phrog_3638 is made of 39 protein sequences and is annotated as "CII-like transcriptional activator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
73.41 93 73


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p61476 no NCBI prot ID no annotation VI_02766 Gammaproteobacteria_gi_476380859_4002074_4053649 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p131498 no NCBI prot ID no annotation VI_08420 Gammaproteobacteria_gi_419989780_1155_43537 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p92565 no NCBI prot ID no annotation VI_12086 Gammaproteobacteria_gi_421913615_10310_56262 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p132406 no NCBI prot ID no annotation VI_08446 Gammaproteobacteria_gi_420018216_1278_43657 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p131262 no NCBI prot ID no annotation VI_08415 Gammaproteobacteria_gi_419983728_1227_43609 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p132191 no NCBI prot ID no annotation VI_08435 Gammaproteobacteria_gi_420007522_217577_259957 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p131748 no NCBI prot ID no annotation VI_08405 Gammaproteobacteria_gi_419973158_1165_43547 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p79861 no NCBI prot ID no annotation VI_03502 Gammaproteobacteria_gi_481847813_2203371_2251211 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p131689 no NCBI prot ID no annotation VI_08441 Gammaproteobacteria_gi_420013131_1262_43644 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p131439 no NCBI prot ID no annotation VI_08425 Gammaproteobacteria_gi_419995659_1251_43633 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p191522 no NCBI prot ID no annotation VI_12088 Gammaproteobacteria_gi_421915755_10236_47317 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p342225 no NCBI prot ID no annotation VI_09442 Gammaproteobacteria_gi_490363435_0_20971 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p131925 no NCBI prot ID no annotation VI_08457 Gammaproteobacteria_gi_420030072_1256_43638 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KY271400_p15 ARB15765.1 CII protein KY271400 Klebsiella phage 6 LV-2017 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae.
p131807 no NCBI prot ID no annotation VI_08451 Gammaproteobacteria_gi_420024314_1211_43593 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p132466 no NCBI prot ID no annotation VI_08483 Gammaproteobacteria_gi_420058116_1051_43430 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p361950 no NCBI prot ID no annotation VI_09160 Gammaproteobacteria_gi_483305691 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p132043 no NCBI prot ID no annotation VI_08410 Gammaproteobacteria_gi_419978343_1257_43639 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
KY271396_p38 ARQ94721.1 cII protein KY271396 Klebsiella phage 2 LV-2017 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p108360 no NCBI prot ID no annotation VI_03320 Gammaproteobacteria_gi_556493183_273839_318621 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p118404 no NCBI prot ID no annotation VI_08498 Gammaproteobacteria_gi_420079881_1511_45160 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p132286 no NCBI prot ID no annotation VI_08430 Gammaproteobacteria_gi_420000569_1142_43522 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p132166 no NCBI prot ID no annotation VI_08478 Gammaproteobacteria_gi_420053273_1200_43581 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p119295 no NCBI prot ID no annotation VI_08503 Gammaproteobacteria_gi_420083990_1592_45172 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p86915 no NCBI prot ID no annotation VI_02716 Gammaproteobacteria_gi_425079304_1056216_1103078 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p132526 no NCBI prot ID no annotation VI_08488 Gammaproteobacteria_gi_420064403_1230_43608 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p434353 no NCBI prot ID no annotation VI_09651 Gammaproteobacteria_gi_472291012 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p131285 no NCBI prot ID no annotation VI_09649 Gammaproteobacteria_gi_472285897_350747_393129 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p189744 no NCBI prot ID no annotation VI_11341 Gammaproteobacteria_gi_544772957 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p85803 no NCBI prot ID no annotation VI_03296 Gammaproteobacteria_gi_556403725_2651056_2698189 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p131380 no NCBI prot ID no annotation VI_08472 Gammaproteobacteria_gi_420047569_1161_43543 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p101303 no NCBI prot ID no annotation VI_03004 Gammaproteobacteria_gi_530627845_2989291_3034242 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p131948 no NCBI prot ID no annotation VI_09782 Gammaproteobacteria_gi_472298405_207854_250236 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p132346 no NCBI prot ID no annotation VI_08462 Gammaproteobacteria_gi_420035178_1221_43601 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p131830 no NCBI prot ID no annotation VI_08493 Gammaproteobacteria_gi_420070280_171969_214351 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p119587 no NCBI prot ID no annotation VI_12062 Gammaproteobacteria_gi_428151337_10236_53780 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p132103 no NCBI prot ID no annotation VI_08467 Gammaproteobacteria_gi_420041508_1155_43536 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p52102 no NCBI prot ID no annotation VI_11819 Gammaproteobacteria_gi_550711952_1498003_1553973 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p321071 no NCBI prot ID no annotation VI_07251 Gammaproteobacteria_gi_417595700 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_35 1577 transcriptional repressor transcription regulation 37 2.86E-83 73.67
phrog_1913 80 tail protein tail 27 2.07E-95 85.81
phrog_678 208 replication initiation O-like DNA, RNA and nucleotide metabolism 5 3.59E-14 4.57

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11423 no annotation unknown function 91.1 0.041 10-53 / 9-52
phrog_1558 no annotation unknown function 94.7 0.0023 24-69 / 116-157
phrog_1702 transcriptional repressor transcription regulation 92.2 0.023 28-59 / 30-64
phrog_17493 no annotation unknown function 91.4 0.034 28-54 / 54-81
phrog_191 CII-like transcriptional activator transcription regulation 99.1 2.8E-14 5-50 / 3-52
phrog_19579 transcriptional regulator transcription regulation 92.2 0.023 22-46 / 11-36
phrog_2538 terminase small subunit head and packaging 95.3 0.00081 29-54 / 23-46
phrog_309 terminase small subunit head and packaging 92.8 0.016 29-58 / 28-56
phrog_3218 terminase small subunit head and packaging 90.1 0.061 28-46 / 36-54
phrog_35 transcriptional repressor transcription regulation 93.4 0.0093 25-58 / 12-47
phrog_36 transcriptional regulator transcription regulation 91.5 0.034 25-57 / 105-137
phrog_3949 transcriptional repressor transcription regulation 95.9 0.00022 16-59 / 17-62
phrog_3 transcriptional repressor transcription regulation 90.5 0.052 26-54 / 17-45
phrog_4044 terminase small subunit head and packaging 93.8 0.007 29-48 / 34-53
phrog_409 transcriptional regulator transcription regulation 96.3 6.7E-05 23-53 / 7-37
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 92.5 0.019 26-47 / 21-42
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.0 0.014 29-47 / 22-40
phrog_57 terminase small subunit head and packaging 90.1 0.062 26-52 / 3-29
phrog_6223 transcriptional repressor transcription regulation 93.9 0.0061 28-60 / 20-52
phrog_638 transcriptional regulator transcription regulation 91.1 0.041 29-49 / 20-40
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 91.3 0.037 25-47 / 66-90
phrog_66 excisionase and transcriptional regulator integration and excision 95.9 0.00025 25-51 / 9-36
phrog_725 CII-like regulator transcription regulation 98.3 7.7E-10 5-61 / 5-64
phrog_7344 terminase small subunit head and packaging 95.0 0.0014 26-48 / 27-49
phrog_756 DNA binding protein DNA, RNA and nucleotide metabolism 91.3 0.037 26-48 / 20-42
phrog_8008 DNA binding protein DNA, RNA and nucleotide metabolism 93.5 0.0092 23-53 / 11-42
phrog_8 transcriptional regulator transcription regulation 94.1 0.0047 25-54 / 14-42
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 93.6 0.0078 15-54 / 8-49

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 2.2E-07 21-67 / 19-75
PF07638.10 ECF sigma factor 3E-07 8-54 / 132-178
PF03333.12 Adhesin biosynthesis transcription regulatory protein 6.4E-07 8-54 / 38-84
PF13413.5 Helix-turn-helix domain 8.8E-07 23-64 / 7-58
PF01381.21 Helix-turn-helix 9.5E-07 23-64 / 7-52
PF10654.8 Protein of unknown function (DUF2481) 1.3E-06 23-53 / 78-108
PF05339.10 Protein of unknown function (DUF739) 2.9E-06 23-69 / 14-64
PF05331.10 Protein of unknown function (DUF742) 3.7E-06 8-48 / 37-76
PF06530.11 Phage antitermination protein Q 3.8E-06 11-59 / 65-113
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 7.8E-06 8-55 / 16-63
PF12759.6 InsA C-terminal domain 1.1E-05 11-47 / 7-43
PF04545.15 Sigma-70, region 4 1.4E-05 9-48 / 4-47
PF07374.10 Protein of unknown function (DUF1492) 1.6E-05 6-48 / 51-94
PF13744.5 Helix-turn-helix domain 1.7E-05 24-65 / 30-76
PF07750.10 GcrA cell cycle regulator 1.6E-05 12-48 / 5-42
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 1.7E-05 23-48 / 11-36
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 1.9E-05 25-67 / 11-57
PF08281.11 Sigma-70, region 4 2.3E-05 7-48 / 8-49
PF07141.10 Putative bacteriophage terminase small subunit 2.8E-05 17-48 / 23-54
PF00292.17 'Paired box' domain 3E-05 9-48 / 17-56
PF16509.4 TrfB plasmid transcriptional repressor 3.2E-05 7-48 / 13-54
PF04552.12 Sigma-54, DNA binding domain 4E-05 22-48 / 45-71
PF16264.4 SatD family (SatD) 4.4E-05 7-48 / 148-194
PF12844.6 Helix-turn-helix domain 4.6E-05 24-65 / 11-56
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 5.4E-05 24-49 / 18-43
PF02001.15 Protein of unknown function DUF134 6.2E-05 8-53 / 30-75
PF08822.10 Protein of unknown function (DUF1804) 6.4E-05 12-48 / 5-42
PF13443.5 Cro/C1-type HTH DNA-binding domain 6.4E-05 24-67 / 9-59
PF01710.15 Transposase 6.5E-05 13-48 / 6-41
PF02796.14 Helix-turn-helix domain of resolvase 8.4E-05 23-47 / 19-43
PF09607.9 Brinker DNA-binding domain 8.6E-05 11-48 / 7-48
PF08535.9 KorB domain 8.9E-05 24-48 / 2-26
PF14590.5 Domain of unknown function (DUF4447) 8.9E-05 24-48 / 19-43
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 9.6E-05 20-48 / 121-149
PF14549.5 DNA-binding transcriptional regulator Cro 0.0001 24-65 / 9-50
PF13011.5 leucine-zipper of insertion element IS481 0.00011 23-48 / 22-47
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.00013 24-66 / 81-126
PF04218.12 CENP-B N-terminal DNA-binding domain 0.00014 25-48 / 23-46
PF13936.5 Helix-turn-helix domain 0.00015 22-46 / 17-41
PF10668.8 Phage terminase small subunit 0.00017 25-48 / 22-45
PF05269.10 Bacteriophage CII protein 0.00018 23-64 / 21-64
PF00356.20 Bacterial regulatory proteins, lacI family 0.00018 27-48 / 1-22
PF12824.6 Mitochondrial ribosomal protein subunit L20 0.00018 10-49 / 89-131
PF06322.10 Phage NinH protein 0.00019 24-48 / 15-39
PF13693.5 Winged helix-turn-helix DNA-binding 0.0002 24-64 / 14-55
PF13560.5 Helix-turn-helix domain 0.00021 23-63 / 12-57
PF08765.10 Mor transcription activator family 0.00027 24-48 / 71-95
PF05344.10 Domain of Unknown Function (DUF746) 0.00028 23-48 / 10-35
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.00037 23-47 / 25-48
PF12116.7 Stage III sporulation protein D 0.00035 24-48 / 18-42
PF05225.15 helix-turn-helix, Psq domain 0.00041 23-48 / 14-40
PF04936.11 Protein of unknown function (DUF658) 0.0004 25-48 / 14-37
PF00376.22 MerR family regulatory protein 0.00043 28-48 / 2-22
PF01371.18 Trp repressor protein 0.00046 21-48 / 44-71
PF07278.10 Protein of unknown function (DUF1441) 0.00055 26-48 / 2-24
PF11427.7 Tc3 transposase 0.00059 23-48 / 18-43
PF17443.1 Uncharacterized protein pXO2-72 0.00058 25-48 / 8-31
PF06806.11 Putative excisionase (DUF1233) 0.00059 26-48 / 10-32
PF04645.11 Protein of unknown function, DUF603 0.00062 24-48 / 18-46
PF10975.7 Protein of unknown function (DUF2802) 0.00061 16-45 / 34-63
PF02954.18 Bacterial regulatory protein, Fis family 0.00068 24-47 / 15-38
PF07506.10 RepB plasmid partitioning protein 0.00065 24-48 / 20-44
PF13411.5 MerR HTH family regulatory protein 0.00074 27-48 / 2-23
PF16677.4 DNA-packaging protein gp3 0.00082 24-48 / 28-52
PF11242.7 Protein of unknown function (DUF2774) 0.0009 22-48 / 11-37
PF07453.12 NUMOD1 domain 0.0009 26-45 / 20-39
PF08667.9 BetR domain 0.0009 24-65 / 17-66
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.00097 27-65 / 10-52
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.001 26-47 / 4-25
PF13591.5 MerR HTH family regulatory protein 0.0011 27-48 / 2-23
PF06413.10 Neugrin 0.0011 9-48 / 10-52
PF02042.14 RWP-RK domain 0.0013 23-48 / 10-35
PF07037.10 Putative transcription regulator (DUF1323) 0.0014 27-48 / 2-23
PF04967.11 HTH DNA binding domain 0.0016 26-48 / 24-46
PF13518.5 Helix-turn-helix domain 0.0017 24-48 / 10-34
PF13384.5 Homeodomain-like domain 0.0017 24-47 / 16-39
PF14493.5 Helix-turn-helix domain 0.0017 23-48 / 10-35
PF13404.5 AsnC-type helix-turn-helix domain 0.0022 24-47 / 16-39
PF13309.5 HTH domain 0.0022 26-46 / 42-62
PF09035.9 Excisionase from transposon Tn916 0.0023 24-46 / 14-36
PF01527.19 Transposase 0.0024 23-48 / 19-44
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.0028 27-47 / 53-73
PF13412.5 Winged helix-turn-helix DNA-binding 0.0031 25-48 / 17-40
PF09862.8 Protein of unknown function (DUF2089) 0.0034 11-48 / 35-72
PF10743.8 Regulatory phage protein cox 0.0034 24-48 / 10-34
PF12728.6 Helix-turn-helix domain 0.0037 26-48 / 2-25
PF13022.5 Helix-turn-helix of insertion element transposase 0.0039 25-48 / 25-48
PF01418.16 Helix-turn-helix domain, rpiR family 0.004 25-48 / 34-57
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.0042 24-48 / 22-46
PF07471.11 Phage DNA packaging protein Nu1 0.0043 26-48 / 3-25
PF15978.4 Tn7-like transposition protein D 0.0044 24-48 / 202-226
PF13556.5 PucR C-terminal helix-turn-helix domain 0.0045 24-48 / 11-35
PF06627.10 Protein of unknown function (DUF1153) 0.0046 25-48 / 46-69
PF08299.10 Bacterial dnaA protein helix-turn-helix 0.0047 23-46 / 42-66
PF06971.12 Putative DNA-binding protein N-terminus 0.0054 25-46 / 27-48
PF00196.18 Bacterial regulatory proteins, luxR family 0.0063 22-48 / 14-40
PF00325.19 Bacterial regulatory proteins, crp family 0.0064 27-47 / 4-24
PF00440.22 Bacterial regulatory proteins, tetR family 0.007 26-48 / 16-38
PF12964.6 Protein of unknown function (DUF3853) 0.0071 25-48 / 45-68
PF13551.5 Winged helix-turn helix 0.0084 24-48 / 10-34
PF09048.9 Cro 0.0088 24-48 / 12-36
PF04492.12 Bacteriophage replication protein O 0.0092 25-48 / 49-72

Annotations of the NCBI proteins of this PHROG


1:CII protein 1:cII protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0000150 recombinase activity
GO:0006313 transposition, DNA-mediated
GO:0003700 DNA binding transcription factor activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0006275 regulation of DNA replication
GO:0006260 DNA replication
GO:0005622 intracellular
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0016987 sigma factor activity
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0006270 DNA replication initiation
GO:0004803 transposase activity
GO:0043565 sequence-specific DNA binding
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0051775 response to redox state
GO:0006352 DNA-templated transcription, initiation
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0019069 viral capsid assembly

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