phrog_4494 is made of 30 protein sequences and is annotated as "unknown function"
Functional category: unknown function


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
98.73 131 109


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
p409661 no NCBI prot ID no annotation VI_06907 Gammaproteobacteria_gi_452274727 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p432242 no NCBI prot ID no annotation VI_10360 Gammaproteobacteria_gi_485838995 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; unclassified Lambdavirus.
p158889 no NCBI prot ID no annotation VI_06901 Gammaproteobacteria_gi_452274161 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p424552 no NCBI prot ID no annotation VI_10591 Gammaproteobacteria_gi_486095161 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p423726 no NCBI prot ID no annotation VI_10393 Gammaproteobacteria_gi_485849212 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p95910 no NCBI prot ID no annotation VI_10991 Gammaproteobacteria_gi_487563381 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p424199 no NCBI prot ID no annotation VI_10571 Gammaproteobacteria_gi_486035004 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p416096 no NCBI prot ID no annotation VI_06904 Gammaproteobacteria_gi_452274443 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Nickievirus; unclassified Nickievirus; Salmonella phage SSU5.
p221804 no NCBI prot ID no annotation VI_10431 Gammaproteobacteria_gi_485863404 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Lambdavirus; Escherichia virus HK630; Escherichia phage HK630.
p390324 no NCBI prot ID no annotation VI_10365 Gammaproteobacteria_gi_485839263 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p424038 no NCBI prot ID no annotation VI_10392 Gammaproteobacteria_gi_485848888 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p377738 no NCBI prot ID no annotation VI_10989 Gammaproteobacteria_gi_487563143 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae.
p425469 no NCBI prot ID no annotation VI_10406 Gammaproteobacteria_gi_485852226 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p230252 no NCBI prot ID no annotation VI_08195 Gammaproteobacteria_gi_419365894_0_33810 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; Muvirus.
p114565 no NCBI prot ID no annotation VI_04624 Bacilli_gi_418143142 Viruses.
p210583 no NCBI prot ID no annotation VI_04632 Bacilli_gi_418217724 Viruses.
p401267 no NCBI prot ID no annotation VI_04549 Bacilli_gi_417695265 Viruses; unclassified viruses; unclassified DNA viruses; unclassified dsDNA viruses.
p20232 no NCBI prot ID no annotation VI_03506 Gammaproteobacteria_gi_514965089 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p187054 no NCBI prot ID no annotation VI_04635 Bacilli_gi_418237552 Viruses.
p214190 no NCBI prot ID no annotation VI_04825 Bacilli_gi_419524742 Viruses.
p136109 no NCBI prot ID no annotation VI_04622 Bacilli_gi_418134205 Viruses.
p208211 no NCBI prot ID no annotation VI_04621 Bacilli_gi_418108933 Viruses.
p20313 no NCBI prot ID no annotation VI_03506 Gammaproteobacteria_gi_514965089 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p208362 no NCBI prot ID no annotation VI_04817 Bacilli_gi_419461106 Viruses.
p176000 no NCBI prot ID no annotation VI_04626 Bacilli_gi_418161016 Viruses.
p177778 no NCBI prot ID no annotation VI_05460 Bacilli_gi_452741934 Viruses.
p201353 no NCBI prot ID no annotation VI_04413 Bacilli_gi_163806179 Viruses.
p26786 no NCBI prot ID no annotation VI_00069 Alphaproteobacteria_gi_224580657 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
p26861 no NCBI prot ID no annotation VI_00069 Alphaproteobacteria_gi_224580657 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Myoviridae; unclassified Myoviridae.
p257389 no NCBI prot ID no annotation VI_04414 Bacilli_gi_163806182 Viruses.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_31396 2 no annotation unknown function 2 0 1000
phrog_4140 34 no annotation unknown function 2 2.76E-11 1.68
phrog_13004 8 no annotation unknown function 2 2.58E-13 3.71

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_11108 no annotation unknown function 92.2 0.023 8-102 / 50-137
phrog_11420 DNA binding protein DNA, RNA and nucleotide metabolism 91.4 0.035 3-44 / 11-52
phrog_1157 transposase integration and excision 99.5 4.3E-18 1-105 / 1-96
phrog_125 DNA invertase DNA, RNA and nucleotide metabolism 92.0 0.026 28-101 / 118-186
phrog_12823 no annotation unknown function 94.6 0.0028 10-99 / 21-103
phrog_14025 no annotation unknown function 95.1 0.0012 9-42 / 22-55
phrog_14131 DNA binding protein DNA, RNA and nucleotide metabolism 96.7 1.6E-05 6-103 / 111-204
phrog_141 terminase small subunit head and packaging 91.6 0.032 17-47 / 9-39
phrog_1482 terminase small subunit head and packaging 93.6 0.0078 2-41 / 13-54
phrog_151 transposase integration and excision 97.0 3.2E-06 2-46 / 6-52
phrog_15534 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.3 0.058 18-72 / 40-88
phrog_1553 excisionase integration and excision 90.9 0.044 20-40 / 7-27
phrog_1558 no annotation unknown function 93.0 0.013 17-41 / 117-141
phrog_157 transposase integration and excision 92.0 0.025 23-103 / 1-79
phrog_17819 no annotation unknown function 95.6 0.00047 3-40 / 6-45
phrog_18995 terminase small subunit head and packaging 95.1 0.0012 1-40 / 1-41
phrog_20467 HNH endonuclease DNA, RNA and nucleotide metabolism 94.2 0.0043 3-40 / 56-93
phrog_2308 no annotation unknown function 93.7 0.0073 8-43 / 7-42
phrog_24579 terminase small subunit head and packaging 95.3 0.00083 11-51 / 25-65
phrog_2538 terminase small subunit head and packaging 96.1 0.00011 8-51 / 9-53
phrog_2610 no annotation unknown function 93.7 0.0072 15-102 / 28-143
phrog_26674 no annotation unknown function 90.1 0.063 13-96 / 137-211
phrog_268 no annotation unknown function 93.4 0.0098 14-42 / 13-41
phrog_2727 no annotation unknown function 90.5 0.052 9-42 / 17-50
phrog_27475 no annotation unknown function 99.9 2.8E-30 1-108 / 1-99
phrog_2789 transcriptional regulator transcription regulation 92.1 0.024 2-94 / 12-93
phrog_309 terminase small subunit head and packaging 95.6 0.00048 8-39 / 15-46
phrog_3218 terminase small subunit head and packaging 93.3 0.01 11-51 / 27-67
phrog_323 transcriptional regulator, D5-like transcription regulation 91.3 0.037 7-47 / 55-94
phrog_3470 no annotation unknown function 91.8 0.028 15-78 / 4-71
phrog_3803 RIIB lysis inhibitor lysis 92.1 0.024 8-95 / 6-87
phrog_3855 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.3 0.00088 7-45 / 69-107
phrog_3910 transcriptional regulator transcription regulation 94.0 0.0054 8-39 / 70-101
phrog_3 transcriptional repressor transcription regulation 92.1 0.025 15-41 / 14-40
phrog_409 transcriptional regulator transcription regulation 91.8 0.028 17-39 / 11-32
phrog_4102 terminase small subunit head and packaging 96.1 0.00012 4-82 / 12-75
phrog_4151 DNA binding protein DNA, RNA and nucleotide metabolism 92.6 0.018 10-40 / 13-43
phrog_4646 transposase integration and excision 95.6 0.00048 6-100 / 11-139
phrog_4745 DNA binding protein DNA, RNA and nucleotide metabolism 91.1 0.04 20-43 / 7-30
phrog_4779 transcriptional regulator transcription regulation 92.2 0.022 14-45 / 11-42
phrog_4869 no annotation unknown function 90.7 0.049 11-44 / 4-37
phrog_5301 transcriptional repressor transcription regulation 91.7 0.03 12-100 / 18-80
phrog_534 DNA binding protein DNA, RNA and nucleotide metabolism 94.1 0.0049 19-69 / 27-80
phrog_5497 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.0 0.0015 8-40 / 32-64
phrog_5536 no annotation unknown function 90.0 0.065 5-39 / 9-43
phrog_5735 no annotation unknown function 90.3 0.057 4-39 / 50-85
phrog_5751 terminase large subunit head and packaging 96.0 0.00016 1-42 / 1-43
phrog_597 DNA binding protein DNA, RNA and nucleotide metabolism 91.8 0.029 15-47 / 12-44
phrog_6081 no annotation unknown function 91.3 0.037 1-102 / 1-104
phrog_609 RIIB lysis inhibitor lysis 92.3 0.021 8-46 / 13-52
phrog_6156 endonuclease DNA, RNA and nucleotide metabolism 91.8 0.028 3-44 / 20-67
phrog_664 DNA binding protein DNA, RNA and nucleotide metabolism 96.5 3.4E-05 8-51 / 59-102
phrog_668 HTH DNA binding protein DNA, RNA and nucleotide metabolism 90.9 0.045 14-71 / 33-85
phrog_66 excisionase and transcriptional regulator integration and excision 95.9 0.00025 15-73 / 7-61
phrog_6831 transcriptional regulator transcription regulation 92.4 0.021 8-39 / 6-37
phrog_7061 HTH DNA binding protein DNA, RNA and nucleotide metabolism 95.6 0.00047 3-41 / 29-68
phrog_7067 terminase small subunit head and packaging 92.2 0.023 8-39 / 22-53
phrog_7344 terminase small subunit head and packaging 92.3 0.021 15-39 / 24-48
phrog_7545 HNH endonuclease DNA, RNA and nucleotide metabolism 91.0 0.042 13-46 / 14-47
phrog_756 DNA binding protein DNA, RNA and nucleotide metabolism 94.3 0.0039 1-71 / 1-79
phrog_7847 no annotation unknown function 99.9 6E-28 1-107 / 1-98
phrog_836 late transcriptional activator transcription regulation 94.2 0.0046 14-44 / 106-136
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 93.2 0.012 12-46 / 56-90
phrog_8463 transposase integration and excision 94.0 0.0053 8-104 / 16-126
phrog_8 transcriptional regulator transcription regulation 95.0 0.0014 15-40 / 12-36
phrog_9129 no annotation unknown function 92.1 0.024 13-100 / 81-175
phrog_9759 DNA binding protein DNA, RNA and nucleotide metabolism 92.7 0.017 18-46 / 19-47

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF01710.15 Transposase 1.4E-12 8-113 / 2-102
PF08822.10 Protein of unknown function (DUF1804) 7E-11 8-111 / 2-110
PF04936.11 Protein of unknown function (DUF658) 0.0011 23-50 / 87-114
PF00292.17 'Paired box' domain 1.9E-10 6-51 / 15-60
PF04552.12 Sigma-54, DNA binding domain 3.8E-08 9-111 / 31-155
PF07141.10 Putative bacteriophage terminase small subunit 4.9E-08 4-50 / 7-57
PF07750.10 GcrA cell cycle regulator 8.3E-08 8-50 / 2-45
PF15978.4 Tn7-like transposition protein D 1.4E-07 8-51 / 186-230
PF09607.9 Brinker DNA-binding domain 3.1E-07 7-50 / 4-51
PF12759.6 InsA C-terminal domain 5.9E-07 9-48 / 6-45
PF13011.5 leucine-zipper of insertion element IS481 1.1E-06 7-51 / 6-51
PF06056.11 Putative ATPase subunit of terminase (gpP-like) 2.7E-06 16-50 / 5-39
PF14493.5 Helix-turn-helix domain 2.8E-06 19-51 / 7-39
PF16677.4 DNA-packaging protein gp3 3.1E-06 6-48 / 3-53
PF06627.10 Protein of unknown function (DUF1153) 4.9E-06 6-51 / 27-73
PF02796.14 Helix-turn-helix domain of resolvase 5.6E-06 10-47 / 7-44
PF10668.8 Phage terminase small subunit 7.6E-06 8-50 / 4-48
PF05344.10 Domain of Unknown Function (DUF746) 7.7E-06 20-50 / 8-38
PF13542.5 Helix-turn-helix domain of transposase family ISL3 1.1E-05 8-48 / 11-50
PF10654.8 Protein of unknown function (DUF2481) 1.1E-05 16-47 / 72-103
PF13411.5 MerR HTH family regulatory protein 1.3E-05 26-50 / 2-26
PF13309.5 HTH domain 1.3E-05 8-46 / 19-63
PF13936.5 Helix-turn-helix domain 1.9E-05 11-46 / 7-42
PF12824.6 Mitochondrial ribosomal protein subunit L20 2.1E-05 7-47 / 87-130
PF04218.12 CENP-B N-terminal DNA-binding domain 2.4E-05 9-49 / 7-48
PF01527.19 Transposase 3.4E-05 8-49 / 4-46
PF03333.12 Adhesin biosynthesis transcription regulatory protein 3.2E-05 10-49 / 41-80
PF08765.10 Mor transcription activator family 3.6E-05 17-50 / 66-98
PF16087.4 Domain of unknown function (DUF4817) 4.1E-05 13-51 / 4-51
PF11427.7 Tc3 transposase 4.9E-05 16-49 / 12-45
PF06322.10 Phage NinH protein 5.3E-05 22-50 / 14-42
PF08004.10 Protein of unknown function (DUF1699) 6.4E-05 10-45 / 90-129
PF13613.5 Helix-turn-helix of DDE superfamily endonuclease 7.6E-05 22-49 / 17-44
PF17443.1 Uncharacterized protein pXO2-72 7.8E-05 23-48 / 7-32
PF13518.5 Helix-turn-helix domain 9E-05 23-51 / 10-38
PF02954.18 Bacterial regulatory protein, Fis family 0.00014 23-47 / 15-39
PF10975.7 Protein of unknown function (DUF2802) 0.00013 11-44 / 30-63
PF05331.10 Protein of unknown function (DUF742) 0.00013 10-50 / 40-79
PF01381.21 Helix-turn-helix 0.00015 22-47 / 7-32
PF13384.5 Homeodomain-like domain 0.00016 16-48 / 9-41
PF07638.10 ECF sigma factor 0.00017 10-48 / 135-173
PF13022.5 Helix-turn-helix of insertion element transposase 0.00018 24-47 / 25-48
PF06806.11 Putative excisionase (DUF1233) 0.0002 24-46 / 9-31
PF11112.7 Pyocin activator protein PrtN 0.00021 23-49 / 12-39
PF05225.15 helix-turn-helix, Psq domain 0.00023 22-48 / 14-41
PF07453.12 NUMOD1 domain 0.00025 24-44 / 19-39
PF13551.5 Winged helix-turn helix 0.00027 21-51 / 8-38
PF08535.9 KorB domain 0.00028 23-50 / 2-29
PF00356.20 Bacterial regulatory proteins, lacI family 0.00029 26-47 / 1-22
PF13412.5 Winged helix-turn-helix DNA-binding 0.00031 23-50 / 16-43
PF01371.18 Trp repressor protein 0.00033 20-49 / 44-73
PF00376.22 MerR family regulatory protein 0.00034 27-48 / 2-23
PF13556.5 PucR C-terminal helix-turn-helix domain 0.00035 22-50 / 10-38
PF02319.19 E2F/DP family winged-helix DNA-binding domain 0.00038 23-51 / 22-50
PF13591.5 MerR HTH family regulatory protein 0.0004 25-47 / 1-23
PF05930.11 Prophage CP4-57 regulatory protein (AlpA) 0.00042 24-46 / 3-25
PF07825.10 Excisionase-like protein 0.00043 25-49 / 3-29
PF06413.10 Neugrin 0.00044 7-47 / 9-52
PF16509.4 TrfB plasmid transcriptional repressor 0.00053 18-49 / 25-56
PF08281.11 Sigma-70, region 4 0.00056 21-47 / 23-49
PF07278.10 Protein of unknown function (DUF1441) 0.00062 24-48 / 1-25
PF09035.9 Excisionase from transposon Tn916 0.00064 23-47 / 14-38
PF13413.5 Helix-turn-helix domain 0.00066 22-47 / 7-32
PF10743.8 Regulatory phage protein cox 0.00073 22-49 / 9-36
PF04545.15 Sigma-70, region 4 0.00078 22-47 / 22-47
PF13404.5 AsnC-type helix-turn-helix domain 0.00081 23-47 / 16-40
PF02042.14 RWP-RK domain 0.00088 22-49 / 10-37
PF11242.7 Protein of unknown function (DUF2774) 0.00091 21-49 / 11-39
PF00440.22 Bacterial regulatory proteins, tetR family 0.0011 25-48 / 16-39
PF12728.6 Helix-turn-helix domain 0.0012 25-47 / 2-25
PF06970.10 Replication initiator protein A (RepA) N-terminus 0.0011 26-47 / 53-74
PF12116.7 Stage III sporulation protein D 0.0013 23-47 / 18-42
PF04297.13 Putative helix-turn-helix protein, YlxM / p13 like 0.0013 10-48 / 19-57
PF12964.6 Protein of unknown function (DUF3853) 0.0014 23-49 / 44-70
PF06530.11 Phage antitermination protein Q 0.0014 12-47 / 67-102
PF07900.10 Protein of unknown function (DUF1670) 0.0015 22-106 / 93-177
PF00126.26 Bacterial regulatory helix-turn-helix protein, lysR family 0.0016 23-50 / 10-37
PF07037.10 Putative transcription regulator (DUF1323) 0.0018 26-47 / 2-23
PF00325.19 Bacterial regulatory proteins, crp family 0.002 25-48 / 3-26
PF02001.15 Protein of unknown function DUF134 0.0019 20-48 / 43-71
PF16264.4 SatD family (SatD) 0.0022 8-47 / 150-194
PF07506.10 RepB plasmid partitioning protein 0.0022 18-48 / 15-45
PF07374.10 Protein of unknown function (DUF1492) 0.0023 20-47 / 67-94
PF08222.10 CodY helix-turn-helix domain 0.0024 24-51 / 4-31
PF07471.11 Phage DNA packaging protein Nu1 0.0024 25-47 / 3-25
PF04967.11 HTH DNA binding domain 0.0027 25-48 / 24-47
PF06971.12 Putative DNA-binding protein N-terminus 0.0027 24-45 / 27-48
PF10078.8 Uncharacterized protein conserved in bacteria (DUF2316) 0.0027 22-47 / 21-46
PF01418.16 Helix-turn-helix domain, rpiR family 0.0028 24-49 / 34-59
PF00196.18 Bacterial regulatory proteins, luxR family 0.003 21-49 / 14-42
PF09862.8 Protein of unknown function (DUF2089) 0.0029 14-49 / 39-74
PF12802.6 MarR family 0.0035 25-51 / 22-48
PF07618.10 Protein of unknown function (DUF1580) 0.0036 29-48 / 7-26
PF05043.12 Mga helix-turn-helix domain 0.0048 23-50 / 29-56
PF01022.19 Bacterial regulatory protein, arsR family 0.0051 23-49 / 15-41
PF13443.5 Cro/C1-type HTH DNA-binding domain 0.0058 23-47 / 9-34
PF16221.4 winged helix-turn-helix 0.0059 24-50 / 46-72
PF12793.6 Sugar transport-related sRNA regulator N-term 0.0063 22-52 / 16-46
PF08279.11 HTH domain 0.0068 23-50 / 14-41
PF14549.5 DNA-binding transcriptional regulator Cro 0.0086 23-44 / 9-29
PF09182.9 Bacterial purine repressor, N-terminal 0.0089 23-50 / 19-46
PF09012.9 FeoC like transcriptional regulator 0.0095 23-51 / 13-41
PF15943.4 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT 0.01 25-45 / 9-29

Annotations of the NCBI proteins of this PHROG


no RefSeq proteins in this PHROG (only proteins from VirSorter contigs)

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0005622 intracellular
GO:0005667 transcription factor complex
GO:0045892 negative regulation of transcription, DNA-templated
GO:0016987 sigma factor activity
GO:0006313 transposition, DNA-mediated
GO:0000150 recombinase activity
GO:0003700 DNA binding transcription factor activity
GO:0006310 DNA recombination
GO:0003677 DNA binding
GO:0006355 regulation of transcription, DNA-templated
GO:0005737 cytoplasm
GO:0006352 DNA-templated transcription, initiation
GO:0051775 response to redox state
GO:0019069 viral capsid assembly
GO:0060567 negative regulation of DNA-templated transcription, termination
GO:0005524 ATP binding
GO:0043565 sequence-specific DNA binding
GO:0004803 transposase activity

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