phrog_3359 is made of 43 protein sequences and is annotated as "NAD-dependent DNA ligase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
326.3 577 323


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_031933_p125 YP_009323854.1 DNA ligase NC_031933 Salmonella phage 118970_sal2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Epseptimavirus.
KR422353_p111 AKO61512.1 NAD-dependent DNA ligase, subunit A KR422353 Escherichia phage APCEc03 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; Escherichia virus phiAPCEc03.
MH102285_p33 AVQ09870.1 DNA ligase MH102285 Salmonella phage vB_SenS_PHB06 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; unclassified Tequintavirus.
KY963424_p111 ASD50284.1 NAD-dependent DNA ligase subunit A KY963424 Shigella phage SSP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; Shigella virus SSP1.
KY787212_p132 ARM69795.1 NAD-dependent DNA ligase subunit A KY787212 Salmonella phage BSP22A Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Epseptimavirus; unclassified Epseptimavirus.
MG649966_p62 AUG85069.1 NAD-dependent DNA ligase subunit A MG649966 Vibrio virus Ceto Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Ermolyevavirinae; Cetovirus.
KX845404_p100 AOZ65432.1 NAD-dependent DNA ligase subunit A KX845404 Klebsiella phage vB_Kpn_IME260 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Sugarlandvirus; Klebsiella virus IME260.
MF431735_p113 ASU02325.1 DNA ligase MF431735 Bacteriophage T5-like poul124 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; unclassified Tequintavirus.
NC_028840_p87 YP_009202133.1 DNA ligase NC_028840 Escherichia phage slur09 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus.
KY883654_p68 ASV43437.1 DNA ligase KY883654 Vibrio phage JSF10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Ermolyevavirinae; Jesfedecavirus; Vibrio virus JSF10.
NC_028754_p105 YP_009194749.1 NAD-dependent DNA ligase, subunit A NC_028754 Salmonella phage Shivani Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus.
MG676225_p69 AVR76105.1 DNA ligase MG676225 Aeromonas phage AhSzw-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Shenzhenvirus; Aeromonas virus AhSzw1.
NC_028895_p105 YP_009207570.1 hypothetical protein NC_028895 Vibrio phage phi 3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Ermolyevavirinae; Jesfedecavirus; Vibrio virus phi3.
AY587007_p107 AAX12044.1 DNA ligase AY587007 Escherichia virus T5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus.
MF402939_p63 ASM62923.1 NAD-dependent DNA ligase subunit A MF402939 Escherichia phage OSYSP Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; Escherichia virus OSYSP.
p285731 no NCBI prot ID no annotation VI_00003 SUP05_AB_751_G10AB_905_6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_031022_p120 YP_009280307.1 DNA ligase NC_031022 Shigella phage SHSML-45 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; Shigella virus SHSML45.
NC_027356_p92 YP_009149873.1 NAD-dependent DNA ligase subunit A NC_027356 Escherichia virus DT57C Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus.
NC_017969_p119 YP_006382418.1 NAD-dependent DNA ligase subunit A NC_017969 Escherichia virus AKFV33 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus.
KY114934_p54 ATI99411.1 DNA ligase KY114934 Salmonella phage SP01 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; Salmonella virus SP01.
NC_018837_p111 YP_006906363.1 putative NAD-dependent DNA ligase subunit A NC_018837 Pectobacterium phage My1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Mccorquodalevirinae; Myunavirus; Pectobacterium virus My1.
MF001363_p60 ASZ77812.1 DNA ligase MF001363 Salmonella phage SH9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Epseptimavirus; Salmonella virus SH9.
KY677846_p18 ARB06847.1 NAD-dependent DNA ligase subunit A KY677846 Escherichia phage phiLLS Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; Escherichia virus phiLLS.
MG459987_p130 ATW61967.1 NAD-dependent DNA ligase subunit A MG459987 Klebsiella phage Sugarland Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Sugarlandvirus; Klebsiella virus Sugarland.
KM979355_p92 AJA41745.1 NAD-dependent DNA ligase large subunit KM979355 Enterobacteria phage DT571/2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; unclassified Tequintavirus.
NC_027297_p123 YP_009146064.1 NAD-dependent DNA ligase, subunit A NC_027297 Salmonella virus Stitch Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Epseptimavirus.
NC_031042_p48 YP_009283389.1 NDP-dependent DNA ligase subunit A NC_031042 Salmonella phage NR01 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus; Salmonella virus NR01.
NC_005859_p116 YP_006944.1 NAD-dependent DNA ligase, subunit A NC_005859 Escherichia virus T5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus.
NC_010583_p130 YP_001837053.1 NAD-dependent DNA ligase subunit A NC_010583 Escherichia virus EPS7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Epseptimavirus.
NC_031902_p130 YP_009320854.1 DNA ligase NC_031902 Salmonella phage 100268_sal2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Epseptimavirus.
KT345706_p32 AKY02233.1 NAD-dependent DNA subunit A KT345706 Vibrio phage vB_VorS-PVo5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Ermolyevavirinae; Cetovirus; unclassified Cetovirus.
MG030347_p39 ATW69922.1 DNA ligase subunit A MG030347 Proteus phage PM135 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Novosibvirus; Proteus virus PM135.
NC_024139_p115 YP_009031736.1 NAD-dependent DNA ligase, subunit A NC_024139 Escherichia phage vB_EcoS_FFH1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus.
KY363465_p118 AQT25224.1 DNA ligase KY363465 Providencia phage vB_PreS_PR1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Priunavirus; Providencia virus PR1.
NC_019529_p21 YP_007007844.1 NAD-dependent DNA ligase subunit A NC_019529 Vibrio phage pVp-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Ermolyevavirinae; Vipunavirus; Vibrio virus pVp1.
MF431736_p118 ASU02481.1 DNA ligase MF431736 Bacteriophage T5-like chee130_1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Epseptimavirus; unclassified Epseptimavirus.
NC_019919_p113 YP_007237087.1 DNA ligase, phage-associated NC_019919 Yersinia phage phiR201 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Haartmanvirus; Yersinia virus phiR201.
MF979564_p91 ATS94075.1 putative NAD-dependent DNA ligase subunit A MF979564 Pectobacterium phage DU_PP_V Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Mccorquodalevirinae; Hongcheonvirus; Pectobacterium virus DUPPV.
NC_015269_p107 YP_004306590.1 NAD-dependent DNA ligase subunit A NC_015269 Salmonella virus SPC35 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Markadamsvirinae; Tequintavirus.
MG649967_p60 AUG85262.1 NAD-dependent DNA ligase subunit A MG649967 Vibrio virus Thalassa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Ermolyevavirinae; Cetovirus.
NC_010821_p327 YP_001957053.1 putative DNA ligase NC_010821 Pseudomonas phage 201phi2-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Phikzvirus; unclassified Phikzvirus.
MF042360_p331 ARV76962.1 putative DNA ligase MF042360 Pseudomonas phage Phabio Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Phikzvirus; unclassified Phikzvirus.
NC_009817_p11 YP_001469010.1 gp012 NC_009817 Lactococcus virus KSY1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3498 41 NAD-dependent DNA ligase DNA, RNA and nucleotide metabolism 32 1.75E-128 118.88
phrog_8267 14 no annotation unknown function 14 0 1000
phrog_4053 34 transcriptional regulator transcription regulation 11 1.42E-40 30.97
phrog_19164 4 no annotation unknown function 4 0 1000
phrog_23191 3 no annotation unknown function 3 0 1000
phrog_13916 7 DNA ligase DNA, RNA and nucleotide metabolism 2 2.95E-11 1.65
phrog_35018 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_3869 NAD-dependent DNA ligase DNA, RNA and nucleotide metabolism 100.0 1.1E-63 1-322 / 9-383

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01653.17 NAD-dependent DNA ligase adenylation domain 3.7E-53 9-271 / 2-318
PF03120.15 NAD-dependent DNA ligase OB-fold domain 3.9E-17 274-347 / 1-74
PF11731.7 Pathogenicity locus 0.004 421-478 / 7-63
PF14520.5 Helix-hairpin-helix domain 0.006 421-476 / 3-57

Annotations of the NCBI proteins of this PHROG


16:DNA ligase 15:NAD-dependent DNA ligase subunit A 5:NAD-dependent DNA ligase, subunit A 1:DNA ligase, phage-associated 1:NAD-dependent DNA ligase large subunit 1:NDP-dependent DNA ligase subunit A 1:hypothetical protein 1:NAD-dependent DNA subunit A 1:DNA ligase subunit A

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K01972 E6.5.1.2, ligA, ligB : DNA ligase (NAD+) [EC:6.5.1.2] ko03030 DNA replication
ko03410 Base excision repair
ko03420 Nucleotide excision repair
ko03430 Mismatch repair
155 41

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003911 DNA ligase (NAD+) activity
GO:0006281 DNA repair
GO:0006260 DNA replication

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