phrog_4581 is made of 30 protein sequences and is annotated as "terminase small subunit"
Functional category: head and packaging


Average length of proteins Number of columns in the MSA Number of conserved columns in the MSA
258.8 563 265


List of all proteins of this PHROG

PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus name Virus taxonomy
NC_030912_p27 YP_009274039.1 ABC transporter ATP-binding protein NC_030912 Gordonia phage McGonagall Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p391854 no NCBI prot ID no annotation VI_04094 Actinobacteria_gi_326385254 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae; Rhodococcus phage RRH1.
p87744 no NCBI prot ID no annotation VI_04107 Actinobacteria_gi_484048409 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p90539 no NCBI prot ID no annotation VI_04116 Actinobacteria_gi_419962223 Viruses.
p40323 no NCBI prot ID no annotation VI_04151 Actinobacteria_gi_484231591 Viruses.
NC_031122_p73 YP_009292464.1 HNH endonuclease NC_031122 Gordonia phage Eyre Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; Eyrevirus; Gordonia virus Eyre.
KY250482_p101 APQ42604.1 putative ATPase KY250482 Corynebacterium phage phi16 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
KY653126_p40 ARM68372.1 hypothetical protein KY653126 Staphylococcus phage IME1354_01 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p92399 no NCBI prot ID no annotation VI_05198 Bacilli_gi_484104960 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p343776 no NCBI prot ID no annotation VI_05468 Bacilli_gi_484032532 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p240654 no NCBI prot ID no annotation VI_05157 Bacilli_gi_511646053 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_019486_p57 YP_007003257.1 HNH endonuclease domain protein NC_019486 Lactobacillus phage LF1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p285537 no NCBI prot ID no annotation VI_04526 Bacilli_gi_336232955 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p176927 no NCBI prot ID no annotation VI_00943 Bacilli_gi_548585805 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p183848 no NCBI prot ID no annotation VI_05441 Bacilli_gi_365822846 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p143676 no NCBI prot ID no annotation VI_04441 Bacilli_gi_199598923 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
MF999224_p34 ATN93894.1 terminase small subunit MF999224 Lactobacillus phage LJ Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p371182 no NCBI prot ID no annotation VI_05193 Bacilli_gi_511751224 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_022757_p59 YP_008767365.1 hypothetical protein NC_022757 Lactobacillus phage PL-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
NC_022756_p63 YP_008767306.1 hypothetical protein NC_022756 Lactobacillus phage J-1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p291191 no NCBI prot ID no annotation VI_05184 Bacilli_gi_511748055 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
NC_011104_p54 YP_002117722.1 small terminase subunit NC_011104 Lactobacillus phage Lrm1 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae.
p224287 no NCBI prot ID no annotation VI_04612 Bacilli_gi_418072794 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p140686 no NCBI prot ID no annotation VI_00453 Bacilli_gi_242364322_195_41921 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p283684 no NCBI prot ID no annotation VI_04601 Bacilli_gi_418002674 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p152048 no NCBI prot ID no annotation VI_05153 Bacilli_gi_511644305_4233_44878 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p222666 no NCBI prot ID no annotation VI_00980 Bacilli_gi_423079685 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales; Siphoviridae; unclassified Siphoviridae.
p189641 no NCBI prot ID no annotation VI_04044 unknown_gi_546714669 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p124975 no NCBI prot ID no annotation VI_01271 Clostridia_gi_548190329 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.
p288035 no NCBI prot ID no annotation VI_04183 Alphaproteobacteria_gi_306840416 Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes; Caudovirales.

PHROGs colocalized to this PHROG

PHROG #Prot Annotation Category #Neighbors Probability Score
phrog_83 1008 terminase small subunit head and packaging 13 7.59E-30 20.24
phrog_10715 10 hydrolase other 6 1.69E-28 18.89
phrog_1066 140 no annotation unknown function 4 2.19E-13 3.78
phrog_12885 8 no annotation unknown function 2 1.02E-11 2.11

PHROGs similar to this PHROG

PHROG Annotation Category Probability Evalue posQ/posS
phrog_10255 kinase other 95.4 0.00064 121-225 / 1-96
phrog_1035 endonuclease VII DNA, RNA and nucleotide metabolism 96.4 4.2E-05 58-109 / 97-154
phrog_10378 HNH endonuclease DNA, RNA and nucleotide metabolism 93.3 0.011 29-105 / 81-150
phrog_11604 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2.1E-05 52-112 / 65-135
phrog_119 HNH endonuclease DNA, RNA and nucleotide metabolism 99.8 2.8E-24 36-112 / 5-86
phrog_12400 HNH endonuclease DNA, RNA and nucleotide metabolism 93.0 0.014 40-107 / 10-86
phrog_124 Sak4-like ssDNA annealing protein DNA, RNA and nucleotide metabolism 95.1 0.0013 120-161 / 13-53
phrog_1271 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 3.5E-07 44-109 / 129-201
phrog_139 deoxynucleoside monophosphate kinase other 92.1 0.024 121-144 / 2-25
phrog_14314 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 6E-06 51-107 / 5-63
phrog_14322 no annotation unknown function 94.3 0.0041 118-157 / 191-236
phrog_144 HNH endonuclease DNA, RNA and nucleotide metabolism 99.8 7.2E-23 38-110 / 38-115
phrog_15103 no annotation unknown function 96.1 0.00011 45-107 / 185-253
phrog_1571 HNH endonuclease DNA, RNA and nucleotide metabolism 90.8 0.046 47-105 / 3-86
phrog_16726 HNH endonuclease DNA, RNA and nucleotide metabolism 97.4 4.9E-07 52-126 / 70-142
phrog_16986 no annotation unknown function 95.3 0.00086 45-168 / 3-132
phrog_17283 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00012 72-109 / 8-44
phrog_1815 guanylate kinase other 94.0 0.0056 121-235 / 2-136
phrog_197 Zot-like toxin moron, auxiliary metabolic gene and host takeover 93.8 0.0066 121-141 / 1-21
phrog_1985 HNH endonuclease DNA, RNA and nucleotide metabolism 95.4 0.00064 62-109 / 67-129
phrog_2071 ATPase other 99.3 4.4E-16 120-235 / 2-119
phrog_2118 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 2.3E-05 51-108 / 5-74
phrog_2214 HNH endonuclease DNA, RNA and nucleotide metabolism 97.3 1.1E-06 52-112 / 25-84
phrog_2323 HNH endonuclease DNA, RNA and nucleotide metabolism 99.0 1.9E-13 42-114 / 5-95
phrog_239 DNA primase/helicase DNA, RNA and nucleotide metabolism 93.2 0.012 116-232 / 303-437
phrog_24030 RNA ligase DNA, RNA and nucleotide metabolism 96.4 5E-05 52-104 / 8-61
phrog_24252 HNH endonuclease DNA, RNA and nucleotide metabolism 92.2 0.022 52-109 / 5-73
phrog_243 DnaB-like replicative helicase DNA, RNA and nucleotide metabolism 91.6 0.032 115-149 / 29-63
phrog_2914 endonuclease VII DNA, RNA and nucleotide metabolism 91.1 0.04 52-108 / 28-81
phrog_296 DNA transposition protein integration and excision 92.4 0.02 77-162 / 63-143
phrog_30443 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 9.2E-05 46-105 / 44-103
phrog_3106 HNH endonuclease DNA, RNA and nucleotide metabolism 96.9 7.1E-06 37-110 / 11-108
phrog_333 HNH endonuclease DNA, RNA and nucleotide metabolism 99.1 7.8E-14 47-113 / 13-78
phrog_338 HNH endonuclease DNA, RNA and nucleotide metabolism 98.4 2.3E-10 49-111 / 13-86
phrog_3757 no annotation unknown function 94.0 0.0054 117-165 / 122-173
phrog_4160 no annotation unknown function 93.2 0.011 51-109 / 49-118
phrog_4182 no annotation unknown function 94.6 0.0027 121-243 / 2-109
phrog_4234 HNH endonuclease DNA, RNA and nucleotide metabolism 95.7 0.00033 60-140 / 25-117
phrog_4321 HNH endonuclease DNA, RNA and nucleotide metabolism 96.1 0.00013 28-109 / 30-116
phrog_505 polynucleotide kinase other 97.5 1.9E-07 121-261 / 2-142
phrog_5104 no annotation unknown function 91.2 0.038 48-105 / 136-206
phrog_5200 HNH endonuclease DNA, RNA and nucleotide metabolism 94.7 0.0023 44-117 / 22-96
phrog_5484 DnaA-like replication initiation protein DNA, RNA and nucleotide metabolism 94.9 0.0017 120-143 / 26-49
phrog_5718 HNH endonuclease DNA, RNA and nucleotide metabolism 98.1 3E-09 50-109 / 11-72
phrog_5846 clamp loader of DNA polymerase DNA, RNA and nucleotide metabolism 97.0 4E-06 122-232 / 39-165
phrog_589 HNH endonuclease DNA, RNA and nucleotide metabolism 99.8 5.1E-23 32-114 / 20-105
phrog_5956 HNH endonuclease DNA, RNA and nucleotide metabolism 99.2 1.4E-14 57-114 / 1-63
phrog_6050 HNH endonuclease DNA, RNA and nucleotide metabolism 98.4 1.8E-10 61-110 / 4-56
phrog_6891 ATPase other 95.5 0.00062 120-225 / 33-125
phrog_6931 no annotation unknown function 95.8 0.00032 117-233 / 183-309
phrog_7370 HNH endonuclease DNA, RNA and nucleotide metabolism 95.9 0.0002 52-108 / 31-86
phrog_740 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 1.9E-07 52-109 / 8-70
phrog_761 thymidylate kinase other 93.2 0.011 121-236 / 2-138
phrog_7785 HNH endonuclease DNA, RNA and nucleotide metabolism 97.9 1.8E-08 54-109 / 60-113
phrog_800 terminase small subunit head and packaging 95.0 0.0014 122-235 / 9-138
phrog_8048 HNH endonuclease DNA, RNA and nucleotide metabolism 97.5 2.1E-07 46-104 / 11-75
phrog_8238 RNA ligase DNA, RNA and nucleotide metabolism 94.0 0.0055 122-235 / 3-124
phrog_8446 HNH endonuclease DNA, RNA and nucleotide metabolism 98.3 5.8E-10 45-105 / 112-184
phrog_8660 HNH endonuclease DNA, RNA and nucleotide metabolism 96.6 1.9E-05 54-109 / 102-156
phrog_9545 HNH endonuclease DNA, RNA and nucleotide metabolism 95.0 0.0014 36-107 / 91-166
phrog_960 HNH endonuclease DNA, RNA and nucleotide metabolism 93.5 0.0086 64-111 / 41-90
phrog_9644 head maturation protease head and packaging 99.5 9.5E-19 121-261 / 2-136
phrog_9645 HNH endonuclease DNA, RNA and nucleotide metabolism 96.2 9.5E-05 54-114 / 16-81

PFAMs similar to this PHROG

ID Definition Evalue posQ/posS
PF03668.14 P-loop ATPase protein family 1.4E-07 124-152 / 1-29
PF13395.5 HNH endonuclease 0.00058 301-333 / 18-50
PF09665.9 Type II restriction endonuclease (RE_Alw26IDE) 1.6E-05 65-112 / 253-297
PF01844.22 HNH endonuclease 0.00053 291-333 / 1-47
PF05766.11 Bacteriophage Lambda NinG protein 0.00066 363-421 / 84-138
PF05315.10 ICEA Protein 0.00035 276-334 / 81-150
PF00625.20 Guanylate kinase 9.8E-07 124-148 / 2-26
PF14279.5 HNH endonuclease 0.0052 291-333 / 1-44
PF13671.5 AAA domain 1.2E-06 126-156 / 1-32
PF06414.11 Zeta toxin 1.4E-06 121-157 / 11-50
PF13238.5 AAA domain 1.5E-06 127-148 / 1-22
PF08433.9 Chromatin associated protein KTI12 1.6E-06 124-147 / 1-24
PF07931.11 Chloramphenicol phosphotransferase-like protein 1.7E-06 124-148 / 1-25
PF01745.15 Isopentenyl transferase 2.2E-06 124-157 / 1-35
PF13189.5 Cytidylate kinase-like family 3.9E-06 126-147 / 1-22
PF00406.21 Adenylate kinase 4E-06 129-156 / 1-29
PF01591.17 6-phosphofructo-2-kinase 7.7E-06 121-147 / 6-32
PF01712.18 Deoxynucleoside kinase 8.2E-06 127-148 / 1-22
PF13207.5 AAA domain 1E-05 130-157 / 1-29
PF01583.19 Adenylylsulphate kinase 3.4E-05 124-147 / 2-25
PF01202.21 Shikimate kinase 3.5E-05 219-241 / 84-106
PF03976.13 Polyphosphate kinase 2 (PPK2) 3.8E-05 122-147 / 26-51
PF13391.5 HNH endonuclease 0.00074 368-419 / 1-45
PF01121.19 Dephospho-CoA kinase 8E-05 125-156 / 1-33
PF06147.10 Protein of unknown function (DUF968) 0.00012 64-111 / 126-174
PF13521.5 AAA domain 0.00013 126-147 / 1-22
PF08303.10 tRNA ligase kinase domain 0.00017 126-147 / 1-22
PF00485.17 Phosphoribulokinase / Uridine kinase family 0.00025 126-147 / 1-22
PF02224.17 Cytidylate kinase 0.0003 127-148 / 1-22
PF02223.16 Thymidylate kinase 0.00068 129-147 / 1-19
PF13173.5 AAA domain 0.0011 124-147 / 2-25
PF00910.21 RNA helicase 0.0016 127-147 / 1-21
PF03266.14 NTPase 0.0017 127-147 / 2-22
PF10649.8 Protein of unknown function (DUF2478) 0.0019 127-147 / 1-21
PF05729.11 NACHT domain 0.002 126-147 / 2-23
PF04275.13 Phosphomevalonate kinase 0.002 129-147 / 1-19
PF07475.11 HPr Serine kinase C-terminal domain 0.0021 123-152 / 13-42
PF05272.10 Virulence-associated protein E 0.0024 123-147 / 58-82
PF02702.16 Osmosensitive K+ channel His kinase sensor domain 0.003 123-147 / 3-27
PF13401.5 AAA domain 0.0035 123-147 / 4-28
PF00004.28 ATPase family associated with various cellular activities (AAA) 0.0035 127-147 / 1-21
PF00308.17 Bacterial dnaA protein 0.0036 124-147 / 33-56
PF05496.11 Holliday junction DNA helicase ruvB N-terminus 0.0037 123-147 / 44-68
PF02283.15 Cobinamide kinase / cobinamide phosphate guanyltransferase 0.0039 127-147 / 1-21
PF02572.14 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 0.004 126-147 / 2-23
PF03215.14 Rad17 cell cycle checkpoint protein 0.0041 123-147 / 44-68
PF01637.17 ATPase domain predominantly from Archaea 0.0041 123-147 / 19-43
PF00265.17 Thymidine kinase 0.0042 125-147 / 2-24
PF07728.13 AAA domain (dynein-related subfamily) 0.0042 127-147 / 2-22
PF01443.17 Viral (Superfamily 1) RNA helicase 0.0047 127-147 / 1-20
PF06431.10 Polyomavirus large T antigen C-terminus 0.0048 123-147 / 154-178
PF05707.11 Zonular occludens toxin (Zot) 0.0048 125-144 / 1-20
PF05621.10 Bacterial TniB protein 0.005 125-147 / 39-61
PF04851.14 Type III restriction enzyme, res subunit 0.005 123-147 / 22-46
PF04665.11 Poxvirus A32 protein 0.0057 122-147 / 11-36
PF00158.25 Sigma-54 interaction domain 0.0062 123-147 / 21-45
PF07726.10 ATPase family associated with various cellular activities (AAA) 0.0063 127-147 / 2-22
PF12775.6 P-loop containing dynein motor region D3 0.0064 124-147 / 33-56
PF05673.12 Protein of unknown function (DUF815) 0.0064 123-147 / 53-77
PF09820.8 Predicted AAA-ATPase 0.0064 124-147 / 31-54
PF01926.22 50S ribosome-binding GTPase 0.0065 127-147 / 2-22
PF00006.24 ATP synthase alpha/beta family, nucleotide-binding domain 0.0067 123-147 / 13-37
PF02492.18 CobW/HypB/UreG, nucleotide-binding domain 0.0069 125-145 / 1-21
PF12774.6 Hydrolytic ATP binding site of dynein motor region D1 0.0072 124-147 / 32-55
PF14532.5 Sigma-54 interaction domain 0.0075 124-147 / 21-44
PF13191.5 AAA ATPase domain 0.0075 124-147 / 24-47
PF07693.13 KAP family P-loop domain 0.0076 122-147 / 29-54
PF01695.16 IstB-like ATP binding protein 0.0077 123-147 / 47-71
PF09848.8 Uncharacterized conserved protein (DUF2075) 0.008 125-148 / 2-25
PF13177.5 DNA polymerase III, delta subunit 0.0083 124-147 / 19-42

Annotations of the NCBI proteins of this PHROG


3:hypothetical protein 1:ABC transporter ATP-binding protein 1:small terminase subunit 1:ATPase 1:HNH endonuclease domain protein 1:terminase small subunit 1:HNH endonuclease

KEGG orthologous groups similar to this PHROG

ID Name : Definition Pathways BestScore #Hits
no KEGG group similar to this PHROG                                                            

GO terms in Uniprot proteins similar to this PHROG

ID Definition
GO:0008134 transcription factor binding
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation
GO:0000160 phosphorelay signal transduction system
GO:0009236 cobalamin biosynthetic process
GO:0016887 ATPase activity
GO:0004140 dephospho-CoA kinase activity
GO:0051188 cofactor biosynthetic process
GO:0016020 membrane
GO:0006139 nucleobase-containing compound metabolic process
GO:0003724 RNA helicase activity
GO:0015937 coenzyme A biosynthetic process
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0006000 fructose metabolic process
GO:0000166 nucleotide binding
GO:0016740 transferase activity
GO:0003972 RNA ligase (ATP) activity
GO:0004673 protein histidine kinase activity
GO:0004161 dimethylallyltranstransferase activity
GO:0006695 cholesterol biosynthetic process
GO:0003677 DNA binding
GO:0006310 DNA recombination
GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity
GO:0043752 adenosylcobinamide kinase activity
GO:0009378 four-way junction helicase activity
GO:0016787 hydrolase activity
GO:0004127 cytidylate kinase activity
GO:0006260 DNA replication
GO:0003873 6-phosphofructo-2-kinase activity
GO:0098519 nucleotide phosphatase activity, acting on free nucleotides
GO:0005524 ATP binding
GO:0003723 RNA binding
GO:0006109 regulation of carbohydrate metabolic process
GO:0006281 DNA repair
GO:0016301 kinase activity
GO:0008152 metabolic process
GO:0004631 phosphomevalonate kinase activity
GO:0005525 GTP binding
GO:0004797 thymidine kinase activity
GO:0009058 biosynthetic process
GO:0000155 phosphorelay sensor kinase activity
GO:0004672 protein kinase activity

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