phrog_3445 is made of 42 protein sequences and is annotated as "toxin"
Functional category: moron, auxiliary metabolic gene and host takeover


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
117.21 206 99


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p70292 no NCBI prot ID no annotation VI_05591 Betaproteobacteria_gi_482909684_27294_76934 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p326175 no NCBI prot ID no annotation VI_10072 Gammaproteobacteria_gi_555264907 Viruses.
p164809 no NCBI prot ID no annotation VI_02560 Gammaproteobacteria_gi_490893321 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Peduovirus.
NC_031264_p20 YP_009304048.1 addiction module antitoxin/toxin NC_031264 Brucella phage BiPBO1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p43185 no NCBI prot ID no annotation VI_02599 Gammaproteobacteria_gi_425064754_759240_819141 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p20275 no NCBI prot ID no annotation VI_03506 Gammaproteobacteria_gi_514965089 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p225152 no NCBI prot ID no annotation VI_12183 Gammaproteobacteria_gi_545595213_260_34541 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p169017 no NCBI prot ID no annotation VI_01095 Betaproteobacteria_gi_386860126_133514_172629 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Peduovirus.
p109702 no NCBI prot ID no annotation VI_00077 Alphaproteobacteria_gi_307944653 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p204983 no NCBI prot ID no annotation VI_00022 Actinobacteria_gi_223955933_488_36693 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p259922 no NCBI prot ID no annotation VI_06606 Gammaproteobacteria_gi_294665708 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p152104 no NCBI prot ID no annotation VI_05530 Betaproteobacteria_gi_149156765_2958_43574 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Peduovirus.
p413085 no NCBI prot ID no annotation VI_05599 Betaproteobacteria_gi_483606617 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p416192 no NCBI prot ID no annotation VI_05504 Betaproteobacteria_gi_134283347_137806_150093 Viruses.
p211386 no NCBI prot ID no annotation VI_01119 Betaproteobacteria_gi_53721039_1426445_1462145 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Peduovirus.
p341574 no NCBI prot ID no annotation VI_01053 Betaproteobacteria_gi_254192738_549538_570582 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Peduovirus.
p394821 no NCBI prot ID no annotation VI_05536 Betaproteobacteria_gi_149161195 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Tigrvirus; Burkholderia virus phiE122.
NC_009236_p7 YP_001111157.1 gp7, putative addiction module killer protein NC_009236 Burkholderia virus phiE122 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae; Tigrvirus.
p7375 no NCBI prot ID no annotation VI_02970 Gammaproteobacteria_gi_510944733 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p1184 no NCBI prot ID no annotation VI_02973 Gammaproteobacteria_gi_162417821 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p80257 no NCBI prot ID no annotation VI_11914 Gammaproteobacteria_gi_565824023 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p80673 no NCBI prot ID no annotation VI_07918 Gammaproteobacteria_gi_419145794 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p80178 no NCBI prot ID no annotation VI_01441 Gammaproteobacteria_gi_545169252 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p20272 no NCBI prot ID no annotation VI_03506 Gammaproteobacteria_gi_514965089 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p87152 no NCBI prot ID no annotation VI_01616 Gammaproteobacteria_gi_545246407 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p75558 no NCBI prot ID no annotation VI_02384 Gammaproteobacteria_gi_476538191 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p109973 no NCBI prot ID no annotation VI_12375 Spirochaetia_gi_470008191 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p71660 no NCBI prot ID no annotation VI_10940 Gammaproteobacteria_gi_487507756 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p212645 no NCBI prot ID no annotation VI_05731 Betaproteobacteria_gi_565867306 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p70170 no NCBI prot ID no annotation VI_01922 Gammaproteobacteria_gi_423710565 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p75621 no NCBI prot ID no annotation VI_02960 Gammaproteobacteria_gi_510917659 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p119516 no NCBI prot ID no annotation VI_11143 Gammaproteobacteria_gi_490206926_2997_46550 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p75407 no NCBI prot ID no annotation VI_10934 Gammaproteobacteria_gi_487504222 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p329208 no NCBI prot ID no annotation VI_06416 Gammaproteobacteria_gi_145629842 Viruses.
p148570 no NCBI prot ID no annotation VI_02305 Gammaproteobacteria_gi_476380574 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p1175 no NCBI prot ID no annotation VI_02973 Gammaproteobacteria_gi_162417821 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p80223 no NCBI prot ID no annotation VI_11908 Gammaproteobacteria_gi_565823102 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p148517 no NCBI prot ID no annotation VI_02951 Gammaproteobacteria_gi_510912741 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p48194 no NCBI prot ID no annotation VI_06444 Gammaproteobacteria_gi_156105548 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p385797 no NCBI prot ID no annotation VI_07618 Gammaproteobacteria_gi_418801094 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.
p81556 no NCBI prot ID no annotation VI_04253 Alphaproteobacteria_gi_421760367 Viruses.
p262060 no NCBI prot ID no annotation VI_10017 Gammaproteobacteria_gi_555241789 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Punavirus; Escherichia virus P1.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_4268 32 transcriptional repressor transcription regulation 22 6.75E-89 79.29
phrog_2339 64 HTH DNA binding protein DNA, RNA and nucleotide metabolism 19 2.31E-67 57.76
phrog_4595 29 no annotation unknown function 13 1.35E-50 40.99
phrog_6456 19 no annotation unknown function 5 6.80E-21 11.29

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1213 RelE-like toxin moron, auxiliary metabolic gene and host takeover 93.6 0.0078 1-72 / 2-72
phrog_2523 no annotation unknown function 98.9 7.4E-13 1-98 / 1-105

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF15781.4 ParE-like toxin of type II bacterial toxin-antitoxin system 1.5E-05 79-156 / 1-80
PF05973.13 Phage derived protein Gp49-like (DUF891) 2.8E-05 88-168 / 2-86
PF15738.4 Bacterial toxin of type II toxin-antitoxin system, YafQ 3E-05 77-156 / 1-85
PF06769.13 YoeB-like toxin of bacterial type II toxin-antitoxin system 5.5E-05 81-153 / 1-79
PF11663.7 Toxin with endonuclease activity, of toxin-antitoxin system 0.00065 97-152 / 37-99
PF06296.11 RelE toxin of RelE / RelB toxin-antitoxin system 0.00086 77-157 / 1-82
PF05016.14 ParE toxin of type II toxin-antitoxin system, parDE 0.0023 79-155 / 1-85
PF05015.12 RelE-like toxin of type II toxin-antitoxin system HigB 0.0074 91-144 / 20-82

Annotations of the NCBI proteins of this PHROG


1:addiction module antitoxin/toxin 1:gp7, addiction module killer protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004540 ribonuclease activity
GO:0004519 endonuclease activity
GO:0006401 RNA catabolic process
GO:0110001 toxin-antitoxin complex

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