phrog_4409 is made of 31 protein sequences and is annotated as "guanylate kinase"
Functional category: other


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
298.39 328 304


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_024122_p107 YP_009030429.1 hypothetical protein NC_024122 Salmonella phage vB_SalM_SJ3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
MG383452_p193 ATW66951.1 hypothetical protein MG383452 Escherichia phage FEC14 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
NC_019530_p157 YP_007008137.1 hypothetical protein NC_019530 Salmonella phage Sh19 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
MG973030_p165 AVO23008.1 hypothetical protein MG973030 Erwinia phage vB_EamM-Bue1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
NC_019452_p193 YP_007002833.1 hypothetical protein NC_019452 Escherichia phage PhaxI Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_031045_p29 YP_009283802.1 hypothetical protein NC_031045 Salmonella phage GG32 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_022343_p80 YP_008532031.1 hypothetical protein NC_022343 Klebsiella phage 0507-KN2-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus.
KY630163_p130 ARB06416.1 hypothetical protein KY630163 Salmonella phage S8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
NC_015296_p194 YP_004327565.1 putative uncharacterised protein NC_015296 Salmonella phage ViI Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
KY914485_p37 ARK07856.1 hypothetical protein KY914485 Aeromonas phage phiA8-29 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
KX147096_p79 ANM47188.1 hypothetical protein KX147096 Serratia phage vB_Sru_IME250 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Serratia virus IME250.
MG428990_p14 AUG87720.1 hypothetical protein MG428990 Klebsiella phage Menlow Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Klebsiella virus Menlow.
KX171211_p171 ANT44630.1 hypothetical protein KX171211 Salmonella phage vB_SenM-2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
MF285619_p13 ASZ78779.1 hypothetical protein MF285619 Serratia phage 2050H1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; unclassified Ackermannviridae.
KY942057_p181 ASD51567.1 putative homing endonuclease F-LimXI KY942057 Dickeya phage XF4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Limestonevirus; unclassified Limestonevirus.
NC_013693_p200 YP_003358687.1 hypothetical protein NC_013693 Shigella phage Ag3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Agtrevirus.
MF001362_p187 ASZ77734.1 hypothetical protein MF001362 Salmonella phage SP1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
MG428991_p13 AUG87934.1 hypothetical protein MG428991 Klebsiella phage May Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Taipeivirus; Klebsiella virus May.
NC_016073_p186 YP_004895357.1 hypothetical protein NC_016073 Salmonella phage SFP10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_019910_p186 YP_007236281.1 hypothetical protein NC_019910 Salmonella phage SKML-39 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Aglimvirinae; Agtrevirus.
MG428992_p16 AUG88151.1 hypothetical protein MG428992 Salmonella phage Mutine Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
NC_023856_p129 YP_009021375.1 hypothetical protein NC_023856 Salmonella phage vB_SalM_SJ2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
NC_020083_p11 YP_007348990.1 hypothetical protein NC_020083 Serratia phage phiMAM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae.
NC_016570_p189 YP_004957892.1 hypothetical protein NC_016570 Escherichia virus CBA120 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_031128_p139 YP_009293387.1 hypothetical protein NC_031128 Salmonella phage vB_SalM_PM10 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
KY787213_p54 ARM69891.1 hypothetical protein KY787213 Salmonella phage BSP101 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus; unclassified Kuttervirus.
NC_025446_p95 YP_009101491.1 hypothetical protein NC_025446 Escherichia phage ECML-4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
NC_027119_p179 YP_009140356.1 hypothetical protein NC_027119 Salmonella phage Det7 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae; Cvivirinae; Kuttervirus.
NC_027340_p141 YP_009147653.1 hypothetical protein NC_027340 Erwinia phage phiEa2809 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Ackermannviridae.
NC_022768_p16 YP_008770843.1 hypothetical protein NC_022768 Salmonella phage Maynard Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.
NC_022772_p16 YP_008771634.1 hypothetical protein NC_022772 Salmonella phage Marshall Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Viunavirus.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_3911 36 no annotation unknown function 26 4.93E-108 98.43
phrog_4514 30 no annotation unknown function 23 4.48E-97 87.47
phrog_3271 44 no annotation unknown function 4 1.43E-15 5.97
phrog_4163 33 no annotation unknown function 3 8.34E-13 3.2
phrog_19446 4 homing endonuclease DNA, RNA and nucleotide metabolism 2 1.25E-12 3.03

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_15209 endonuclease DNA, RNA and nucleotide metabolism 100.0 1.5E-78 4-304 / 204-497
phrog_31701 no annotation unknown function 90.8 0.046 1-18 / 5-22
phrog_761 thymidylate kinase other 92.3 0.021 1-52 / 1-50
phrog_800 terminase small subunit head and packaging 95.2 0.001 1-152 / 7-139

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF00625.20 Guanylate kinase 1.2E-09 3-28 / 1-26
PF01121.19 Dephospho-CoA kinase 2.1E-08 5-46 / 1-36
PF00406.21 Adenylate kinase 3.7E-08 9-46 / 1-32
PF13671.5 AAA domain 4.5E-08 6-28 / 1-23
PF08433.9 Chromatin associated protein KTI12 5.7E-08 4-28 / 1-25
PF01745.15 Isopentenyl transferase 6.2E-08 4-44 / 1-35
PF06414.11 Zeta toxin 7.2E-08 3-28 / 13-38
PF01591.17 6-phosphofructo-2-kinase 1E-07 2-28 / 7-33
PF00485.17 Phosphoribulokinase / Uridine kinase family 1.4E-07 6-29 / 1-24
PF13238.5 AAA domain 1.4E-07 7-28 / 1-22
PF07931.11 Chloramphenicol phosphotransferase-like protein 1.8E-07 4-28 / 1-25
PF13189.5 Cytidylate kinase-like family 3.3E-07 6-28 / 1-23
PF01712.18 Deoxynucleoside kinase 4.6E-07 7-28 / 1-22
PF13207.5 AAA domain 5.9E-07 10-46 / 1-31
PF02978.18 Signal peptide binding domain 1.3E-06 242-270 / 1-29
PF01583.19 Adenylylsulphate kinase 1.8E-06 4-28 / 2-26
PF03976.13 Polyphosphate kinase 2 (PPK2) 4.3E-06 2-29 / 26-53
PF02224.17 Cytidylate kinase 9.6E-06 7-45 / 1-33
PF13521.5 AAA domain 2E-05 6-28 / 1-23
PF08303.10 tRNA ligase kinase domain 2.6E-05 6-28 / 1-23
PF01202.21 Shikimate kinase 3.4E-05 13-46 / 1-28
PF03668.14 P-loop ATPase protein family 4.3E-05 4-26 / 1-23
PF02223.16 Thymidylate kinase 0.0001 9-28 / 1-20
PF13476.5 AAA domain 0.0002 5-28 / 21-44
PF13173.5 AAA domain 0.00023 4-27 / 2-25
PF00910.21 RNA helicase 0.00026 7-28 / 1-22
PF03266.14 NTPase 0.00026 7-28 / 2-23
PF10649.8 Protein of unknown function (DUF2478) 0.00027 8-29 / 2-23
PF04275.13 Phosphomevalonate kinase 0.00028 9-28 / 1-20
PF05729.11 NACHT domain 0.00031 6-28 / 2-24
PF13304.5 AAA domain, putative AbiEii toxin, Type IV TA system 0.00032 6-24 / 1-19
PF05272.10 Virulence-associated protein E 0.00035 4-28 / 59-83
PF03215.14 Rad17 cell cycle checkpoint protein 0.00039 4-28 / 45-69
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.00042 3-28 / 3-28
PF13401.5 AAA domain 0.00044 3-28 / 4-29
PF00308.17 Bacterial dnaA protein 0.00048 4-28 / 33-57
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.00053 6-28 / 2-24
PF01637.17 ATPase domain predominantly from Archaea 0.00054 4-28 / 20-44
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 0.00055 3-28 / 44-69
PF04665.11 Poxvirus A32 protein 0.00055 3-28 / 12-37
PF00265.17 Thymidine kinase 0.00064 5-28 / 2-25
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.00066 7-28 / 1-22
PF16813.4 CRISPR-associated protein Csn2 subfamily St 0.00067 4-28 / 15-39
PF06431.10 Polyomavirus large T antigen C-terminus 0.00071 3-28 / 154-179
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.00075 7-27 / 1-21
PF05621.10 Bacterial TniB protein 0.00076 5-28 / 39-62
PF13191.5 AAA ATPase domain 0.00077 5-28 / 25-48
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.00079 3-28 / 13-38
PF04851.14 Type III restriction enzyme, res subunit 0.00083 3-28 / 22-47
PF07693.13 KAP family P-loop domain 0.00085 2-28 / 29-55
PF07728.13 AAA domain (dynein-related subfamily) 0.00086 7-28 / 2-23
PF07475.11 HPr Serine kinase C-terminal domain 0.00086 4-27 / 14-37
PF05673.12 Protein of unknown function (DUF815) 0.00091 4-28 / 54-78
PF12775.6 P-loop containing dynein motor region D3 0.00092 4-28 / 33-57
PF09820.8 Predicted AAA-ATPase 0.00095 4-28 / 31-55
PF01926.22 50S ribosome-binding GTPase 0.001 7-27 / 2-22
PF00158.25 Sigma-54 interaction domain 0.001 3-28 / 21-46
PF02492.18 CobW/HypB/UreG, nucleotide-binding domain 0.0011 6-26 / 2-22
PF01695.16 IstB-like ATP binding protein 0.0011 3-28 / 47-72
PF13177.5 DNA polymerase III, delta subunit 0.0012 4-28 / 19-43
PF11602.7 ATPase P4 of dsRNA bacteriophage phi-12 0.0013 4-28 / 122-146
PF14532.5 Sigma-54 interaction domain 0.0013 4-28 / 21-45
PF05707.11 Zonular occludens toxin (Zot) 0.0014 6-24 / 2-20
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 0.0014 4-28 / 32-56
PF03969.15 AFG1-like ATPase 0.0014 3-28 / 66-91
PF07726.10 ATPase family associated with various cellular activities (AAA) 0.0015 7-28 / 2-23
PF00448.21 SRP54-type protein, GTPase domain 0.0015 5-28 / 2-25
PF01443.17 Viral (Superfamily 1) RNA helicase 0.0015 7-27 / 1-20
PF09848.8 Uncharacterized conserved protein (DUF2075) 0.0015 5-28 / 2-25
PF14516.5 AAA-like domain 0.0016 3-28 / 29-54
PF13479.5 AAA domain 0.0016 4-26 / 2-24
PF00931.21 NB-ARC domain 0.0018 4-28 / 20-44
PF13166.5 AAA domain 0.0018 3-28 / 17-42
PF06745.12 KaiC 0.0018 3-28 / 18-43
PF13481.5 AAA domain 0.0019 4-28 / 28-52
PF00493.22 MCM2/3/5 family 0.002 4-28 / 57-81
PF00437.19 Type II/IV secretion system protein 0.002 4-28 / 130-154
PF03796.14 DnaB-like helicase C terminal domain 0.0021 3-28 / 18-43
PF01078.20 Magnesium chelatase, subunit ChlI 0.0021 4-28 / 22-46
PF02562.15 PhoH-like protein 0.0022 4-27 / 19-42
PF00519.16 Papillomavirus helicase 0.0022 3-28 / 261-286
PF10443.8 RNA12 protein 0.0023 4-28 / 17-42
PF00350.22 Dynamin family 0.0024 7-27 / 1-21
PF09439.9 Signal recognition particle receptor beta subunit 0.0025 4-27 / 3-26
PF10662.8 Ethanolamine utilisation - propanediol utilisation 0.0026 5-26 / 2-23
PF01580.17 FtsK/SpoIIIE family 0.0026 4-28 / 38-62
PF10923.7 P-loop Domain of unknown function (DUF2791) 0.0026 3-29 / 48-74
PF03205.13 Molybdopterin guanine dinucleotide synthesis protein B 0.0026 6-28 / 1-23
PF02456.14 Adenovirus IVa2 protein 0.0026 6-28 / 82-106
PF07724.13 AAA domain (Cdc48 subfamily) 0.0028 4-28 / 3-27
PF13245.5 AAA domain 0.0029 4-28 / 11-35
PF12780.6 P-loop containing dynein motor region D4 0.003 4-28 / 31-55
PF04317.11 YcjX-like family, DUF463 0.0033 6-29 / 2-25
PF13175.5 AAA ATPase domain 0.0035 6-28 / 24-46
PF01057.16 Parvovirus non-structural protein NS1 0.0036 4-28 / 118-142
PF08423.10 Rad51 0.0037 3-28 / 36-61
PF07652.13 Flavivirus DEAD domain 0.0037 3-27 / 3-28
PF00488.20 MutS domain V 0.0037 7-28 / 1-22
PF04310.11 MukB N-terminal 0.0038 5-28 / 27-50
PF08298.10 PrkA AAA domain 0.004 4-28 / 85-109
PF09818.8 Predicted ATPase of the ABC class 0.0041 3-25 / 247-268
PF00154.20 recA bacterial DNA recombination protein 0.0042 3-28 / 51-76
PF00693.17 Thymidine kinase from herpesvirus 0.0044 130-153 / 149-171
PF10236.8 Mitochondrial ribosomal death-associated protein 3 0.0044 3-28 / 23-48
PF01935.16 Domain of unknown function DUF87 0.0046 4-28 / 25-49
PF06309.10 Torsin 0.0047 4-28 / 52-76
PF07088.10 GvpD gas vesicle protein 0.0048 3-28 / 9-34
PF00071.21 Ras family 0.005 7-27 / 2-22
PF17213.2 Hydin Adenylate kinase-like domain 0.005 7-45 / 2-34
PF13604.5 AAA domain 0.0052 7-27 / 19-40
PF13654.5 AAA domain 0.0053 4-28 / 24-48
PF04548.15 AIG1 family 0.006 6-27 / 2-23
PF06068.12 TIP49 C-terminus 0.0064 4-28 / 50-74
PF03029.16 Conserved hypothetical ATP binding protein 0.0065 9-28 / 1-20
PF13514.5 AAA domain 0.0065 3-28 / 25-50
PF03308.15 ArgK protein 0.0069 3-28 / 28-53
PF02421.17 Ferrous iron transport protein B 0.007 7-27 / 2-22
PF04670.11 Gtr1/RagA G protein conserved region 0.0073 7-27 / 2-22
PF10412.8 Type IV secretion-system coupling protein DNA-binding domain 0.0073 5-28 / 16-39
PF05127.13 Helicase 0.0077 8-28 / 1-21
PF05970.13 PIF1-like helicase 0.0077 3-29 / 21-47
PF00025.20 ADP-ribosylation factor family 0.0084 3-27 / 13-37

Annotations of the NCBI proteins of this PHROG


30:hypothetical protein 1:homing endonuclease F-LimXI

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0003924 GTPase activity
GO:0030983 mismatched DNA binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0008152 metabolic process
GO:0006109 regulation of carbohydrate metabolic process
GO:0006298 mismatch repair
GO:0004003 ATP-dependent DNA helicase activity
GO:0009295 nucleoid
GO:0019079 viral genome replication
GO:0008026 ATP-dependent helicase activity
GO:0004631 phosphomevalonate kinase activity
GO:0004672 protein kinase activity
GO:0009058 biosynthetic process
GO:0004140 dephospho-CoA kinase activity
GO:0008134 transcription factor binding
GO:0006576 cellular biogenic amine metabolic process
GO:0005737 cytoplasm
GO:0015937 coenzyme A biosynthetic process
GO:0016740 transferase activity
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0006695 cholesterol biosynthetic process
GO:0004161 dimethylallyltranstransferase activity
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0003678 DNA helicase activity
GO:0006260 DNA replication
GO:0004127 cytidylate kinase activity
GO:0006777 Mo-molybdopterin cofactor biosynthetic process
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0003873 6-phosphofructo-2-kinase activity
GO:0006230 TMP biosynthetic process
GO:0003723 RNA binding
GO:0006281 DNA repair
GO:0003697 single-stranded DNA binding
GO:0030261 chromosome condensation
GO:0004797 thymidine kinase activity
GO:0005525 GTP binding
GO:0000155 phosphorelay sensor kinase activity
GO:0006270 DNA replication initiation
GO:0016887 ATPase activity
GO:0009236 cobalamin biosynthetic process
GO:0043531 ADP binding
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0000160 phosphorelay signal transduction system
GO:0007059 chromosome segregation
GO:0016020 membrane
GO:0003724 RNA helicase activity
GO:0006139 nucleobase-containing compound metabolic process
GO:0019072 viral genome packaging
GO:0051188 cofactor biosynthetic process
GO:0006355 regulation of transcription, DNA-templated
GO:0048500 signal recognition particle
GO:0000166 nucleotide binding
GO:0006000 fructose metabolic process
GO:0000723 telomere maintenance
GO:0003972 RNA ligase (ATP) activity
GO:0004673 protein histidine kinase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0019073 viral DNA genome packaging
GO:0008312 7S RNA binding
GO:0016787 hydrolase activity
GO:0009378 four-way junction helicase activity

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