phrog_35548 is made of 2 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
166 166 166


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KY389064_p53 AQN32284.1 cell division protein KY389064 Staphylococcus phage phi879 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Biseptimavirus; unclassified Biseptimavirus.
KY389063_p55 AQN32228.1 ZipA protein KY389063 Staphylococcus phage phi575 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Biseptimavirus; unclassified Biseptimavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
no colocalized PHROGS                                                                                          

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 95.5 0.00053 5-62 / 14-72
phrog_139 deoxynucleoside monophosphate kinase other 93.2 0.011 6-35 / 3-32
phrog_168 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 95.1 0.0013 9-31 / 42-64
phrog_1815 guanylate kinase other 95.1 0.0012 6-25 / 3-22
phrog_19 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 90.5 0.053 4-45 / 196-246
phrog_2071 ATPase other 97.5 2.5E-07 5-120 / 3-113
phrog_2107 thymidylate kinase other 93.7 0.0076 7-43 / 5-47
phrog_2392 ABC transporter moron, auxiliary metabolic gene and host takeover 90.2 0.06 5-26 / 369-390
phrog_26606 no annotation unknown function 93.4 0.0097 6-28 / 133-155
phrog_2666 terminase large subunit head and packaging 90.3 0.056 8-26 / 10-28
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 94.3 0.0041 5-28 / 38-61
phrog_296 DNA transposition protein integration and excision 92.6 0.018 4-31 / 90-117
phrog_505 polynucleotide kinase other 96.3 7.4E-05 6-124 / 3-123
phrog_50 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 94.1 0.0052 6-31 / 113-137
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 92.7 0.016 5-69 / 38-119
phrog_592 thymidine kinase other 94.9 0.0016 71-107 / 110-144
phrog_6931 no annotation unknown function 95.5 0.00054 5-125 / 187-310
phrog_7485 no annotation unknown function 94.2 0.0045 6-59 / 228-291
phrog_761 thymidylate kinase other 96.6 2.6E-05 5-127 / 2-138
phrog_77 SbcC-like subunit of palindrome specific endonuclease DNA, RNA and nucleotide metabolism 91.1 0.041 50-98 / 112-161
phrog_800 terminase small subunit head and packaging 94.5 0.0032 4-31 / 7-34

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13671.5 AAA domain 1.8E-15 7-125 / 1-121
PF06414.11 Zeta toxin 4.2E-15 3-126 / 12-141
PF08433.9 Chromatin associated protein KTI12 8.2E-15 5-125 / 1-121
PF07931.11 Chloramphenicol phosphotransferase-like protein 6.8E-14 5-33 / 1-29
PF01591.17 6-phosphofructo-2-kinase 1E-13 3-36 / 7-40
PF01745.15 Isopentenyl transferase 3.8E-13 5-40 / 1-36
PF00406.21 Adenylate kinase 5.3E-13 10-126 / 1-123
PF01583.19 Adenylylsulphate kinase 7E-13 5-125 / 2-121
PF13238.5 AAA domain 1.1E-12 8-34 / 1-27
PF08303.10 tRNA ligase kinase domain 1.7E-12 7-40 / 1-35
PF01712.18 Deoxynucleoside kinase 3.7E-12 8-35 / 1-28
PF13207.5 AAA domain 5.4E-12 11-41 / 1-31
PF13189.5 Cytidylate kinase-like family 7.4E-12 7-39 / 1-33
PF03668.14 P-loop ATPase protein family 1.2E-11 5-36 / 1-31
PF00625.20 Guanylate kinase 1.4E-11 4-30 / 1-27
PF01121.19 Dephospho-CoA kinase 8.7E-11 6-41 / 1-36
PF03976.13 Polyphosphate kinase 2 (PPK2) 1.5E-10 3-31 / 26-54
PF02223.16 Thymidylate kinase 1.6E-10 10-34 / 1-25
PF01202.21 Shikimate kinase 2E-10 14-43 / 1-30
PF02224.17 Cytidylate kinase 4.6E-10 8-40 / 1-33
PF13521.5 AAA domain 9.9E-10 7-34 / 1-28
PF00485.17 Phosphoribulokinase / Uridine kinase family 7E-09 7-30 / 1-24
PF04275.13 Phosphomevalonate kinase 1.3E-08 10-40 / 1-34
PF06431.10 Polyomavirus large T antigen C-terminus 8.3E-08 4-32 / 154-182
PF07475.11 HPr Serine kinase C-terminal domain 9.8E-08 4-38 / 13-46
PF03215.14 Rad17 cell cycle checkpoint protein 1.1E-07 4-33 / 44-73
PF00910.21 RNA helicase 1.5E-07 8-30 / 1-23
PF13173.5 AAA domain 1.6E-07 5-28 / 2-25
PF10649.8 Protein of unknown function (DUF2478) 1.9E-07 9-30 / 2-23
PF05272.10 Virulence-associated protein E 2E-07 4-29 / 58-83
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 2.7E-07 4-29 / 3-28
PF03266.14 NTPase 2.8E-07 8-29 / 2-23
PF05729.11 NACHT domain 3.3E-07 7-29 / 2-24
PF17213.2 Hydin Adenylate kinase-like domain 3.4E-07 7-43 / 1-37
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 4.3E-07 5-31 / 32-58
PF00004.28 ATPase family associated with various cellular activities (AAA) 4.3E-07 8-30 / 1-23
PF00519.16 Papillomavirus helicase 4.9E-07 4-33 / 261-290
PF00308.17 Bacterial dnaA protein 5.3E-07 5-29 / 33-57
PF12780.6 P-loop containing dynein motor region D4 6.1E-07 5-34 / 31-60
PF01637.17 ATPase domain predominantly from Archaea 6.3E-07 4-29 / 19-44
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 6.5E-07 4-30 / 44-70
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 6.7E-07 8-30 / 1-23
PF00265.17 Thymidine kinase 7.4E-07 6-29 / 2-25
PF13401.5 AAA domain 7.8E-07 4-29 / 4-29
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8.2E-07 7-29 / 2-24
PF07693.13 KAP family P-loop domain 8.6E-07 3-29 / 29-55
PF12775.6 P-loop containing dynein motor region D3 9E-07 4-30 / 32-58
PF09848.8 Uncharacterized conserved protein (DUF2075) 8.9E-07 6-29 / 2-25
PF07728.13 AAA domain (dynein-related subfamily) 9.3E-07 8-29 / 2-23
PF13177.5 DNA polymerase III, delta subunit 8.7E-07 5-29 / 19-43
PF03969.15 AFG1-like ATPase 9.1E-07 4-30 / 66-92
PF05621.10 Bacterial TniB protein 9.5E-07 6-29 / 39-62
PF05673.12 Protein of unknown function (DUF815) 1E-06 5-29 / 54-78
PF01443.17 Viral (Superfamily 1) RNA helicase 1E-06 8-28 / 1-20
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 1.1E-06 4-29 / 13-38
PF04851.14 Type III restriction enzyme, res subunit 1.2E-06 4-29 / 22-47
PF00158.25 Sigma-54 interaction domain 1.2E-06 4-29 / 21-46
PF09820.8 Predicted AAA-ATPase 1.2E-06 5-29 / 31-55
PF04665.11 Poxvirus A32 protein 1.2E-06 4-29 / 12-37
PF05707.11 Zonular occludens toxin (Zot) 1.6E-06 7-25 / 2-20
PF07726.10 ATPase family associated with various cellular activities (AAA) 1.6E-06 8-30 / 2-24
PF01695.16 IstB-like ATP binding protein 1.6E-06 4-29 / 47-72
PF14516.5 AAA-like domain 1.8E-06 4-29 / 29-54
PF13191.5 AAA ATPase domain 2.1E-06 5-29 / 24-48
PF14532.5 Sigma-54 interaction domain 2.2E-06 5-29 / 21-45
PF01078.20 Magnesium chelatase, subunit ChlI 2.2E-06 5-29 / 22-46
PF00493.22 MCM2/3/5 family 2.3E-06 5-30 / 57-82
PF00448.21 SRP54-type protein, GTPase domain 3E-06 6-29 / 2-25
PF13479.5 AAA domain 3E-06 5-27 / 2-24
PF00931.21 NB-ARC domain 3.3E-06 4-29 / 19-44
PF01057.16 Parvovirus non-structural protein NS1 3.2E-06 4-30 / 117-143
PF02562.15 PhoH-like protein 3.3E-06 5-27 / 19-41
PF10443.8 RNA12 protein 3.6E-06 4-29 / 16-42
PF00693.17 Thymidine kinase from herpesvirus 3.7E-06 12-30 / 1-19
PF01926.22 50S ribosome-binding GTPase 4E-06 8-28 / 2-22
PF03796.14 DnaB-like helicase C terminal domain 4E-06 4-29 / 18-43
PF13481.5 AAA domain 4.1E-06 5-29 / 28-52
PF10923.7 P-loop Domain of unknown function (DUF2791) 4.3E-06 4-29 / 48-73
PF13654.5 AAA domain 4.6E-06 4-30 / 23-49
PF07724.13 AAA domain (Cdc48 subfamily) 4.8E-06 5-29 / 3-27
PF06745.12 KaiC 5E-06 4-29 / 18-43
PF02492.18 CobW/HypB/UreG, nucleotide-binding domain 5.3E-06 6-26 / 1-21
PF00437.19 Type II/IV secretion system protein 5.5E-06 5-29 / 130-154
PF06309.10 Torsin 5.7E-06 5-30 / 52-77
PF11602.7 ATPase P4 of dsRNA bacteriophage phi-12 6.2E-06 4-29 / 121-146
PF09439.9 Signal recognition particle receptor beta subunit 6.6E-06 5-28 / 3-26
PF13245.5 AAA domain 6.8E-06 4-29 / 10-35
PF07088.10 GvpD gas vesicle protein 0.0021 4-29 / 257-285
PF06068.12 TIP49 C-terminus 7.3E-06 4-30 / 49-75
PF13304.5 AAA domain, putative AbiEii toxin, Type IV TA system 8.4E-06 7-25 / 1-19
PF13604.5 AAA domain 8.2E-06 8-28 / 19-40
PF08423.10 Rad51 9.1E-06 4-29 / 36-61
PF10236.8 Mitochondrial ribosomal death-associated protein 3 9.7E-06 4-29 / 23-48
PF13337.5 Putative ATP-dependent Lon protease 1.1E-05 4-29 / 205-230
PF13476.5 AAA domain 1.1E-05 5-29 / 20-44
PF00154.20 recA bacterial DNA recombination protein 1.1E-05 4-29 / 51-76
PF05970.13 PIF1-like helicase 1.1E-05 4-29 / 21-46
PF08298.10 PrkA AAA domain 1.2E-05 4-30 / 84-110
PF10662.8 Ethanolamine utilisation - propanediol utilisation 1.3E-05 6-27 / 2-23
PF01580.17 FtsK/SpoIIIE family 1.4E-05 4-28 / 37-61
PF07652.13 Flavivirus DEAD domain 1.5E-05 4-27 / 3-27
PF05127.13 Helicase 2.1E-05 9-29 / 1-21
PF03029.16 Conserved hypothetical ATP binding protein 2.3E-05 10-29 / 1-20
PF16575.4 mRNA cleavage and polyadenylation factor CLP1 P-loop 2.4E-05 12-29 / 1-18
PF00350.22 Dynamin family 2.8E-05 8-28 / 1-21
PF04670.11 Gtr1/RagA G protein conserved region 2.8E-05 8-28 / 2-22
PF00071.21 Ras family 3E-05 8-28 / 2-22
PF06048.10 Domain of unknown function (DUF927) 2.9E-05 4-31 / 187-214
PF13086.5 AAA domain 3.3E-05 8-29 / 19-40
PF00025.20 ADP-ribosylation factor family 3.4E-05 3-28 / 12-37
PF03308.15 ArgK protein 3.9E-05 4-29 / 28-53
PF04548.15 AIG1 family 4E-05 7-28 / 2-23
PF13166.5 AAA domain 4.2E-05 4-29 / 17-42
PF02421.17 Ferrous iron transport protein B 4.4E-05 8-28 / 2-22
PF16813.4 CRISPR-associated protein Csn2 subfamily St 4.4E-05 4-30 / 14-40
PF00488.20 MutS domain V 4.7E-05 8-29 / 1-22
PF01935.16 Domain of unknown function DUF87 4.8E-05 5-29 / 25-49
PF02456.14 Adenovirus IVa2 protein 5.4E-05 7-28 / 82-105
PF11111.7 Centromere protein M (CENP-M) 5.6E-05 4-28 / 14-38
PF03205.13 Molybdopterin guanine dinucleotide synthesis protein B 6.4E-05 7-29 / 1-23
PF00009.26 Elongation factor Tu GTP binding domain 6.3E-05 4-28 / 2-26
PF00735.17 Septin 7.8E-05 5-28 / 4-27
PF02367.16 Threonylcarbamoyl adenosine biosynthesis protein TsaE 8.4E-05 4-30 / 20-46
PF12631.6 MnmE helical domain 9E-05 5-28 / 94-117
PF04317.11 YcjX-like family, DUF463 9.3E-05 7-29 / 2-24
PF10412.8 Type IV secretion-system coupling protein DNA-binding domain 0.0001 5-28 / 15-38
PF13175.5 AAA ATPase domain 0.0001 7-29 / 24-46
PF02689.13 Helicase 0.0001 5-30 / 53-78
PF03193.15 RsgA GTPase 0.00012 6-28 / 107-129
PF02263.18 Guanylate-binding protein, N-terminal domain 0.00012 4-27 / 20-43
PF16260.4 Domain of unknown function (DUF4914) 0.00011 4-27 / 239-262
PF05049.12 Interferon-inducible GTPase (IIGP) 0.00012 4-27 / 34-57
PF00503.19 G-protein alpha subunit 0.00012 5-28 / 21-44
PF04310.11 MukB N-terminal 0.00013 5-28 / 26-49
PF00580.20 UvrD/REP helicase N-terminal domain 0.00013 5-28 / 13-36
PF12846.6 AAA-like domain 0.00014 4-28 / 20-44
PF07755.10 Domain of unknown function (DUF1611_C) P-loop domain 0.00016 3-29 / 8-35
PF01293.19 Phosphoenolpyruvate carboxykinase 0.00016 5-23 / 205-223
PF02606.13 Tetraacyldisaccharide-1-P 4'-kinase 0.00016 5-29 / 34-60
PF00142.17 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 0.00019 7-29 / 2-24
PF09818.8 Predicted ATPase of the ABC class 0.00019 4-26 / 247-268
PF09547.9 Stage IV sporulation protein A (spore_IV_A) 0.0002 4-29 / 16-41
PF08477.12 Ras of Complex, Roc, domain of DAPkinase 0.00022 8-27 / 2-21
PF05872.11 Bacterial protein of unknown function (DUF853) 0.00022 5-29 / 21-45
PF13500.5 AAA domain 0.00025 9-30 / 4-25
PF05783.10 Dynein light intermediate chain (DLIC) 0.00031 5-27 / 25-47
PF09140.10 ATPase MipZ 0.00037 7-29 / 3-25
PF13514.5 AAA domain 0.00044 4-28 / 25-49
PF04735.11 Baculovirus DNA helicase 0.00042 5-32 / 906-933
PF00063.20 Myosin head (motor domain) 0.00051 3-29 / 83-109
PF02374.14 Anion-transporting ATPase 0.00053 6-29 / 2-25
PF09807.8 Elongation complex protein 6 0.00073 4-28 / 17-40
PF00005.26 ABC transporter 0.00078 4-29 / 10-35
PF06564.11 Cellulose biosynthesis protein BcsQ 0.00078 6-29 / 2-26
PF07015.10 VirC1 protein 0.00083 7-29 / 4-26
PF11398.7 Protein of unknown function (DUF2813) 0.001 8-29 / 25-46
PF08283.10 Geminivirus rep protein central domain 0.001 3-20 / 88-105
PF00270.28 DEAD/DEAH box helicase 0.0011 5-26 / 14-35
PF10609.8 NUBPL iron-transfer P-loop NTPase 0.0012 5-29 / 3-28
PF02463.18 RecF/RecN/SMC N terminal domain 0.0014 6-30 / 25-49
PF04466.12 Phage terminase large subunit 0.0014 6-26 / 2-22
PF13614.5 AAA domain 0.002 6-29 / 3-26
PF02534.13 Type IV secretory system Conjugative DNA transfer 0.0021 6-22 / 44-60
PF13148.5 Protein of unknown function (DUF3987) 0.003 6-27 / 37-58
PF12128.7 Protein of unknown function (DUF3584) 0.0032 5-29 / 19-43
PF06144.12 DNA polymerase III, delta subunit 0.0032 8-29 / 1-22
PF07999.10 Retrotransposon hot spot protein 0.0032 5-22 / 126-143
PF01656.22 CobQ/CobB/MinD/ParA nucleotide binding domain 0.0035 8-29 / 2-23
PF02399.14 Origin of replication binding protein 0.0048 4-27 / 48-71
PF00821.17 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 0.0089 13-25 / 26-38

Annotations of the NCBI proteins of this PHROG


1:ZipA protein 1:cell division protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0009245 lipid A biosynthetic process
GO:0000155 phosphorelay sensor kinase activity
GO:0016491 oxidoreductase activity
GO:0004386 helicase activity
GO:0009291 unidirectional conjugation
GO:0031683 G-protein beta/gamma-subunit complex binding
GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
GO:0005525 GTP binding
GO:0004797 thymidine kinase activity
GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity
GO:0003697 single-stranded DNA binding
GO:0030261 chromosome condensation
GO:0006281 DNA repair
GO:0003723 RNA binding
GO:0006230 TMP biosynthetic process
GO:0016459 myosin complex
GO:0003887 DNA-directed DNA polymerase activity
GO:0019001 guanyl nucleotide binding
GO:0016787 hydrolase activity
GO:0009378 four-way junction helicase activity
GO:0019073 viral DNA genome packaging
GO:0043752 adenosylcobinamide kinase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0003972 RNA ligase (ATP) activity
GO:0004673 protein histidine kinase activity
GO:0000723 telomere maintenance
GO:0000166 nucleotide binding
GO:0006000 fructose metabolic process
GO:0002949 tRNA threonylcarbamoyladenosine modification
GO:0006355 regulation of transcription, DNA-templated
GO:0009029 tetraacyldisaccharide 4'-kinase activity
GO:0003676 nucleic acid binding
GO:0051188 cofactor biosynthetic process
GO:0007059 chromosome segregation
GO:0006139 nucleobase-containing compound metabolic process
GO:0003724 RNA helicase activity
GO:0016020 membrane
GO:0019072 viral genome packaging
GO:0009236 cobalamin biosynthetic process
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0000160 phosphorelay signal transduction system
GO:0043531 ADP binding
GO:0016887 ATPase activity
GO:0033588 Elongator holoenzyme complex
GO:0006270 DNA replication initiation
GO:0007186 G-protein coupled receptor signaling pathway
GO:0009058 biosynthetic process
GO:0004672 protein kinase activity
GO:0043934 sporulation
GO:0004611 phosphoenolpyruvate carboxykinase activity
GO:0009360 DNA polymerase III complex
GO:0004631 phosphomevalonate kinase activity
GO:0008026 ATP-dependent helicase activity
GO:0055114 oxidation-reduction process
GO:0019079 viral genome replication
GO:0009295 nucleoid
GO:0006109 regulation of carbohydrate metabolic process
GO:0006298 mismatch repair
GO:0004003 ATP-dependent DNA helicase activity
GO:0016301 kinase activity
GO:0008152 metabolic process
GO:0006094 gluconeogenesis
GO:0005524 ATP binding
GO:0003924 GTPase activity
GO:0030983 mismatched DNA binding
GO:0003688 DNA replication origin binding
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0003873 6-phosphofructo-2-kinase activity
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0006260 DNA replication
GO:0003678 DNA helicase activity
GO:0004127 cytidylate kinase activity
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0006695 cholesterol biosynthetic process
GO:0004161 dimethylallyltranstransferase activity
GO:0016740 transferase activity
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0005737 cytoplasm
GO:0015937 coenzyme A biosynthetic process
GO:0002098 tRNA wobble uridine modification
GO:0008134 transcription factor binding
GO:0006576 cellular biogenic amine metabolic process
GO:0003774 motor activity
GO:0004140 dephospho-CoA kinase activity

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