phrog_35175 is made of 2 protein sequences and is annotated as "HNH endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
262 262 262


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_025447_p163 YP_009101757.1 HNH endonuclease NC_025447 Escherichia phage 121Q Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Asteriusvirus; Escherichia virus 121Q.
NC_027364_p353 YP_009150667.1 hypothetical protein NC_027364 Escherichia phage PBECO 4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Asteriusvirus; Escherichia virus PBECO4.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_28392 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0021 37-113 / 9-61
phrog_1571 HNH endonuclease DNA, RNA and nucleotide metabolism 94.5 0.0029 40-110 / 15-83
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 91.6 0.032 39-124 / 75-138
phrog_16986 no annotation unknown function 90.7 0.05 37-61 / 13-37
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 94.8 0.0021 25-131 / 18-90
phrog_23285 HNH endonuclease DNA, RNA and nucleotide metabolism 95.2 0.001 44-125 / 48-133
phrog_25420 HNH endonuclease DNA, RNA and nucleotide metabolism 99.8 5.6E-23 10-149 / 7-148
phrog_25983 HNH endonuclease DNA, RNA and nucleotide metabolism 98.1 5.3E-09 77-143 / 30-95
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0042 39-112 / 45-95
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 90.4 0.054 43-114 / 4-52
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 90.3 0.058 38-134 / 62-125

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13395.5 HNH endonuclease 6.1E-07 82-117 / 17-52
PF05315.10 ICEA Protein 7.6E-07 29-117 / 78-151
PF01844.22 HNH endonuclease 1.6E-06 83-115 / 12-47
PF05766.11 Bacteriophage Lambda NinG protein 3.7E-06 32-117 / 74-137
PF13391.5 HNH endonuclease 5.2E-06 82-117 / 11-46
PF14279.5 HNH endonuclease 6.2E-06 82-117 / 12-46
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 5.3E-05 83-119 / 264-299
PF06147.10 Protein of unknown function (DUF968) 0.00016 83-116 / 138-174

Annotations of the NCBI proteins of this PHROG


1:HNH endonuclease 1:hypothetical protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004519 endonuclease activity
GO:0003676 nucleic acid binding

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