phrog_3953 is made of 36 protein sequences and is annotated as "exonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
194.08 338 186


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
KR296689_p3 AKJ74066.1 hypothetical protein KR296689 Salmonella phage 35 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Chivirus; unclassified Chivirus.
p371276 no NCBI prot ID no annotation VI_11800 Gammaproteobacteria_gi_565818771 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Podoviridae; unclassified Podoviridae; Xylella phage Xfas53.
p373703 no NCBI prot ID no annotation VI_04839 Bacilli_gi_419786064 Viruses.
p46480 no NCBI prot ID no annotation VI_01201 Clostridia_gi_365137247_641329_700297 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF467948_p80 ASU03992.1 ATP-dependent helicase MF467948 Streptomyces phage DrGrey Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rimavirus; Strepomyces virus Drgrey.
MG962369_p91 AVO25423.1 exonuclease MG962369 Gordonia phage Kerry Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF140401_p84 ASR83377.1 RecB-like exonuclease MF140401 Arthrobacter phage Caterpillar Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; unclassified Gordonvirus.
MF140432_p86 ASR84079.1 RecB-like exonuclease MF140432 Arthrobacter phage Teacup Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; unclassified Gordonvirus.
KX670790_p85 AOZ65037.1 ATP-dependent helicase KX670790 Streptomyces phage Rima Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rimavirus; Strepomyces virus Rima.
MG757154_p85 AVD99507.1 exonuclease MG757154 Streptomyces phage Bing Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bingvirus; Streptomyces virus Bing.
MF467949_p83 ASU04078.1 ATP-dependent helicase MF467949 Streptomyces phage Spectropatronm Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rimavirus; unclassified Rimavirus.
NC_024214_p77 YP_009036820.1 hypothetical protein NC_024214 Lactococcus phage P162 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MF189170_p95 ASR80057.1 exonuclease MF189170 Arthrobacter phage Arcadia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
MF189175_p100 ASR80550.1 exonuclease MF189175 Arthrobacter phage Tribby Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
NC_023694_p105 YP_009012686.1 gp105 NC_023694 Rhodococcus phage ReqiPoco6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Pepyhexavirus.
MF038790_p91 ASD52306.1 ATP-dependent helicase MF038790 Arthrobacter phage Niktson Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; unclassified Gordonvirus.
NC_031224_p93 YP_009300782.1 exonuclease NC_031224 Arthrobacter phage Mudcat Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus.
KU160642_p97 ALY08778.1 hypothetical protein KU160642 Arthrobacter phage Circum Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; Arthrobacter virus Circum.
MF140423_p90 ASM62362.1 RecB-like exonuclease MF140423 Arthrobacter phage Nightmare Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; unclassified Gordonvirus.
p46224 no NCBI prot ID no annotation VI_01226 Clostridia_gi_547240599 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_024208_p75 YP_009035890.1 hypothetical protein NC_024208 Lactococcus phage P118 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MF975637_p54 ATN93703.1 DNA helicase MF975637 Streptomyces phage Scap1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Scapunavirus; Streptomyces virus Scap1.
KX670789_p86 AOZ64950.1 ATP-dependent helicase KX670789 Streptomyces phage OlympicHelado Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rimavirus; unclassified Rimavirus.
MF189173_p98 ASR80352.1 exonuclease MF189173 Arthrobacter phage Heisenberger Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
p18819 no NCBI prot ID no annotation VI_01149 Clostridia_gi_324035751_41009_118330 Viruses.
p38918 no NCBI prot ID no annotation VI_01187 Clostridia_gi_355689648_74587_135725 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_024203_p71 YP_009035132.1 hypothetical protein NC_024203 Lactococcus phage P092 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_010576_p69 YP_001828717.1 hypothetical protein NC_010576 Lactococcus phage 1706 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KU160646_p87 ALY09062.1 ATP-dependent helicase KU160646 Arthrobacter phage Gordon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; Arthrobacter virus Gordon.
NC_023735_p105 YP_009017719.1 gp105 NC_023735 Rhodococcus phage ReqiPepy6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Pepyhexavirus.
MF189171_p94 ASR80151.1 exonuclease MF189171 Arthrobacter phage Correa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
KU160641_p86 ALY08686.1 hypothetical protein KU160641 Arthrobacter phage CaptnMurica Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; Arthrobacter virus Captnmurica.
MF324906_p99 ASR84678.1 exonuclease MF324906 Arthrobacter phage Cheesy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
NC_024215_p73 YP_009036898.1 hypothetical protein NC_024215 Lactococcus phage P078 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p349504 no NCBI prot ID no annotation VI_02641 Gammaproteobacteria_gi_374683971_0_19856 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
MG711463_p54 AUV56547.1 cas4 family nuclease MG711463 Faecalibacterium phage FP_oengus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Oengusvirus; Faecalibacterium virus Oengus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_93 952 endonuclease DNA, RNA and nucleotide metabolism 28 2.18E-67 57.78
phrog_4291 32 RNA-dependent RNA polymerase DNA, RNA and nucleotide metabolism 27 9.67E-114 104.14
phrog_4997 26 no annotation unknown function 4 1.74E-16 6.88
phrog_22968 3 no annotation unknown function 3 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1218 exonuclease DNA, RNA and nucleotide metabolism 90.3 0.056 15-129 / 9-182
phrog_298 exonuclease DNA, RNA and nucleotide metabolism 97.5 3.2E-07 36-139 / 65-184
phrog_466 exonuclease DNA, RNA and nucleotide metabolism 96.2 0.0001 24-127 / 182-304
phrog_69 exonuclease DNA, RNA and nucleotide metabolism 99.9 7.8E-28 9-177 / 2-209

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF10926.7 Protein of unknown function (DUF2800) 5.7E-19 22-240 / 3-231
PF12705.6 PD-(D/E)XK nuclease superfamily 8.2E-18 23-236 / 2-243
PF09810.8 Exonuclease V - a 5' deoxyribonuclease 4.8E-17 20-167 / 11-205
PF06023.11 CRISPR-associated exonuclease Csa1 5.3E-16 19-236 / 44-281
PF01930.16 Domain of unknown function DUF83 5.4E-16 24-237 / 1-160
PF12684.6 PDDEXK-like domain of unknown function (DUF3799) 4.3E-15 24-166 / 1-167
PF08696.10 DNA replication factor Dna2 6.6E-07 20-68 / 64-115
PF07999.10 Retrotransposon hot spot protein 0.0039 268-284 / 127-143

Annotations of the NCBI proteins of this PHROG


8:exonuclease 8:hypothetical protein 6:ATP-dependent helicase 3:RecB-like exonuclease 2:protein of an unannotated phage 1:cas4 family nuclease 1:DNA helicase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity

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