phrog_4412 is made of 31 protein sequences and is annotated as "exonuclease V"
Functional category: DNA, RNA and nucleotide metabolism


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
777.61 995 767


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p152729 no NCBI prot ID no annotation VI_00586 Bacilli_gi_502174871_1518129_1558706 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p275908 no NCBI prot ID no annotation VI_00516 Bacilli_gi_501007686_0_29277 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p152502 no NCBI prot ID no annotation VI_00585 Bacilli_gi_502168195_1834634_1875220 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p152555 no NCBI prot ID no annotation VI_00610 Bacilli_gi_502432782_1367392_1407978 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554768_p2 ARM66129.1 exodeoxyribonuclease KY554768 Lactococcus phage AM1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_029119_p28 YP_009226704.1 ATP-dependent RecD-like DNA helicase NC_029119 Staphylococcus phage SPbeta-like Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY554773_p2 ARM67037.1 exodeoxyribonuclease KY554773 Lactococcus phage AM8 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554774_p2 ARM67215.1 exodeoxyribonuclease KY554774 Lactococcus phage AM9 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_007581_p62 YP_398492.1 exodeoxyribonuclease V, alpha subunit NC_007581 Clostridium phage c-st Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_023007_p264 YP_008873506.1 hypothetical protein NC_023007 Bacillus phage vB_BanS-Tsamsa Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p125561 no NCBI prot ID no annotation VI_05266 Bacilli_gi_501059894 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY554775_p2 ARM67394.1 exodeoxyribonuclease KY554775 Lactococcus phage AM11 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554772_p2 ARM66855.1 exodeoxyribonuclease KY554772 Lactococcus phage AM5 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p71952 no NCBI prot ID no annotation VI_05747 Clostridia_gi_153883184 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Clostridium phage c-st.
NC_029073_p1 YP_009223708.1 RecD/TrA-like helicase NC_029073 Geobacillus virus E3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_023574_p2 YP_009006880.1 putative exodeoxyribonuclease NC_023574 Lactococcus phage phiL47 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p37819 no NCBI prot ID no annotation VI_04875 Bacilli_gi_420233465 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY554770_p2 ARM66484.1 exodeoxyribonuclease KY554770 Lactococcus phage AM3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_015263_p2 YP_004306162.1 putative exodeoxyribonuclease NC_015263 Lactococcus phage 949 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p4004 no NCBI prot ID no annotation VI_04690 Bacilli_gi_377832687 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
NC_027341_p2 YP_009147659.1 exodeoxyribonuclease NC_027341 Lactococcus phage WRP3 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p45545 no NCBI prot ID no annotation VI_05038 Bacilli_gi_481024571 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY554776_p2 ARQ95581.1 exodeoxyribonuclease KY554776 Lactococcus phage AM12 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554769_p2 ARM66307.1 exodeoxyribonuclease KY554769 Lactococcus phage AM2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY554777_p2 ARM67572.1 RecD/TraA family helicase KY554777 Lactococcus phage LW81 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KT070867_p251 AKQ08566.1 putative viral helicase-like protein KT070867 Bacillus phage PBC2 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_028749_p12 YP_009194062.1 putative RecD/TraA family helicase NC_028749 Brevibacillus phage Sundance Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
KY554771_p2 ARM66661.1 exodeoxyribonuclease KY554771 Lactococcus phage AM4 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p39509 no NCBI prot ID no annotation VI_01268 Clostridia_gi_548093166 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p68094 no NCBI prot ID no annotation VI_05269 Bacilli_gi_501033790 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p7123 no NCBI prot ID no annotation VI_06240 Deltaproteobacteria_gi_544815434 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_8504 13 no annotation unknown function 13 0 1000
phrog_1 5879 integrase integration and excision 13 1.13E-20 11.07
phrog_18421 5 no annotation unknown function 5 0 1000

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_168 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 95.1 0.0013 350-469 / 21-135
phrog_16 DNA helicase DNA, RNA and nucleotide metabolism 90.1 0.063 350-450 / 3-111
phrog_170 PhoH-like phosphate starvation-inducible other 98.0 9.6E-09 349-504 / 32-236
phrog_1967 DNA helicase DNA, RNA and nucleotide metabolism 99.3 6.6E-16 348-519 / 3-304
phrog_25411 no annotation unknown function 99.0 1.2E-13 349-481 / 213-396
phrog_25471 no annotation unknown function 98.8 2.3E-12 349-475 / 2-161
phrog_2765 PhoH-like phosphate starvation-inducible other 95.3 0.00083 351-504 / 252-448
phrog_293 ABC transporter moron, auxiliary metabolic gene and host takeover 93.8 0.0066 354-471 / 24-180
phrog_296 DNA transposition protein integration and excision 91.4 0.036 362-471 / 89-199
phrog_30356 helicase DNA, RNA and nucleotide metabolism 98.8 1.9E-12 361-676 / 15-319
phrog_325 Dda-like helicase DNA, RNA and nucleotide metabolism 100.0 3E-57 347-737 / 3-418
phrog_50 DnaC-like helicase loader DNA, RNA and nucleotide metabolism 93.1 0.012 364-448 / 112-187
phrog_5534 no annotation unknown function 91.3 0.036 365-593 / 28-248
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 95.2 0.001 357-478 / 27-139
phrog_62 DNA helicase DNA, RNA and nucleotide metabolism 91.7 0.03 347-472 / 3-161
phrog_7998 no annotation unknown function 92.0 0.026 365-486 / 39-166

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF14490.5 Helix-hairpin-helix containing domain 2.8E-16 156-246 / 2-91
PF09848.8 Uncharacterized conserved protein (DUF2075) 2.8E-09 351-438 / 2-79
PF13361.5 UvrD-like helicase C-terminal domain 6.8E-09 668-719 / 485-547
PF05970.13 PIF1-like helicase 1.3E-07 349-392 / 21-64
PF07652.13 Flavivirus DEAD domain 2.2E-07 349-467 / 3-141
PF02399.14 Origin of replication binding protein 3E-07 348-466 / 47-194
PF06862.11 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 3.9E-07 337-400 / 1-108
PF00270.28 DEAD/DEAH box helicase 5.5E-07 338-398 / 2-65
PF13538.5 UvrD-like helicase C-terminal domain 7.5E-07 668-715 / 1-47
PF04851.14 Type III restriction enzyme, res subunit 1.3E-06 336-392 / 4-65
PF02562.15 PhoH-like protein 1.9E-06 334-391 / 3-62
PF13872.5 P-loop containing NTP hydrolase pore-1 3.3E-06 334-400 / 34-111
PF13087.5 AAA domain 3.7E-06 669-719 / 214-269
PF14617.5 U3-containing 90S pre-ribosomal complex subunit 4.9E-06 331-400 / 60-140
PF00176.22 SNF2 family N-terminal domain 1.1E-05 425-471 / 154-202
PF04257.13 Exodeoxyribonuclease V, gamma subunit 3.3E-05 668-721 / 619-696
PF00580.20 UvrD/REP helicase N-terminal domain 8.6E-05 338-396 / 3-63
PF13245.5 AAA domain 9.8E-05 347-390 / 8-51
PF07517.13 SecA DEAD-like domain 0.00014 334-399 / 89-152
PF01443.17 Viral (Superfamily 1) RNA helicase 0.00021 671-716 / 160-204
PF13086.5 AAA domain 0.00031 336-398 / 2-67
PF13604.5 AAA domain 0.00044 337-370 / 3-36
PF05127.13 Helicase 0.0006 354-438 / 1-84
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.0013 352-387 / 2-37
PF04466.12 Phage terminase large subunit 0.0047 352-392 / 3-47
PF12340.7 Protein of unknown function (DUF3638) 0.0073 329-400 / 16-87

Annotations of the NCBI proteins of this PHROG


12:exodeoxyribonuclease 2:RecD/TraA family helicase 1:viral helicase-like protein 1:exodeoxyribonuclease V, alpha subunit 1:protein of an unannotated phage 1:ATP-dependent RecD-like DNA helicase 1:RecD/TrA-like helicase

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
K03581 recD : exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] ko03440 Homologous recombination 1494 25

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0008026 ATP-dependent helicase activity
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0016020 membrane
GO:0017038 protein import
GO:0003677 DNA binding
GO:0000723 telomere maintenance
GO:0005634 nucleus
GO:0005524 ATP binding
GO:0009236 cobalamin biosynthetic process
GO:0006281 DNA repair
GO:0003688 DNA replication origin binding
GO:0003676 nucleic acid binding
GO:0003678 DNA helicase activity
GO:0006260 DNA replication
GO:0016787 hydrolase activity

Loading in process