phrog_37920 is made of 2 protein sequences and is annotated as "HTH DNA binding protein"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
245 245 245


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KU160673_p72 ALY10855.1 HTH DNA binding domain protein KU160673 Arthrobacter phage Wilde Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tankvirus; unclassified Tankvirus.
KU160669_p70 ALY10605.1 HTH DNA binding domain protein KU160669 Arthrobacter phage Tank Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Tankvirus; Arthrobacter virus Tank.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_29419 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11718 no annotation unknown function 97.4 4.5E-07 2-78 / 3-78
phrog_1456 DNA binding protein DNA, RNA and nucleotide metabolism 96.9 6.2E-06 33-83 / 1-51
phrog_186 DnaD-like helicase loader DNA, RNA and nucleotide metabolism 95.6 0.00046 10-84 / 5-90
phrog_22134 no annotation unknown function 96.2 9.8E-05 16-77 / 3-64
phrog_23842 no annotation unknown function 96.7 1.4E-05 12-89 / 25-102
phrog_270 replication initiation protein DNA, RNA and nucleotide metabolism 93.5 0.0086 11-86 / 4-80
phrog_27492 no annotation unknown function 93.1 0.012 8-76 / 20-89
phrog_4221 replication initiation protein DNA, RNA and nucleotide metabolism 95.8 0.00031 2-89 / 4-90
phrog_428 replication initiation protein DNA, RNA and nucleotide metabolism 97.4 4.7E-07 9-82 / 10-86
phrog_4707 replication initiation protein DNA, RNA and nucleotide metabolism 98.4 1.8E-10 2-89 / 7-94
phrog_678 replication initiation O-like DNA, RNA and nucleotide metabolism 91.8 0.029 9-86 / 5-89

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF04492.12 Bacteriophage replication protein O 1.7E-05 22-79 / 22-84
PF16221.4 winged helix-turn-helix 4.3E-05 28-76 / 32-78
PF02319.19 E2F/DP family winged-helix DNA-binding domain 5.9E-05 45-78 / 24-57
PF04358.12 DsrC like protein 0.00013 22-78 / 34-95
PF05584.10 Sulfolobus plasmid regulatory protein 0.00016 25-79 / 4-53
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 0.00017 25-78 / 11-61
PF04079.15 Segregation and condensation complex subunit ScpB 0.00017 22-81 / 78-131
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 0.00018 25-78 / 6-56
PF05732.10 Firmicute plasmid replication protein (RepL) 0.00019 19-78 / 46-109
PF09012.9 FeoC like transcriptional regulator 0.00019 45-80 / 15-50
PF09114.9 Transcription factor MotA, activation domain 0.00026 23-78 / 12-65
PF08784.10 Replication protein A C terminal 0.00029 23-78 / 36-95
PF01726.15 LexA DNA binding domain 0.00035 45-79 / 26-61
PF14557.5 Putative AphA-like transcriptional regulator 0.00037 23-79 / 4-68
PF03965.15 Penicillinase repressor 0.00036 28-79 / 4-58
PF03551.13 Transcriptional regulator PadR-like family 0.00038 45-80 / 15-52
PF07381.10 Winged helix DNA-binding domain (DUF1495) 0.00039 25-79 / 7-69
PF03428.12 Replication protein C N-terminal domain 0.00044 16-79 / 32-106
PF01978.18 Sugar-specific transcriptional regulator TrmB 0.00044 25-78 / 6-56
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.00055 12-68 / 2-75
PF01475.18 Ferric uptake regulator family 0.00056 24-80 / 4-63
PF01047.21 MarR family 0.00057 45-79 / 18-52
PF08222.10 CodY helix-turn-helix domain 0.00059 45-78 / 5-38
PF01090.18 Ribosomal protein S19e 0.00063 31-79 / 55-115
PF02295.16 Adenosine deaminase z-alpha domain 0.00066 45-78 / 19-53
PF02002.16 TFIIE alpha subunit 0.00073 28-80 / 13-62
PF13463.5 Winged helix DNA-binding domain 0.00072 45-78 / 18-51
PF12802.6 MarR family 0.00073 45-79 / 22-56
PF04182.11 B-block binding subunit of TFIIIC 0.00079 45-79 / 19-53
PF11313.7 Protein of unknown function (DUF3116) 0.00085 45-80 / 21-63
PF06163.10 Bacterial protein of unknown function (DUF977) 0.001 28-79 / 13-61
PF13601.5 Winged helix DNA-binding domain 0.001 45-79 / 15-49
PF14277.5 Domain of unknown function (DUF4364) 0.0011 45-77 / 16-52
PF14394.5 Domain of unknown function (DUF4423) 0.0012 28-79 / 22-73
PF05158.11 RNA polymerase Rpc34 subunit 0.0013 24-79 / 89-143
PF05491.12 Holliday junction DNA helicase ruvB C-terminus 0.0014 25-78 / 6-60
PF14947.5 Winged helix-turn-helix 0.0015 45-78 / 17-50
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 0.0017 31-79 / 5-53
PF09824.8 ArsR transcriptional regulator 0.0019 26-78 / 16-62
PF13412.5 Winged helix-turn-helix DNA-binding 0.002 45-74 / 18-47
PF09904.8 Winged helix-turn helix 0.0023 45-77 / 22-54
PF12793.6 Sugar transport-related sRNA regulator N-term 0.0024 45-78 / 19-52
PF09202.10 Rio2, N-terminal 0.0024 26-78 / 5-58
PF01022.19 Bacterial regulatory protein, arsR family 0.0025 45-74 / 17-46
PF13730.5 Helix-turn-helix domain 0.0026 25-74 / 3-52
PF12840.6 Helix-turn-helix domain 0.0026 27-78 / 8-54
PF13034.5 Protein of unknown function (DUF3895) 0.0028 29-80 / 5-69
PF09639.9 YjcQ protein 0.0029 45-79 / 17-53
PF02334.15 Replication terminator protein 0.0032 45-80 / 32-76
PF14502.5 Helix-turn-helix domain 0.0033 45-78 / 7-40
PF02082.19 Transcriptional regulator 0.0034 45-77 / 25-57
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.0035 45-78 / 25-58
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 0.0039 25-78 / 3-63
PF15977.4 Winged helix-turn-helix DNA binding 0.0041 45-78 / 24-57
PF01638.16 HxlR-like helix-turn-helix 0.0042 45-79 / 20-55
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.005 25-80 / 6-58
PF09182.9 Bacterial purine repressor, N-terminal 0.0048 45-78 / 21-59
PF10711.8 Hypothetical protein (DUF2513) 0.005 45-80 / 19-58
PF09339.9 IclR helix-turn-helix domain 0.0049 45-77 / 19-51
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.0051 45-78 / 22-55
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.0058 45-77 / 18-50
PF05331.10 Protein of unknown function (DUF742) 0.0065 24-79 / 38-88
PF06969.15 HemN C-terminal domain 0.0065 45-77 / 21-54
PF07848.11 PaaX-like protein 0.0067 45-78 / 21-57
PF08220.11 DeoR-like helix-turn-helix domain 0.0075 45-77 / 15-47
PF00392.20 Bacterial regulatory proteins, gntR family 0.008 45-78 / 24-58

Annotations of the NCBI proteins of this PHROG


2:HTH DNA binding domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005622 intracellular
GO:0006260 DNA replication
GO:0006383 transcription by RNA polymerase III
GO:0004674 protein serine/threonine kinase activity
GO:0007131 reciprocal meiotic recombination
GO:0009378 four-way junction helicase activity
GO:0006468 protein phosphorylation
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0003700 DNA binding transcription factor activity
GO:0005840 ribosome
GO:0006274 DNA replication termination
GO:0006281 DNA repair
GO:0004252 serine-type endopeptidase activity
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0051304 chromosome separation
GO:0006355 regulation of transcription, DNA-templated
GO:0006412 translation
GO:0005666 DNA-directed RNA polymerase III complex
GO:0006508 proteolysis
GO:0006276 plasmid maintenance
GO:0005524 ATP binding

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