phrog_34481 is made of 2 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
130 132 132


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_019725_p65 YP_007112732.1 hypothetical protein NC_019725 Escherichia phage ADB-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Drexlerviridae; Tunavirinae; Tunavirus.
NC_029071_p67 YP_009223489.1 hypothetical protein NC_029071 Salmonella phage 36 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Drexlerviridae; Tempevirinae; Tlsvirus; Salmonella virus 36.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_16 2054 DNA helicase DNA, RNA and nucleotide metabolism 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_16 DNA helicase DNA, RNA and nucleotide metabolism 97.2 1.7E-06 30-110 / 2-71

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04851.14 Type III restriction enzyme, res subunit 3.4E-08 30-88 / 3-61
PF13086.5 AAA domain 8.6E-08 31-97 / 2-66
PF07652.13 Flavivirus DEAD domain 9.9E-07 50-100 / 4-55
PF02562.15 PhoH-like protein 1E-06 30-88 / 4-59
PF00580.20 UvrD/REP helicase N-terminal domain 2.2E-06 32-98 / 2-65
PF00270.28 DEAD/DEAH box helicase 2.5E-06 33-99 / 2-66
PF13872.5 P-loop containing NTP hydrolase pore-1 2.6E-06 29-101 / 34-112
PF09848.8 Uncharacterized conserved protein (DUF2075) 2.9E-06 51-94 / 2-46
PF07517.13 SecA DEAD-like domain 4.9E-06 29-100 / 89-153
PF05970.13 PIF1-like helicase 5.5E-06 31-88 / 2-60
PF00176.22 SNF2 family N-terminal domain 6.5E-06 34-101 / 1-105
PF12340.7 Protein of unknown function (DUF3638) 6.6E-06 27-100 / 19-87
PF06862.11 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 2.3E-05 33-102 / 2-110
PF02399.14 Origin of replication binding protein 2.4E-05 50-100 / 49-100
PF12775.6 P-loop containing dynein motor region D3 2.9E-05 50-74 / 33-57
PF13245.5 AAA domain 2.9E-05 50-87 / 11-48
PF05127.13 Helicase 3.2E-05 54-91 / 1-40
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 5.5E-05 52-86 / 2-36
PF01695.16 IstB-like ATP binding protein 5.8E-05 50-74 / 48-72
PF00308.17 Bacterial dnaA protein 6E-05 50-74 / 33-57
PF05729.11 NACHT domain 6.4E-05 52-74 / 2-24
PF13604.5 AAA domain 7.2E-05 31-70 / 2-36
PF00437.19 Type II/IV secretion system protein 0.00012 50-75 / 130-155
PF10412.8 Type IV secretion-system coupling protein DNA-binding domain 0.00013 50-89 / 15-54
PF00158.25 Sigma-54 interaction domain 0.00013 50-74 / 22-46
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.00014 50-75 / 4-29
PF10649.8 Protein of unknown function (DUF2478) 0.00014 53-76 / 1-24
PF13173.5 AAA domain 0.00016 51-73 / 3-25
PF00265.17 Thymidine kinase 0.00018 52-86 / 3-37
PF00625.20 Guanylate kinase 0.00019 51-74 / 3-26
PF12846.6 AAA-like domain 0.00019 50-89 / 21-60
PF01935.16 Domain of unknown function DUF87 0.00019 50-88 / 25-72
PF07931.11 Chloramphenicol phosphotransferase-like protein 0.0002 52-74 / 3-25
PF01078.20 Magnesium chelatase, subunit ChlI 0.00024 50-74 / 22-46
PF03976.13 Polyphosphate kinase 2 (PPK2) 0.00024 50-74 / 28-52
PF13177.5 DNA polymerase III, delta subunit 0.00024 50-74 / 19-43
PF14516.5 AAA-like domain 0.00026 50-75 / 30-55
PF01637.17 ATPase domain predominantly from Archaea 0.00026 50-75 / 20-45
PF06745.12 KaiC 0.00026 50-84 / 19-53
PF01745.15 Isopentenyl transferase 0.00026 52-74 / 3-25
PF05872.11 Bacterial protein of unknown function (DUF853) 0.00026 50-88 / 21-59
PF03266.14 NTPase 0.00027 53-74 / 2-23
PF13671.5 AAA domain 0.00027 53-73 / 2-22
PF06431.10 Polyomavirus large T antigen C-terminus 0.00028 50-74 / 155-179
PF06414.11 Zeta toxin 0.0003 50-74 / 14-38
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.0003 53-72 / 1-20
PF14617.5 U3-containing 90S pre-ribosomal complex subunit 0.00032 50-101 / 77-141
PF00910.21 RNA helicase 0.00032 54-74 / 2-22
PF12780.6 P-loop containing dynein motor region D4 0.00034 49-72 / 30-53
PF13401.5 AAA domain 0.00034 50-74 / 5-29
PF05621.10 Bacterial TniB protein 0.00036 51-74 / 39-62
PF05673.12 Protein of unknown function (DUF815) 0.00037 50-74 / 54-78
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 0.00039 50-73 / 45-68
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 0.00039 50-73 / 32-55
PF13238.5 AAA domain 0.0004 53-74 / 1-22
PF13521.5 AAA domain 0.00041 53-73 / 2-22
PF08433.9 Chromatin associated protein KTI12 0.00043 52-75 / 3-26
PF00154.20 recA bacterial DNA recombination protein 0.0005 50-84 / 52-86
PF01712.18 Deoxynucleoside kinase 0.00057 53-74 / 1-22
PF03969.15 AFG1-like ATPase 0.00058 50-74 / 67-91
PF04665.11 Poxvirus A32 protein 0.0006 50-74 / 13-37
PF07728.13 AAA domain (dynein-related subfamily) 0.0006 53-74 / 2-23
PF07726.10 ATPase family associated with various cellular activities (AAA) 0.00067 53-74 / 2-23
PF01443.17 Viral (Superfamily 1) RNA helicase 0.00068 53-71 / 1-19
PF03215.14 Rad17 cell cycle checkpoint protein 0.00068 50-74 / 45-69
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.0007 50-74 / 14-38
PF03796.14 DnaB-like helicase C terminal domain 0.00072 50-85 / 19-55
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.00077 54-74 / 2-22
PF00485.17 Phosphoribulokinase / Uridine kinase family 0.00078 53-74 / 2-23
PF09820.8 Predicted AAA-ATPase 0.00082 50-74 / 31-55
PF01591.17 6-phosphofructo-2-kinase 0.00083 50-74 / 9-33
PF02223.16 Thymidylate kinase 0.00087 55-74 / 1-20
PF02534.13 Type IV secretory system Conjugative DNA transfer 0.0009 50-91 / 43-82
PF05707.11 Zonular occludens toxin (Zot) 0.00092 53-70 / 3-20
PF13189.5 Cytidylate kinase-like family 0.00092 53-74 / 2-23
PF08303.10 tRNA ligase kinase domain 0.00094 53-73 / 2-22
PF07724.13 AAA domain (Cdc48 subfamily) 0.00098 51-74 / 4-27
PF01121.19 Dephospho-CoA kinase 0.00098 53-73 / 3-23
PF07693.13 KAP family P-loop domain 0.00099 50-74 / 31-55
PF09807.8 Elongation complex protein 6 0.001 50-87 / 18-54
PF04275.13 Phosphomevalonate kinase 0.001 55-74 / 1-20
PF05272.10 Virulence-associated protein E 0.0011 50-73 / 59-82
PF13191.5 AAA ATPase domain 0.0011 51-74 / 25-48
PF08423.10 Rad51 0.0011 50-74 / 37-61
PF10923.7 P-loop Domain of unknown function (DUF2791) 0.0013 50-75 / 49-74
PF00493.22 MCM2/3/5 family 0.0013 51-73 / 58-80
PF00448.21 SRP54-type protein, GTPase domain 0.0014 52-84 / 3-36
PF00519.16 Papillomavirus helicase 0.0015 50-73 / 262-285
PF14532.5 Sigma-54 interaction domain 0.0016 50-73 / 21-44
PF13481.5 AAA domain 0.0017 50-73 / 28-51
PF16575.4 mRNA cleavage and polyadenylation factor CLP1 P-loop 0.0018 57-84 / 1-28
PF02224.17 Cytidylate kinase 0.0018 54-74 / 2-22
PF00406.21 Adenylate kinase 0.0018 55-73 / 1-19
PF10236.8 Mitochondrial ribosomal death-associated protein 3 0.0019 50-75 / 24-49
PF01583.19 Adenylylsulphate kinase 0.0021 51-74 / 3-26
PF13337.5 Putative ATP-dependent Lon protease 0.0022 50-73 / 206-229
PF07088.10 GvpD gas vesicle protein 0.0023 50-85 / 10-44
PF04466.12 Phage terminase large subunit 0.0023 52-90 / 3-45
PF10443.8 RNA12 protein 0.0027 50-73 / 17-41
PF00931.21 NB-ARC domain 0.0029 50-74 / 20-44
PF01926.22 50S ribosome-binding GTPase 0.003 53-73 / 2-22
PF13654.5 AAA domain 0.003 50-74 / 24-48
PF03846.13 Cell division inhibitor SulA 0.0031 50-90 / 23-65
PF03029.16 Conserved hypothetical ATP binding protein 0.0033 55-75 / 1-21
PF13207.5 AAA domain 0.0036 56-73 / 1-18
PF13476.5 AAA domain 0.0036 50-73 / 20-43
PF13479.5 AAA domain 0.0039 51-71 / 3-23
PF01057.16 Parvovirus non-structural protein NS1 0.0041 50-73 / 118-141
PF11602.7 ATPase P4 of dsRNA bacteriophage phi-12 0.0042 50-74 / 122-146
PF03668.14 P-loop ATPase protein family 0.0043 52-72 / 3-23
PF06068.12 TIP49 C-terminus 0.0044 50-74 / 50-74
PF03354.14 Phage Terminase 0.0051 50-92 / 23-69
PF07475.11 HPr Serine kinase C-terminal domain 0.0052 50-72 / 14-36
PF01580.17 FtsK/SpoIIIE family 0.0069 50-73 / 38-61
PF05876.11 Phage terminase large subunit (GpA) 0.0079 29-94 / 22-85
PF13304.5 AAA domain, putative AbiEii toxin, Type IV TA system 0.0082 53-70 / 2-19
PF09439.9 Signal recognition particle receptor beta subunit 0.0085 51-73 / 4-26

Annotations of the NCBI proteins of this PHROG


2:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003723 RNA binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0006109 regulation of carbohydrate metabolic process
GO:0003697 single-stranded DNA binding
GO:0006281 DNA repair
GO:0016301 kinase activity
GO:0008152 metabolic process
GO:0005524 ATP binding
GO:0009291 unidirectional conjugation
GO:0009058 biosynthetic process
GO:0000155 phosphorelay sensor kinase activity
GO:0004672 protein kinase activity
GO:0019079 viral genome replication
GO:0004631 phosphomevalonate kinase activity
GO:0005525 GTP binding
GO:0009432 SOS response
GO:0008026 ATP-dependent helicase activity
GO:0004797 thymidine kinase activity
GO:0015937 coenzyme A biosynthetic process
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0003676 nucleic acid binding
GO:0006000 fructose metabolic process
GO:0000166 nucleotide binding
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0016740 transferase activity
GO:0000160 phosphorelay signal transduction system
GO:0043531 ADP binding
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0005634 nucleus
GO:0008134 transcription factor binding
GO:0009236 cobalamin biosynthetic process
GO:0051782 negative regulation of cell division
GO:0033588 Elongator holoenzyme complex
GO:0006270 DNA replication initiation
GO:0004140 dephospho-CoA kinase activity
GO:0016887 ATPase activity
GO:0051188 cofactor biosynthetic process
GO:0019072 viral genome packaging
GO:0003724 RNA helicase activity
GO:0006139 nucleobase-containing compound metabolic process
GO:0017038 protein import
GO:0016020 membrane
GO:0002098 tRNA wobble uridine modification
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0004127 cytidylate kinase activity
GO:0006260 DNA replication
GO:0003678 DNA helicase activity
GO:0003873 6-phosphofructo-2-kinase activity
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0003688 DNA replication origin binding
GO:0000723 telomere maintenance
GO:0003972 RNA ligase (ATP) activity
GO:0004673 protein histidine kinase activity
GO:0004161 dimethylallyltranstransferase activity
GO:0006695 cholesterol biosynthetic process
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0043752 adenosylcobinamide kinase activity

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