phrog_3277 is made of 44 protein sequences and is annotated as "DnaC-like helicase loader"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
118 299 101


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p17234 no NCBI prot ID no annotation VI_01038 Bacteroidia_gi_547939309 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p414308 no NCBI prot ID no annotation VI_05488 Bacteroidia_gi_282879408 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p30593 no NCBI prot ID no annotation VI_05486 Bacteroidia_gi_282879960_10239_76617 Viruses.
p413038 no NCBI prot ID no annotation VI_01156 Clostridia_gi_490540426 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p172455 no NCBI prot ID no annotation VI_05814 Clostridia_gi_544703850 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p55292 no NCBI prot ID no annotation VI_07981 Gammaproteobacteria_gi_419213154 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p226017 no NCBI prot ID no annotation VI_12003 Gammaproteobacteria_gi_327187809 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p267126 no NCBI prot ID no annotation VI_05328 Bacilli_gi_544790345 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p87653 no NCBI prot ID no annotation VI_10359 Gammaproteobacteria_gi_485838892 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p390344 no NCBI prot ID no annotation VI_10365 Gammaproteobacteria_gi_485839263 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p127799 no NCBI prot ID no annotation VI_03659 Gammaproteobacteria_gi_507080321_2524261_2566866 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p111959 no NCBI prot ID no annotation VI_07464 Gammaproteobacteria_gi_418254329 Viruses.
p310514 no NCBI prot ID no annotation VI_07088 Gammaproteobacteria_gi_325276083 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p419211 no NCBI prot ID no annotation VI_05318 Bacilli_gi_544736131 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p387840 no NCBI prot ID no annotation VI_06436 Gammaproteobacteria_gi_149113603 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p310136 no NCBI prot ID no annotation VI_10391 Gammaproteobacteria_gi_485848817 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bcepmuvirus.
p431071 no NCBI prot ID no annotation VI_10837 Gammaproteobacteria_gi_487392353 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; Escherichia virus HK630; Escherichia phage HK630.
p337905 no NCBI prot ID no annotation VI_10978 Gammaproteobacteria_gi_487551465 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p308668 no NCBI prot ID no annotation VI_06903 Gammaproteobacteria_gi_452274347 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p291949 no NCBI prot ID no annotation VI_10588 Gammaproteobacteria_gi_486086673 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bcepmuvirus.
p348169 no NCBI prot ID no annotation VI_10945 Gammaproteobacteria_gi_487517913 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p431817 no NCBI prot ID no annotation VI_11144 Gammaproteobacteria_gi_487681003 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p398698 no NCBI prot ID no annotation VI_10987 Gammaproteobacteria_gi_487561207 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p322427 no NCBI prot ID no annotation VI_10574 Gammaproteobacteria_gi_486047196 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bcepmuvirus.
p250099 no NCBI prot ID no annotation VI_10972 Gammaproteobacteria_gi_487540792 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p341396 no NCBI prot ID no annotation VI_10356 Gammaproteobacteria_gi_485838821 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bcepmuvirus.
p347983 no NCBI prot ID no annotation VI_10930 Gammaproteobacteria_gi_487501071 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p292119 no NCBI prot ID no annotation VI_10394 Gammaproteobacteria_gi_485849420 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bcepmuvirus.
p119849 no NCBI prot ID no annotation VI_10948 Gammaproteobacteria_gi_487522667 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p348650 no NCBI prot ID no annotation VI_10943 Gammaproteobacteria_gi_487513384 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p115025 no NCBI prot ID no annotation VI_10988 Gammaproteobacteria_gi_487562652 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p291838 no NCBI prot ID no annotation VI_10386 Gammaproteobacteria_gi_485847913 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Bcepmuvirus.
p30554 no NCBI prot ID no annotation VI_08144 Gammaproteobacteria_gi_419320257 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p434897 no NCBI prot ID no annotation VI_10357 Gammaproteobacteria_gi_485838828 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p422575 no NCBI prot ID no annotation VI_07323 Gammaproteobacteria_gi_417754031 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p189840 no NCBI prot ID no annotation VI_08194 Gammaproteobacteria_gi_419364337 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; Escherichia virus HK630; Escherichia phage HK630.
p432711 no NCBI prot ID no annotation VI_01891 Gammaproteobacteria_gi_422803715 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p400426 no NCBI prot ID no annotation VI_08183 Gammaproteobacteria_gi_419352924 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p170098 no NCBI prot ID no annotation VI_00749 Bacilli_gi_21909536_749188_788201 Viruses; unclassified bacterial viruses.
p163822 no NCBI prot ID no annotation VI_00757 Bacilli_gi_28894912_1107932_1147568 Viruses; unclassified bacterial viruses.
NC_004584_p12 NP_795384.1 Similar to E. coli DnaC protein NC_004584 Streptococcus phage 315.1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p145179 no NCBI prot ID no annotation VI_05454 Bacilli_gi_565885379 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p429702 no NCBI prot ID no annotation VI_04045 unknown_gi_546720379 Viruses.
p202159 no NCBI prot ID no annotation VI_12471 Spirochaetia_gi_545134079 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1528 98 holin lysis 5 6.39E-18 8.32
phrog_428 300 replication initiation protein DNA, RNA and nucleotide metabolism 4 2.95E-12 2.65
phrog_1174 128 no annotation unknown function 3 3.94E-11 1.53

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_14628 no annotation unknown function 93.6 0.0082 4-88 / 110-202
phrog_15321 no annotation unknown function 98.8 2.4E-12 2-83 / 7-88
phrog_26922 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 99.1 2.7E-14 2-74 / 11-78
phrog_27475 no annotation unknown function 99.9 1.3E-26 2-97 / 504-599
phrog_50 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 99.8 1.1E-23 2-86 / 174-254
phrog_6112 no annotation unknown function 99.7 5.3E-21 37-97 / 1-61

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00308.17 Bacterial dnaA protein 2.3E-08 101-126 / 33-58
PF13173.5 AAA domain 2.4E-08 102-124 / 3-25
PF06431.10 Polyomavirus large T antigen C-terminus 4E-08 100-127 / 154-181
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 7.8E-08 100-126 / 44-70
PF05673.12 Protein of unknown function (DUF815) 1.7E-07 101-126 / 54-79
PF12775.6 P-loop containing dynein motor region D3 1.9E-07 100-127 / 32-59
PF03969.15 AFG1-like ATPase 3.2E-07 100-126 / 66-92
PF12780.6 P-loop containing dynein motor region D4 3.7E-07 100-127 / 30-57
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 3.8E-07 101-127 / 32-58
PF13177.5 DNA polymerase III, delta subunit 3.8E-07 101-126 / 19-44
PF01695.16 IstB-like ATP binding protein 5.2E-07 101-126 / 48-73
PF07693.13 KAP family P-loop domain 6.7E-07 100-126 / 30-56
PF01078.20 Magnesium chelatase, subunit ChlI 7.1E-07 101-126 / 22-47
PF00519.16 Papillomavirus helicase 8.3E-07 100-126 / 261-287
PF00158.25 Sigma-54 interaction domain 1.5E-06 100-126 / 21-47
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 1.7E-06 103-125 / 2-24
PF05621.10 Bacterial TniB protein 1.8E-06 102-125 / 39-62
PF00004.28 ATPase family associated with various cellular activities (AAA) 1.9E-06 104-126 / 1-23
PF07726.10 ATPase family associated with various cellular activities (AAA) 2.1E-06 104-126 / 2-24
PF14516.5 AAA-like domain 2.2E-06 100-126 / 29-55
PF10443.8 RNA12 protein 2.5E-06 100-125 / 16-42
PF00493.22 MCM2/3/5 family 3.1E-06 101-127 / 57-83
PF07728.13 AAA domain (dynein-related subfamily) 3.2E-06 104-126 / 2-24
PF14532.5 Sigma-54 interaction domain 7.1E-06 101-126 / 21-46
PF07724.13 AAA domain (Cdc48 subfamily) 1.8E-05 101-125 / 3-27
PF13337.5 Putative ATP-dependent Lon protease 2E-05 100-126 / 205-231
PF07931.11 Chloramphenicol phosphotransferase-like protein 3.5E-05 102-126 / 2-26
PF08298.10 PrkA AAA domain 3.8E-05 101-126 / 85-110
PF00625.20 Guanylate kinase 3.9E-05 102-126 / 3-27
PF01637.17 ATPase domain predominantly from Archaea 4E-05 100-126 / 19-45
PF03215.14 Rad17 cell cycle checkpoint protein 5.1E-05 101-127 / 45-71
PF03976.13 Polyphosphate kinase 2 (PPK2) 5.9E-05 100-126 / 27-53
PF05970.13 PIF1-like helicase 6.4E-05 100-126 / 21-47
PF13671.5 AAA domain 7E-05 104-126 / 2-24
PF00910.21 RNA helicase 7E-05 104-126 / 1-23
PF13521.5 AAA domain 7.4E-05 104-125 / 2-23
PF01745.15 Isopentenyl transferase 8.6E-05 102-126 / 2-26
PF06414.11 Zeta toxin 8.9E-05 100-125 / 13-38
PF10649.8 Protein of unknown function (DUF2478) 8.8E-05 104-127 / 1-24
PF13238.5 AAA domain 0.0001 104-126 / 1-23
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.00012 101-126 / 4-29
PF05729.11 NACHT domain 0.00012 103-126 / 2-25
PF03266.14 NTPase 0.00013 104-125 / 2-23
PF13189.5 Cytidylate kinase-like family 0.00014 103-126 / 1-24
PF06144.12 DNA polymerase III, delta subunit 0.00015 104-252 / 1-148
PF01591.17 6-phosphofructo-2-kinase 0.00015 100-126 / 8-34
PF08433.9 Chromatin associated protein KTI12 0.00017 102-126 / 2-26
PF01712.18 Deoxynucleoside kinase 0.00018 104-126 / 1-23
PF05272.10 Virulence-associated protein E 0.00018 100-125 / 58-83
PF08303.10 tRNA ligase kinase domain 0.00019 104-126 / 2-24
PF01121.19 Dephospho-CoA kinase 0.00022 103-126 / 2-25
PF13401.5 AAA domain 0.00029 101-125 / 5-29
PF00485.17 Phosphoribulokinase / Uridine kinase family 0.0003 104-126 / 2-24
PF01443.17 Viral (Superfamily 1) RNA helicase 0.0003 104-124 / 1-20
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.00031 100-126 / 13-39
PF02223.16 Thymidylate kinase 0.00032 106-127 / 1-22
PF02224.17 Cytidylate kinase 0.00033 104-127 / 1-24
PF04851.14 Type III restriction enzyme, res subunit 0.00034 100-126 / 22-48
PF09820.8 Predicted AAA-ATPase 0.00035 101-126 / 31-56
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.00035 104-124 / 1-21
PF00931.21 NB-ARC domain 0.00038 100-125 / 19-44
PF13191.5 AAA ATPase domain 0.00038 102-126 / 25-49
PF13654.5 AAA domain 0.0059 105-125 / 272-292
PF10923.7 P-loop Domain of unknown function (DUF2791) 0.0005 100-126 / 48-74
PF04665.11 Poxvirus A32 protein 0.00054 100-126 / 12-38
PF04275.13 Phosphomevalonate kinase 0.00055 106-125 / 1-20
PF00265.17 Thymidine kinase 0.00056 102-126 / 2-26
PF09848.8 Uncharacterized conserved protein (DUF2075) 0.00059 102-125 / 2-25
PF03668.14 P-loop ATPase protein family 0.00076 102-123 / 2-23
PF00406.21 Adenylate kinase 0.00077 106-126 / 1-21
PF06068.12 TIP49 C-terminus 0.00082 101-126 / 50-75
PF01926.22 50S ribosome-binding GTPase 0.00091 104-124 / 2-22
PF13207.5 AAA domain 0.001 107-126 / 1-20
PF01583.19 Adenylylsulphate kinase 0.001 102-126 / 3-27
PF02562.15 PhoH-like protein 0.0011 101-124 / 19-42
PF01057.16 Parvovirus non-structural protein NS1 0.0011 101-125 / 118-142
PF13604.5 AAA domain 0.0012 104-124 / 19-40
PF07475.11 HPr Serine kinase C-terminal domain 0.0012 101-124 / 14-37
PF05707.11 Zonular occludens toxin (Zot) 0.0014 103-121 / 2-20
PF10236.8 Mitochondrial ribosomal death-associated protein 3 0.0015 100-126 / 23-49
PF13245.5 AAA domain 0.0016 101-126 / 11-36
PF13479.5 AAA domain 0.0017 102-123 / 3-24
PF13476.5 AAA domain 0.0018 102-126 / 21-45
PF06745.12 KaiC 0.0021 100-125 / 18-43
PF03796.14 DnaB-like helicase C terminal domain 0.0024 100-126 / 18-44
PF00437.19 Type II/IV secretion system protein 0.0024 101-127 / 130-156
PF13481.5 AAA domain 0.0026 101-125 / 28-52
PF07652.13 Flavivirus DEAD domain 0.0026 101-124 / 4-28
PF06309.10 Torsin 0.0028 102-126 / 53-77
PF00448.21 SRP54-type protein, GTPase domain 0.0029 103-126 / 3-26
PF07088.10 GvpD gas vesicle protein 0.0029 100-125 / 9-34
PF05127.13 Helicase 0.0031 105-126 / 1-22
PF09439.9 Signal recognition particle receptor beta subunit 0.0032 102-124 / 4-26
PF00154.20 recA bacterial DNA recombination protein 0.0034 100-125 / 51-76
PF11602.7 ATPase P4 of dsRNA bacteriophage phi-12 0.0034 100-126 / 121-147
PF02492.18 CobW/HypB/UreG, nucleotide-binding domain 0.0038 103-122 / 2-21
PF13086.5 AAA domain 0.0038 104-125 / 19-40
PF08423.10 Rad51 0.0039 100-125 / 36-61
PF13304.5 AAA domain, putative AbiEii toxin, Type IV TA system 0.0043 104-121 / 2-19
PF01580.17 FtsK/SpoIIIE family 0.005 101-125 / 38-62
PF10662.8 Ethanolamine utilisation - propanediol utilisation 0.0055 103-124 / 3-24
PF04670.11 Gtr1/RagA G protein conserved region 0.0061 104-124 / 2-22
PF00071.21 Ras family 0.0067 104-124 / 2-22
PF06048.10 Domain of unknown function (DUF927) 0.0071 101-127 / 188-214
PF03029.16 Conserved hypothetical ATP binding protein 0.0074 106-126 / 1-21
PF02421.17 Ferrous iron transport protein B 0.0085 104-124 / 2-22
PF01935.16 Domain of unknown function DUF87 0.0085 101-126 / 25-50

Annotations of the NCBI proteins of this PHROG


1:Similar to E. coli DnaC protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K02315 dnaC : DNA replication protein DnaC no pathways 334 10

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003924 GTPase activity
GO:0005524 ATP binding
GO:0006281 DNA repair
GO:0016301 kinase activity
GO:0008152 metabolic process
GO:0004003 ATP-dependent DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0006109 regulation of carbohydrate metabolic process
GO:0003723 RNA binding
GO:0008026 ATP-dependent helicase activity
GO:0004797 thymidine kinase activity
GO:0004631 phosphomevalonate kinase activity
GO:0005525 GTP binding
GO:0019079 viral genome replication
GO:0004672 protein kinase activity
GO:0009058 biosynthetic process
GO:0000155 phosphorelay sensor kinase activity
GO:0009360 DNA polymerase III complex
GO:0006139 nucleobase-containing compound metabolic process
GO:0019072 viral genome packaging
GO:0003724 RNA helicase activity
GO:0016020 membrane
GO:0051188 cofactor biosynthetic process
GO:0004140 dephospho-CoA kinase activity
GO:0016887 ATPase activity
GO:0006270 DNA replication initiation
GO:0000160 phosphorelay signal transduction system
GO:0006576 cellular biogenic amine metabolic process
GO:0043531 ADP binding
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0008134 transcription factor binding
GO:0009236 cobalamin biosynthetic process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0016740 transferase activity
GO:0000166 nucleotide binding
GO:0006000 fructose metabolic process
GO:0015937 coenzyme A biosynthetic process
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0004161 dimethylallyltranstransferase activity
GO:0006695 cholesterol biosynthetic process
GO:0004673 protein histidine kinase activity
GO:0003972 RNA ligase (ATP) activity
GO:0000723 telomere maintenance
GO:0003873 6-phosphofructo-2-kinase activity
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0003887 DNA-directed DNA polymerase activity
GO:0004127 cytidylate kinase activity
GO:0003678 DNA helicase activity
GO:0006260 DNA replication
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity

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