phrog_4225 is made of 33 protein sequences and is annotated as "endonuclease"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
371.06 433 383


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p135872 no NCBI prot ID no annotation VI_00115 Bacilli_gi_545645907 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p157960 no NCBI prot ID no annotation VI_05306 Bacilli_gi_513803224 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Lactobacillus phage phig1e.
p153516 no NCBI prot ID no annotation VI_04630 Bacilli_gi_418174774_9159_49660 Viruses.
p270140 no NCBI prot ID no annotation VI_01063 Betaproteobacteria_gi_223958736 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p206381 no NCBI prot ID no annotation VI_01247 Clostridia_gi_547831345_16388_52509 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p274452 no NCBI prot ID no annotation VI_07352 Gammaproteobacteria_gi_485452921_5_29473 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p30631 no NCBI prot ID no annotation VI_05486 Bacteroidia_gi_282879960_10239_76617 Viruses.
p296045 no NCBI prot ID no annotation VI_03485 Gammaproteobacteria_gi_558507969 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p166436 no NCBI prot ID no annotation VI_07600 Gammaproteobacteria_gi_375108294 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p290531 no NCBI prot ID no annotation VI_06863 Gammaproteobacteria_gi_422649256 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae.
p137435 no NCBI prot ID no annotation VI_03321 Gammaproteobacteria_gi_556495303_2971089_3013109 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p135957 no NCBI prot ID no annotation VI_04412 Bacilli_gi_163806165_83466_125628 Viruses.
p75873 no NCBI prot ID no annotation VI_09316 Gammaproteobacteria_gi_483400214 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p358861 no NCBI prot ID no annotation VI_05925 Clostridia_gi_544988586 Viruses.
p224132 no NCBI prot ID no annotation VI_10992 Gammaproteobacteria_gi_487566515 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p62177 no NCBI prot ID no annotation VI_08379 Gammaproteobacteria_gi_389708617 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY065466_p2 APD22453.1 type I restriction enzyme related protein KY065466 Streptococcus phage IPP25 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p73385 no NCBI prot ID no annotation VI_02719 Gammaproteobacteria_gi_425089767_2720807_2769840 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p283182 no NCBI prot ID no annotation VI_06886 Gammaproteobacteria_gi_452231150 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p39205 no NCBI prot ID no annotation VI_01014 Bacteroidia_gi_223954434_0_61099 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p289504 no NCBI prot ID no annotation VI_09806 Gammaproteobacteria_gi_520924374 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Peduovirinae.
p80798 no NCBI prot ID no annotation VI_01348 Flavobacteriia_gi_444366862 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p307348 no NCBI prot ID no annotation VI_05195 Bacilli_gi_511751413 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p215418 no NCBI prot ID no annotation VI_04063 unknown_gi_547862516 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p58478 no NCBI prot ID no annotation VI_01170 Clostridia_gi_223667572_323765_376572 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p285273 no NCBI prot ID no annotation VI_05796 Clostridia_gi_419719396 Viruses.
p295957 no NCBI prot ID no annotation VI_11404 Gammaproteobacteria_gi_544866157 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p112940 no NCBI prot ID no annotation VI_02615 Gammaproteobacteria_gi_329124276_813_45072 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p225113 no NCBI prot ID no annotation VI_12183 Gammaproteobacteria_gi_545595213_260_34541 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p130702 no NCBI prot ID no annotation VI_06612 Gammaproteobacteria_gi_260583086 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p349701 no NCBI prot ID no annotation VI_07363 Gammaproteobacteria_gi_417846219 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p423124 no NCBI prot ID no annotation VI_06680 Gammaproteobacteria_gi_307254298 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p238679 no NCBI prot ID no annotation VI_06415 Gammaproteobacteria_gi_145629787 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_87 993 metallo-protease other 5 1.14E-10 1.06
phrog_20996 4 no annotation unknown function 4 0 1000
phrog_13333 7 no annotation unknown function 4 3.00E-20 10.64
phrog_7986 14 no annotation unknown function 3 2.18E-14 4.78
phrog_20886 4 no annotation unknown function 2 1.31E-12 3.01
phrog_13139 7 no annotation unknown function 2 1.14E-11 2.06

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_14719 no annotation unknown function 93.8 0.0066 17-131 / 18-146
phrog_16674 DNA methyltransferase other 96.2 9E-05 2-125 / 3-117
phrog_16694 no annotation unknown function 91.9 0.027 22-130 / 93-233
phrog_17239 no annotation unknown function 96.8 9.7E-06 41-166 / 47-166

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF13588.5 Type I restriction enzyme R protein N terminus (HSDR_N) 5E-08 40-138 / 2-98
PF04313.13 Type I restriction enzyme R protein N terminus (HSDR_N) 3.8E-06 62-137 / 145-230

Annotations of the NCBI proteins of this PHROG


1:type I restriction enzyme related protein

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K07504 K07504 : predicted type IV restriction endonuclease no pathways 565 33

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003677 DNA binding
GO:0006304 DNA modification
GO:0004519 endonuclease activity

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