phrog_4121 is made of 34 protein sequences and is annotated as "thymidylate kinase"
Functional category: other


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
195.91 201 197


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MG944222_p46 AVJ51491.1 hypothetical protein MG944222 Microbacterium phage StingRay Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839024_p47 AUX83197.1 hypothetical protein MG839024 Microbacterium phage Peppino Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839019_p47 AUX82883.1 hypothetical protein MG839019 Microbacterium phage Hamlet Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; Microbacterium virus Hamlet.
MG925352_p46 AVJ50519.1 hypothetical protein MG925352 Microbacterium phage Nattles Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839030_p46 AUX83572.1 hypothetical protein MG839030 Microbacterium phage Balsa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839015_p46 AUX82633.1 hypothetical protein MG839015 Microbacterium phage Aubergine Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839018_p46 AUX82820.1 pantohenate kinase-like domain protein MG839018 Microbacterium phage Espinosa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045563_p47 AVR56527.1 hypothetical protein MH045563 Microbacterium phage Robinson Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839029_p46 AUX83510.1 hypothetical protein MG839029 Microbacterium phage Ilzat Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; Microbacterium virus Ilzat.
MG944219_p47 AVJ51244.1 hypothetical protein MG944219 Microbacterium phage PuppyEggo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG944216_p44 AVJ51035.1 thymidylate kinase MG944216 Microbacterium phage Pajaza Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Pikminvirus; unclassified Pikminvirus.
MG962360_p47 AVO24438.1 hypothetical protein MG962360 Microbacterium phage AlexAdler Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045562_p47 AVR56464.1 hypothetical protein MH045562 Microbacterium phage Raptor Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG962367_p46 AVO25224.1 hypothetical protein MG962367 Microbacterium phage Gelo Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045560_p47 AVR56375.1 hypothetical protein MH045560 Microbacterium phage Nagem Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839016_p47 AUX82696.1 hypothetical protein MG839016 Microbacterium phage AxiPup Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839017_p46 AUX82758.1 hypothetical protein MG839017 Microbacterium phage Baines Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045554_p47 AVR56069.1 hypothetical protein MH045554 Microbacterium phage Bandik Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839026_p47 AUX83323.1 hypothetical protein MG839026 Microbacterium phage Superfresh Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839020_p46 AUX82945.1 hypothetical protein MG839020 Microbacterium phage Kale Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG944218_p44 AVJ51182.1 thymidylate kinase MG944218 Microbacterium phage Pikmin Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Pikminvirus; Microbacterium virus Pikmin.
MG925345_p44 AVJ49942.1 thymidylate kinase MG925345 Microbacterium phage Koji Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Kojivirus; Microbacterium virus Koji.
MH045558_p47 AVR56249.1 hypothetical protein MH045558 Microbacterium phage Dave Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045559_p47 AVR56312.1 hypothetical protein MH045559 Microbacterium phage Etna Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839021_p47 AUX83008.1 hypothetical protein MG839021 Microbacterium phage Knox Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839027_p45 AUX83383.1 hypothetical protein MG839027 Microbacterium phage Eleri Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Elerivirus; Microbacterium virus Eleri.
MG839022_p47 AUX83071.1 hypothetical protein MG839022 Microbacterium phage Ludgate Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG925343_p44 AVJ49791.1 thymidylate kinase MG925343 Microbacterium phage Golden Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Kojivirus; Microbacterium virus Golden.
MG839023_p47 AUX83133.1 hypothetical protein MG839023 Microbacterium phage Peep Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG839025_p47 AUX83260.1 hypothetical protein MG839025 Microbacterium phage Raccoon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045565_p47 AVR56652.1 hypothetical protein MH045565 Microbacterium phage Antoinette Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045555_p48 AVR56133.1 hypothetical protein MH045555 Microbacterium phage BeeBee8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MH045564_p46 AVR56589.1 hypothetical protein MH045564 Microbacterium phage TeddyBear Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.
MG920061_p46 AVJ49248.1 hypothetical protein MG920061 Microbacterium phage Bonino Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Ilzatvirus; unclassified Ilzatvirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_4086 34 no annotation unknown function 34 0 1000
phrog_4519 30 glycosyltransferase moron, auxiliary metabolic gene and host takeover 30 0 1000
phrog_19208 4 no annotation unknown function 2 1.65E-12 2.9
phrog_28776 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 91.5 0.034 3-134 / 17-182
phrog_139 deoxynucleoside monophosphate kinase other 93.9 0.0062 1-24 / 3-26
phrog_16057 thymidylate kinase other 91.1 0.041 2-21 / 5-24
phrog_164 ParA-like partition protein DNA, RNA and nucleotide metabolism 90.5 0.054 8-23 / 11-26
phrog_168 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 91.4 0.035 4-61 / 42-113
phrog_1815 guanylate kinase other 91.7 0.03 1-24 / 3-27
phrog_2071 ATPase other 95.6 0.00041 1-29 / 4-33
phrog_2107 thymidylate kinase other 92.3 0.022 2-23 / 5-26
phrog_2392 ABC transporter moron, auxiliary metabolic gene and host takeover 91.7 0.03 2-22 / 371-391
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 92.7 0.017 111-166 / 148-196
phrog_3757 no annotation unknown function 92.1 0.024 3-58 / 129-196
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 93.6 0.008 2-23 / 40-61
phrog_7485 no annotation unknown function 93.3 0.011 4-28 / 231-256
phrog_761 thymidylate kinase other 97.7 9.6E-08 1-129 / 3-165

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00406.21 Adenylate kinase 5.3E-09 5-28 / 1-24
PF01712.18 Deoxynucleoside kinase 2E-08 3-100 / 1-133
PF13671.5 AAA domain 3E-08 2-26 / 1-25
PF08433.9 Chromatin associated protein KTI12 9.6E-08 2-124 / 3-141
PF02223.16 Thymidylate kinase 1.1E-07 5-100 / 1-136
PF06414.11 Zeta toxin 1.5E-07 2-24 / 16-38
PF03976.13 Polyphosphate kinase 2 (PPK2) 2.9E-07 2-100 / 30-150
PF13238.5 AAA domain 4.8E-07 3-26 / 1-24
PF01591.17 6-phosphofructo-2-kinase 1.1E-06 2-26 / 11-35
PF07931.11 Chloramphenicol phosphotransferase-like protein 1.5E-06 2-27 / 3-28
PF00693.17 Thymidine kinase from herpesvirus 1.8E-06 47-127 / 105-194
PF00625.20 Guanylate kinase 3E-06 2-25 / 4-27
PF01583.19 Adenylylsulphate kinase 3.7E-06 2-24 / 4-26
PF13207.5 AAA domain 5.6E-06 6-29 / 1-24
PF03668.14 P-loop ATPase protein family 6.1E-05 2-28 / 3-28
PF13521.5 AAA domain 6.3E-05 2-95 / 1-126
PF01745.15 Isopentenyl transferase 0.0001 2-28 / 3-29
PF13189.5 Cytidylate kinase-like family 0.0001 2-29 / 1-28
PF01121.19 Dephospho-CoA kinase 0.00014 2-29 / 2-29
PF00910.21 RNA helicase 0.00021 3-25 / 1-23
PF06431.10 Polyomavirus large T antigen C-terminus 0.00023 2-30 / 157-185
PF02224.17 Cytidylate kinase 0.00024 3-29 / 1-27
PF13173.5 AAA domain 0.00029 2-23 / 4-25
PF05729.11 NACHT domain 0.00029 2-24 / 2-24
PF03266.14 NTPase 0.00032 3-24 / 2-23
PF08303.10 tRNA ligase kinase domain 0.0004 2-25 / 1-24
PF07726.10 ATPase family associated with various cellular activities (AAA) 0.00046 3-26 / 2-25
PF00485.17 Phosphoribulokinase / Uridine kinase family 0.00049 2-25 / 1-24
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 0.0005 2-29 / 34-61
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 0.0005 2-26 / 47-71
PF00308.17 Bacterial dnaA protein 0.00051 2-24 / 35-57
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.00053 3-26 / 1-24
PF10649.8 Protein of unknown function (DUF2478) 0.00057 3-25 / 1-23
PF03215.14 Rad17 cell cycle checkpoint protein 0.00058 2-27 / 47-72
PF12780.6 P-loop containing dynein motor region D4 0.00065 2-30 / 33-61
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.00065 3-25 / 1-23
PF07728.13 AAA domain (dynein-related subfamily) 0.00065 3-25 / 2-24
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.00068 2-24 / 6-28
PF05621.10 Bacterial TniB protein 0.00067 2-24 / 40-62
PF05272.10 Virulence-associated protein E 0.00075 2-24 / 61-83
PF00158.25 Sigma-54 interaction domain 0.00077 2-25 / 24-47
PF12775.6 P-loop containing dynein motor region D3 0.00079 2-25 / 35-58
PF01637.17 ATPase domain predominantly from Archaea 0.00078 2-24 / 22-44
PF04275.13 Phosphomevalonate kinase 0.00084 5-24 / 1-20
PF03969.15 AFG1-like ATPase 0.00086 2-25 / 69-92
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.00095 2-24 / 2-24
PF04851.14 Type III restriction enzyme, res subunit 0.00096 2-24 / 25-47
PF01443.17 Viral (Superfamily 1) RNA helicase 0.0012 3-23 / 1-20
PF13401.5 AAA domain 0.0012 2-24 / 7-29
PF09820.8 Predicted AAA-ATPase 0.0012 2-24 / 33-55
PF05673.12 Protein of unknown function (DUF815) 0.0013 2-24 / 56-78
PF00519.16 Papillomavirus helicase 0.0014 2-28 / 264-290
PF00493.22 MCM2/3/5 family 0.0013 2-26 / 59-83
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.0015 2-25 / 16-39
PF01078.20 Magnesium chelatase, subunit ChlI 0.0017 2-25 / 24-47
PF14516.5 AAA-like domain 0.0018 2-24 / 32-54
PF13177.5 DNA polymerase III, delta subunit 0.002 2-25 / 21-44
PF14532.5 Sigma-54 interaction domain 0.0019 2-25 / 23-46
PF01695.16 IstB-like ATP binding protein 0.002 2-24 / 50-72
PF04665.11 Poxvirus A32 protein 0.0021 2-24 / 15-37
PF07693.13 KAP family P-loop domain 0.0022 2-25 / 33-56
PF13191.5 AAA ATPase domain 0.0022 2-25 / 26-49
PF09848.8 Uncharacterized conserved protein (DUF2075) 0.0024 2-24 / 3-25
PF00931.21 NB-ARC domain 0.0027 2-24 / 22-44
PF00265.17 Thymidine kinase 0.0028 2-24 / 3-25
PF13654.5 AAA domain 0.0032 2-25 / 26-49
PF01926.22 50S ribosome-binding GTPase 0.0032 3-23 / 2-22
PF10443.8 RNA12 protein 0.0032 2-24 / 19-42
PF01057.16 Parvovirus non-structural protein NS1 0.0033 2-25 / 120-143
PF07475.11 HPr Serine kinase C-terminal domain 0.0035 2-23 / 16-37
PF02562.15 PhoH-like protein 0.0036 2-22 / 21-41
PF07724.13 AAA domain (Cdc48 subfamily) 0.0036 2-24 / 5-27
PF05707.11 Zonular occludens toxin (Zot) 0.0038 2-20 / 2-20
PF13337.5 Putative ATP-dependent Lon protease 0.0048 2-25 / 208-231
PF13245.5 AAA domain 0.0051 2-24 / 13-35
PF02492.18 CobW/HypB/UreG, nucleotide-binding domain 0.0051 2-21 / 2-21
PF01202.21 Shikimate kinase 0.0053 9-29 / 1-21
PF10923.7 P-loop Domain of unknown function (DUF2791) 0.0055 2-24 / 51-73
PF00448.21 SRP54-type protein, GTPase domain 0.0058 2-24 / 3-25
PF13604.5 AAA domain 0.0067 3-20 / 19-36
PF06745.12 KaiC 0.0068 2-24 / 21-43

Annotations of the NCBI proteins of this PHROG


29:hypothetical protein 4:thymidylate kinase 1:pantohenate kinase-like domain protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0004672 protein kinase activity
GO:0009058 biosynthetic process
GO:0000155 phosphorelay sensor kinase activity
GO:0004797 thymidine kinase activity
GO:0005525 GTP binding
GO:0004631 phosphomevalonate kinase activity
GO:0019079 viral genome replication
GO:0006281 DNA repair
GO:0008152 metabolic process
GO:0016301 kinase activity
GO:0004003 ATP-dependent DNA helicase activity
GO:0006109 regulation of carbohydrate metabolic process
GO:0003723 RNA binding
GO:0006230 TMP biosynthetic process
GO:0005524 ATP binding
GO:0003873 6-phosphofructo-2-kinase activity
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0004127 cytidylate kinase activity
GO:0006260 DNA replication
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0004161 dimethylallyltranstransferase activity
GO:0006695 cholesterol biosynthetic process
GO:0004673 protein histidine kinase activity
GO:0003972 RNA ligase (ATP) activity
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0016740 transferase activity
GO:0006000 fructose metabolic process
GO:0000166 nucleotide binding
GO:0015937 coenzyme A biosynthetic process
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0016020 membrane
GO:0003724 RNA helicase activity
GO:0006139 nucleobase-containing compound metabolic process
GO:0051188 cofactor biosynthetic process
GO:0006270 DNA replication initiation
GO:0016887 ATPase activity
GO:0004140 dephospho-CoA kinase activity
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0043531 ADP binding
GO:0008134 transcription factor binding
GO:0000160 phosphorelay signal transduction system
GO:0009236 cobalamin biosynthetic process

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