phrog_4278 is made of 32 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
115.34 202 103


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p442172 no NCBI prot ID no annotation VI_12252 Halobacteria_gi_448564640 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p443490 no NCBI prot ID no annotation VI_12222 Halobacteria_gi_448356238 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p440035 no NCBI prot ID no annotation VI_12255 Halobacteria_gi_448598063 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p439666 no NCBI prot ID no annotation VI_12223 Halobacteria_gi_448356977 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p442049 no NCBI prot ID no annotation VI_12273 Halobacteria_gi_448735791 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p442346 no NCBI prot ID no annotation VI_12262 Halobacteria_gi_448677191 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p443300 no NCBI prot ID no annotation VI_12215 Halobacteria_gi_448316119 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p439594 no NCBI prot ID no annotation VI_12238 Halobacteria_gi_448421045 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p443330 no NCBI prot ID no annotation VI_12245 Halobacteria_gi_448495353 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p439518 no NCBI prot ID no annotation VI_12235 Halobacteria_gi_448404314 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p442096 no NCBI prot ID no annotation VI_12218 Halobacteria_gi_448349506 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1; Halogeometricum pleomorphic virus 1.
p48299 no NCBI prot ID no annotation VI_12208 Halobacteria_gi_448294712_6476_64495 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_021340_p82 YP_008060391.1 hypothetical protein NC_021340 Halovirus HHTV-2 Viruses; unclassified viruses; unclassified DNA viruses; unclassified archaeal dsDNA viruses; Haloviruses.
p335240 no NCBI prot ID no annotation VI_12241 Halobacteria_gi_448460196_205347_227019 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p57735 no NCBI prot ID no annotation VI_12271 Halobacteria_gi_448728133_100599_153663 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p279334 no NCBI prot ID no annotation VI_12198 Halobacteria_gi_543936266 Viruses.
p89174 no NCBI prot ID no annotation VI_12219 Halobacteria_gi_448349957 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p57733 no NCBI prot ID no annotation VI_12271 Halobacteria_gi_448728133_100599_153663 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p351489 no NCBI prot ID no annotation VI_12216 Halobacteria_gi_448330764_14227_33803 Viruses.
p341840 no NCBI prot ID no annotation VI_03991 Halobacteria_gi_336252096_3610642_3631645 Viruses.
p362802 no NCBI prot ID no annotation VI_12234 Halobacteria_gi_448386223_0_18400 Viruses.
p418081 no NCBI prot ID no annotation VI_03976 Halobacteria_gi_161561737 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus; Natrialba phage PhiCh1.
p367377 no NCBI prot ID no annotation VI_12217 Halobacteria_gi_448345507_100317_118155 Viruses.
CP003412_p3 AFO55990.1 transcriptional regulator PadR family protein CP003412 Natrinema SNJ2 provirus Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae.
p70191 no NCBI prot ID no annotation VI_12256 Halobacteria_gi_448610561 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p88557 no NCBI prot ID no annotation VI_12254 Halobacteria_gi_448592111 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_004084_p57 NP_665974.1 hypothetical protein NC_004084 Natrialba phage PhiCh1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus.
p47367 no NCBI prot ID no annotation VI_03977 Halobacteria_gi_289594273 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus; Natrialba phage PhiCh1.
p48066 no NCBI prot ID no annotation VI_12205 Halobacteria_gi_448285003 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Myohalovirus; unclassified Myohalovirus; Natrialba phage PhiCh1.
NC_017090_p1 YP_005454295.1 ORF1 NC_017090 Halogeometricum pleomorphic virus 1 Viruses; Monodnaviria; Trapavirae; Saleviricota; Huolimaviricetes; Haloruvirales; Pleolipoviridae; Betapleolipovirus; Betapleolipovirus HGPV1.
p186707 no NCBI prot ID no annotation VI_06215 Cyanobacteria_gi_553739909 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
NC_008695_p21 YP_919048.1 hypothetical protein NC_008695 Archaeal BJ1 virus Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3232 45 no annotation unknown function 12 6.37E-48 38.32
phrog_21306 4 no annotation unknown function 3 2.42E-18 8.74
phrog_24252 3 HNH endonuclease DNA, RNA and nucleotide metabolism 3 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11195 no annotation unknown function 95.9 0.00023 33-85 / 38-92
phrog_1345 MotA-like activator of middle period transcription transcription regulation 92.9 0.014 10-90 / 14-84
phrog_13512 transcriptional regulator transcription regulation 94.8 0.0021 10-88 / 2-85
phrog_2440 transcriptional regulator transcription regulation 96.0 0.00015 13-89 / 10-78
phrog_25401 DNA binding protein DNA, RNA and nucleotide metabolism 95.8 0.00027 19-92 / 18-91
phrog_3502 no annotation unknown function 94.8 0.0021 10-72 / 3-65
phrog_38489 replication terminator DNA, RNA and nucleotide metabolism 93.6 0.0082 13-66 / 13-73
phrog_4054 no annotation unknown function 92.7 0.016 55-90 / 31-66
phrog_900 no annotation unknown function 96.4 5E-05 9-89 / 1-87
phrog_9665 transcriptional regulator transcription regulation 94.8 0.0021 9-93 / 28-116

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF03965.15 Penicillinase repressor 1.6E-07 66-136 / 2-70
PF10007.8 Uncharacterized protein conserved in archaea (DUF2250) 6.9E-07 64-122 / 5-56
PF11313.7 Protein of unknown function (DUF3116) 7.8E-07 87-142 / 21-81
PF14557.5 Putative AphA-like transcriptional regulator 1.7E-06 63-143 / 4-90
PF14277.5 Domain of unknown function (DUF4364) 1.8E-06 70-141 / 3-71
PF04492.12 Bacteriophage replication protein O 1.9E-06 63-132 / 23-92
PF05584.10 Sulfolobus plasmid regulatory protein 4.8E-06 65-122 / 4-52
PF14947.5 Winged helix-turn-helix 6E-06 69-141 / 4-69
PF01475.18 Ferric uptake regulator family 7.5E-06 63-134 / 3-73
PF03551.13 Transcriptional regulator PadR-like family 7.9E-06 87-138 / 15-70
PF13601.5 Winged helix DNA-binding domain 8.4E-06 70-140 / 3-69
PF02334.15 Replication terminator protein 9.2E-06 100-146 / 52-106
PF02319.19 E2F/DP family winged-helix DNA-binding domain 9.4E-06 66-122 / 6-57
PF04079.15 Segregation and condensation complex subunit ScpB 9.6E-06 62-140 / 78-149
PF07106.12 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) 1.5E-05 69-126 / 3-56
PF02002.16 TFIIE alpha subunit 1.6E-05 68-141 / 13-82
PF04358.12 DsrC like protein 1.7E-05 62-122 / 34-95
PF09824.8 ArsR transcriptional regulator 1.7E-05 66-121 / 16-61
PF14394.5 Domain of unknown function (DUF4423) 1.7E-05 66-137 / 20-86
PF08784.10 Replication protein A C terminal 1.8E-05 64-122 / 37-95
PF16221.4 winged helix-turn-helix 1.8E-05 68-120 / 32-78
PF08221.10 RNA polymerase III subunit RPC82 helix-turn-helix domain 1.8E-05 65-121 / 11-60
PF01978.18 Sugar-specific transcriptional regulator TrmB 1.8E-05 64-123 / 5-57
PF05158.11 RNA polymerase Rpc34 subunit 2.1E-05 63-123 / 88-143
PF09857.8 Putative toxin of bacterial toxin-antitoxin pair 2.3E-05 64-142 / 2-79
PF13463.5 Winged helix DNA-binding domain 2.3E-05 67-122 / 3-51
PF01090.18 Ribosomal protein S19e 2.4E-05 68-143 / 52-135
PF10711.8 Hypothetical protein (DUF2513) 2.6E-05 70-143 / 8-85
PF02295.16 Adenosine deaminase z-alpha domain 2.8E-05 67-122 / 4-53
PF01638.16 HxlR-like helix-turn-helix 2.9E-05 68-141 / 6-75
PF01726.15 LexA DNA binding domain 3E-05 66-123 / 5-61
PF09639.9 YjcQ protein 3.5E-05 87-142 / 17-82
PF05732.10 Firmicute plasmid replication protein (RepL) 3.6E-05 63-122 / 50-109
PF06163.10 Bacterial protein of unknown function (DUF977) 3.9E-05 65-123 / 10-61
PF13034.5 Protein of unknown function (DUF3895) 4.6E-05 66-123 / 2-68
PF09012.9 FeoC like transcriptional regulator 5E-05 87-124 / 15-50
PF09202.10 Rio2, N-terminal 5E-05 65-138 / 4-72
PF12793.6 Sugar transport-related sRNA regulator N-term 5.4E-05 87-140 / 19-72
PF09114.9 Transcription factor MotA, activation domain 7.1E-05 63-144 / 12-82
PF09904.8 Winged helix-turn helix 7.1E-05 68-121 / 8-54
PF04182.11 B-block binding subunit of TFIIIC 7.9E-05 68-123 / 3-53
PF03428.12 Replication protein C N-terminal domain 8.3E-05 59-123 / 35-106
PF08222.10 CodY helix-turn-helix domain 9.4E-05 87-122 / 5-38
PF01047.21 MarR family 9.6E-05 68-123 / 4-52
PF07848.11 PaaX-like protein 0.00012 87-133 / 21-67
PF03444.14 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 0.00015 66-137 / 3-71
PF01316.20 Arginine repressor, DNA binding domain 0.00029 67-124 / 5-57
PF01022.19 Bacterial regulatory protein, arsR family 0.0003 70-118 / 5-46
PF13412.5 Winged helix-turn-helix DNA-binding 0.00031 87-118 / 18-47
PF13730.5 Helix-turn-helix domain 0.00035 65-118 / 3-52
PF10771.8 Winged helix-turn-helix domain (DUF2582) 0.00038 65-124 / 6-58
PF09339.9 IclR helix-turn-helix domain 0.00038 87-121 / 19-51
PF08461.9 Ribonuclease R winged-helix domain 0.00041 87-122 / 13-51
PF12802.6 MarR family 0.0004 65-122 / 3-55
PF04703.11 FaeA-like protein 0.00052 71-122 / 4-48
PF16365.4 Ethanolamine utilization protein EutK C-terminus 0.00063 87-121 / 18-50
PF12840.6 Helix-turn-helix domain 0.00065 66-122 / 7-54
PF01325.18 Iron dependent repressor, N-terminal DNA binding domain 0.00082 87-122 / 22-55
PF05331.10 Protein of unknown function (DUF742) 0.001 63-123 / 37-88
PF02082.19 Transcriptional regulator 0.0011 87-122 / 25-58
PF08220.11 DeoR-like helix-turn-helix domain 0.0014 87-122 / 15-48
PF06969.15 HemN C-terminal domain 0.0017 87-121 / 21-54
PF01418.16 Helix-turn-helix domain, rpiR family 0.0019 65-122 / 14-68
PF03297.14 S25 ribosomal protein 0.002 87-121 / 57-89
PF00392.20 Bacterial regulatory proteins, gntR family 0.0022 87-122 / 24-58
PF16864.4 Dimerisation domain 0.0022 68-121 / 19-65
PF14502.5 Helix-turn-helix domain 0.0025 87-122 / 7-40
PF11972.7 HTH DNA binding domain 0.0025 87-119 / 14-41
PF15977.4 Winged helix-turn-helix DNA binding 0.0031 87-122 / 24-57
PF08679.10 Dissimilatory sulfite reductase D (DsrD) 0.0036 70-132 / 3-60
PF07183.10 Protein of unknown function (DUF1403) 0.0036 68-122 / 275-320
PF08279.11 HTH domain 0.0048 87-116 / 16-43
PF13545.5 Crp-like helix-turn-helix domain 0.0057 87-121 / 28-60
PF02650.13 WhiA C-terminal HTH domain 0.0062 65-114 / 38-82
PF14338.5 Mrr N-terminal domain 0.0071 100-139 / 49-84

Annotations of the NCBI proteins of this PHROG


3:hypothetical protein 1:transcriptional regulator PadR family protein 1:protein of an unannotated phage

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0045892 negative regulation of transcription, DNA-templated
GO:0005667 transcription factor complex
GO:0007131 reciprocal meiotic recombination
GO:0004674 protein serine/threonine kinase activity
GO:0009289 pilus
GO:0005622 intracellular
GO:0006260 DNA replication
GO:0006383 transcription by RNA polymerase III
GO:0003677 DNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity
GO:0006468 protein phosphorylation
GO:0006274 DNA replication termination
GO:0005840 ribosome
GO:0003700 DNA binding transcription factor activity
GO:0004252 serine-type endopeptidase activity
GO:0006525 arginine metabolic process
GO:0006412 translation
GO:0051304 chromosome separation
GO:0006355 regulation of transcription, DNA-templated
GO:0003735 structural constituent of ribosome
GO:0003723 RNA binding
GO:0006508 proteolysis
GO:0005666 DNA-directed RNA polymerase III complex
GO:0005524 ATP binding
GO:0006276 plasmid maintenance

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