phrog_4218 is made of 33 protein sequences and is annotated as "anaerobic ribonucleoside reductase large subunit"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
356.48 571 328


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_012740_p57 YP_002922129.1 anaerobic NTP reductase large subunit NC_012740 Escherichia phage JSE Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Krischvirus.
NC_023693_p194 YP_009012525.1 Phi92_gp192 NC_023693 Enterobacteria phage phi92 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_028895_p92 YP_009207557.1 hypothetical protein NC_028895 Vibrio phage phi 3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Ermolyevavirinae; Jesfedecavirus; Vibrio virus phi3.
KY883654_p56 ASV43425.1 ribonucleotide reductase of class III (anaerobic), large subunit KY883654 Vibrio phage JSF10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Demerecviridae; Ermolyevavirinae; Jesfedecavirus; Vibrio virus JSF10.
KU522583_p201 AMM43527.1 putative class III anaerobic ribunucleotide reductase KU522583 Enterobacteria phage ECGD1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
KY554773_p105 ARM67140.1 anaerobic ribonucleoside triphosphate reductase KY554773 Lactococcus phage AM8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554770_p105 ARM66587.1 anaerobic ribonucleoside triphosphate reductase KY554770 Lactococcus phage AM3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554776_p106 ARQ95685.1 anaerobic ribonucleoside triphosphate reductase KY554776 Lactococcus phage AM12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554775_p105 ARM67497.1 anaerobic ribonucleoside triphosphate reductase KY554775 Lactococcus phage AM11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554774_p106 ARM67319.1 anaerobic ribonucleoside triphosphate reductase KY554774 Lactococcus phage AM9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554777_p110 ARM67680.1 ribonucleoside triphosphate reductase KY554777 Lactococcus phage LW81 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554768_p106 ARM66233.1 anaerobic ribonucleoside triphosphate reductase KY554768 Lactococcus phage AM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554769_p105 ARM66410.1 anaerobic ribonucleoside triphosphate reductase KY554769 Lactococcus phage AM2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_024134_p107 YP_009031016.1 anaerobic ribonucleoside triphosphate reductase NC_024134 Escherichia phage FFH2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Vequintavirus.
NC_028248_p165 YP_009177555.1 anaerobic ribonucleoside-triphosphate reductase [Escherichia phage rv5] NC_028248 Escherichia phage slur16 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Vequintavirus; Escherichia virus slur16.
NC_027404_p75 YP_009153678.1 anaerobic NTP reductase large subunit NC_027404 Yersinia phage PST Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
NC_021073_p9 YP_007877982.1 anaerobic ribonucleoside triphosphate reductase NC_021073 Vibrio phage henriette 12B8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
NC_019517_p108 YP_007006279.1 anaerobic ribonucleoside-triphosphate reductase NC_019517 Escherichia phage FV3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Vequintavirinae; Vequintavirus.
NC_031090_p247 YP_009289208.1 ribonucleotide reductase of class III (anaerobic) large subunit NC_031090 Shigella phage SHSML-52-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Mosigvirus; Shigella virus SHSML521.
NC_031047_p118 YP_009284113.1 putative anaerobic ribonucleoside-triphosphate reductase NC_031047 Escherichia phage HY03 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus; Escherichia virus HY03.
MG646672_p37 AUM59513.1 anaerobic NDP reductase MG646672 Salmonella phage BPS17L1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; Salmonella virus BPS17L1.
NC_029023_p35 YP_009219478.1 oxygen sensitive ribonucleoside-triphosphate reductase NC_029023 Escherichia phage JH2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus.
MG251391_p117 AUE22400.1 ribonucleotide reductase of class III (anaerobic) MG251391 Salmonella virus VSe11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; unclassified Felixounavirus.
MG646671_p93 AUM59440.1 anaerobic NDP reductase MG646671 Salmonella phage BPS17S6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; unclassified Felixounavirus.
NC_031082_p118 YP_009288302.1 putative anaerobic ribonucleoside-triphosphate reductase NC_031082 Escherichia phage vB_EcoM_Alf5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; Escherichia virus Alf5.
KP143762_p13 AJF40543.1 anaerobic nucleoside-diphosphate reductase KP143762 Salmonella phage Mushroom Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; Salmonella virus Mushroom.
KY626162_p73 ARK07318.1 ribonucleotide reductase of class III (anaerobic), large subunit KY626162 Salmonella phage Si3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; Salmonella virus Si3.
NC_027329_p115 YP_009146360.1 oxygen sensitive ribonucleoside-triphosphate reductase NC_027329 Salmonella phage vB_SPuM_SP116 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; Salmonella virus SP116.
NC_027360_p75 YP_009150127.1 hypothetical protein NC_027360 Enterobacteriaphage UAB_Phi87 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus.
MG251392_p117 AUE22529.1 ribonucleotide reductase of class III (anaerobic) MG251392 Salmonella virus VSe102 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; unclassified Felixounavirus.
NC_027369_p100 YP_009151342.1 oxygen sensitive ribonucleoside-triphosphate reductase NC_027369 Escherichia phage EC6 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus.
KY883634_p33 ASV41204.1 ribonucleotide reductase of class III (anaerobic), large subunit KY883634 Vibrio phage JSF5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
MF370225_p110 ASR76773.1 ribonucleotide reductase of class III (anaerobic), large subunit MF370225 Salmonella phage ST11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Ounavirinae; Felixounavirus; unclassified Felixounavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_59 1210 HNH endonuclease DNA, RNA and nucleotide metabolism 14 1.51E-29 19.94
phrog_626 224 anaerobic ribonucleotide reductase small subunit DNA, RNA and nucleotide metabolism 14 1.11E-40 31.08
phrog_487 277 NrdD-like anaerobic ribonucleotide reductase large subunit moron, auxiliary metabolic gene and host takeover 14 2.93E-39 29.65
phrog_655 215 homing endonuclease DNA, RNA and nucleotide metabolism 7 4.64E-20 10.46
phrog_314 390 homing endonuclease DNA, RNA and nucleotide metabolism 4 1.20E-10 1.04
phrog_28742 2 no annotation unknown function 2 0 1000
phrog_8826 12 no annotation unknown function 2 7.91E-11 1.22

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_25611 anaerobic ribonucleoside reductase large subunit DNA, RNA and nucleotide metabolism 96.2 9.4E-05 36-324 / 701-970
phrog_26446 anaerobic ribonucleoside reductase large subunit DNA, RNA and nucleotide metabolism 96.0 0.00015 295-328 / 695-728
phrog_29160 anaerobic ribonucleoside reductase large subunit DNA, RNA and nucleotide metabolism 100.0 8.3E-52 170-327 / 2-155
phrog_487 NrdD-like anaerobic ribonucleotide reductase large subunit moron, auxiliary metabolic gene and host takeover 100.0 9E-142 1-328 / 266-604

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13597.5 Anaerobic ribonucleoside-triphosphate reductase 8.1E-47 15-448 / 158-601
PF11230.7 Protein of unknown function (DUF3029) 1.6E-32 30-451 / 132-463
PF02901.14 Pyruvate formate lyase-like 8.4E-20 32-289 / 319-591
PF01228.20 Glycine radical 7.3E-09 329-429 / 6-107

Annotations of the NCBI proteins of this PHROG


9:anaerobic ribonucleoside triphosphate reductase 4:anaerobic ribonucleoside-triphosphate reductase 4:ribonucleotide reductase of class III (anaerobic), large subunit 3:oxygen sensitive ribonucleoside-triphosphate reductase 3:hypothetical protein 2:anaerobic NDP reductase 2:anaerobic NTP reductase large subunit 2:ribonucleotide reductase of class III (anaerobic) 1:anaerobic nucleoside-diphosphate reductase 1:ribonucleoside triphosphate reductase 1:ribonucleotide reductase of class III (anaerobic) large subunit 1:class III anaerobic ribunucleotide reductase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K00527 nrdD : ribonucleoside-triphosphate reductase [EC:1.17.4.2] ko00230 Purine metabolism
ko00240 Pyrimidine metabolism
553 31

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0006260 DNA replication
GO:0055114 oxidation-reduction process
GO:0008152 metabolic process
GO:0003824 catalytic activity
GO:0016491 oxidoreductase activity
GO:0008998 ribonucleoside-triphosphate reductase activity

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