phrog_3557 is made of 40 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
148.57 172 148


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p437537 no NCBI prot ID no annotation VI_09606 Gammaproteobacteria_gi_433147199 Viruses.
p437818 no NCBI prot ID no annotation VI_09578 Gammaproteobacteria_gi_433085530 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p437624 no NCBI prot ID no annotation VI_09550 Gammaproteobacteria_gi_433026590 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p436895 no NCBI prot ID no annotation VI_08875 Gammaproteobacteria_gi_420768422_170_10179 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p438577 no NCBI prot ID no annotation VI_08880 Gammaproteobacteria_gi_420773455 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p438589 no NCBI prot ID no annotation VI_08871 Gammaproteobacteria_gi_420763236 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p437876 no NCBI prot ID no annotation VI_01803 Gammaproteobacteria_gi_545298889 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p437525 no NCBI prot ID no annotation VI_01650 Gammaproteobacteria_gi_545251915 Viruses.
p438556 no NCBI prot ID no annotation VI_06739 Gammaproteobacteria_gi_484017241 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p438601 no NCBI prot ID no annotation VI_06777 Gammaproteobacteria_gi_484221647 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p438716 no NCBI prot ID no annotation VI_09552 Gammaproteobacteria_gi_433031329 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p439891 no NCBI prot ID no annotation VI_09646 Gammaproteobacteria_gi_484118460_122301_130046 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p437637 no NCBI prot ID no annotation VI_01375 Gammaproteobacteria_gi_545159081 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p438970 no NCBI prot ID no annotation VI_08792 Gammaproteobacteria_gi_420632727_23139_31581 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p438473 no NCBI prot ID no annotation VI_09505 Gammaproteobacteria_gi_489044889 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p438011 no NCBI prot ID no annotation VI_01706 Gammaproteobacteria_gi_545270999 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae.
p436797 no NCBI prot ID no annotation VI_08862 Gammaproteobacteria_gi_420746582_19374_29392 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p437412 no NCBI prot ID no annotation VI_09644 Gammaproteobacteria_gi_433215478 Viruses.
p437501 no NCBI prot ID no annotation VI_08963 Gammaproteobacteria_gi_452724810 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p438338 no NCBI prot ID no annotation VI_09588 Gammaproteobacteria_gi_433104101 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p441890 no NCBI prot ID no annotation VI_02380 Gammaproteobacteria_gi_476381554 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p437489 no NCBI prot ID no annotation VI_09871 Gammaproteobacteria_gi_506937596 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae.
p436882 no NCBI prot ID no annotation VI_06394 Gammaproteobacteria_gi_116177078_7188_17197 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p437902 no NCBI prot ID no annotation VI_02818 Gammaproteobacteria_gi_476381473_1296873_1306094 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Inovirus.
p416345 no NCBI prot ID no annotation VI_11324 Gammaproteobacteria_gi_511012307_21261_33530 Viruses.
p441869 no NCBI prot ID no annotation VI_10329 Gammaproteobacteria_gi_485828640 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Lineavirus; Escherichia virus I22.
p416467 no NCBI prot ID no annotation VI_11323 Gammaproteobacteria_gi_511012061_21297_33562 Viruses.
p416466 no NCBI prot ID no annotation VI_11323 Gammaproteobacteria_gi_511012061_21297_33562 Viruses.
p439922 no NCBI prot ID no annotation VI_10338 Gammaproteobacteria_gi_485831310_0_7731 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Lineavirus; Escherichia virus I22.
p441875 no NCBI prot ID no annotation VI_10329 Gammaproteobacteria_gi_485828640 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Lineavirus; Escherichia virus I22.
p416449 no NCBI prot ID no annotation VI_11320 Gammaproteobacteria_gi_510998707_21127_33392 Viruses.
p439916 no NCBI prot ID no annotation VI_10338 Gammaproteobacteria_gi_485831310_0_7731 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Lineavirus; Escherichia virus I22.
p439919 no NCBI prot ID no annotation VI_10338 Gammaproteobacteria_gi_485831310_0_7731 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Lineavirus; Escherichia virus I22.
p416346 no NCBI prot ID no annotation VI_11324 Gammaproteobacteria_gi_511012307_21261_33530 Viruses.
p439175 no NCBI prot ID no annotation VI_11321 Gammaproteobacteria_gi_510999106_0_8288 Viruses.
p439176 no NCBI prot ID no annotation VI_11321 Gammaproteobacteria_gi_510999106_0_8288 Viruses.
p404637 no NCBI prot ID no annotation VI_10975 Gammaproteobacteria_gi_487543881 Viruses.
p441872 no NCBI prot ID no annotation VI_10329 Gammaproteobacteria_gi_485828640 Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; Tubulavirales; Inoviridae; Lineavirus; Escherichia virus I22.
p416448 no NCBI prot ID no annotation VI_11320 Gammaproteobacteria_gi_510998707_21127_33392 Viruses.
NC_029107_p3 YP_009226507.1 transcriptional regulator NC_029107 Ralstonia phage RS138 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_4174 33 no annotation unknown function 15 2.93E-63 53.65
phrog_3557 40 transcriptional regulator transcription regulation 8 4.17E-32 22.5
phrog_12585 8 no annotation unknown function 8 0 1000
phrog_15841 6 no annotation unknown function 6 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_13326 no annotation unknown function 91.9 0.027 27-83 / 19-78
phrog_1337 DNA binding protein DNA, RNA and nucleotide metabolism 90.3 0.058 13-54 / 6-48
phrog_1373 transcriptional regulator transcription regulation 96.5 3.5E-05 27-71 / 46-90
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 94.8 0.002 27-73 / 25-72
phrog_147 transcriptional regulator transcription regulation 97.0 3.2E-06 15-79 / 4-71
phrog_1529 no annotation unknown function 94.0 0.0057 16-52 / 6-42
phrog_1702 transcriptional repressor transcription regulation 93.9 0.0063 27-73 / 29-77
phrog_18104 transcriptional regulator transcription regulation 91.5 0.034 24-60 / 12-48
phrog_2136 no annotation unknown function 91.3 0.037 14-66 / 29-83
phrog_2328 transcriptional repressor transcription regulation 97.0 3.6E-06 12-76 / 14-79
phrog_2439 transcriptional regulator transcription regulation 95.5 0.00064 15-75 / 8-69
phrog_2967 transcriptional regulator transcription regulation 97.4 5.1E-07 9-80 / 4-77
phrog_3037 transcriptional repressor transcription regulation 98.0 1E-08 30-121 / 32-119
phrog_35 transcriptional repressor transcription regulation 94.4 0.0033 18-64 / 5-52
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 96.7 1.3E-05 16-74 / 12-69
phrog_3949 transcriptional repressor transcription regulation 94.7 0.0025 27-72 / 30-74
phrog_3 transcriptional repressor transcription regulation 97.2 1.7E-06 16-74 / 6-65
phrog_4268 transcriptional repressor transcription regulation 95.3 0.00088 14-69 / 36-90
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.0 0.0057 17-75 / 11-68
phrog_4583 transcriptional repressor transcription regulation 96.3 6E-05 13-72 / 10-70
phrog_4779 transcriptional regulator transcription regulation 94.8 0.0021 15-50 / 3-39
phrog_4836 CII-like regulator transcription regulation 91.0 0.042 16-78 / 85-148
phrog_4 transcriptional repressor transcription regulation 96.6 2.1E-05 15-81 / 5-68
phrog_5414 HTH DNA binding protein DNA, RNA and nucleotide metabolism 91.8 0.028 27-57 / 22-52
phrog_5823 transcriptional regulator transcription regulation 92.9 0.014 14-80 / 5-73
phrog_6223 transcriptional repressor transcription regulation 94.8 0.0019 13-51 / 6-43
phrog_638 transcriptional regulator transcription regulation 95.0 0.0015 26-69 / 17-60
phrog_7241 transcriptional regulator transcription regulation 95.2 0.001 12-73 / 65-122
phrog_7306 no annotation unknown function 98.7 1.6E-11 9-82 / 6-79
phrog_8038 no annotation unknown function 93.4 0.01 23-51 / 11-39
phrog_803 host nuclease inhibitor moron, auxiliary metabolic gene and host takeover 92.5 0.019 23-49 / 16-42
phrog_8 transcriptional regulator transcription regulation 98.0 1.2E-08 15-78 / 3-65
phrog_9103 transcriptional repressor transcription regulation 95.3 0.00092 26-74 / 21-69
phrog_9710 no annotation unknown function 92.4 0.021 25-79 / 26-82

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 3.2E-08 19-80 / 8-76
PF13744.5 Helix-turn-helix domain 6.7E-08 18-80 / 15-79
PF14590.5 Domain of unknown function (DUF4447) 2.4E-07 20-82 / 6-72
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 3E-07 26-82 / 3-60
PF04645.11 Protein of unknown function, DUF603 4.8E-07 17-80 / 3-67
PF01381.21 Helix-turn-helix 6.7E-07 29-78 / 4-54
PF05339.10 Protein of unknown function (DUF739) 8.8E-07 24-79 / 6-62
PF13413.5 Helix-turn-helix domain 1.1E-06 29-77 / 4-59
PF12844.6 Helix-turn-helix domain 2.1E-06 28-81 / 6-60
PF13560.5 Helix-turn-helix domain 4.4E-06 23-78 / 3-62
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 4.8E-06 34-82 / 9-57
PF08667.9 BetR domain 5E-06 21-82 / 5-71
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 5E-06 22-80 / 70-128
PF05269.10 Bacteriophage CII protein 5.3E-06 27-82 / 16-70
PF13443.5 Cro/C1-type HTH DNA-binding domain 2.1E-05 35-81 / 13-61
PF08965.9 Domain of unknown function (DUF1870) 2.2E-05 23-72 / 3-55
PF13693.5 Winged helix-turn-helix DNA-binding 8.8E-05 25-82 / 6-61
PF12116.7 Stage III sporulation protein D 0.00015 33-75 / 18-62
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.00018 24-72 / 116-165
PF00157.16 Pou domain - N-terminal to homeobox domain 0.00021 21-73 / 7-64
PF00356.20 Bacterial regulatory proteins, lacI family 0.00024 35-69 / 1-35
PF14549.5 DNA-binding transcriptional regulator Cro 0.00026 35-79 / 11-52
PF02376.14 CUT domain 0.00059 21-82 / 7-68
PF10654.8 Protein of unknown function (DUF2481) 0.0011 32-58 / 78-105

Annotations of the NCBI proteins of this PHROG


1:transcriptional regulator

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0043565 sequence-specific DNA binding
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0003700 DNA binding transcription factor activity
GO:0045893 positive regulation of transcription, DNA-templated

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