phrog_3949 is made of 36 protein sequences and is annotated as "transcriptional repressor"
Functional category: transcription regulation


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
161.89 199 177


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
JQ300538_p45 AFA45053.1 repressor JQ300538 Mycobacterium phage Spartacus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; Mycobacterium virus Spartacus.
MH051257_p43 AVR77283.1 immunity repressor MH051257 Mycobacterium phage OwlsT2W Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_011289_p46 YP_002241833.1 gp46 NC_011289 Mycobacterium virus Ramsey Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_026593_p50 YP_009125043.1 immunity repressor NC_026593 Mycobacterium phage BuzzLyseyear Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MG770213_p43 AUV60546.1 immunity repressor MG770213 Mycobacterium phage OldBen Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023746_p43 YP_009018919.1 gp43 NC_023746 Mycobacterium virus Gumbie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_028751_p52 YP_009194576.1 immunity repressor NC_028751 Mycobacterium phage Quico Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_028823_p41 YP_009200668.1 immunity repressor NC_028823 Mycobacterium phage Bipolar Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023580_p47 YP_009007514.1 immunity repressor NC_023580 Mycobacterium phage Saal Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_026595_p45 YP_009125224.1 immunity repressor NC_026595 Mycobacterium phage Hades Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
KR997931_p54 AKU45141.1 immunity repressor KR997931 Mycobacterium phage Girafales Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023728_p49 YP_009016939.1 gp49 NC_023728 Mycobacterium virus Deadp Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_022069_p57 YP_008410730.1 immunity repressor NC_022069 Mycobacterium phage Jabbawokkie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MG812488_p49 AUX81975.1 immunity repressor MG812488 Mycobacterium phage Frankie Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
MG962361_p50 AVO24549.1 immunity repressor MG962361 Mycobacterium phage Alexphander Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_014901_p48 YP_004123870.1 gp48 NC_014901 Mycobacterium phage Wee Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_021301_p45 YP_008051171.1 immunity repressor NC_021301 Mycobacterium phage SiSi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_009820_p45 YP_001469278.1 hypothetical protein NC_009820 Mycobacterium phage Tweety Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
KX576644_p45 AOQ28499.1 immunity repressor KX576644 Mycobacterium phage WillSterrel Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_023698_p53 YP_009013148.1 gp53 NC_023698 Mycobacterium virus Avani Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_022056_p46 YP_008409110.1 HTH domain protein NC_022056 Mycobacterium phage Hamulus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_021334_p39 YP_008059940.1 putative DNA-binding protein NC_021334 Mycobacterium phage WIVsmall Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
JN859129_p42 AER14088.1 hypothetical protein JN859129 Mycobacterium virus Dotproduct Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
KY092484_p31 APD18779.1 hypothetical protein KY092484 Streptomyces phage Raleigh Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Raleighvirus; Streptomyces virus Raleigh.
p35643 no NCBI prot ID no annotation VI_04143 Actinobacteria_gi_514922871 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Streptomyces phage VWB.
KY092482_p32 APD18673.1 hypothetical protein KY092482 Streptomyces phage Mojorita Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Picardvirus; unclassified Picardvirus.
KY092479_p32 APD18508.1 hypothetical protein KY092479 Streptomyces phage Ididsumtinwong Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Austintatiousvirus; Streptomyces virus Ididsumtinwong.
KY092480_p32 APD18562.1 hypothetical protein KY092480 Streptomyces phage Picard Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Picardvirus; Streptomyces virus Picard.
KY092483_p32 APD18727.1 hypothetical protein KY092483 Streptomyces phage Bioscum Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Austintatiousvirus; unclassified Austintatiousvirus.
NC_018848_p29 YP_006906971.1 hypothetical protein NC_018848 Streptomyces phage SV1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Picardvirus; unclassified Picardvirus.
KY092481_p31 APD18640.1 hypothetical protein KY092481 Streptomyces phage PapayaSalad Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Austintatiousvirus; Streptomyces virus PapayaSalad.
KX808131_p46 APC43541.1 immunity repressor KX808131 Mycobacterium phage SuperGrey Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
NC_011288_p44 YP_002241729.1 gp44 NC_011288 Mycobacterium virus Fruitloop Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_013936_p37 YP_003495179.1 gp38 NC_013936 Mycobacterium virus Ardmore Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.
NC_028889_p54 YP_009206772.1 immunity repressor NC_028889 Mycobacterium phage Florinda Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus; unclassified Cheoctovirus.
JF704115_p57 AEK07864.1 hypothetical protein JF704115 Mycobacterium virus Yoshi Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Cheoctovirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_1948 78 no annotation unknown function 20 7.34E-77 67.26
phrog_7613 15 no annotation unknown function 7 2.95E-32 22.65
phrog_12722 8 no annotation unknown function 7 4.58E-36 26.46

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_13326 no annotation unknown function 96.7 1.5E-05 29-114 / 18-91
phrog_1373 transcriptional regulator transcription regulation 96.4 4.5E-05 30-72 / 46-89
phrog_1381 plasmid antitoxin with HTH domain moron, auxiliary metabolic gene and host takeover 92.0 0.025 30-69 / 25-65
phrog_16278 HTH DNA binding protein DNA, RNA and nucleotide metabolism 97.9 1.7E-08 14-113 / 2-98
phrog_1702 transcriptional repressor transcription regulation 96.1 0.00012 16-78 / 10-80
phrog_1746 transcriptional repressor transcription regulation 95.2 0.00097 32-88 / 26-83
phrog_18104 transcriptional regulator transcription regulation 90.4 0.056 30-67 / 15-53
phrog_18342 transcriptional repressor transcription regulation 93.4 0.0094 30-74 / 32-79
phrog_18815 no annotation unknown function 96.0 0.00015 14-111 / 1-97
phrog_19097 transcriptional repressor transcription regulation 96.0 0.00017 30-111 / 20-101
phrog_19579 transcriptional regulator transcription regulation 99.7 3.6E-21 16-112 / 2-100
phrog_20450 transcriptional repressor transcription regulation 91.3 0.036 30-151 / 41-148
phrog_2328 transcriptional repressor transcription regulation 96.3 5.7E-05 20-80 / 16-79
phrog_23446 no annotation unknown function 92.8 0.015 16-62 / 1-49
phrog_2439 transcriptional regulator transcription regulation 94.2 0.0043 30-71 / 21-63
phrog_2838 transcriptional repressor transcription regulation 100.0 1.1E-40 38-176 / 74-207
phrog_2967 transcriptional regulator transcription regulation 95.8 0.00025 14-75 / 7-70
phrog_3037 transcriptional repressor transcription regulation 92.8 0.015 30-71 / 29-71
phrog_3557 transcriptional regulator transcription regulation 92.4 0.02 30-73 / 27-71
phrog_35 transcriptional repressor transcription regulation 94.4 0.0034 28-66 / 13-52
phrog_3638 CII-like transcriptional activator transcription regulation 95.4 0.0007 16-62 / 15-59
phrog_3642 HTH DNA binding protein DNA, RNA and nucleotide metabolism 94.6 0.0028 28-74 / 20-67
phrog_3 transcriptional repressor transcription regulation 95.2 0.001 30-76 / 18-65
phrog_4441 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.6 0.00044 19-90 / 8-83
phrog_4583 transcriptional repressor transcription regulation 94.8 0.0021 24-76 / 19-72
phrog_4779 transcriptional regulator transcription regulation 91.5 0.033 30-58 / 16-44
phrog_4836 CII-like regulator transcription regulation 90.7 0.049 18-82 / 82-148
phrog_4 transcriptional repressor transcription regulation 94.5 0.0029 31-82 / 17-67
phrog_5301 transcriptional repressor transcription regulation 99.4 2.1E-16 16-117 / 6-116
phrog_5414 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.7 0.048 30-73 / 22-66
phrog_5823 transcriptional regulator transcription regulation 91.9 0.027 30-76 / 19-67
phrog_6223 transcriptional repressor transcription regulation 92.9 0.015 30-59 / 19-48
phrog_638 transcriptional regulator transcription regulation 96.4 5E-05 20-78 / 7-67
phrog_7126 HTH DNA binding protein DNA, RNA and nucleotide metabolism 93.1 0.013 13-75 / 12-78
phrog_7241 transcriptional regulator transcription regulation 95.3 0.00079 30-74 / 76-121
phrog_725 CII-like regulator transcription regulation 90.6 0.05 30-70 / 29-67
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 91.0 0.043 30-121 / 19-85
phrog_8 transcriptional regulator transcription regulation 96.1 0.00013 32-77 / 17-62
phrog_9103 transcriptional repressor transcription regulation 95.8 0.00029 30-76 / 22-69

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 3.8E-05 88-123 / 12-47
PF13744.5 Helix-turn-helix domain 0.0014 93-123 / 25-55
PF01381.21 Helix-turn-helix 0.00025 96-125 / 6-35
PF14590.5 Domain of unknown function (DUF4447) 0.00092 91-125 / 12-46
PF07022.12 Bacteriophage CI repressor helix-turn-helix domain 0.0016 97-144 / 9-54
PF05339.10 Protein of unknown function (DUF739) 0.00092 94-125 / 11-42
PF13413.5 Helix-turn-helix domain 9.5E-05 95-125 / 5-35
PF12844.6 Helix-turn-helix domain 0.0028 96-125 / 9-38
PF04645.11 Protein of unknown function, DUF603 0.0014 89-126 / 10-50
PF08667.9 BetR domain 6.1E-06 15-79 / 5-72
PF15731.4 Antitoxin component of bacterial toxin-antitoxin system, MqsA 0.0054 93-125 / 76-108
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0027 96-123 / 7-36
PF05269.10 Bacteriophage CII protein 9.5E-06 21-78 / 16-70
PF13560.5 Helix-turn-helix domain 0.0048 94-125 / 9-40
PF04936.11 Protein of unknown function (DUF658) 3.5E-05 28-123 / 14-112
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 3.5E-05 31-78 / 10-57
PF08965.9 Domain of unknown function (DUF1870) 0.0022 91-125 / 6-42
PF12116.7 Stage III sporulation protein D 0.0074 98-123 / 18-43
PF13693.5 Winged helix-turn-helix DNA-binding 0.0001 19-77 / 6-60
PF04552.12 Sigma-54, DNA binding domain 0.00021 26-54 / 46-73
PF04814.12 Hepatocyte nuclear factor 1 (HNF-1), N terminus 0.0079 92-125 / 119-152
PF00356.20 Bacterial regulatory proteins, lacI family 0.0011 101-125 / 1-25
PF00157.16 Pou domain - N-terminal to homeobox domain 0.00033 15-69 / 7-64
PF14549.5 DNA-binding transcriptional regulator Cro 0.0074 95-125 / 6-33
PF10654.8 Protein of unknown function (DUF2481) 0.00059 97-125 / 78-106
PF02376.14 CUT domain 0.00057 15-77 / 7-67
PF00376.22 MerR family regulatory protein 0.0078 101-125 / 1-25
PF01710.15 Transposase 0.006 27-122 / 17-93
PF08535.9 KorB domain 0.0061 98-125 / 2-29
PF06322.10 Phage NinH protein 0.0063 21-54 / 9-41
PF06806.11 Putative excisionase (DUF1233) 0.0066 97-123 / 7-33
PF02042.14 RWP-RK domain 0.0066 22-54 / 6-37
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 0.0079 27-54 / 12-38

Annotations of the NCBI proteins of this PHROG


16:immunity repressor 16:hypothetical protein 1:DNA-binding protein 1:HTH domain protein 1:repressor

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0003700 DNA binding transcription factor activity
GO:0019069 viral capsid assembly
GO:0045892 negative regulation of transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated

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