phrog_37093 is made of 2 protein sequences and is annotated as "transcriptional regulator"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
42 42 42


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_007458_p28 YP_338211.1 transcriptional regulator, putative NC_007458 Bacillus phage Gamma Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.
DQ289556_p28 ABC40480.1 putative phage repressor fragment DQ289556 Bacillus phage Gamma isolate d'Herelle Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Wbetavirus; unclassified Wbetavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
no colocalized PHROGS                                                                                          

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1373 transcriptional regulator transcription regulation 94.9 0.0017 6-36 / 32-62
phrog_2328 transcriptional repressor transcription regulation 93.5 0.0089 6-36 / 16-46
phrog_2967 transcriptional regulator transcription regulation 95.2 0.001 2-30 / 5-33
phrog_3 transcriptional repressor transcription regulation 95.5 0.00061 5-31 / 3-29
phrog_4779 transcriptional regulator transcription regulation 92.7 0.017 7-36 / 3-32
phrog_8 transcriptional regulator transcription regulation 95.9 0.00021 6-35 / 2-30

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 2E-11 4-42 / 9-47
PF04645.11 Protein of unknown function, DUF603 3.9E-09 4-41 / 6-46
PF13413.5 Helix-turn-helix domain 6.2E-09 12-41 / 3-32
PF14590.5 Domain of unknown function (DUF4447) 1.2E-08 6-41 / 8-43
PF10654.8 Protein of unknown function (DUF2481) 1.9E-08 16-41 / 78-103
PF01381.21 Helix-turn-helix 3.3E-08 13-41 / 4-32
PF08965.9 Domain of unknown function (DUF1870) 4.1E-08 8-41 / 4-39
PF05339.10 Protein of unknown function (DUF739) 5.8E-08 8-41 / 6-39
PF13744.5 Helix-turn-helix domain 5.9E-08 7-41 / 20-54
PF13560.5 Helix-turn-helix domain 1.9E-07 8-41 / 4-37
PF13443.5 Cro/C1-type HTH DNA-binding domain 2.3E-07 13-41 / 5-34
PF00157.16 Pou domain - N-terminal to homeobox domain 2.4E-07 5-41 / 7-49
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 3.4E-07 13-41 / 6-35
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 4E-07 9-41 / 73-105
PF12844.6 Helix-turn-helix domain 5.4E-07 12-41 / 6-35
PF08535.9 KorB domain 7.3E-07 17-41 / 2-26
PF12116.7 Stage III sporulation protein D 7.6E-07 15-41 / 16-42
PF00356.20 Bacterial regulatory proteins, lacI family 7.8E-07 21-41 / 2-22
PF08667.9 BetR domain 1E-06 4-41 / 4-45
PF05269.10 Bacteriophage CII protein 1.2E-06 12-41 / 17-46
PF13693.5 Winged helix-turn-helix DNA-binding 1.3E-06 10-41 / 7-38
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 1.4E-06 10-41 / 118-149
PF02376.14 CUT domain 2.2E-06 6-41 / 8-44
PF06322.10 Phage NinH protein 2.4E-06 11-40 / 9-38
PF02042.14 RWP-RK domain 3.3E-06 12-40 / 6-34
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 4.7E-06 20-39 / 10-29
PF12824.6 Mitochondrial ribosomal protein subunit L20 4.5E-06 10-41 / 97-130
PF06806.11 Putative excisionase (DUF1233) 4.9E-06 17-41 / 8-32
PF14549.5 DNA-binding transcriptional regulator Cro 6E-06 12-38 / 4-29
PF04552.12 Sigma-54, DNA binding domain 6.9E-06 16-41 / 46-71
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 7.3E-06 17-40 / 12-35
PF07278.10 Protein of unknown function (DUF1441) 9E-06 19-41 / 2-24
PF02954.18 Bacterial regulatory protein, Fis family 1E-05 15-40 / 13-38
PF00376.22 MerR family regulatory protein 1.1E-05 21-40 / 2-21
PF07506.10 RepB plasmid partitioning protein 1.8E-05 10-40 / 14-43
PF07141.10 Putative bacteriophage terminase small subunit 1.8E-05 16-40 / 29-53
PF17443.1 Uncharacterized protein pXO2-72 2.1E-05 17-39 / 7-29
PF04936.11 Protein of unknown function (DUF658) 0.0011 17-40 / 87-110
PF13591.5 MerR HTH family regulatory protein 3.3E-05 20-40 / 2-22
PF13411.5 MerR HTH family regulatory protein 3.9E-05 20-40 / 2-22
PF08765.10 Mor transcription activator family 3.9E-05 17-41 / 71-95
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 4.2E-05 19-40 / 4-25
PF09035.9 Excisionase from transposon Tn916 4.2E-05 15-39 / 12-36
PF07037.10 Putative transcription regulator (DUF1323) 4.6E-05 20-40 / 2-22
PF13309.5 HTH domain 5.6E-05 19-39 / 42-62
PF02319.19 E2F/DP family winged-helix DNA-binding domain 5.8E-05 17-40 / 22-45
PF07453.12 NUMOD1 domain 5.9E-05 19-38 / 20-39
PF13404.5 AsnC-type helix-turn-helix domain 7.1E-05 16-40 / 15-39
PF04218.12 CENP-B N-terminal DNA-binding domain 7.3E-05 17-40 / 22-45
PF08822.10 Protein of unknown function (DUF1804) 8.1E-05 16-40 / 17-41
PF12759.6 InsA C-terminal domain 8.7E-05 17-40 / 20-43
PF05225.15 helix-turn-helix, Psq domain 8.8E-05 15-40 / 13-39
PF00440.22 Bacterial regulatory proteins, tetR family 9.9E-05 19-40 / 16-37
PF05344.10 Domain of Unknown Function (DUF746) 0.0001 17-40 / 11-34
PF06413.10 Neugrin 9.7E-05 18-41 / 29-52
PF13011.5 leucine-zipper of insertion element IS481 0.00011 16-40 / 22-46
PF13412.5 Winged helix-turn-helix DNA-binding 0.00011 16-40 / 15-39
PF03333.12 Adhesin biosynthesis transcription regulatory protein 0.00012 17-40 / 54-77
PF10743.8 Regulatory phage protein cox 0.00013 17-40 / 10-33
PF16677.4 DNA-packaging protein gp3 0.00014 16-40 / 27-51
PF02796.14 Helix-turn-helix domain of resolvase 0.00015 17-40 / 20-43
PF07471.11 Phage DNA packaging protein Nu1 0.00016 19-40 / 3-24
PF09607.9 Brinker DNA-binding domain 0.00017 19-40 / 26-47
PF09048.9 Cro 0.00017 18-40 / 13-35
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 0.00018 17-40 / 18-41
PF15978.4 Tn7-like transposition protein D 0.00018 16-40 / 201-225
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.00018 20-40 / 53-73
PF12728.6 Helix-turn-helix domain 0.0002 20-39 / 3-23
PF06971.12 Putative DNA-binding protein N-terminus 0.0002 18-39 / 27-48
PF00292.17 'Paired box' domain 0.00023 16-40 / 31-55
PF10668.8 Phage terminase small subunit 0.00029 18-40 / 22-44
PF10975.7 Protein of unknown function (DUF2802) 0.0003 15-38 / 40-63
PF12964.6 Protein of unknown function (DUF3853) 0.00032 17-40 / 44-67
PF12793.6 Sugar transport-related sRNA regulator N-term 0.00035 15-40 / 15-40
PF01371.18 Trp repressor protein 0.00036 16-40 / 46-70
PF13171.5 Protein of unknown function (DUF4004) 0.00034 19-41 / 3-25
PF01710.15 Transposase 0.00039 17-40 / 17-40
PF01022.19 Bacterial regulatory protein, arsR family 0.0004 17-40 / 15-38
PF07638.10 ECF sigma factor 0.00043 16-39 / 147-170
PF08222.10 CodY helix-turn-helix domain 0.0005 19-39 / 5-25
PF09012.9 FeoC like transcriptional regulator 0.00051 16-39 / 12-35
PF13936.5 Helix-turn-helix domain 0.00056 16-40 / 18-42
PF13022.5 Helix-turn-helix of insertion element transposase 0.00055 18-40 / 25-47
PF14493.5 Helix-turn-helix domain 0.00056 16-39 / 10-33
PF05043.12 Mga helix-turn-helix domain 0.0006 14-40 / 26-52
PF00325.19 Bacterial regulatory proteins, crp family 0.00068 21-38 / 5-22
PF16221.4 winged helix-turn-helix 0.00065 18-40 / 46-68
PF08281.11 Sigma-70, region 4 0.00077 16-39 / 24-47
PF11242.7 Protein of unknown function (DUF2774) 0.00075 16-39 / 12-35
PF04545.15 Sigma-70, region 4 0.00076 17-39 / 23-45
PF04492.12 Bacteriophage replication protein O 0.00079 18-40 / 49-71
PF05331.10 Protein of unknown function (DUF742) 0.00089 17-39 / 52-74
PF06892.10 Phage regulatory protein CII (CP76) 0.00092 20-41 / 21-42
PF04967.11 HTH DNA binding domain 0.00099 19-40 / 24-45
PF16509.4 TrfB plasmid transcriptional repressor 0.0012 17-39 / 30-52
PF13542.5 Helix-turn-helix domain of transposase family ISL3 0.0012 20-40 / 28-48
PF13556.5 PucR C-terminal helix-turn-helix domain 0.0013 18-40 / 12-34
PF09904.8 Winged helix-turn helix 0.0013 16-40 / 19-43
PF13518.5 Helix-turn-helix domain 0.0013 17-39 / 10-32
PF09182.9 Bacterial purine repressor, N-terminal 0.0013 16-39 / 18-41
PF01527.19 Transposase 0.0014 16-39 / 19-42
PF11427.7 Tc3 transposase 0.0015 17-39 / 19-41
PF06627.10 Protein of unknown function (DUF1153) 0.0015 17-40 / 45-68
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.0016 16-39 / 25-48
PF14056.5 Domain of unknown function (DUF4250) 0.0015 18-39 / 19-40
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.0016 16-40 / 20-44
PF02082.19 Transcriptional regulator 0.0019 19-39 / 25-45
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.0019 16-40 / 22-46
PF13601.5 Winged helix DNA-binding domain 0.0021 17-39 / 13-35
PF16264.4 SatD family (SatD) 0.002 17-40 / 170-193
PF01047.21 MarR family 0.0022 17-39 / 16-38
PF11994.7 Protein of unknown function (DUF3489) 0.002 10-40 / 13-43
PF08279.11 HTH domain 0.0022 17-39 / 14-36
PF01418.16 Helix-turn-helix domain, rpiR family 0.0023 18-39 / 34-55
PF07900.10 Protein of unknown function (DUF1670) 0.0025 16-40 / 93-117
PF11972.7 HTH DNA binding domain 0.0026 16-38 / 11-33
PF12802.6 MarR family 0.0031 19-39 / 22-42
PF14947.5 Winged helix-turn-helix 0.0032 17-39 / 15-37
PF13463.5 Winged helix DNA-binding domain 0.0034 17-38 / 16-37
PF02002.16 TFIIE alpha subunit 0.0035 16-39 / 24-47
PF08280.10 M protein trans-acting positive regulator (MGA) HTH domain 0.0036 17-39 / 19-41
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.0037 20-39 / 13-32
PF15977.4 Winged helix-turn-helix DNA binding 0.0041 18-39 / 23-44
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.0042 17-39 / 21-43
PF00196.18 Bacterial regulatory proteins, luxR family 0.0043 17-39 / 16-38
PF04703.11 FaeA-like protein 0.0053 17-38 / 13-34
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.0053 17-39 / 32-54
PF13384.5 Homeodomain-like domain 0.0056 18-39 / 17-38
PF05584.10 Sulfolobus plasmid regulatory protein 0.0056 16-39 / 16-39
PF00392.20 Bacterial regulatory proteins, gntR family 0.0058 17-39 / 22-45
PF06163.10 Bacterial protein of unknown function (DUF977) 0.0057 16-39 / 24-47
PF13551.5 Winged helix-turn helix 0.0065 18-39 / 11-32
PF06969.15 HemN C-terminal domain 0.0075 15-36 / 17-39
PF06530.11 Phage antitermination protein Q 0.0073 17-39 / 78-100
PF05732.10 Firmicute plasmid replication protein (RepL) 0.0079 17-39 / 74-96
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0085 17-39 / 20-42
PF04182.11 B-block binding subunit of TFIIIC 0.0092 17-39 / 17-39
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0093 17-39 / 16-38
PF16864.4 Dimerisation domain 0.0096 17-39 / 31-53
PF12324.7 Helix-turn-helix domain of alkylmercury lyase 0.0092 11-39 / 28-56

Annotations of the NCBI proteins of this PHROG


1:transcriptional regulator, 1:phage repressor fragment

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0019069 viral capsid assembly
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0051775 response to redox state
GO:0006352 DNA-templated transcription, initiation
GO:0004803 transposase activity
GO:0043565 sequence-specific DNA binding
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0006276 plasmid maintenance
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0016987 sigma factor activity
GO:0009289 pilus
GO:0045893 positive regulation of transcription, DNA-templated
GO:0006260 DNA replication
GO:0005622 intracellular
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0003700 DNA binding transcription factor activity

Loading in process