phrog_4210 is made of 33 protein sequences and is annotated as "DNA polymerase"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
1332.39 1642 1302


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
MG757154_p64 AVD99486.1 DNA primase/polymerase MG757154 Streptomyces phage Bing Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Bingvirus; Streptomyces virus Bing.
MF975637_p42 ATN93691.1 DNA primase/polymerase MF975637 Streptomyces phage Scap1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Scapunavirus; Streptomyces virus Scap1.
MF140423_p58 ASM62334.1 DNA primase/polymerase MF140423 Arthrobacter phage Nightmare Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; unclassified Gordonvirus.
NC_024208_p53 YP_009035868.1 hypothetical protein NC_024208 Lactococcus phage P118 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_031224_p58 YP_009300747.1 DNA polymerase/primase NC_031224 Arthrobacter phage Mudcat Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus.
MF189171_p58 ASR80119.1 DNA polymerase/primase MF189171 Arthrobacter phage Correa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
KU160642_p63 ALY08747.1 DNA polymerase/primase KU160642 Arthrobacter phage Circum Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; Arthrobacter virus Circum.
KU160646_p54 ALY09029.1 DNA polymerase/primase KU160646 Arthrobacter phage Gordon Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; Arthrobacter virus Gordon.
p25529 no NCBI prot ID no annotation VI_01160 Clostridia_gi_211596895_66269_137690 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF189170_p61 ASR80024.1 DNA polymerase/primase MF189170 Arthrobacter phage Arcadia Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
KX670789_p60 AOZ64925.1 DNA polymerase/primase KX670789 Streptomyces phage OlympicHelado Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rimavirus; unclassified Rimavirus.
MF467949_p60 ASU04055.1 DNA polymerase/primase MF467949 Streptomyces phage Spectropatronm Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rimavirus; unclassified Rimavirus.
NC_010576_p55 YP_001828703.1 putative helicase NC_010576 Lactococcus phage 1706 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MG962369_p61 AVO25394.1 hypothetical protein MG962369 Gordonia phage Kerry Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF189173_p60 ASR80314.1 DNA polymerase/primase MF189173 Arthrobacter phage Heisenberger Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
NC_023735_p72 YP_009017686.1 gp072 NC_023735 Rhodococcus phage ReqiPepy6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Pepyhexavirus.
MF324906_p61 ASR84640.1 DNA polymerase/primase MF324906 Arthrobacter phage Cheesy Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
NC_024214_p54 YP_009036797.1 hypothetical protein NC_024214 Lactococcus phage P162 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
MF140401_p54 ASR83350.1 DNA polymerase/primase MF140401 Arthrobacter phage Caterpillar Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; unclassified Gordonvirus.
MF189175_p63 ASR80514.1 DNA polymerase/primase MF189175 Arthrobacter phage Tribby Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Mudcatvirus; unclassified Mudcatvirus.
MF140432_p57 ASR84057.1 DNA polymerase/primase MF140432 Arthrobacter phage Teacup Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; unclassified Gordonvirus.
MF038790_p56 ASD52278.1 DNA polymerae/primase MF038790 Arthrobacter phage Niktson Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; unclassified Gordonvirus.
NC_024215_p51 YP_009036876.1 hypothetical protein NC_024215 Lactococcus phage P078 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KU160641_p54 ALY08654.1 DNA polymerase/primase KU160641 Arthrobacter phage CaptnMurica Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Gordonvirus; Arthrobacter virus Captnmurica.
p218742 no NCBI prot ID no annotation VI_01171 Clostridia_gi_237642738 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p38944 no NCBI prot ID no annotation VI_01187 Clostridia_gi_355689648_74587_135725 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_023694_p72 YP_009012653.1 gp072 NC_023694 Rhodococcus phage ReqiPoco6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Pepyhexavirus.
p18845 no NCBI prot ID no annotation VI_01149 Clostridia_gi_324035751_41009_118330 Viruses.
KX670790_p61 AOZ65013.1 DNA polymerase/primase KX670790 Streptomyces phage Rima Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rimavirus; Strepomyces virus Rima.
MG711463_p28 AUV56521.1 helicase/polymerase MG711463 Faecalibacterium phage FP_oengus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Oengusvirus; Faecalibacterium virus Oengus.
p46461 no NCBI prot ID no annotation VI_01201 Clostridia_gi_365137247_641329_700297 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF467948_p59 ASU03972.1 DNA polymerase/primase MF467948 Streptomyces phage DrGrey Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Rimavirus; Strepomyces virus Drgrey.
NC_024203_p50 YP_009035111.1 hypothetical protein NC_024203 Lactococcus phage P092 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_4678 29 no annotation unknown function 22 3.15E-92 82.62
phrog_15586 6 no annotation unknown function 5 1.12E-25 16.07
phrog_16856 5 no annotation unknown function 5 0 1000
phrog_21647 4 no annotation unknown function 4 0 1000
phrog_19543 4 no annotation unknown function 4 0 1000
phrog_21864 4 no annotation unknown function 4 0 1000
phrog_4787 28 single strand annealing protein DNA, RNA and nucleotide metabolism 4 1.65E-16 6.9
phrog_14033 7 no annotation unknown function 3 8.67E-16 6.18
phrog_19221 4 no annotation unknown function 2 1.44E-12 2.96
phrog_33560 2 no annotation unknown function 2 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_1139 DNA primase DNA, RNA and nucleotide metabolism 96.7 1.8E-05 137-296 / 504-673
phrog_1156 DNA primase DNA, RNA and nucleotide metabolism 99.5 1.1E-17 120-425 / 460-778
phrog_1252 DNA polymerase DNA, RNA and nucleotide metabolism 100.0 7.3E-36 715-1273 / 6-598
phrog_14322 no annotation unknown function 92.5 0.019 174-311 / 195-321
phrog_1829 DNA primase DNA, RNA and nucleotide metabolism 99.0 2.5E-13 119-405 / 446-741
phrog_1883 DNA helicase DNA, RNA and nucleotide metabolism 90.8 0.047 121-303 / 443-628
phrog_2071 ATPase other 92.3 0.021 174-244 / 4-82
phrog_2249 DNA primase DNA, RNA and nucleotide metabolism 95.8 0.00027 165-397 / 505-740
phrog_2478 DNA polymerase/primase DNA, RNA and nucleotide metabolism 93.8 0.0067 120-417 / 544-850
phrog_262 DNA polymerase DNA, RNA and nucleotide metabolism 97.5 2.2E-07 761-1153 / 185-659
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 92.1 0.024 162-200 / 25-65
phrog_325 Dda-like helicase DNA, RNA and nucleotide metabolism 93.1 0.012 129-198 / 2-50
phrog_36509 DNA primase DNA, RNA and nucleotide metabolism 94.4 0.0033 165-303 / 566-701
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 91.6 0.032 168-201 / 33-66
phrog_6088 DNA primase DNA, RNA and nucleotide metabolism 98.7 1.1E-11 12-401 / 338-758
phrog_695 DNA polymerase/primase DNA, RNA and nucleotide metabolism 93.3 0.01 514-582 / 58-126
phrog_7485 no annotation unknown function 93.6 0.0082 177-341 / 231-380
phrog_7601 no annotation unknown function 98.7 1.1E-11 160-401 / 8-254
phrog_800 terminase small subunit head and packaging 91.8 0.028 173-199 / 8-34
phrog_8323 no annotation unknown function 90.6 0.051 172-201 / 48-77
phrog_864 DNA primase DNA, RNA and nucleotide metabolism 99.6 1E-19 108-418 / 167-498
phrog_9172 no annotation unknown function 95.1 0.0013 174-291 / 98-227

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00136.20 DNA polymerase family B 4.1E-23 925-1135 / 43-315
PF08490.11 Domain of unknown function (DUF1744) 2.9E-12 928-1115 / 186-399
PF03175.12 DNA polymerase type B, organellar and viral 3E-11 839-962 / 141-254
PF04735.11 Baculovirus DNA helicase 2.5E-10 141-366 / 863-1120
PF03337.12 Poxvirus F12L protein 5.8E-09 1009-1076 / 551-618
PF05272.10 Virulence-associated protein E 5.8E-07 159-303 / 35-177
PF03104.18 DNA polymerase family B, exonuclease domain 3.5E-05 749-819 / 254-333
PF06048.10 Domain of unknown function (DUF927) 7.3E-05 28-204 / 54-215
PF10108.8 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 0.0003 749-862 / 53-174
PF00519.16 Papillomavirus helicase 0.00052 177-303 / 262-382
PF01057.16 Parvovirus non-structural protein NS1 0.00084 176-302 / 117-242

Annotations of the NCBI proteins of this PHROG


15:DNA polymerase/primase 5:hypothetical protein 3:DNA primase/polymerase 2:protein of an unannotated phage 1:helicase 1:helicase/polymerase 1:DNA polymerae/primase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K02327 POLD1 : DNA polymerase delta subunit 1 [EC:2.7.7.7] ko00230 Purine metabolism
ko00240 Pyrimidine metabolism
ko03030 DNA replication
ko03410 Base excision repair
ko03420 Nucleotide excision repair
ko03430 Mismatch repair
ko03440 Homologous recombination
ko05166 HTLV-I infection
61 1
K06919 K06919 : putative DNA primase/helicase no pathways 59 3

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0000166 nucleotide binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0006260 DNA replication
GO:0003678 DNA helicase activity
GO:0003677 DNA binding
GO:0008270 zinc ion binding
GO:0019079 viral genome replication
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0016032 viral process

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