phrog_3312 is made of 43 protein sequences and is annotated as "endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
181.77 214 175


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KX610764_p97 AOT26070.1 G-I-Y Y-I-G endonuclease KX610764 Mycobacterium phage Kersh Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MF919502_p106 ATN88701.1 G-I-Y Y-I-G endonuclease MF919502 Mycobacterium phage Demsculpinboyz Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MG872841_p92 AVI04346.1 G-I-Y Y-I-G endonuclease MG872841 Mycobacterium phage Priscilla Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_026604_p90 YP_009125943.1 GIY-YIG endonuclease NC_026604 Mycobacterium phage Cerasum Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
JN020142_p94 AEJ93167.1 GIY-YIG homing endonuclease JN020142 Mycobacterium virus Mutaforma13 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_028923_p100 YP_009209649.1 GIY-YIG endonuclease NC_028923 Mycobacterium phage Llama Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
KY965064_p89 ASJ79681.1 G-I-Y-Y-I-G endonuclease KY965064 Mycobacterium phage Pippy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_021538_p93 YP_008126683.1 GIY-YIG endonuclease NC_021538 Mycobacterium phage Job42 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
KY702574_p100 ARM70687.1 GIY-YIG endonuclease KY702574 Mycobacterium phage Kingsley Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_028961_p84 YP_009214444.1 GIY-YIG DNA binding endonuclease NC_028961 Mycobacterium phage PopTart Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_028654_p101 YP_009187257.1 GIY-YIG endonuclease NC_028654 Mycobacterium phage Sparkdehlily Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MH020235_p91 AVP41746.1 hypothetical protein MH020235 Mycobacterium phage Batiatus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_028946_p91 YP_009212733.1 hypothetical protein NC_028946 Mycobacterium phage Dante Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_031262_p83 YP_009303922.1 GIY-YIG homing endonuclease NC_031262 Mycobacterium phage Brocalys Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MF190168_p90 ASR75834.1 GIY-YIG endonuclease MF190168 Mycobacterium phage Spoonbill Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_022060_p89 YP_008409626.1 GIY-YIG endonuclease NC_022060 Mycobacterium phage Velveteen Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_021301_p89 YP_008051215.1 GIY-YIG DNA binding domain from nucleotide excision repair endonuclease NC_021301 Mycobacterium phage SiSi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
KY348865_p87 APU93084.1 G-I-Y Y-I-G endonuclease KY348865 Mycobacterium phage Bubbles123 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023580_p89 YP_009007556.1 hypothetical protein NC_023580 Mycobacterium phage Saal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
JN020143_p94 AEJ93277.1 GIY-YIG endonuclease JN020143 Mycobacterium phage ShiLan Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; Mycobacterium virus Shilan.
NC_011287_p89 YP_002241673.1 gp89 NC_011287 Mycobacterium virus Pacc40 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
JN020141_p94 AEJ93063.1 GIY-YIG endonuclease JN020141 Mycobacterium phage Shauna1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; Mycobacterium virus Shauna1.
JF937102_p98 AEK09712.1 hypothetical protein JF937102 Mycobacterium virus Mozy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_028678_p88 YP_009189810.1 GIY-YIG endonuclease NC_028678 Mycobacterium phage Cabrinians Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
KY348865_p69 APU93067.1 G-I-Y Y-I-G endonuclease KY348865 Mycobacterium phage Bubbles123 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023580_p73 YP_009007540.1 GIY-YIG homing endonuclease NC_023580 Mycobacterium phage Saal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023698_p80 YP_009013175.1 gp80 NC_023698 Mycobacterium virus Avani Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_013936_p58 YP_003495200.1 gp59 NC_013936 Mycobacterium virus Ardmore Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
KX576644_p74 AOQ28527.1 G-I-Y Y-I-G endonuclease KX576644 Mycobacterium phage WillSterrel Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MG872841_p71 AVI04325.1 G-I-Y Y-I-G endonuclease MG872841 Mycobacterium phage Priscilla Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_022069_p81 YP_008410754.1 GIY-YIG endonuclease NC_022069 Mycobacterium phage Jabbawokkie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
JF937098_p71 AEK09167.1 DNA methylase JF937098 Mycobacterium virus Ibhubesi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_028844_p69 YP_009202586.1 GIY-YIG homing endonuclease NC_028844 Mycobacterium phage Phatniss Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MF190168_p70 ASR75814.1 GIY-YIG endonuclease MF190168 Mycobacterium phage Spoonbill Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023746_p68 YP_009018944.1 gp68 NC_023746 Mycobacterium virus Gumbie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
MH001448_p71 AVO21572.1 G-I-Y-Y-I-G endonuclease MH001448 Mycobacterium phage UncleRicky Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_008196_p68 YP_655064.1 gp68 NC_008196 Mycobacterium virus Llij Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_028792_p73 YP_009198177.1 GIY-YIG endonuclease NC_028792 Mycobacterium phage Kimberlium Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_031262_p65 YP_009303904.1 GIY-YIG homing endonuclease NC_031262 Mycobacterium phage Brocalys Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
KY965064_p70 ASJ79667.1 G-I-Y-Y-I-G endonuclease KY965064 Mycobacterium phage Pippy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023721_p69 YP_009016147.1 gp69 NC_023721 Mycobacterium virus Drago Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_028678_p72 YP_009189794.1 GIY-YIG nuclease NC_028678 Mycobacterium phage Cabrinians Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_028910_p69 YP_009208810.1 hypothetical protein NC_028910 Mycobacterium phage XFactor Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1467 102 no annotation unknown function 24 2.83E-79 69.67
phrog_6194 20 no annotation unknown function 20 0 1000
phrog_3171 46 replication initiation protein DNA, RNA and nucleotide metabolism 16 1.48E-57 47.95
phrog_1311 114 no annotation unknown function 12 9.17E-37 27.16
phrog_2070 73 no annotation unknown function 6 9.18E-20 10.16
phrog_2247 67 no annotation unknown function 3 5.93E-11 1.35

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_16880 endonuclease DNA, RNA and nucleotide metabolism 99.7 1.2E-21 1-78 / 2-79
phrog_26247 no annotation unknown function 92.0 0.026 128-167 / 18-53
phrog_314 homing endonuclease DNA, RNA and nucleotide metabolism 92.4 0.02 5-78 / 2-86
phrog_35456 no annotation unknown function 94.4 0.0037 7-78 / 6-83

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01541.23 GIY-YIG catalytic domain 2.9E-10 19-84 / 2-79
PF09517.9 Eco29kI restriction endonuclease 1.3E-08 17-90 / 3-116
PF00392.20 Bacterial regulatory proteins, gntR family 0.0025 159-198 / 27-58
PF15977.4 Winged helix-turn-helix DNA binding 0.0031 161-198 / 28-57
PF01726.15 LexA DNA binding domain 0.0034 159-199 / 28-61
PF04492.12 Bacteriophage replication protein O 0.0044 159-198 / 52-83
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.0051 159-198 / 25-56
PF09012.9 FeoC like transcriptional regulator 0.0054 159-198 / 17-48
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0058 159-197 / 26-56
PF08222.10 CodY helix-turn-helix domain 0.0065 160-197 / 8-37

Annotations of the NCBI proteins of this PHROG


14:GIY-YIG endonuclease 9:hypothetical protein 7:G-I-Y Y-I-G endonuclease 5:GIY-YIG homing endonuclease 3:G-I-Y-Y-I-G endonuclease 1:GIY-YIG DNA binding endonuclease 1:GIY-YIG domain 1:DNA methylase 1:GIY-YIG DNA binding domain from nucleotide excision repair endonuclease 1:GIY-YIG nuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004252 serine-type endopeptidase activity
GO:0005667 transcription factor complex
GO:0006508 proteolysis
GO:0006260 DNA replication
GO:0003700 DNA binding transcription factor activity
GO:0006355 regulation of transcription, DNA-templated

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