phrog_3646 is made of 39 protein sequences and is annotated as "6-phosphogluconate dehydrogenase"
Functional category: other


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
158.74 170 158


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KJ019042_p102 AIX17754.1 6-phosphogluconate dehydrogenase KJ019042 Synechococcus phage ACG-2014b Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Nereusvirus; Synechococcus virus ACG2014bSyn7803C61.
KJ019065_p94 AIX23077.1 6-phosphogluconate dehydrogenase KJ019065 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
NC_021530_p96 YP_008125632.1 hypothetical protein NC_021530 Synechococcus phage S-CAM8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019030_p97 AIX15146.1 6-phosphogluconate dehydrogenase KJ019030 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019027_p95 AIX14490.1 6-phosphogluconate dehydrogenase KJ019027 Synechococcus phage ACG-2014c Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019158_p94 AIX45437.1 6-phosphogluconate dehydrogenase KJ019158 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019041_p101 AIX17538.1 6-phosphogluconate dehydrogenase KJ019041 Synechococcus phage ACG-2014b Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Nereusvirus; Synechococcus virus ACG2014bSyn7803C61.
KJ019133_p103 AIX39186.1 6-phosphogluconate dehydrogenase KJ019133 Synechococcus phage ACG-2014b Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Nereusvirus; Synechococcus virus ACG2014bSyn7803C61.
KJ019084_p96 AIX27247.1 6-phosphogluconate dehydrogenase KJ019084 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019063_p94 AIX22647.1 6-phosphogluconate dehydrogenase KJ019063 Synechococcus phage ACG-2014c Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019039_p93 AIX17109.1 6-phosphogluconate dehydrogenase KJ019039 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019157_p97 AIX45229.1 6-phosphogluconate dehydrogenase KJ019157 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019026_p95 AIX14280.1 6-phosphogluconate dehydrogenase KJ019026 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
NC_027130_p104 YP_009140672.1 6-phosphogluconate dehydrogenase NC_027130 Synechococcus phage ACG-2014b Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Nereusvirus; Synechococcus virus ACG2014bSyn7803C61.
NC_019444_p96 YP_007001822.1 gnd 6PGDH NC_019444 Synechococcus phage ACG-2014c Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
NC_023584_p100 YP_009007957.1 hypothetical protein NC_023584 Synechococcus phage S-MbCM100 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; Synechococcus virus SMbCM100.
KJ019067_p94 AIX23573.1 6-phosphogluconate dehydrogenase KJ019067 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019132_p101 AIX38969.1 6-phosphogluconate dehydrogenase KJ019132 Synechococcus phage ACG-2014b Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Nereusvirus; Synechococcus virus ACG2014bSyn7803C61.
KJ019033_p93 AIX15790.1 6-phosphogluconate dehydrogenase KJ019033 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019122_p95 AIX36731.1 6-phosphogluconate dehydrogenase KJ019122 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019153_p95 AIX44307.1 6-phosphogluconate dehydrogenase KJ019153 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019135_p96 AIX39614.1 6-phosphogluconate dehydrogenase KJ019135 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019064_p94 AIX22862.1 6-phosphogluconate dehydrogenase KJ019064 Synechococcus phage ACG-2014c Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KU686203_p100 AOV60036.1 6-phosphogluconate dehydrogenase KU686203 Synechococcus phage S-CAM8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019128_p94 AIX38095.1 6-phosphogluconate dehydrogenase KJ019128 Synechococcus phage ACG-2014c Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019055_p96 AIX20776.1 6-phosphogluconate dehydrogenase KJ019055 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019163_p93 AIX46585.1 6-phosphogluconate dehydrogenase KJ019163 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019088_p95 AIX28231.1 6-phosphogluconate dehydrogenase KJ019088 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019076_p95 AIX25527.1 6-phosphogluconate dehydrogenase KJ019076 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KF156339_p95 AHB80730.1 hypothetical protein KF156339 Synechococcus phage S-MbCM25 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019138_p96 AIX40250.1 6-phosphogluconate dehydrogenase KJ019138 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019116_p94 AIX35435.1 6-phosphogluconate dehydrogenase KJ019116 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019038_p95 AIX16902.1 6-phosphogluconate dehydrogenase KJ019038 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
NC_020851_p59 YP_007674424.1 hypothetical protein NC_020851 Synechococcus phage S-SKS1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Llyrvirus; Synechococcus virus SSKS1.
KJ019068_p94 AIX23779.1 6-phosphogluconate dehydrogenase KJ019068 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019161_p105 AIX46160.1 6-phosphogluconate dehydrogenase KJ019161 Synechococcus phage ACG-2014b Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Nereusvirus; Synechococcus virus ACG2014bSyn7803C61.
KJ019154_p102 AIX44522.1 6-phosphogluconate dehydrogenase KJ019154 Synechococcus phage ACG-2014b Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Nereusvirus; Synechococcus virus ACG2014bSyn7803C61.
KJ019137_p97 AIX40041.1 6-phosphogluconate dehydrogenase KJ019137 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.
KJ019087_p94 AIX28023.1 6-phosphogluconate dehydrogenase KJ019087 Synechococcus phage ACG-2014a Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Acionnavirus; unclassified Acionnavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1201 125 no annotation unknown function 38 1.28E-131 122.01
phrog_2064 73 no annotation unknown function 23 7.27E-81 71.26
phrog_515 264 PetE plastocyanine other 15 3.20E-41 31.62

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1319 dehydrogenase other 100.0 5.9E-46 1-153 / 1-167
phrog_9148 UDP-glucose dehydrogenase other 95.0 0.0015 1-129 / 1-143

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01210.22 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4.8E-08 2-108 / 1-104
PF03721.13 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1.2E-07 1-33 / 1-33
PF07991.11 Acetohydroxy acid isomeroreductase, NADPH-binding domain 1.8E-07 1-105 / 5-93
PF13380.5 CoA binding domain 3.8E-07 1-128 / 1-105
PF02826.18 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 5.5E-07 1-126 / 34-142
PF01408.21 Oxidoreductase family, NAD-binding Rossmann fold 5.6E-07 1-32 / 1-35
PF16924.4 Dipicolinate synthase subunit A N-terminal domain 6.2E-07 2-32 / 1-31
PF10100.8 Staphylopine dehydrogenase 6.2E-07 1-34 / 1-35
PF00670.20 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 6.9E-07 1-108 / 24-111
PF01113.19 Dihydrodipicolinate reductase, N-terminus 9.5E-07 1-30 / 1-30
PF03446.14 NAD binding domain of 6-phosphogluconate dehydrogenase 9.7E-07 2-33 / 1-32
PF05221.16 S-adenosyl-L-homocysteine hydrolase 1.2E-06 1-120 / 262-362
PF10727.8 Rossmann-like domain 1.6E-06 3-108 / 1-93
PF03807.16 NADP oxidoreductase coenzyme F420-dependent 2.5E-06 2-32 / 1-35
PF02558.15 Ketopantoate reductase PanE/ApbA 3.5E-06 3-108 / 1-100
PF00056.22 lactate/malate dehydrogenase, NAD binding domain 5.4E-06 1-34 / 1-36
PF02737.17 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8.5E-06 2-33 / 1-32
PF02056.15 Family 4 glycosyl hydrolase 1.3E-05 2-33 / 1-38
PF01488.19 Shikimate / quinate 5-dehydrogenase 1.5E-05 1-33 / 13-46
PF00185.23 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 2.6E-05 1-33 / 3-36
PF03447.15 Homoserine dehydrogenase, NAD binding domain 2.9E-05 7-32 / 1-29
PF01262.20 Alanine dehydrogenase/PNT, C-terminal domain 3.8E-05 2-33 / 28-59
PF02254.17 TrkA-N domain 4.1E-05 3-32 / 1-32
PF02423.14 Ornithine cyclodeaminase/mu-crystallin family 4.2E-05 2-108 / 134-228
PF00208.20 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 5E-05 1-29 / 32-60
PF13241.5 Putative NAD(P)-binding 0.00012 1-32 / 10-41
PF02844.14 Phosphoribosylglycinamide synthetase, N domain 0.00024 1-32 / 1-34
PF02882.18 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 0.00027 1-32 / 37-69
PF01118.23 Semialdehyde dehydrogenase, NAD binding domain 0.0005 2-30 / 1-31
PF13478.5 XdhC Rossmann domain 0.0005 3-33 / 1-31
PF03435.17 Saccharopine dehydrogenase NADP binding domain 0.00059 3-32 / 1-34
PF02629.18 CoA binding domain 0.0015 1-27 / 4-30
PF00044.23 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 0.0019 1-29 / 1-30
PF05368.12 NmrA-like family 0.0025 3-32 / 1-31
PF00479.21 Glucose-6-phosphate dehydrogenase, NAD binding domain 0.0029 74-94 / 98-118
PF01266.23 FAD dependent oxidoreductase 0.0031 2-32 / 1-31
PF00389.29 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 0.0049 1-33 / 133-165
PF02571.13 Precorrin-6x reductase CbiJ/CobK 0.0051 2-32 / 1-30
PF02153.16 Prephenate dehydrogenase 0.0068 71-108 / 41-78
PF04321.16 RmlD substrate binding domain 0.007 1-31 / 1-32
PF06100.10 MCRA family 0.0075 1-32 / 2-37
PF01494.18 FAD binding domain 0.0092 2-32 / 3-33

Annotations of the NCBI proteins of this PHROG


34:6-phosphogluconate dehydrogenase 4:hypothetical protein 1:gnd 6PGDH

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K00033 PGD, gnd, gntZ : 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] ko00030 Pentose phosphate pathway
ko00480 Glutathione metabolism
ko01200 Carbon metabolism
67 39

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0008977 prephenate dehydrogenase (NAD+) activity
GO:0016994 precorrin-6A reductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016491 oxidoreductase activity
GO:0006571 tyrosine biosynthetic process
GO:0016597 amino acid binding
GO:0016743 carboxyl- or carbamoyltransferase activity
GO:0055114 oxidation-reduction process
GO:0048037 cofactor binding
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity
GO:0006631 fatty acid metabolic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0071949 FAD binding
GO:0008152 metabolic process
GO:0005975 carbohydrate metabolic process
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0006813 potassium ion transport
GO:0046168 glycerol-3-phosphate catabolic process
GO:0004637 phosphoribosylamine-glycine ligase activity
GO:0004665 prephenate dehydrogenase (NADP+) activity
GO:0008839 4-hydroxy-tetrahydrodipicolinate reductase
GO:0009113 purine nucleobase biosynthetic process
GO:0050661 NADP binding
GO:0006520 cellular amino acid metabolic process
GO:0009236 cobalamin biosynthetic process
GO:0004345 glucose-6-phosphate dehydrogenase activity
GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0006006 glucose metabolic process
GO:0050151 oleate hydratase activity
GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
GO:0051287 NAD binding

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