phrog_3676 is made of 39 protein sequences and is annotated as "thymidylate synthase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
355.38 608 350


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_024122_p37 YP_009030359.1 hypothetical protein NC_024122 Salmonella phage vB_SalM_SJ3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_027119_p108 YP_009140285.1 thymidylate synthetase NC_027119 Salmonella phage Det7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_027340_p41 YP_009147553.1 thymidylate synthase NC_027340 Erwinia phage phiEa2809 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae.
MG428991_p162 AUG88083.1 thymidylate synthase MG428991 Klebsiella phage May Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Klebsiella virus May.
NC_016570_p55 YP_004957758.1 putative thymidylate synthase NC_016570 Escherichia virus CBA120 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_019910_p115 YP_007236210.1 hypothetical protein NC_019910 Salmonella phage SKML-39 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Agtrevirus.
KY630163_p59 ARB06345.1 thymidylate synthase KY630163 Salmonella phage S8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
NC_019530_p47 YP_007008027.1 thymidylate synthase NC_019530 Salmonella phage Sh19 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_013693_p59 YP_003358546.1 putative thymidylate synthase NC_013693 Shigella phage Ag3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Agtrevirus.
NC_015296_p60 YP_004327431.1 Thymidylate synthase NC_015296 Salmonella phage ViI Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
NC_019452_p58 YP_007002698.1 putative thymidylate synthase NC_019452 Escherichia phage PhaxI Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
KX147096_p17 ANM47126.1 thymidylate synthase KX147096 Serratia phage vB_Sru_IME250 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Serratia virus IME250.
MG383452_p117 ATW66875.1 thymidylate synthase MG383452 Escherichia phage FEC14 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
NC_025452_p12 YP_009102852.1 thymidylate synthase family protein NC_025452 Dickeya phage RC-2014 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus.
NC_019925_p45 YP_007237367.1 putative thymidylate synthase NC_019925 Dickeya virus Limestone Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus.
KM209228_p43 AIM51438.1 thymidylate synthase family protein KM209228 Dickeya phage phiD3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; Dickeya virus Limestone.
KY942057_p42 ASD51428.1 putative thymidylate synthase KY942057 Dickeya phage XF4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
NC_022772_p147 YP_008771765.1 thymidylate synthase NC_022772 Salmonella phage Marshall Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
MG428992_p163 AUG88298.1 thymidylate synthase MG428992 Salmonella phage Mutine Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
MG266157_p43 ATW62048.1 putative thymidylate synthase MG266157 Dickeya phage PP35 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
KY942056_p42 ASD51229.1 putative thymidylate synthase KY942056 Dickeya phage JA15 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
NC_029042_p203 YP_009220947.1 thymidylate synthase NC_029042 Salmonella phage 38 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
MG973030_p45 AVO22888.1 thymidylate synthase MG973030 Erwinia phage vB_EamM-Bue1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
NC_031045_p96 YP_009283869.1 thymidylate synthase NC_031045 Salmonella phage GG32 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_022768_p146 YP_008770973.1 thymidylate synthase NC_022768 Salmonella phage Maynard Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
MG770379_p34 AUV59150.1 thymidylate synthase MG770379 Klebsiella virus vB_KpnM_KpS110 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Klebsiella virus KpS110.
NC_016073_p55 YP_004895226.1 thymidylate synthase NC_016073 Salmonella phage SFP10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
KY787213_p200 ARM70037.1 thymidylate synthase KY787213 Salmonella phage BSP101 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
KX171211_p104 ANT44563.1 thymidylate synthase KX171211 Salmonella phage vB_SenM-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
MG428990_p164 AUG87870.1 thymidylate synthase MG428990 Klebsiella phage Menlow Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Klebsiella virus Menlow.
NC_025446_p30 YP_009101426.1 thymidylate synthase NC_025446 Escherichia phage ECML-4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
NC_031128_p1 YP_009293249.1 thymidylate synthase NC_031128 Salmonella phage vB_SalM_PM10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_022343_p33 YP_008531984.1 putative thymidylate synthase NC_022343 Klebsiella phage 0507-KN2-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus.
MF001362_p55 ASZ77602.1 putative thymidylate synthase MF001362 Salmonella phage SP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
KY914485_p44 ARK07863.1 putative thymidylate synthase KY914485 Aeromonas phage phiA8-29 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
NC_013697_p229 YP_003359084.1 deoxyuridylate hydroxymethyltransferase NC_013697 Deftia phage phiW-14 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ionavirus; Delftia virus PhiW14.
NC_020083_p149 YP_007349128.1 putative thymidylate synthase NC_020083 Serratia phage phiMAM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae.
MF285619_p161 ASZ78927.1 thymidylate synthase MF285619 Serratia phage 2050H1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
MF668275_p41 ASZ73358.1 thymidylate synthase MF668275 Brevibacterium phage LuckyBarnes Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Luckybarnesvirus; Brevibacterium virus LuckyBarnes.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_139 687 deoxynucleoside monophosphate kinase other 37 3.18E-97 87.62
phrog_800 180 terminase small subunit head and packaging 36 6.29E-117 107.32

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_160 thymidylate synthase DNA, RNA and nucleotide metabolism 99.8 1.3E-24 30-236 / 21-229
phrog_5131 thymidylate synthase DNA, RNA and nucleotide metabolism 100.0 3.2E-52 1-236 / 1-225
phrog_5682 thymidylate synthase DNA, RNA and nucleotide metabolism 94.6 0.0027 193-236 / 3-46

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00303.18 Thymidylate synthase 7.3E-37 24-266 / 2-260
PF07659.10 Domain of Unknown Function (DUF1599) 2.8E-14 394-449 / 1-61

Annotations of the NCBI proteins of this PHROG


32:thymidylate synthase 2:thymidylate synthase family protein 2:hypothetical protein 1:deoxyuridylate hydroxymethyltransferase 1:thymidylate synthetase 1:Thymidylate synthase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K00560 thyA, TYMS : thymidylate synthase [EC:2.1.1.45] ko00240 Pyrimidine metabolism
ko00670 One carbon pool by folate
166 39

GO terms in Uniprot proteins similar to this PHROG

ID Definition
no GO term               

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