 0.026 81-126 / 19-66
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 8.5E-07 72-119 / 5-56
phrog_7275 no annotation unknown function 93.0 0.013 85-120 / 8-43
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2E-05 72-113 / 41-82
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 95.4 0.00073 72-147 / 18-105
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 97.0 3.7E-06 71-123 / 67-117
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 92.4 0.021 64-117 / 19-79
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 93.1 0.013 67-118 / 105-156

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF05315.10 ICEA Protein 2.3E-08 59-116 / 80-149
PF13395.5 HNH endonuclease 4E-08 75-117 / 1-51
PF01844.22 HNH endonuclease 8.8E-08 75-116 / 1-47
PF05766.11 Bacteriophage Lambda NinG protein 1.7E-07 59-118 / 73-137
PF14279.5 HNH endonuclease 5.3E-07 75-117 / 1-45
PF13391.5 HNH endonuclease 1E-06 75-118 / 1-46
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 3.5E-06 72-118 / 253-297
PF06147.10 Protein of unknown function (DUF968) 5E-06 71-117 / 126-174
PF16784.4 Putative HNHc nuclease 0.00047 71-117 / 122-171

Annotations of the NCBI proteins of this PHROG


2:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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